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IMGVR_UViG_3300028601_000032-3300028601-Ga0265295_100060018
Arc-VirIMGVR_UViG_3300028601_000032-3300028601-Ga0265295_100060018
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 5-46
Domain cluster:
representative
CATH (70)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3dorA03 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.76 | 66.0 | 4.02e-01 | 100.0% | 23.2% |
| 2b3uB00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.74 | 63.0 | 4.21e-01 | 100.0% | 31.1% |
| 4mfzA02 | 3.40.630.120 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › | 0.71 | 58.0 | 4.09e-01 | 100.0% | 40.8% |
| 2zyzC00 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.70 | 58.0 | 4.60e-01 | 100.0% | 47.9% |
| 3evtA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.70 | 47.0 | 3.40e-01 | 90.5% | 23.3% |
| 2bh1X00 | 3.30.300.160 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Type II secretion system, protein E, N-terminal domain | 0.70 | 55.0 | 4.88e-01 | 100.0% | 58.8% |
| 1wteA02 | 3.40.1560.10 | Alpha Beta › 3-Layer(aba) Sandwich › type ii restriction endonuclease, domain 2 › type ii restriction endonuclease, domain 2 | 0.69 | 58.0 | 4.26e-01 | 100.0% | 44.4% |
| 2os5A00 | 3.30.429.10 | Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor | 0.68 | 55.0 | 4.19e-01 | 100.0% | 83.9% |
| 2vldA02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.68 | 56.0 | 4.29e-01 | 100.0% | 76.1% |
| 2plqA00 | 3.60.110.10 | Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase | 0.67 | 55.0 | 3.30e-01 | 100.0% | 16.8% |
| 1amuA04 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.66 | 57.0 | 4.41e-01 | 100.0% | 51.0% |
| 3pbkA02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.66 | 54.0 | 4.18e-01 | 100.0% | 50.9% |
| 4alzA01 | 3.30.1340.30 | Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › | 0.66 | 54.0 | 4.90e-01 | 100.0% | 67.7% |
| 7nadx01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 50.0 | 3.23e-01 | 85.7% | 39.5% |
| 1p65A00 | 6.10.140.90 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 34.0 | 3.05e-01 | 85.7% | 31.6% |
| 3g9kF01 | 3.60.20.40 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Gamma-glutamyltranspeptidase, small (S) subunit | 0.66 | 45.0 | 3.09e-01 | 100.0% | 19.0% |
| 2ed6A01 | 2.60.40.2770 | Mainly Beta › Sandwich › Immunoglobulin-like › WSSV envelope protein-like | 0.66 | 47.0 | 3.28e-01 | 100.0% | 21.4% |
| 3n8hA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.66 | 49.0 | 3.33e-01 | 85.7% | 42.6% |
| 6rftA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.65 | 52.0 | 3.87e-01 | 100.0% | 40.5% |
| 3r1kA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.65 | 52.0 | 3.85e-01 | 100.0% | 41.4% |
| 6lkvA01 | 3.30.429.10 | Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor | 0.64 | 50.0 | 3.72e-01 | 97.6% | 74.4% |
| 3nyqA02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.63 | 54.0 | 4.39e-01 | 100.0% | 60.5% |
| 4isbB02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.63 | 49.0 | 3.91e-01 | 100.0% | 56.1% |
| 8affD01 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.63 | 53.0 | 4.47e-01 | 100.0% | 65.4% |
| 2h1eA02 | 2.40.50.40 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.63 | 47.0 | 4.33e-01 | 81.0% | 89.1% |
| 3iplA02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.63 | 51.0 | 4.26e-01 | 100.0% | 59.0% |
| 4gs5A02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.62 | 51.0 | 4.01e-01 | 100.0% | 49.5% |
| 1pkhB00 | 2.70.40.10 | Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) | 0.62 | 47.0 | 3.21e-01 | 88.1% | 33.7% |
| 1uwdA00 | 3.30.300.130 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Fe-S cluster assembly (FSCA) | 0.62 | 50.0 | 3.98e-01 | 100.0% | 51.0% |
| 1js3A03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.62 | 45.0 | 3.68e-01 | 85.7% | 37.1% |
| 6aieA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.62 | 51.0 | 3.47e-01 | 100.0% | 56.6% |
| 4iz6A02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.62 | 52.0 | 3.99e-01 | 100.0% | 47.2% |
| 2b8eB01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.62 | 52.0 | 3.81e-01 | 100.0% | 47.6% |
| 3i5xA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 48.0 | 3.03e-01 | 88.1% | 30.4% |
| 6upsA01 | 3.40.395.10 | Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A | 0.61 | 47.0 | 3.42e-01 | 100.0% | 31.0% |
| 4k6nA02 | 3.20.10.10 | Alpha Beta › Alpha-Beta Barrel › D-amino Acid Aminotransferase; Chain A, domain 2 › D-amino Acid Aminotransferase, subunit A, domain 2 | 0.61 | 51.0 | 3.56e-01 | 100.0% | 31.4% |
| 1vk0A00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.61 | 50.0 | 3.28e-01 | 97.6% | 38.5% |
| 1pv9B01 | 3.40.350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain | 0.60 | 52.0 | 3.78e-01 | 100.0% | 78.2% |
| 2proC01 | 3.30.300.50 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.60 | 47.0 | 4.08e-01 | 100.0% | 53.7% |
| 1yj7D02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.60 | 47.0 | 3.97e-01 | 100.0% | 58.6% |
| 2kz0A01 | 3.30.300.90 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › BolA-like | 0.59 | 42.0 | 3.72e-01 | 81.0% | 98.6% |
| 2oivA00 | 3.40.395.10 | Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A | 0.59 | 45.0 | 3.18e-01 | 100.0% | 27.1% |
| 1vjfA00 | 3.90.960.10 | Alpha Beta › Alpha-Beta Complex › YbaK protein › YbaK/aminoacyl-tRNA synthetase-associated domain | 0.58 | 50.0 | 3.35e-01 | 100.0% | 46.4% |
| 3gr0D01 | 3.30.70.1780 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 46.0 | 4.67e-01 | 97.6% | 97.6% |
| 7uvpA03 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.58 | 42.0 | 3.01e-01 | 83.3% | 77.2% |
| 3bt7A02 | 2.40.50.1070 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.58 | 44.0 | 3.29e-01 | 100.0% | 35.2% |
| 1apyB00 | 3.60.20.30 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › (Glycosyl)asparaginase | 0.58 | 42.0 | 3.10e-01 | 88.1% | 29.8% |
| 3vkgA07 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 41.0 | 2.50e-01 | 88.1% | 16.0% |
| 3ujpA02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.58 | 47.0 | 3.43e-01 | 90.5% | 53.0% |
| 2n6eA00 | 3.40.1530.20 | Alpha Beta › 3-Layer(aba) Sandwich › hypothetical protein tt1805 › Protein of unknown function (DUF1491) | 0.57 | 42.0 | 3.27e-01 | 85.7% | 90.0% |
| 2vqeL00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.57 | 48.0 | 3.51e-01 | 100.0% | 54.8% |
| 2c60A01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.56 | 40.0 | 3.34e-01 | 100.0% | 41.8% |
| 4nnzA01 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.56 | 43.0 | 2.96e-01 | 100.0% | 58.5% |
| 3zwbA01 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.56 | 44.0 | 2.78e-01 | 97.6% | 19.4% |
| 1s4nB00 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.56 | 45.0 | 2.74e-01 | 100.0% | 17.3% |
| 4k30A00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.56 | 42.0 | 3.11e-01 | 100.0% | 36.6% |
| 3rheA00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.55 | 47.0 | 3.49e-01 | 97.6% | 98.2% |
| 1j7xA02 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.55 | 47.0 | 3.01e-01 | 100.0% | 22.9% |
| 3b34A02 | 3.30.2010.30 | Alpha Beta › 2-Layer Sandwich › Zincin-like › | 0.55 | 48.0 | 3.81e-01 | 100.0% | 68.2% |
| 1yx1A00 | 3.20.20.150 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes | 0.55 | 43.0 | 2.78e-01 | 100.0% | 18.4% |
| 3kk7A01 | 3.30.420.400 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › | 0.54 | 46.0 | 3.49e-01 | 100.0% | 58.7% |
| 5je6A01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.54 | 40.0 | 2.70e-01 | 97.6% | 42.9% |
| 4bbyA02 | 3.30.160.650 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.54 | 34.0 | 3.37e-01 | 90.5% | 54.5% |
| 4qclA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.53 | 39.0 | 2.58e-01 | 100.0% | 20.3% |
| 3fvyA03 | 3.30.70.2600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 43.0 | 3.71e-01 | 100.0% | 62.7% |
| 3cfxA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.52 | 44.0 | 2.97e-01 | 100.0% | 53.5% |
| 1jrrA02 | 3.30.497.10 | Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 | 0.52 | 41.0 | 2.71e-01 | 95.2% | 35.3% |
| 3tssA02 | 2.40.50.110 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.52 | 45.0 | 3.81e-01 | 100.0% | 81.7% |
| 6djwA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.51 | 42.0 | 3.60e-01 | 95.2% | 93.1% |
| 2wvxA02 | 3.30.2080.10 | Alpha Beta › 2-Layer Sandwich › GH92 mannosidase fold › GH92 mannosidase domain | 0.50 | 39.0 | 2.74e-01 | 90.5% | 34.4% |
ECOD (81)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3408059 | 2496.1.1.2 ↗ | a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS | 0.84 | 73.0 | 5.08e-01 | 100.0% | 37.3% |
| 5009631 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.75 | 62.0 | 4.94e-01 | 97.6% | 54.4% |
| 2715553 | 2008.1.1.34 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Card1_endonuc | 0.75 | 62.0 | 4.60e-01 | 100.0% | 77.5% |
| 3362578 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.74 | 62.0 | 4.13e-01 | 100.0% | 30.6% |
| 4312317 | 2005.1.1.11 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 | 0.73 | 59.0 | 3.58e-01 | 88.1% | 46.3% |
| 4046575 | 286.1.1.2 ↗ | a+b complex topology › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › PhzC-PhzF | 0.73 | 60.0 | 4.51e-01 | 100.0% | 41.7% |
| 4494448 | 2008.1.1.183 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27227 | 0.72 | 60.0 | 4.29e-01 | 100.0% | 34.8% |
| 4669968 | 5104.1.1.0 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases | 0.72 | 60.0 | 4.51e-01 | 100.0% | 40.7% |
| 3821558 | 2008.1.1.27 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RAI1 | 0.72 | 60.0 | 3.56e-01 | 100.0% | 29.1% |
| 3925397 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.71 | 58.0 | 4.55e-01 | 100.0% | 52.0% |
| 3961441 | 327.5.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C | 0.71 | 60.0 | 5.07e-01 | 100.0% | 65.3% |
| 3999982 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.71 | 60.0 | 5.04e-01 | 100.0% | 74.7% |
| 1171244 | 2008.2.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like | 0.70 | 58.0 | 4.60e-01 | 100.0% | 47.9% |
| 5037715 | 2002.1.1.60 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › AP_endonuc_2 | 0.70 | 48.0 | 2.91e-01 | 73.8% | 11.1% |
| 3295051 | 327.5.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C | 0.70 | 60.0 | 4.43e-01 | 100.0% | 47.0% |
| 3363171 | 2002.1.1.11 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PK | 0.70 | 56.0 | 3.83e-01 | 97.6% | 28.8% |
| 3675211 | 246.3.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos | 0.69 | 58.0 | 3.67e-01 | 100.0% | 21.3% |
| 4301550 | 327.5.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C | 0.69 | 57.0 | 4.41e-01 | 100.0% | 51.4% |
| 3963030 | 213.1.1.29 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_9 | 0.68 | 56.0 | 3.87e-01 | 100.0% | 33.3% |
| 3453248 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.67 | 42.0 | 3.83e-01 | 97.6% | 49.1% |
| 4942754 | 2496.1.1.0 ↗ | a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like | 0.67 | 54.0 | 4.45e-01 | 97.6% | 100.0% |
| 4954702 | 2008.1.1.114 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF4143 | 0.67 | 51.0 | 3.91e-01 | 100.0% | 33.3% |
| 4457355 | 213.1.1.29 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_9 | 0.66 | 53.0 | 3.93e-01 | 100.0% | 40.7% |
| 3257192 | 2003.1.1.143 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NmrA, NAD_binding_10 | 0.66 | 55.0 | 3.32e-01 | 100.0% | 26.9% |
| 3255636 | 246.1.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase | 0.66 | 54.0 | 3.30e-01 | 100.0% | 19.3% |
| 5047552 | 2008.1.1.201 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_CfrBI | 0.66 | 54.0 | 3.33e-01 | 100.0% | 27.0% |
| 3520913 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.66 | 48.0 | 2.66e-01 | 78.6% | 33.5% |
| 4927819 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.65 | 52.0 | 4.38e-01 | 97.6% | 76.2% |
| 3978722 | 3261.1.1.2 ↗ | a+b two layers › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb › Yop-YscD_ppl_1st | 0.64 | 51.0 | 4.73e-01 | 100.0% | 68.3% |
| 4991304 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.64 | 52.0 | 4.50e-01 | 100.0% | 62.7% |
| 2634195 | 2008.1.1.49 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_SinI | 0.64 | 50.0 | 3.27e-01 | 100.0% | 28.9% |
| 5025458 | 2008.1.1.114 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF4143 | 0.64 | 49.0 | 4.19e-01 | 100.0% | 48.2% |
| 4930769 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.64 | 50.0 | 3.98e-01 | 100.0% | 61.0% |
| 4934962 | 327.18.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A | 0.64 | 55.0 | 4.80e-01 | 100.0% | 73.8% |
| 4962337 | 327.6.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like › FeS_assembly_P | 0.64 | 56.0 | 4.20e-01 | 100.0% | 49.5% |
| 3444901 | 4954.1.1.0 ↗ | a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit | 0.64 | 52.0 | 3.56e-01 | 100.0% | 29.7% |
| 4928783 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.64 | 46.0 | 4.25e-01 | 85.7% | 57.1% |
| 5004463 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.64 | 46.0 | 2.82e-01 | 83.3% | 70.0% |
| 4592995 | 327.5.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C | 0.63 | 52.0 | 4.01e-01 | 100.0% | 45.0% |
| 5011218 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.63 | 53.0 | 4.33e-01 | 100.0% | 61.2% |
| 1155906 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.62 | 51.0 | 4.01e-01 | 100.0% | 49.5% |
| 3403495 | 2484.3.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › Creatinase/prolidase N-terminal domain › Creatinase/prolidase N-terminal domain › AMP_N | 0.62 | 48.0 | 3.40e-01 | 100.0% | 25.0% |
| 3987395 | 327.5.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C | 0.62 | 51.0 | 4.14e-01 | 100.0% | 53.3% |
| 4372720 | 70.2.1.5 ↗ | beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD | 0.62 | 47.0 | 3.10e-01 | 88.1% | 29.5% |
| 4247735 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.62 | 50.0 | 2.76e-01 | 100.0% | 20.1% |
| 3588726 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.61 | 48.0 | 4.01e-01 | 100.0% | 51.1% |
| 1421547 | 327.10.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › Ribosomal_S7e | 0.61 | 52.0 | 4.16e-01 | 100.0% | 56.8% |
| 5039350 | 327.6.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like › FeS_assembly_P | 0.61 | 48.0 | 3.89e-01 | 100.0% | 56.0% |
| 3388342 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.61 | 48.0 | 4.19e-01 | 100.0% | 69.3% |
| 4191800 | 3075.1.1.0 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA | 0.61 | 47.0 | 4.30e-01 | 85.7% | 67.3% |
| 363486 | 327.13.1.3 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system › PrgH | 0.61 | 49.0 | 4.68e-01 | 97.6% | 76.9% |
| 4392521 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.61 | 51.0 | 3.13e-01 | 100.0% | 63.9% |
| 3620852 | 3075.1.1.0 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA | 0.61 | 46.0 | 4.29e-01 | 85.7% | 81.8% |
| 4982789 | 4076.3.1.0 ↗ | a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain | 0.61 | 37.0 | 3.20e-01 | 100.0% | 32.3% |
| 4947002 | 327.18.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A | 0.60 | 54.0 | 4.56e-01 | 100.0% | 72.5% |
| 5050094 | 2004.1.1.97 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MobB | 0.60 | 42.0 | 2.96e-01 | 83.3% | 20.0% |
| 3281823 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.60 | 44.0 | 3.03e-01 | 81.0% | 72.0% |
| 3167935 | 4045.1.1.1 ↗ | a+b two layers › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › Aminotran_4 | 0.60 | 50.0 | 3.50e-01 | 100.0% | 32.2% |
| 3612905 | 207.1.1.22 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_6 | 0.59 | 49.0 | 2.73e-01 | 100.0% | 7.2% |
| 4928507 | 327.18.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A | 0.59 | 48.0 | 3.38e-01 | 97.6% | 30.8% |
| 3743593 | 59.1.1.0 ↗ | beta complex topology › triple barrel › triple barrel › Rap30/74 interaction domains-like | 0.59 | 53.0 | 4.21e-01 | 100.0% | 96.2% |
| 3958367 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.59 | 45.0 | 4.28e-01 | 92.9% | 74.5% |
| 3972367 | 2486.1.1.0 ↗ | a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase | 0.59 | 47.0 | 3.30e-01 | 97.6% | 45.1% |
| 4449065 | 2003.1.5.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr | 0.58 | 44.0 | 2.70e-01 | 100.0% | 12.3% |
| 4028261 | 299.1.1.1 ↗ | a+b complex topology › YbaK/ProRS associated domain › YbaK/ProRS associated domain › YbaK/ProRS associated domain › tRNA_edit | 0.58 | 48.0 | 3.32e-01 | 100.0% | 70.9% |
| 3387181 | 327.12.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › UbiD C-terminal domain-like › UbiD C-terminal domain-like | 0.58 | 45.0 | 3.48e-01 | 100.0% | 38.3% |
| 3945810 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.58 | 48.0 | 3.79e-01 | 100.0% | 49.0% |
| 4271270 | 2003.1.5.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr | 0.57 | 43.0 | 2.96e-01 | 100.0% | 20.9% |
| None | — | 0.57 | 44.0 | 2.71e-01 | 100.0% | 13.0% | |
| 5005699 | 327.11.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) | 0.57 | 48.0 | 4.29e-01 | 100.0% | 73.8% |
| 3709022 | 327.4.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain | 0.56 | 42.0 | 3.61e-01 | 100.0% | 68.9% |
| 4637167 | 2007.1.7.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes › DHQ_synthase | 0.56 | 43.0 | 3.05e-01 | 100.0% | 97.1% |
| 3278460 | 12.6.1.2 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Glyco_hydro_92 | 0.55 | 43.0 | 3.53e-01 | 90.5% | 64.7% |
| 3598535 | 324.1.1.0 ↗ | a+b two layers › OsmC-like › OsmC-like › OsmC-like | 0.55 | 41.0 | 3.54e-01 | 100.0% | 66.7% |
| 4951792 | 2498.1.1.9 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 | 0.55 | 47.0 | 2.90e-01 | 100.0% | 22.7% |
| 3518192 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.54 | 41.0 | 4.00e-01 | 92.9% | 75.6% |
| 3798928 | 59.1.4.2 ↗ | beta complex topology › triple barrel › triple barrel › TFIID subunits TAF1-TAF7 › DUF3591 | 0.53 | 39.0 | 2.26e-01 | 76.2% | 65.8% |
| 2325225 | 12.6.1.2 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Glyco_hydro_92 | 0.53 | 40.0 | 3.38e-01 | 90.5% | 67.9% |
| 3338405 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.52 | 44.0 | 3.56e-01 | 97.6% | 72.9% |
| 5082360 | 12.6.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related | 0.52 | 39.0 | 3.30e-01 | 90.5% | 64.7% |
| 5083962 | 12.6.1.2 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Glyco_hydro_92 | 0.52 | 40.0 | 3.21e-01 | 90.5% | 58.9% |