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IMGVR_UViG_3300028602_000031-3300028602-Ga0265294_1000081871

Arc-Vir

IMGVR_UViG_3300028602_000031-3300028602-Ga0265294_1000081871

Quality

85.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 471-566
PDB
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u2wD00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.85 47.0 4.78e-01 100.0% 56.4%
2dk5A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.85 56.0 6.73e-01 95.8% 98.5%
2jt1A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.83 57.0 6.63e-01 95.8% 95.8%
5tjjA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.81 55.0 6.26e-01 100.0% 90.4%
3w6kC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.79 52.0 5.47e-01 95.8% 74.7%
7dvrA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 56.0 4.90e-01 100.0% 51.1%
5trdA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 56.0 5.95e-01 100.0% 85.7%
2rasA01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.76 47.0 3.64e-01 100.0% 30.9%
2obpA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 56.0 6.09e-01 100.0% 92.6%
2gfnA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.75 46.0 3.56e-01 100.0% 30.7%
3bhqA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.74 45.0 3.48e-01 100.0% 29.2%
3cjdA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.74 45.0 3.58e-01 99.0% 32.4%
1j5yA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 47.0 5.56e-01 95.8% 96.9%
3dewA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.73 40.0 5.28e-01 93.8% 100.0%
2dg8D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.73 45.0 3.62e-01 100.0% 34.1%
3rh2A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.72 44.0 3.38e-01 100.0% 28.2%
3c07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.72 44.0 3.36e-01 100.0% 27.6%
3nnrA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.72 44.0 3.41e-01 100.0% 29.2%
2dt5B01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 47.0 5.32e-01 99.0% 87.7%
3vuqB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.71 44.0 3.52e-01 100.0% 33.5%
3pasA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.71 44.0 3.46e-01 100.0% 31.1%
3keoA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 47.0 5.33e-01 100.0% 90.3%
3qkxB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.71 44.0 3.51e-01 100.0% 33.1%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.71 44.0 3.37e-01 99.0% 29.3%
3htaC00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.70 45.0 3.52e-01 100.0% 32.8%
2oi8A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.70 43.0 3.34e-01 99.0% 29.6%
1d8jA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 49.0 5.32e-01 97.9% 87.7%
3e7qA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.69 42.0 3.28e-01 100.0% 28.4%
2v79A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 49.0 4.64e-01 99.0% 65.2%
2cduA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.65 34.0 3.26e-01 72.9% 41.6%
2y75A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 55.0 4.95e-01 100.0% 86.4%
3k69A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 51.0 4.41e-01 100.0% 86.0%
1l3iA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 41.0 3.42e-01 81.2% 89.2%
1ok8A03 3.30.387.10 Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 3 › Viral Envelope Glycoprotein, domain 3 0.53 32.0 3.43e-01 88.5% 70.4%
3ppbA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 42.0 3.45e-01 89.6% 67.6%
3iabB01 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.51 39.0 3.94e-01 95.8% 79.8%
2igtA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 39.0 2.97e-01 83.3% 75.8%
2qtqB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 43.0 3.41e-01 100.0% 45.2%
1dfaA03 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.50 41.0 4.13e-01 100.0% 93.7%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3311973 101.1.2.97 alpha arrays › HTH › HTH › winged helix domain › RPA_C 0.89 55.0 6.47e-01 92.7% 87.1%
4986964 101.1.2.46 alpha arrays › HTH › HTH › winged helix domain › HrcA_DNA-bdg 0.87 63.0 6.67e-01 100.0% 83.5%
5031727 101.1.2.150 alpha arrays › HTH › HTH › winged helix domain › HTH_45 0.82 61.0 6.15e-01 100.0% 77.9%
4945701 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.81 55.0 5.88e-01 93.8% 78.8%
3515741 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 65.0 6.61e-01 100.0% 87.4%
3974144 101.1.1.5 alpha arrays › HTH › HTH › Three-helical HTH › TetR_N 0.73 44.0 4.99e-01 100.0% 78.7%
5067037 101.1.2.142 alpha arrays › HTH › HTH › winged helix domain › HTH_Crp_2 0.73 52.0 5.63e-01 100.0% 88.7%
3968664 101.1.1.5 alpha arrays › HTH › HTH › Three-helical HTH › TetR_N 0.72 44.0 4.86e-01 100.0% 75.0%
142581 101.1.1.5 alpha arrays › HTH › HTH › Three-helical HTH › TetR_N 0.72 44.0 4.88e-01 100.0% 77.6%
3718412 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.70 62.0 4.23e-01 100.0% 29.8%
2547 101.1.1.5 alpha arrays › HTH › HTH › Three-helical HTH › TetR_N 0.69 42.0 4.77e-01 99.0% 78.7%
3290705 101.1.2.81 alpha arrays › HTH › HTH › winged helix domain › Put_DNA-bind_N 0.68 48.0 5.09e-01 100.0% 82.4%
3283567 101.1.1.5 alpha arrays › HTH › HTH › Three-helical HTH › TetR_N 0.68 42.0 4.73e-01 100.0% 80.0%
4941505 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.67 35.0 4.23e-01 95.8% 76.9%
4230774 101.1.9.117 alpha arrays › HTH › HTH › Putative DNA-binding domain › IF2_assoc 0.64 32.0 3.30e-01 85.4% 49.5%
4367442 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.63 59.0 5.15e-01 100.0% 83.6%
3939681 5001.1.1.41 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.61 43.0 2.98e-01 74.0% 59.1%
4935509 11.1.4.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.58 34.0 3.50e-01 83.3% 62.2%
3454218 109.4.1.890 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_CNRKL1_C 0.53 42.0 3.33e-01 95.8% 39.5%
3273636 328.1.1.0 a+b two layers › IF3-like › AlbA-like › AlbA-like 0.52 34.0 4.08e-01 75.0% 98.5%
3696797 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.51 38.0 2.53e-01 79.2% 30.1%
3675745 328.1.1.1 a+b two layers › IF3-like › AlbA-like › AlbA-like › Alba 0.51 32.0 3.58e-01 76.0% 82.2%
4552467 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.50 44.0 3.07e-01 99.0% 75.3%
D2 medium residues 14-76
PDB
Domain cluster: representative
CATH (67)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.76 68.0 5.55e-01 100.0% 92.3%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.76 67.0 5.62e-01 100.0% 93.6%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.76 68.0 5.62e-01 100.0% 93.6%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.73 65.0 5.43e-01 100.0% 93.6%
1kxpD04 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.73 51.0 4.78e-01 77.8% 59.7%
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.73 46.0 5.17e-01 77.8% 83.7%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.73 63.0 5.90e-01 96.8% 97.4%
7s0rB01 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.72 51.0 4.79e-01 81.0% 61.8%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.72 49.0 4.84e-01 96.8% 67.2%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.70 50.0 4.07e-01 76.2% 41.3%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.69 51.0 4.67e-01 88.9% 60.5%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.69 47.0 3.52e-01 71.4% 96.7%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.68 61.0 5.26e-01 100.0% 93.9%
3t69A02 3.30.420.310 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, C-terminal domain 0.68 57.0 3.93e-01 98.4% 26.5%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 50.0 4.88e-01 90.5% 70.4%
3t9oB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.68 56.0 4.56e-01 92.1% 65.8%
3ed5A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.68 45.0 4.09e-01 71.4% 51.2%
3d7iB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.67 49.0 4.29e-01 85.7% 51.0%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 52.0 3.79e-01 96.8% 29.6%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.67 52.0 5.01e-01 85.7% 74.0%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 48.0 4.53e-01 92.1% 64.5%
2mpnA00 6.10.140.1340 Special › Helix non-globular › Helix Hairpins › 0.65 47.0 4.62e-01 76.2% 76.5%
6vvoC03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.65 49.0 4.41e-01 82.5% 100.0%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.65 50.0 4.99e-01 84.1% 81.2%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.65 53.0 4.37e-01 90.5% 84.5%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.64 55.0 4.76e-01 100.0% 73.8%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.64 48.0 4.04e-01 88.9% 46.4%
2kjgA00 1.20.120.970 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.64 49.0 4.32e-01 88.9% 55.6%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 44.0 4.22e-01 88.9% 62.2%
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 47.0 3.96e-01 81.0% 78.4%
2i2xB01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.64 51.0 4.46e-01 90.5% 68.0%
6s6hA01 1.10.10.2830 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.63 43.0 3.65e-01 73.0% 41.3%
3e6sA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 55.0 4.11e-01 96.8% 84.3%
3ghyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.63 51.0 4.15e-01 90.5% 58.4%
1x3kA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.63 53.0 4.03e-01 93.7% 89.1%
2fp1B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.63 54.0 3.99e-01 96.8% 95.7%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 55.0 4.11e-01 100.0% 83.4%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 55.0 5.25e-01 98.4% 100.0%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 55.0 4.08e-01 100.0% 48.8%
2ew2A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.62 51.0 4.09e-01 95.2% 59.7%
2nn4A00 1.10.287.760 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like 0.62 47.0 4.77e-01 82.5% 100.0%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.62 49.0 4.63e-01 90.5% 91.1%
3hwrA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.62 51.0 4.11e-01 95.2% 56.6%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.61 45.0 4.48e-01 79.4% 74.2%
2jpnA00 1.20.1280.210 Mainly Alpha › Up-down Bundle › Monooxygenase › Uncharacterised protein UvsW.1 0.61 53.0 4.96e-01 100.0% 79.7%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.61 48.0 3.12e-01 87.3% 96.8%
2fe1A00 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.61 50.0 3.96e-01 90.5% 74.6%
1te2A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.61 50.0 4.77e-01 88.9% 84.7%
3qwwA03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 43.0 3.12e-01 77.8% 28.8%
1k8kG00 1.25.40.190 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5 0.59 43.0 3.36e-01 79.4% 36.0%
3qsgA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.59 50.0 4.12e-01 95.2% 84.3%
3w8hB00 1.10.12.70 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › 0.58 39.0 3.85e-01 71.4% 66.7%
2ygwA01 1.20.140.90 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain 0.58 50.0 3.79e-01 98.4% 41.8%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 47.0 4.54e-01 92.1% 95.9%
1np7A02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 46.0 3.83e-01 92.1% 56.3%
2w7nA00 1.10.10.2690 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.57 41.0 3.70e-01 90.5% 53.2%
1nxcA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.57 49.0 2.98e-01 100.0% 32.8%
3g0oA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.56 41.0 3.44e-01 81.0% 85.1%
2gf2A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.55 45.0 3.62e-01 93.7% 87.3%
4e21B02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.55 39.0 3.24e-01 81.0% 46.7%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.54 46.0 4.23e-01 100.0% 85.9%
3zdrA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.54 40.0 2.87e-01 81.0% 92.4%
3qdnA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 37.0 3.46e-01 73.0% 54.8%
8an5A01 3.30.460.40 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.53 45.0 3.25e-01 96.8% 88.5%
3fr3B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 41.0 3.53e-01 90.5% 63.5%
3vkgA10 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 43.0 3.18e-01 100.0% 36.2%
1qrvA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.52 47.0 4.43e-01 96.8% 86.3%
ECOD (60)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4536901 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.80 59.0 4.22e-01 77.8% 33.5%
3326759 284.1.3.1 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › SNF5 0.80 64.0 6.08e-01 100.0% 74.7%
4447311 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.78 70.0 4.98e-01 100.0% 98.3%
4203622 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.77 67.0 4.82e-01 95.2% 96.6%
4828003 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.77 69.0 5.53e-01 100.0% 89.3%
3708001 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.76 55.0 5.34e-01 76.2% 70.0%
3993135 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 68.0 4.80e-01 100.0% 77.9%
4362035 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.75 66.0 4.74e-01 100.0% 95.7%
3227955 2484.8.1.1 mixed a+b and a/b › Ribonuclease H-like › Separase pseudo-protease domain (PPD) › Separase pseudo-protease domain (PPD) › Peptidase_C50 0.73 63.0 4.10e-01 93.7% 25.4%
3680362 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.73 54.0 3.05e-01 77.8% 7.7%
3506760 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 52.0 4.02e-01 87.3% 36.2%
3752375 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.72 64.0 4.52e-01 100.0% 86.2%
3700089 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.71 51.0 5.13e-01 81.0% 73.8%
3907844 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.71 63.0 4.49e-01 100.0% 88.4%
3492325 109.4.1.602 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Dor1 0.70 59.0 4.37e-01 96.8% 36.5%
5021741 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.69 52.0 5.11e-01 82.5% 74.3%
4014257 129.1.1.0 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.69 57.0 4.39e-01 95.2% 58.0%
3383609 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.69 51.0 4.29e-01 79.4% 47.6%
4061821 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.68 51.0 4.74e-01 81.0% 68.8%
3776639 109.4.1.1420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Laa1_Sip1_HTR5, HEAT_HEATR5A 0.68 60.0 3.26e-01 100.0% 6.4%
3680744 109.4.1.1257 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 0.67 48.0 3.25e-01 81.0% 20.4%
2889550 4995.1.1.0 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like 0.67 55.0 4.98e-01 90.5% 69.0%
3897990 150.3.1.23 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL11 0.67 59.0 4.34e-01 100.0% 74.1%
3416035 104.1.1.0 alpha duplicates or obligate multimers › TFIIA, alpha-helical domain › TFIIA, alpha-helical domain › TFIIA, alpha-helical domain 0.67 52.0 5.49e-01 85.7% 100.0%
4109644 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.66 50.0 3.77e-01 96.8% 34.5%
3413603 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.66 48.0 3.52e-01 79.4% 32.2%
3451862 10.13.1.0 beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A 0.65 50.0 3.35e-01 81.0% 26.2%
3723174 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.65 51.0 4.84e-01 84.1% 72.0%
3597909 5094.1.1.0 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like 0.65 54.0 4.47e-01 96.8% 93.3%
4599957 101.8.1.0 alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases 0.65 50.0 3.78e-01 87.3% 41.2%
3485769 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.64 60.0 4.11e-01 100.0% 55.4%
3188597 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.64 57.0 5.05e-01 100.0% 93.3%
3440208 109.4.1.1305 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, PPR_long, TPR_24 0.63 45.0 3.00e-01 79.4% 17.2%
3276289 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.63 54.0 3.69e-01 95.2% 81.3%
3390898 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.62 54.0 4.69e-01 100.0% 97.0%
5067572 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.62 55.0 4.69e-01 100.0% 89.5%
3302926 109.4.1.1271 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, TPR_24 0.62 44.0 3.24e-01 84.1% 27.4%
3300278 109.4.1.1256 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 0.61 43.0 3.61e-01 84.1% 41.7%
3463192 109.4.1.1261 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long 0.61 43.0 3.80e-01 84.1% 49.0%
3343450 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.60 42.0 2.77e-01 85.7% 16.2%
3652408 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.60 53.0 4.64e-01 100.0% 73.7%
3615321 109.4.1.1 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 0.60 52.0 3.40e-01 100.0% 21.4%
5046302 7602.1.1.1 a/b three-layered sandwiches › Lactate racemase C-terminal domain › Lactate racemase C-terminal domain › Lactate racemase C-terminal domain › LarA_C 0.60 46.0 3.32e-01 85.7% 36.5%
5007608 633.22.1.0 alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) 0.60 48.0 3.97e-01 88.9% 90.4%
3665637 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.60 41.0 3.32e-01 77.8% 34.1%
135426 129.1.1.11 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C 0.60 50.0 4.03e-01 96.8% 58.5%
3684126 109.4.1.1269 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, E_motif 0.59 45.0 3.55e-01 90.5% 37.9%
3647433 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.59 45.0 3.03e-01 85.7% 19.3%
3454451 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.59 42.0 3.34e-01 81.0% 35.6%
3367285 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.59 43.0 3.77e-01 85.7% 50.0%
3305845 109.4.1.1256 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 0.59 41.0 3.60e-01 79.4% 47.0%
3712266 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.57 45.0 3.59e-01 90.5% 54.8%
3230343 109.54.1.1 alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 0.57 45.0 3.65e-01 90.5% 44.8%
3440461 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.56 40.0 2.79e-01 79.4% 19.6%
3462080 109.4.1.1383 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, Eplus_motif, E_motif 0.56 48.0 3.01e-01 100.0% 56.1%
4976370 109.4.1.207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 0.56 49.0 2.97e-01 96.8% 22.4%
3384796 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.55 42.0 3.69e-01 85.7% 79.0%
3612931 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 48.0 2.90e-01 100.0% 47.5%
3815090 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.53 38.0 3.38e-01 79.4% 51.0%
3464282 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.52 40.0 3.03e-01 85.7% 44.7%
D3 medium residues 82-156
PDB
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.75 59.0 5.17e-01 84.0% 94.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.72 60.0 5.12e-01 89.3% 89.7%
2ew2A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.68 52.0 4.34e-01 82.7% 58.2%
1vb5A01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.67 54.0 5.05e-01 89.3% 77.7%
3hwrA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.66 50.0 4.19e-01 81.3% 57.4%
3ghyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.66 50.0 4.26e-01 82.7% 59.2%
1hssA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.65 51.0 4.56e-01 86.7% 73.0%
4ragA02 1.10.10.430 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Phosphatase 2C, C-terminal domain suprefamily 0.65 51.0 5.28e-01 84.0% 95.6%
1q6aA00 1.10.1240.30 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain 0.64 55.0 4.88e-01 94.7% 86.9%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 49.0 4.26e-01 82.7% 81.9%
2nn4A00 1.10.287.760 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like 0.64 43.0 4.72e-01 70.7% 91.9%
2i2xB01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.64 51.0 4.69e-01 89.3% 85.0%
1vw4L02 1.10.246.170 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.63 53.0 5.17e-01 94.7% 98.8%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.63 48.0 3.87e-01 82.7% 78.9%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.62 48.0 4.75e-01 85.3% 97.5%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.61 49.0 4.06e-01 86.7% 75.6%
3rhfD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 50.0 3.43e-01 94.7% 24.4%
2j4bB00 1.25.40.500 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TFIID subunit TAF5, NTD2 domain 0.61 48.0 4.01e-01 86.7% 58.6%
1zbpA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 48.0 4.67e-01 96.0% 77.6%
2vixA03 1.20.1280.240 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.60 52.0 4.60e-01 100.0% 92.9%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.60 52.0 3.90e-01 100.0% 94.9%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 49.0 3.83e-01 90.7% 48.1%
3k9iA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 43.0 3.98e-01 82.7% 58.3%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.58 51.0 4.04e-01 98.7% 95.6%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.58 51.0 4.47e-01 100.0% 85.5%
1np7A02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 49.0 4.26e-01 96.0% 67.2%
3cegA00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.58 48.0 3.33e-01 96.0% 66.1%
5douA01 1.10.1030.10 Mainly Alpha › Orthogonal Bundle › Carbamoyl Phosphate Synthetase; Chain A, domain 4 › Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 0.57 49.0 3.80e-01 97.3% 49.1%
4u04B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 39.0 3.78e-01 89.3% 62.5%
2bvlA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 46.0 4.47e-01 96.0% 81.4%
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 44.0 3.96e-01 90.7% 70.3%
1nxcA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.55 48.0 2.99e-01 100.0% 33.6%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 47.0 4.58e-01 98.7% 100.0%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 44.0 4.48e-01 97.3% 93.3%
3kfwX03 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 42.0 4.19e-01 85.3% 88.2%
8g0lB01 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 45.0 2.92e-01 98.7% 21.1%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 37.0 3.37e-01 72.0% 85.1%
1tjcA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 38.0 3.62e-01 82.7% 64.2%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.52 44.0 4.49e-01 100.0% 98.6%
3qsgA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.50 43.0 3.79e-01 98.7% 87.0%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3773131 109.4.1.342 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SBF2 0.82 75.0 5.08e-01 100.0% 93.5%
3326759 284.1.3.1 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › SNF5 0.81 57.0 5.79e-01 82.7% 74.7%
5003619 4973.1.1.0 alpha bundles › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core 0.81 62.0 6.57e-01 81.3% 95.4%
4828003 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.79 59.0 4.98e-01 78.7% 86.0%
5048577 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.78 59.0 5.80e-01 80.0% 98.8%
3213165 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.78 56.0 5.52e-01 76.0% 76.2%
3661193 4198.1.1.2 alpha arrays › TerB-like › TerB-like › TerB-like › ThylakoidFormat 0.76 52.0 3.84e-01 70.7% 34.1%
3925233 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.75 57.0 6.02e-01 81.3% 98.5%
3708001 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.74 53.0 5.48e-01 74.7% 94.3%
4362035 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.73 60.0 4.42e-01 88.0% 95.7%
5072863 2004.1.3.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.72 58.0 4.27e-01 85.3% 94.1%
3530124 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.72 59.0 5.84e-01 90.7% 90.0%
4168740 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.72 51.0 3.87e-01 76.0% 34.4%
3604599 182.1.3.0 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX 0.71 56.0 5.05e-01 90.7% 63.0%
5044421 592.2.1.0 alpha arrays › PWI domain-like › YugE-like › YugE-like 0.69 53.0 5.26e-01 82.7% 80.0%
3227955 2484.8.1.1 mixed a+b and a/b › Ribonuclease H-like › Separase pseudo-protease domain (PPD) › Separase pseudo-protease domain (PPD) › Peptidase_C50 0.69 59.0 4.04e-01 94.7% 62.7%
4288489 4973.1.1.2 alpha bundles › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › DnaG_cat_HB 0.68 58.0 5.83e-01 97.3% 96.0%
3612768 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 54.0 4.86e-01 89.3% 70.0%
3904047 9.26.1.0 beta barrels › Lipocalins/Streptavidin 0.68 34.0 2.55e-01 78.7% 19.5%
3542152 397.7.1.7 few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 › BSMAP 0.68 53.0 5.00e-01 84.0% 74.4%
3183972 109.4.1.70 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.68 57.0 4.29e-01 97.3% 74.0%
3955920 608.1.1.0 alpha arrays › AhpD-like › AhpD-like › AhpD-like 0.67 50.0 4.46e-01 81.3% 87.3%
3472261 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 54.0 3.65e-01 94.7% 24.4%
5029911 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.66 48.0 5.30e-01 84.0% 100.0%
3276902 109.4.1.1224 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_DOCK9 0.64 55.0 3.75e-01 96.0% 55.9%
5079293 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.64 51.0 4.38e-01 89.3% 84.8%
3844868 6088.1.1.2 alpha arrays › Helical bundle domain in elongation factor 3A › Helical bundle domain in elongation factor 3A › Helical bundle domain in elongation factor 3A › PF26051 0.63 45.0 4.51e-01 74.7% 81.3%
3781595 1134.1.1.7 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 0.63 50.0 5.15e-01 85.3% 90.0%
3926946 592.1.1.0 alpha arrays › PWI domain-like › PWI domain › PWI domain 0.63 44.0 4.37e-01 73.3% 78.8%
4012164 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.62 48.0 5.11e-01 85.3% 100.0%
4108644 603.1.1.215 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27853 0.62 54.0 4.78e-01 97.3% 89.1%
3494026 109.4.1.70 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.61 52.0 4.39e-01 97.3% 83.0%
3672171 109.4.1.189 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 0.61 49.0 4.07e-01 89.3% 51.9%
3405876 592.2.1.12 alpha arrays › PWI domain-like › YugE-like › YugE-like › PF26051 0.60 44.0 4.50e-01 81.3% 82.7%
3798432 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.60 51.0 3.19e-01 98.7% 16.5%
3752135 109.4.1.919 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_SCC3-SA 0.58 50.0 3.41e-01 100.0% 46.3%
4984709 4995.1.1.1 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.58 45.0 4.50e-01 86.7% 98.8%
3453505 109.4.1.1293 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1 0.57 43.0 3.25e-01 92.0% 31.3%
2889550 4995.1.1.0 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like 0.57 49.0 4.75e-01 94.7% 96.4%
3721863 109.4.1.217 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fis1_TPR_N,Fis1_TPR_C 0.57 41.0 3.52e-01 89.3% 44.6%
3194704 109.6.1.3 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF_N 0.57 47.0 3.83e-01 96.0% 81.3%
3484929 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.56 45.0 4.14e-01 89.3% 93.0%
4021487 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 47.0 3.97e-01 92.0% 57.6%
3690358 109.6.1.2 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF,RasGEF_N 0.56 47.0 2.94e-01 96.0% 48.1%
3414979 109.4.1.217 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fis1_TPR_N,Fis1_TPR_C 0.55 45.0 3.78e-01 89.3% 60.0%
3797208 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.54 48.0 3.86e-01 100.0% 64.0%
4933151 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.52 39.0 4.07e-01 84.0% 88.6%
3276289 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.51 45.0 3.21e-01 98.7% 82.7%
D4 medium residues 167-198_357-386
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3d5lA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 35.0 4.03e-01 82.3% 95.6%
4ww7B00 3.30.2380.10 Alpha Beta › 2-Layer Sandwich › PF0523-like › CGI121/TPRKB 0.51 42.0 3.03e-01 90.3% 76.7%
D5 medium residues 199-356
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF27228.1 best MTBMA_p00010_2nd 97.9 9.20e-28 100.0% 72.4%
D6 medium residues 387-467_567-583
PDB
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3te6A02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.64 44.0 4.25e-01 71.4% 77.7%
3e70C01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.57 41.0 4.14e-01 75.5% 89.7%
3mr7A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.57 44.0 3.71e-01 84.7% 67.6%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.56 44.0 4.40e-01 84.7% 83.5%
4xaiB02 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.56 40.0 3.23e-01 75.5% 93.4%
1cvrA02 3.40.50.1460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 45.0 3.44e-01 91.8% 71.9%
2l2oA00 1.10.10.1540 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Costar domain 0.53 35.0 3.70e-01 73.5% 76.5%
2dy1A03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.52 38.0 4.22e-01 89.8% 100.0%
2xfvA00 3.10.260.30 Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › 0.51 39.0 3.77e-01 79.6% 94.4%
3di5A00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.50 36.0 3.23e-01 77.6% 93.3%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4180021 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.71 50.0 5.04e-01 73.5% 77.0%
3923713 148.1.1.0 alpha arrays › Histone-like › Histone-related › Histone 0.70 53.0 4.22e-01 79.6% 87.9%
3188710 148.1.3.212 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_13 0.67 47.0 4.63e-01 72.4% 75.2%
5050704 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.67 48.0 4.91e-01 74.5% 94.7%
3607337 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.66 45.0 4.70e-01 70.4% 76.7%
3781957 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.56 42.0 3.19e-01 77.6% 73.0%
3607385 2005.1.1.9 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › DNA_photolyase 0.54 42.0 3.30e-01 86.7% 72.6%