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IMGVR_UViG_3300029589_000028-3300029589-Ga0245106_10125627
Arc-VirIMGVR_UViG_3300029589_000028-3300029589-Ga0245106_10125627
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-50
Domain cluster:
rep: OP795451.1__WAK44833.1__X__00011__D2-57
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF10979.14 best | DUF2786 | 60.2 | 2.10e-16 | 81.2% | 95.0% |
CATH (49)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2rklF00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.93 | 68.0 | 6.58e-01 | 77.1% | 78.8% |
| 2oh3A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.92 | 71.0 | 4.85e-01 | 81.2% | 27.8% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.89 | 66.0 | 6.17e-01 | 79.2% | 64.4% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.89 | 68.0 | 4.31e-01 | 81.2% | 19.1% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.89 | 68.0 | 4.88e-01 | 81.2% | 34.7% |
| 3m1cB01 | 3.30.390.170 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › | 0.89 | 63.0 | 4.70e-01 | 81.2% | 33.0% |
| 6vw7B03 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.86 | 63.0 | 5.12e-01 | 77.1% | 47.6% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.86 | 63.0 | 5.37e-01 | 79.2% | 71.4% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.86 | 65.0 | 5.15e-01 | 81.2% | 48.9% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.86 | 64.0 | 5.70e-01 | 79.2% | 76.9% |
| 4hfkB00 | 1.20.120.1620 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.83 | 74.0 | 5.81e-01 | 100.0% | 84.7% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.83 | 60.0 | 4.63e-01 | 79.2% | 37.0% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.82 | 61.0 | 6.01e-01 | 81.2% | 84.3% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.81 | 59.0 | 3.94e-01 | 79.2% | 21.0% |
| 2y4tA02 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.80 | 60.0 | 5.86e-01 | 81.2% | 75.0% |
| 4asvA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.80 | 68.0 | 5.88e-01 | 100.0% | 69.6% |
| 2yevA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 59.0 | 5.14e-01 | 81.2% | 60.8% |
| 3l0iA01 | 1.20.120.1520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.79 | 68.0 | 4.64e-01 | 97.9% | 29.0% |
| 3p42A02 | 6.10.250.2280 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.78 | 56.0 | 5.01e-01 | 79.2% | 54.3% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 66.0 | 4.37e-01 | 95.8% | 43.7% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 57.0 | 4.80e-01 | 81.2% | 47.0% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.76 | 58.0 | 4.50e-01 | 83.3% | 46.7% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.75 | 61.0 | 4.85e-01 | 93.8% | 74.5% |
| 4ksaA02 | 1.20.140.90 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain | 0.74 | 61.0 | 4.44e-01 | 93.8% | 36.5% |
| 1vw4L01 | 3.90.1030.10 | Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 | 0.74 | 66.0 | 4.74e-01 | 100.0% | 63.7% |
| 4cpgA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.74 | 62.0 | 5.63e-01 | 100.0% | 72.5% |
| 7nc3F01 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.73 | 59.0 | 4.57e-01 | 93.8% | 63.2% |
| 3k1hA00 | 3.30.1120.180 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 | 0.73 | 63.0 | 4.84e-01 | 100.0% | 73.9% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.72 | 62.0 | 4.18e-01 | 100.0% | 55.6% |
| 7p5hB03 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.72 | 52.0 | 4.29e-01 | 79.2% | 43.8% |
| 2g8lB01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.70 | 47.0 | 4.24e-01 | 70.8% | 61.2% |
| 2b3tB01 | 6.10.140.1980 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 57.0 | 5.19e-01 | 95.8% | 67.7% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.69 | 58.0 | 4.46e-01 | 95.8% | 59.8% |
| 1oisA01 | 1.10.10.41 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Yeast DNA topoisomerase - domain 1 | 0.69 | 56.0 | 4.52e-01 | 89.6% | 50.0% |
| 3ieeA02 | 1.20.58.820 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 | 0.69 | 57.0 | 4.53e-01 | 95.8% | 93.2% |
| 1euhA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.67 | 46.0 | 2.84e-01 | 70.8% | 52.6% |
| 4g10A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.67 | 55.0 | 4.06e-01 | 95.8% | 49.3% |
| 1hqoA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 55.0 | 4.08e-01 | 95.8% | 80.9% |
| 2ii2A04 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.65 | 53.0 | 4.61e-01 | 97.9% | 58.2% |
| 3b9qA01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.65 | 46.0 | 3.66e-01 | 72.9% | 43.8% |
| 1a59A02 | 1.10.230.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 | 0.64 | 43.0 | 3.38e-01 | 70.8% | 32.4% |
| 2mbgA01 | 1.10.555.10 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein | 0.63 | 55.0 | 3.65e-01 | 100.0% | 25.6% |
| 4od8D00 | 6.10.140.1880 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 46.0 | 4.61e-01 | 85.4% | 90.2% |
| 1ps9A02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.62 | 52.0 | 3.83e-01 | 100.0% | 49.7% |
| 1icrA00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.62 | 51.0 | 3.30e-01 | 91.7% | 50.0% |
| 2vx2G02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.61 | 45.0 | 4.38e-01 | 81.2% | 76.4% |
| 3rx6A00 | 1.20.58.1090 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer | 0.59 | 51.0 | 3.43e-01 | 100.0% | 72.2% |
| 1t98A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.57 | 48.0 | 4.01e-01 | 97.9% | 71.3% |
| 5tgtA02 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.57 | 48.0 | 3.66e-01 | 100.0% | 74.0% |
ECOD (44)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3909630 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.94 | 75.0 | 6.32e-01 | 85.4% | 56.0% |
| 5025186 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.93 | 72.0 | 5.63e-01 | 81.2% | 43.3% |
| 4182426 | 192.6.1.2 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATPD_C_fung | 0.93 | 71.0 | 7.17e-01 | 81.2% | 81.2% |
| 3738598 | 192.6.1.2 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATPD_C_fung | 0.92 | 71.0 | 7.68e-01 | 81.2% | 97.5% |
| 5027312 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.91 | 70.0 | 5.28e-01 | 81.2% | 37.9% |
| 3757869 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.91 | 69.0 | 5.39e-01 | 81.2% | 41.1% |
| 3855328 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.91 | 69.0 | 5.38e-01 | 81.2% | 41.1% |
| 3503536 | 3711.1.1.38 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › Patched | 0.91 | 67.0 | 5.35e-01 | 79.2% | 42.2% |
| 4884522 | 304.28.1.17 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sterol-sensing | 0.90 | 67.0 | 4.54e-01 | 79.2% | 24.8% |
| 4826095 | 5067.1.1.5 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing | 0.90 | 67.0 | 5.28e-01 | 79.2% | 41.9% |
| 4638770 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.89 | 72.0 | 5.74e-01 | 87.5% | 70.0% |
| 3361840 | 3796.1.1.0 ↗ | alpha arrays › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain | 0.87 | 64.0 | 6.92e-01 | 79.2% | 95.0% |
| 4015874 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.87 | 76.0 | 5.04e-01 | 95.8% | 82.3% |
| 3536346 | 109.4.1.910 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_MROH2B_C | 0.84 | 75.0 | 4.75e-01 | 100.0% | 32.5% |
| 3629293 | 109.4.1.1222 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_PSME4 | 0.84 | 71.0 | 4.51e-01 | 93.8% | 20.4% |
| 4063712 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.84 | 73.0 | 4.47e-01 | 97.9% | 18.6% |
| 5057476 | 2004.1.1.221 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › P-loop_TraG | 0.83 | 65.0 | 3.75e-01 | 83.3% | 25.1% |
| 3450780 | 109.4.1.293 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPP2R1A-like_HEAT | 0.82 | 69.0 | 4.08e-01 | 95.8% | 12.6% |
| 3807618 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.82 | 62.0 | 5.93e-01 | 81.2% | 70.9% |
| 3603633 | 3997.1.1.1 ↗ | alpha arrays › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › CobN-Mg_chel | 0.81 | 71.0 | 4.72e-01 | 100.0% | 39.5% |
| 3285819 | 101.1.2.92 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_11 | 0.81 | 69.0 | 4.93e-01 | 93.8% | 36.9% |
| 3284609 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.80 | 67.0 | 5.54e-01 | 93.8% | 83.5% |
| 3258522 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.79 | 61.0 | 5.55e-01 | 85.4% | 67.7% |
| None | — | 0.78 | 65.0 | 3.88e-01 | 93.8% | 13.8% | |
| 3959009 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.78 | 61.0 | 5.57e-01 | 87.5% | 64.6% |
| 3576327 | 6067.1.1.1 ↗ | alpha arrays › Dimerization domain of Sgt2 › Dimerization domain of Sgt2 › Dimerization domain of Sgt2 › SGTA_dimer | 0.77 | 67.0 | 5.86e-01 | 100.0% | 68.0% |
| 3613191 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.77 | 66.0 | 4.09e-01 | 100.0% | 18.2% |
| 3281023 | 628.1.1.1 ↗ | alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD | 0.77 | 64.0 | 4.52e-01 | 95.8% | 59.3% |
| 3717006 | 206.1.1.66 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › CLU | 0.73 | 64.0 | 3.80e-01 | 100.0% | 39.4% |
| 5077460 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.73 | 60.0 | 5.47e-01 | 95.8% | 89.7% |
| 4991191 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.71 | 61.0 | 3.83e-01 | 100.0% | 43.6% |
| 3742038 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.70 | 62.0 | 3.98e-01 | 100.0% | 54.7% |
| 3552824 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.70 | 62.0 | 4.03e-01 | 100.0% | 52.9% |
| 3738395 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.69 | 61.0 | 3.89e-01 | 100.0% | 51.9% |
| 5052064 | 7579.1.1.6 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 | 0.69 | 55.0 | 3.46e-01 | 89.6% | 23.1% |
| 4999081 | 2002.1.1.57 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › URO-D | 0.62 | 53.0 | 3.15e-01 | 100.0% | 18.5% |
| 4230219 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.61 | 53.0 | 3.39e-01 | 100.0% | 45.9% |
| 4340554 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.60 | 54.0 | 3.37e-01 | 100.0% | 72.2% |
| 4533356 | 1128.1.1.2 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 | 0.59 | 50.0 | 4.16e-01 | 91.7% | 66.3% |
| 3330460 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.58 | 49.0 | 4.39e-01 | 91.7% | 80.0% |
| 4564092 | 101.8.1.1 ↗ | alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › tRNA-synt_1f,Anticodon_2 | 0.58 | 52.0 | 3.22e-01 | 97.9% | 49.6% |
| 4381762 | 558.1.1.26 ↗ | alpha duplicates or obligate multimers › Lis-homology dimerization domain › Lis-homology dimerization domain › Lis-homology dimerization domain › WD40 | 0.56 | 47.0 | 2.73e-01 | 100.0% | 10.1% |
| 2095477 | 1170.1.2.2 ↗ | beta barrels › IL8-related › IL8-related › chemokine-related domain in glycoprotein L (gL) | 0.53 | 42.0 | 3.23e-01 | 100.0% | 53.2% |
| 4384626 | 101.8.1.2 ↗ | alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 | 0.52 | 43.0 | 3.09e-01 | 100.0% | 49.4% |
D2
medium
residues 56-106_165-184
Domain cluster:
representative
CATH (73)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2h1yA02 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.73 | 42.0 | 4.24e-01 | 71.8% | 57.1% |
| 2lrrA00 | 3.30.1370.50 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain | 0.72 | 45.0 | 4.55e-01 | 77.5% | 64.3% |
| 3hz7A00 | 3.30.110.40 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › TusA-like domain | 0.70 | 45.0 | 4.47e-01 | 71.8% | 63.0% |
| 2kl8A00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.69 | 47.0 | 4.45e-01 | 71.8% | 58.8% |
| 3evzA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.69 | 45.0 | 3.47e-01 | 77.5% | 28.9% |
| 1b24A01 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.68 | 47.0 | 4.26e-01 | 71.8% | 54.7% |
| 3onqA02 | 3.30.70.2730 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 45.0 | 4.38e-01 | 71.8% | 60.5% |
| 1j27A00 | 3.30.70.1120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TT1725-like | 0.68 | 46.0 | 4.22e-01 | 71.8% | 64.3% |
| 4gczB03 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.68 | 46.0 | 3.58e-01 | 71.8% | 45.3% |
| 6lpnA04 | 3.30.70.2740 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 46.0 | 4.20e-01 | 71.8% | 55.8% |
| 7qh2C03 | 3.30.70.2740 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 46.0 | 4.49e-01 | 71.8% | 73.1% |
| 1j4wA01 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.67 | 46.0 | 4.54e-01 | 71.8% | 74.3% |
| 3fgvA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 46.0 | 4.21e-01 | 71.8% | 60.2% |
| 3rrkA03 | 3.30.70.2750 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 43.0 | 4.34e-01 | 71.8% | 64.9% |
| 3pm9A04 | 3.30.70.2740 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 48.0 | 4.51e-01 | 78.9% | 63.2% |
| 2if1A00 | 3.30.780.10 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain | 0.66 | 42.0 | 3.51e-01 | 71.8% | 36.5% |
| 3i3wA04 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.66 | 45.0 | 4.42e-01 | 71.8% | 75.3% |
| 2vs7A02 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.65 | 43.0 | 4.26e-01 | 71.8% | 62.8% |
| 3aqoA01 | 3.30.70.3400 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 44.0 | 4.30e-01 | 71.8% | 67.5% |
| 2l3mA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 42.0 | 4.23e-01 | 71.8% | 66.2% |
| 1yz7A02 | 3.30.70.1130 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha | 0.64 | 44.0 | 4.12e-01 | 71.8% | 63.3% |
| 2lu1A00 | 3.30.70.2370 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 44.0 | 4.13e-01 | 71.8% | 71.9% |
| 3c1mA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.64 | 44.0 | 3.36e-01 | 71.8% | 31.7% |
| 2anrA02 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.64 | 44.0 | 4.35e-01 | 71.8% | 69.3% |
| 3zxoA00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.64 | 45.0 | 3.80e-01 | 74.6% | 45.6% |
| 1o51A00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 43.0 | 4.09e-01 | 71.8% | 65.2% |
| 1x60A01 | 3.30.70.1070 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat | 0.63 | 43.0 | 4.36e-01 | 71.8% | 72.2% |
| 3gkuA03 | 3.30.1370.50 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain | 0.63 | 41.0 | 4.14e-01 | 77.5% | 66.2% |
| 3d7aA01 | 3.30.1440.10 | Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 | 0.62 | 40.0 | 3.28e-01 | 71.8% | 34.6% |
| 2f1fA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.62 | 42.0 | 4.10e-01 | 71.8% | 63.3% |
| 3tqeA02 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.62 | 39.0 | 3.93e-01 | 71.8% | 61.6% |
| 3mahA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.62 | 38.0 | 3.82e-01 | 71.8% | 60.0% |
| 2h00B00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.62 | 40.0 | 2.95e-01 | 77.5% | 22.9% |
| 3im9A02 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.62 | 40.0 | 3.99e-01 | 70.4% | 63.5% |
| 4dzrA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.61 | 45.0 | 3.44e-01 | 78.9% | 86.5% |
| 1wjwA01 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.61 | 41.0 | 3.95e-01 | 71.8% | 77.6% |
| 2yweA03 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.61 | 42.0 | 4.04e-01 | 71.8% | 62.2% |
| 3ofgB00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.60 | 41.0 | 3.90e-01 | 71.8% | 67.8% |
| 1vigA00 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.60 | 41.0 | 4.16e-01 | 71.8% | 73.2% |
| 2gukA00 | 3.30.2190.10 | Alpha Beta › 2-Layer Sandwich › PG1857-like › PG1857-like | 0.60 | 44.0 | 3.84e-01 | 91.5% | 50.5% |
| 5w2fA01 | 3.30.780.10 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain | 0.59 | 40.0 | 3.80e-01 | 71.8% | 58.1% |
| 2mzwA01 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.59 | 38.0 | 3.81e-01 | 71.8% | 63.2% |
| 4aukA01 | 3.30.70.2810 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 39.0 | 3.86e-01 | 70.4% | 63.3% |
| 3kxyJ00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.58 | 40.0 | 3.35e-01 | 71.8% | 48.1% |
| 1x0pA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 50.0 | 4.57e-01 | 97.2% | 95.8% |
| 2uvaG03 | 3.30.70.3320 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 40.0 | 3.52e-01 | 71.8% | 63.0% |
| 2cveA02 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 36.0 | 3.73e-01 | 71.8% | 65.2% |
| 1tuwA00 | 3.30.70.1090 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. | 0.58 | 39.0 | 3.56e-01 | 71.8% | 53.8% |
| 1apsA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 50.0 | 4.52e-01 | 97.2% | 93.9% |
| 1itpA00 | 3.30.70.80 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 | 0.58 | 38.0 | 3.77e-01 | 71.8% | 62.3% |
| 7n0eB02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.58 | 40.0 | 3.37e-01 | 71.8% | 42.6% |
| 4oj3B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 49.0 | 4.49e-01 | 95.8% | 92.6% |
| 4petA01 | 3.40.190.170 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 | 0.57 | 49.0 | 3.58e-01 | 100.0% | 61.4% |
| 6u26A01 | 3.30.70.80 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 | 0.57 | 39.0 | 3.70e-01 | 71.8% | 61.4% |
| 1urrA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 48.0 | 4.42e-01 | 97.2% | 93.8% |
| 1dq3A04 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.56 | 42.0 | 3.67e-01 | 83.1% | 72.8% |
| 1darA05 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 39.0 | 3.72e-01 | 74.6% | 83.9% |
| 1s28A00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.55 | 37.0 | 3.14e-01 | 77.5% | 38.5% |
| 4rl1A02 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.55 | 36.0 | 3.63e-01 | 71.8% | 66.2% |
| 3trgA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 47.0 | 4.33e-01 | 95.8% | 92.6% |
| 5bmnA04 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.55 | 37.0 | 3.62e-01 | 71.8% | 78.3% |
| 4dmzA02 | 3.30.70.2880 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 44.0 | 3.60e-01 | 90.1% | 91.2% |
| 5o5cB02 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.55 | 37.0 | 3.17e-01 | 71.8% | 78.9% |
| 1dfuP00 | 2.40.240.10 | Mainly Beta › Beta Barrel › Ribosomal Protein L25; Chain P › Ribosomal Protein L25; Chain P | 0.55 | 45.0 | 4.21e-01 | 95.8% | 91.5% |
| 3vtiA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 47.0 | 4.30e-01 | 100.0% | 96.9% |
| 2abyA00 | 3.30.70.1980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF09406, DUF2004 | 0.53 | 43.0 | 3.68e-01 | 91.5% | 81.1% |
| 3cx5A01 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.53 | 47.0 | 3.39e-01 | 100.0% | 47.5% |
| 1ayeA01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.52 | 34.0 | 3.11e-01 | 71.8% | 46.5% |
| 7y8uF01 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.52 | 46.0 | 3.40e-01 | 100.0% | 49.5% |
| 3c18A03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 38.0 | 4.17e-01 | 77.5% | 98.2% |
| 3go9A02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.51 | 45.0 | 3.22e-01 | 100.0% | 48.8% |
| 4dzdA01 | 3.30.70.1200 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 1 | 0.50 | 34.0 | 3.49e-01 | 71.8% | 74.3% |
| 4ezeB00 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.50 | 41.0 | 2.77e-01 | 91.5% | 85.1% |
ECOD (93)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3218069 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.74 | 50.0 | 5.25e-01 | 70.4% | 80.0% |
| 3411905 | 327.11.2.20 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › BICC1_KH | 0.74 | 48.0 | 4.98e-01 | 71.8% | 72.3% |
| 5075416 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.72 | 49.0 | 4.22e-01 | 71.8% | 45.5% |
| 5009157 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.70 | 48.0 | 4.14e-01 | 71.8% | 45.5% |
| 4973817 | 304.126.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C | 0.70 | 48.0 | 4.33e-01 | 71.8% | 52.6% |
| 4078982 | 3019.1.1.1 ↗ | beta sandwiches › gp11/flagellar cap protein FliD insertion domain › gp11/flagellar cap protein FliD insertion domain › gp11/flagellar cap protein FliD insertion domain › Flagellin_IN | 0.69 | 48.0 | 3.94e-01 | 71.8% | 60.8% |
| 4941328 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.69 | 47.0 | 4.01e-01 | 71.8% | 68.3% |
| 3386960 | 304.14.1.1 ↗ | a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR | 0.69 | 48.0 | 4.96e-01 | 71.8% | 80.0% |
| 4937053 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.69 | 47.0 | 4.19e-01 | 71.8% | 50.0% |
| 3200904 | 304.162.1.2 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › FLAD1_M | 0.68 | 47.0 | 4.64e-01 | 71.8% | 69.3% |
| 3950275 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.68 | 44.0 | 4.16e-01 | 71.8% | 54.1% |
| 3521944 | 327.11.2.26 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_N4BP1_1st | 0.68 | 46.0 | 4.68e-01 | 70.4% | 71.4% |
| 3772566 | 327.11.2.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 | 0.68 | 47.0 | 4.61e-01 | 71.8% | 69.3% |
| 3195325 | 304.162.1.2 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › FLAD1_M | 0.68 | 46.0 | 4.50e-01 | 71.8% | 65.0% |
| 5022357 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.68 | 42.0 | 4.53e-01 | 71.8% | 75.0% |
| 3820397 | 320.1.1.1 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H | 0.67 | 45.0 | 4.10e-01 | 77.5% | 51.6% |
| 3317423 | 387.1.5.15 ↗ | few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like › SLR1-BP | 0.67 | 44.0 | 5.06e-01 | 71.8% | 96.0% |
| 4130677 | 304.162.1.1 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH | 0.67 | 44.0 | 4.46e-01 | 71.8% | 68.6% |
| 4982458 | 304.162.1.2 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › FLAD1_M | 0.67 | 45.0 | 4.56e-01 | 71.8% | 71.4% |
| 1211839 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.66 | 46.0 | 4.16e-01 | 71.8% | 54.2% |
| 4998391 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.66 | 44.0 | 4.13e-01 | 71.8% | 54.4% |
| 3628330 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.66 | 45.0 | 4.31e-01 | 71.8% | 62.4% |
| 3307802 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.66 | 42.0 | 3.99e-01 | 71.8% | 52.3% |
| 5582 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.66 | 42.0 | 3.51e-01 | 71.8% | 36.5% |
| 3724442 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.66 | 45.0 | 4.59e-01 | 71.8% | 77.1% |
| 3327785 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.66 | 45.0 | 4.00e-01 | 71.8% | 49.5% |
| 4130731 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.65 | 45.0 | 3.55e-01 | 71.8% | 40.0% |
| 4264245 | 331.2.1.1 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV | 0.65 | 45.0 | 4.17e-01 | 71.8% | 63.3% |
| 3789491 | 304.162.1.0 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain | 0.65 | 44.0 | 4.25e-01 | 71.8% | 67.1% |
| 4257164 | 331.2.1.1 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV | 0.65 | 44.0 | 4.32e-01 | 71.8% | 71.2% |
| 3672141 | 304.162.1.0 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain | 0.65 | 44.0 | 4.50e-01 | 71.8% | 72.9% |
| 3641694 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.65 | 42.0 | 3.71e-01 | 71.8% | 43.8% |
| 3593859 | 306.3.1.0 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like | 0.65 | 42.0 | 3.76e-01 | 71.8% | 44.8% |
| 4020561 | 306.3.1.0 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like | 0.65 | 42.0 | 3.82e-01 | 71.8% | 47.0% |
| 3519958 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.65 | 45.0 | 4.53e-01 | 71.8% | 78.6% |
| 3940990 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.65 | 44.0 | 4.43e-01 | 71.8% | 71.4% |
| 4464001 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.65 | 42.0 | 3.66e-01 | 71.8% | 41.7% |
| 4026919 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.64 | 42.0 | 3.69e-01 | 71.8% | 43.6% |
| 4937023 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.64 | 43.0 | 3.91e-01 | 71.8% | 49.0% |
| 3609340 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.64 | 42.0 | 3.85e-01 | 71.8% | 50.5% |
| 5037293 | 304.126.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C | 0.64 | 42.0 | 4.23e-01 | 71.8% | 68.6% |
| 4068249 | 331.2.1.1 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV | 0.64 | 44.0 | 4.24e-01 | 71.8% | 73.8% |
| 3698585 | 320.1.1.1 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H | 0.63 | 46.0 | 4.42e-01 | 81.7% | 67.5% |
| 4933638 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.63 | 48.0 | 3.84e-01 | 81.7% | 62.9% |
| 4992865 | 304.126.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C | 0.63 | 41.0 | 3.94e-01 | 71.8% | 56.5% |
| 4999898 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.63 | 41.0 | 3.83e-01 | 71.8% | 52.2% |
| 4297401 | 304.110.1.0 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like | 0.63 | 51.0 | 4.94e-01 | 88.7% | 100.0% |
| 3388222 | 331.2.1.1 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV | 0.63 | 43.0 | 4.24e-01 | 71.8% | 73.3% |
| 3283943 | 304.8.1.80 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › DUF6196 | 0.62 | 43.0 | 4.33e-01 | 71.8% | 78.6% |
| 3651874 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.62 | 41.0 | 3.71e-01 | 71.8% | 48.0% |
| 4240253 | 331.2.1.1 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV | 0.62 | 43.0 | 4.27e-01 | 71.8% | 74.0% |
| 3757456 | 327.11.2.4 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › MOEP19 | 0.62 | 42.0 | 4.39e-01 | 71.8% | 83.1% |
| 4134039 | 304.162.1.1 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH | 0.62 | 40.0 | 4.02e-01 | 71.8% | 64.0% |
| 3839430 | 331.2.1.1 ↗ | a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV | 0.61 | 42.0 | 4.17e-01 | 71.8% | 73.3% |
| 4225320 | 306.3.1.4 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › PFF1_C | 0.61 | 42.0 | 3.71e-01 | 71.8% | 46.7% |
| 3300216 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.61 | 40.0 | 3.61e-01 | 71.8% | 45.7% |
| 4262988 | 304.162.1.0 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain | 0.61 | 42.0 | 3.99e-01 | 71.8% | 60.0% |
| 4995849 | 304.126.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C | 0.61 | 40.0 | 3.73e-01 | 71.8% | 53.3% |
| 5000786 | 3501.1.1.1 ↗ | a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 | 0.61 | 42.0 | 4.05e-01 | 71.8% | 67.5% |
| 3745974 | 304.9.1.40 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › BRAP2 | 0.61 | 42.0 | 3.49e-01 | 71.8% | 59.2% |
| 5056226 | 304.126.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C | 0.61 | 39.0 | 4.01e-01 | 71.8% | 67.1% |
| 5023724 | 2.1.1.95 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Lig_C | 0.61 | 44.0 | 3.59e-01 | 78.9% | 40.7% |
| 5620 | 320.3.1.1 ↗ | a+b two layers › R3H domain-like › PG1857-like › PG1857-like › DUF2023 | 0.60 | 44.0 | 3.84e-01 | 91.5% | 50.5% |
| 1904137 | 2003.1.5.165 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11, Methyltransf_23 | 0.60 | 44.0 | 3.07e-01 | 78.9% | 34.2% |
| 1036625 | 3122.1.1.1 ↗ | a+b complex topology › MESD › MESD › MESD › Mesd | 0.60 | 41.0 | 4.02e-01 | 71.8% | 65.4% |
| 3740868 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.60 | 41.0 | 3.98e-01 | 71.8% | 66.3% |
| 5230 | 304.7.1.0 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors | 0.60 | 39.0 | 3.90e-01 | 71.8% | 65.3% |
| 3271101 | 3501.1.1.1 ↗ | a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 | 0.59 | 40.0 | 3.94e-01 | 71.8% | 65.0% |
| 3241661 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.59 | 43.0 | 4.30e-01 | 78.9% | 76.0% |
| 4941622 | 305.1.1.1 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L | 0.59 | 41.0 | 3.81e-01 | 73.2% | 60.0% |
| 3958050 | 304.110.1.0 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like | 0.58 | 49.0 | 4.61e-01 | 95.8% | 97.8% |
| 4156195 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.57 | 49.0 | 4.41e-01 | 95.8% | 86.9% |
| 4318283 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.57 | 49.0 | 4.54e-01 | 95.8% | 96.7% |
| 3410799 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.57 | 49.0 | 4.35e-01 | 97.2% | 86.7% |
| 5042490 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.57 | 50.0 | 4.48e-01 | 100.0% | 96.0% |
| 4553581 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.57 | 48.0 | 4.49e-01 | 97.2% | 96.8% |
| 4979822 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.57 | 48.0 | 4.34e-01 | 95.8% | 87.0% |
| 4946776 | 304.110.1.0 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like | 0.57 | 48.0 | 4.47e-01 | 95.8% | 97.8% |
| 4654074 | 304.5.1.0 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like | 0.57 | 41.0 | 3.83e-01 | 77.5% | 84.4% |
| 4339550 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.56 | 47.0 | 4.33e-01 | 94.4% | 98.9% |
| 4108216 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.56 | 48.0 | 4.50e-01 | 97.2% | 98.9% |
| 4068447 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.56 | 48.0 | 4.38e-01 | 95.8% | 95.8% |
| 4211715 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.56 | 48.0 | 4.27e-01 | 97.2% | 85.7% |
| 3267490 | 101.1.2.24 ↗ | alpha arrays › HTH › HTH › winged helix domain › MAGE | 0.55 | 44.0 | 3.10e-01 | 87.3% | 73.6% |
| 4992607 | 304.110.1.1 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase | 0.55 | 47.0 | 4.16e-01 | 97.2% | 88.6% |
| 4169525 | 304.110.1.4 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › UPF0176_N | 0.53 | 45.0 | 4.18e-01 | 97.2% | 91.6% |
| 3204194 | 101.1.2.86 ↗ | alpha arrays › HTH › HTH › winged helix domain › SMC_Nse1 | 0.53 | 38.0 | 3.49e-01 | 76.1% | 77.9% |
| 4202669 | 304.110.1.4 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › UPF0176_N | 0.53 | 44.0 | 4.08e-01 | 97.2% | 91.6% |
| 4976949 | 304.126.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C | 0.52 | 42.0 | 4.00e-01 | 91.5% | 100.0% |
| 3655839 | 207.11.1.1 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD | 0.52 | 36.0 | 2.72e-01 | 71.8% | 29.4% |
| 5035849 | 3501.1.1.0 ↗ | a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 | 0.52 | 34.0 | 3.40e-01 | 71.8% | 62.0% |
| 5074162 | 304.126.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C | 0.52 | 41.0 | 3.82e-01 | 90.1% | 92.6% |
| 4945774 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.50 | 37.0 | 3.31e-01 | 78.9% | 56.0% |
D3
medium
residues 107-164_185-219
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vi0A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 47.0 | 3.96e-01 | 79.6% | 86.2% |
| 3b9wA00 | 1.10.3430.10 | Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains | 0.60 | 53.0 | 3.59e-01 | 100.0% | 46.1% |
| 3ccyA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 44.0 | 3.71e-01 | 79.6% | 86.4% |
| 2fx0A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 37.0 | 3.28e-01 | 78.5% | 48.5% |
| 7e84A03 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 44.0 | 4.02e-01 | 88.2% | 66.7% |
| 1cpcA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.51 | 43.0 | 3.66e-01 | 94.6% | 63.6% |
| 3khkB01 | 1.20.1260.30 | Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain | 0.51 | 41.0 | 3.55e-01 | 91.4% | 100.0% |
| 1u61A00 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.50 | 43.0 | 3.88e-01 | 94.6% | 84.3% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.50 | 35.0 | 3.03e-01 | 74.2% | 46.6% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5025454 | 5081.1.1.0 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like | 0.69 | 58.0 | 4.60e-01 | 89.2% | 66.1% |
| 3281672 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.61 | 48.0 | 3.73e-01 | 94.6% | 39.5% |
| 4674000 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.60 | 49.0 | 4.29e-01 | 88.2% | 66.9% |
| 3573621 | 5059.1.1.8 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA | 0.59 | 50.0 | 4.23e-01 | 95.7% | 80.0% |
| 3433766 | 5050.1.1.28 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 | 0.58 | 50.0 | 3.68e-01 | 96.8% | 38.2% |
| 3258297 | 141.1.1.0 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases | 0.57 | 50.0 | 3.83e-01 | 98.9% | 90.6% |
| 3483292 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 45.0 | 3.52e-01 | 97.8% | 41.0% |
| 3663318 | 5050.1.1.28 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 | 0.56 | 47.0 | 3.47e-01 | 94.6% | 36.5% |
| 3571298 | 5059.1.1.8 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA | 0.56 | 48.0 | 3.95e-01 | 96.8% | 75.4% |
| 3933280 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.53 | 46.0 | 3.71e-01 | 98.9% | 86.7% |
| 3936681 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.53 | 45.0 | 3.42e-01 | 95.7% | 75.1% |
| 4025614 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.53 | 45.0 | 3.66e-01 | 95.7% | 97.8% |
| 4237660 | 1008.1.1.0 ↗ | alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain | 0.52 | 39.0 | 3.56e-01 | 78.5% | 65.8% |