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IMGVR_UViG_3300029851_000210-3300029851-Ga0245290_10011530
Arc-VirIMGVR_UViG_3300029851_000210-3300029851-Ga0245290_10011530
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-55
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01757.29 best | Acyl_transf_3 | 34.8 | 1.30e-08 | 90.9% | 16.3% |
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2cazD00 | 6.10.140.820 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 58.0 | 5.69e-01 | 90.9% | 90.0% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 57.0 | 5.57e-01 | 90.9% | 85.5% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 60.0 | 5.50e-01 | 96.4% | 82.2% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 61.0 | 4.67e-01 | 96.4% | 42.2% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.69 | 56.0 | 4.06e-01 | 89.1% | 34.2% |
| 1k90B03 | 1.20.140.60 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.69 | 55.0 | 4.35e-01 | 89.1% | 48.7% |
| 4y9jA01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 60.0 | 4.42e-01 | 100.0% | 47.0% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.68 | 60.0 | 4.73e-01 | 98.2% | 52.7% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.68 | 59.0 | 4.60e-01 | 98.2% | 46.3% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 55.0 | 4.54e-01 | 96.4% | 75.5% |
| 2kwhA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 51.0 | 5.13e-01 | 89.1% | 92.9% |
| 4nphA02 | 1.20.1270.330 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 52.0 | 4.74e-01 | 90.9% | 87.8% |
| 7blz201 | 1.10.3460.10 | Mainly Alpha › Orthogonal Bundle › Chlorophyll a-b binding protein › Chlorophyll a/b binding protein domain | 0.63 | 52.0 | 3.80e-01 | 89.1% | 87.1% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.63 | 54.0 | 4.75e-01 | 96.4% | 84.1% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 53.0 | 4.85e-01 | 98.2% | 75.0% |
| 1exzB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.62 | 48.0 | 3.75e-01 | 90.9% | 35.7% |
| 3ic9A02 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.53 | 47.0 | 4.33e-01 | 98.2% | 82.9% |
| 3lphC00 | 6.10.140.630 | Special › Helix non-globular › Helix Hairpins › | 0.50 | 38.0 | 3.79e-01 | 98.2% | 86.2% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3585791 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.76 | 65.0 | 5.82e-01 | 94.5% | 78.7% |
| 4013639 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.73 | 62.0 | 4.57e-01 | 94.5% | 45.0% |
| 4013609 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 51.0 | 3.20e-01 | 80.0% | 20.7% |
| 3595683 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.68 | 57.0 | 3.97e-01 | 94.5% | 43.2% |
| 5035050 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.67 | 57.0 | 4.76e-01 | 94.5% | 55.1% |
| 3642682 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.67 | 58.0 | 4.64e-01 | 100.0% | 53.9% |
| 3274005 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 54.0 | 3.22e-01 | 94.5% | 16.9% |
| 3566072 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.62 | 54.0 | 5.01e-01 | 96.4% | 78.6% |
| 3880178 | 192.8.1.92 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › CUPID | 0.62 | 49.0 | 4.47e-01 | 92.7% | 85.0% |
| 3507551 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.61 | 49.0 | 4.35e-01 | 100.0% | 60.0% |
| 3195005 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 49.0 | 4.31e-01 | 94.5% | 81.1% |
| 3413284 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 50.0 | 2.98e-01 | 96.4% | 19.2% |
D2
medium
residues 56-181
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01757.29 best | Acyl_transf_3 | 41.8 | 1.00e-10 | 99.2% | 39.9% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ciuA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 44.0 | 3.83e-01 | 94.4% | 80.2% |
D3
medium
residues 182-278
Domain cluster:
representative
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 43.0 | 4.89e-01 | 93.8% | 80.8% |
| 7odyC01 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.71 | 44.0 | 4.54e-01 | 82.5% | 66.3% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.68 | 47.0 | 4.46e-01 | 71.1% | 77.0% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 34.0 | 4.10e-01 | 77.3% | 73.0% |
| 3fhnA01 | 6.10.280.210 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A | 0.67 | 42.0 | 3.43e-01 | 84.5% | 33.7% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.65 | 44.0 | 3.70e-01 | 81.4% | 41.6% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.64 | 44.0 | 3.79e-01 | 71.1% | 100.0% |
| 3mekA04 | 1.25.40.970 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.64 | 36.0 | 3.90e-01 | 89.7% | 66.3% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 40.0 | 4.08e-01 | 76.3% | 63.9% |
| 2a3qA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.63 | 49.0 | 4.66e-01 | 82.5% | 74.3% |
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.63 | 43.0 | 4.01e-01 | 70.1% | 97.5% |
| 2q5zB00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.62 | 46.0 | 4.67e-01 | 82.5% | 79.8% |
| 3lnnB03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.62 | 41.0 | 4.81e-01 | 75.3% | 98.5% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 53.0 | 5.47e-01 | 93.8% | 97.8% |
| 3ipiA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.61 | 47.0 | 3.36e-01 | 85.6% | 29.1% |
| 2zdiB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 44.0 | 4.34e-01 | 78.4% | 84.9% |
| 5nl6A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 47.0 | 4.58e-01 | 85.6% | 79.6% |
| 2kq9A00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.59 | 42.0 | 3.97e-01 | 73.2% | 67.0% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.59 | 42.0 | 2.95e-01 | 75.3% | 23.9% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.58 | 41.0 | 4.50e-01 | 73.2% | 92.4% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 38.0 | 3.64e-01 | 77.3% | 55.1% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.58 | 44.0 | 4.62e-01 | 79.4% | 93.1% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 46.0 | 4.52e-01 | 84.5% | 89.2% |
| 1rfyB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.58 | 47.0 | 4.98e-01 | 88.7% | 97.7% |
| 5ha6B00 | 1.10.287.210 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 42.0 | 4.62e-01 | 84.5% | 93.7% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.57 | 44.0 | 4.80e-01 | 81.4% | 98.8% |
| 4p3fA00 | 1.10.3450.40 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › Signal recognition particle, SRP68 subunit, RNA-binding domain | 0.57 | 50.0 | 3.99e-01 | 97.9% | 48.7% |
| 3terA00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 40.0 | 3.81e-01 | 75.3% | 71.4% |
| 4od4A01 | 1.10.357.140 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase | 0.56 | 41.0 | 3.48e-01 | 75.3% | 81.4% |
| 1ux5A03 | 1.20.58.2220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain | 0.56 | 44.0 | 3.30e-01 | 83.5% | 68.2% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.56 | 44.0 | 4.68e-01 | 84.5% | 95.3% |
| 1wncB00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.56 | 38.0 | 4.12e-01 | 74.2% | 84.0% |
| 1e6dM01 | 1.20.85.10 | Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like | 0.55 | 46.0 | 3.98e-01 | 86.6% | 63.6% |
| 1u00A02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 37.0 | 3.81e-01 | 71.1% | 68.8% |
| 3x29A00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.55 | 44.0 | 3.69e-01 | 85.6% | 51.2% |
| 5cbgA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 43.0 | 4.24e-01 | 82.5% | 84.3% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.54 | 45.0 | 4.26e-01 | 95.9% | 75.0% |
| 3ousA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 43.0 | 4.62e-01 | 86.6% | 100.0% |
| 3purA03 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 39.0 | 3.79e-01 | 94.8% | 67.3% |
| 1grlB01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.54 | 41.0 | 3.18e-01 | 84.5% | 62.3% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 43.0 | 3.90e-01 | 89.7% | 69.9% |
| 5jazA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.53 | 32.0 | 3.35e-01 | 72.2% | 63.7% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 41.0 | 3.92e-01 | 86.6% | 81.7% |
| 7b00A01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.53 | 45.0 | 3.00e-01 | 100.0% | 97.8% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 40.0 | 4.23e-01 | 81.4% | 100.0% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.52 | 42.0 | 3.56e-01 | 91.8% | 51.1% |
| 2gtaA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.52 | 41.0 | 4.19e-01 | 99.0% | 88.7% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.52 | 46.0 | 4.03e-01 | 99.0% | 91.6% |
| 2b7mA00 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.50 | 44.0 | 2.82e-01 | 100.0% | 34.7% |
| 2fbnA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.50 | 41.0 | 3.56e-01 | 89.7% | 60.8% |
ECOD (56)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5040013 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.66 | 45.0 | 4.69e-01 | 75.3% | 75.6% |
| 4940500 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.66 | 39.0 | 3.64e-01 | 70.1% | 49.6% |
| 4349607 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.64 | 41.0 | 3.98e-01 | 78.4% | 57.3% |
| 3710139 | 604.13.1.0 ↗ | alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like | 0.64 | 41.0 | 3.80e-01 | 92.8% | 50.4% |
| 5029796 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.64 | 45.0 | 4.17e-01 | 75.3% | 59.2% |
| 4886422 | 3660.1.1.1 ↗ | alpha bundles › Protein-export membrane protein secG › Protein-export membrane protein secG › Protein-export membrane protein secG › SecG | 0.63 | 46.0 | 5.16e-01 | 82.5% | 97.3% |
| 5018039 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.62 | 45.0 | 4.28e-01 | 78.4% | 64.3% |
| 3279027 | 150.8.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE | 0.62 | 41.0 | 3.41e-01 | 76.3% | 37.7% |
| 3220072 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 49.0 | 4.66e-01 | 85.6% | 77.4% |
| 4354474 | 101.1.2.598 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, POLR3C_WHD | 0.61 | 47.0 | 3.01e-01 | 81.4% | 65.8% |
| 3600562 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 51.0 | 4.27e-01 | 91.8% | 59.4% |
| 3595767 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 55.0 | 3.62e-01 | 100.0% | 95.0% |
| 4499889 | 192.24.1.1 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RPC3_helical | 0.60 | 44.0 | 4.53e-01 | 81.4% | 79.6% |
| 4016292 | 192.2.1.18 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING | 0.60 | 44.0 | 3.95e-01 | 78.4% | 54.8% |
| 3646792 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.60 | 51.0 | 3.96e-01 | 90.7% | 73.7% |
| 3582451 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.60 | 52.0 | 5.31e-01 | 94.8% | 100.0% |
| 4096103 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.60 | 46.0 | 4.06e-01 | 80.4% | 71.1% |
| 2325490 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 47.0 | 4.55e-01 | 85.6% | 77.7% |
| 3927319 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.59 | 45.0 | 4.47e-01 | 78.4% | 97.0% |
| 3741196 | 6091.1.1.0 ↗ | alpha bundles › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase | 0.59 | 41.0 | 4.14e-01 | 73.2% | 70.0% |
| 3881420 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.59 | 45.0 | 3.96e-01 | 79.4% | 100.0% |
| 3235363 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.59 | 44.0 | 3.35e-01 | 77.3% | 44.1% |
| 3268501 | 141.1.1.3 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA | 0.59 | 47.0 | 3.28e-01 | 85.6% | 27.8% |
| 3625262 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.59 | 46.0 | 3.81e-01 | 82.5% | 47.1% |
| 3476594 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.59 | 47.0 | 4.51e-01 | 84.5% | 79.1% |
| 3729479 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 44.0 | 3.61e-01 | 85.6% | 45.5% |
| 4942625 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.58 | 35.0 | 3.83e-01 | 70.1% | 72.5% |
| 3777607 | 633.23.1.1 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin | 0.58 | 46.0 | 3.73e-01 | 85.6% | 45.9% |
| 4023215 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.58 | 48.0 | 3.13e-01 | 90.7% | 26.4% |
| 3197471 | 603.1.1.179 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › TPR_VPS8_2 | 0.58 | 50.0 | 3.88e-01 | 95.9% | 77.7% |
| 3178900 | 192.2.1.30 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Uds1 | 0.58 | 45.0 | 3.96e-01 | 83.5% | 64.8% |
| 4453815 | 192.12.1.1 ↗ | alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM › Prok-TraM | 0.57 | 47.0 | 4.82e-01 | 89.7% | 96.8% |
| 3309008 | 375.1.1.246 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rad50_zn_hook | 0.57 | 42.0 | 4.14e-01 | 77.3% | 98.1% |
| 4463557 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.57 | 42.0 | 4.32e-01 | 77.3% | 81.1% |
| 3718745 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.57 | 43.0 | 3.82e-01 | 79.4% | 80.7% |
| 3739409 | 3285.1.1.0 ↗ | alpha duplicates or obligate multimers › Alix V domain › Alix V domain › Alix V domain | 0.57 | 42.0 | 3.35e-01 | 78.4% | 47.5% |
| 3791157 | 5001.1.1.10 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Ceramidase | 0.57 | 41.0 | 2.98e-01 | 79.4% | 25.6% |
| 4630084 | 192.10.1.0 ↗ | alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain | 0.57 | 42.0 | 4.40e-01 | 82.5% | 85.6% |
| 3536912 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.57 | 48.0 | 3.42e-01 | 90.7% | 75.7% |
| 3182290 | 174.1.1.4 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4267 | 0.57 | 40.0 | 3.56e-01 | 72.2% | 58.5% |
| 3828954 | 3324.1.1.1 ↗ | extended segments › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › MTR4_beta-barrel | 0.57 | 43.0 | 4.12e-01 | 81.4% | 70.0% |
| 3946052 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.56 | 44.0 | 2.97e-01 | 82.5% | 61.1% |
| 3389151 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 50.0 | 2.95e-01 | 96.9% | 26.8% |
| 3900518 | 109.4.1.374 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FANCI_S4 | 0.56 | 47.0 | 3.61e-01 | 95.9% | 70.2% |
| 3719904 | 148.1.3.13 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 | 0.56 | 44.0 | 2.96e-01 | 83.5% | 23.2% |
| 3235794 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 45.0 | 3.98e-01 | 87.6% | 91.4% |
| 3883667 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 43.0 | 4.23e-01 | 83.5% | 90.5% |
| 3179076 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.55 | 45.0 | 4.01e-01 | 85.6% | 90.8% |
| 4965830 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.55 | 45.0 | 3.45e-01 | 90.7% | 49.6% |
| 3244401 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.55 | 45.0 | 4.28e-01 | 87.6% | 80.0% |
| 3703032 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.54 | 41.0 | 3.84e-01 | 82.5% | 79.2% |
| 2756826 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.53 | 43.0 | 4.12e-01 | 89.7% | 78.3% |
| 4443506 | 101.1.2.517 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD | 0.53 | 44.0 | 2.89e-01 | 89.7% | 39.6% |
| 3576275 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.53 | 45.0 | 4.15e-01 | 95.9% | 78.5% |
| 3693258 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.53 | 41.0 | 4.01e-01 | 84.5% | 89.1% |
| 4022292 | 4207.1.1.35 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Med14 | 0.51 | 37.0 | 3.24e-01 | 76.3% | 54.8% |
D4
medium
residues 279-354
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.72 | 50.0 | 4.57e-01 | 72.4% | 56.9% |
| 3bg2A03 | 1.10.3410.10 | Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain | 0.70 | 51.0 | 4.76e-01 | 77.6% | 75.0% |
| 3hpcX00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.64 | 48.0 | 3.88e-01 | 81.6% | 85.2% |
| 4jgiA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.63 | 42.0 | 4.20e-01 | 73.7% | 66.3% |
| 3umbA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.63 | 46.0 | 4.55e-01 | 80.3% | 73.4% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.59 | 45.0 | 3.79e-01 | 81.6% | 94.4% |
| 4mk3A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 40.0 | 3.52e-01 | 71.1% | 72.2% |
| 2hxoA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 42.0 | 3.46e-01 | 77.6% | 95.1% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 46.0 | 3.27e-01 | 85.5% | 79.0% |
| 2lklA01 | 1.10.1900.40 | Mainly Alpha › Orthogonal Bundle › c-terminal domain of poly(a) binding protein › Acidic terminal segments, variant surface antigen of PfEMP1 | 0.51 | 38.0 | 3.87e-01 | 94.7% | 86.1% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.51 | 37.0 | 3.52e-01 | 75.0% | 85.1% |
| 3wd6A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 37.0 | 3.16e-01 | 76.3% | 79.7% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5075900 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.72 | 52.0 | 3.85e-01 | 76.3% | 35.9% |
| 5001129 | 3542.1.1.1 ↗ | alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin | 0.70 | 55.0 | 3.58e-01 | 82.9% | 23.2% |
| 3290367 | 3470.1.1.0 ↗ | extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain | 0.70 | 55.0 | 5.90e-01 | 88.2% | 98.5% |
| 5063587 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.69 | 56.0 | 5.42e-01 | 88.2% | 97.6% |
| 4103905 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.69 | 56.0 | 3.91e-01 | 89.5% | 30.4% |
| 4353218 | 605.1.1.167 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PKK | 0.69 | 48.0 | 4.88e-01 | 72.4% | 76.0% |
| 5034026 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.69 | 48.0 | 4.37e-01 | 73.7% | 58.1% |
| 3270180 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.68 | 52.0 | 4.93e-01 | 81.6% | 78.9% |
| 4977468 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.67 | 47.0 | 4.46e-01 | 73.7% | 64.4% |
| 4964132 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.66 | 45.0 | 4.10e-01 | 72.4% | 57.1% |
| 4959134 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.65 | 50.0 | 3.72e-01 | 81.6% | 67.4% |
| 4964983 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.64 | 45.0 | 4.29e-01 | 73.7% | 63.3% |
| 4217669 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.63 | 51.0 | 3.65e-01 | 90.8% | 29.6% |
| 4149728 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.62 | 46.0 | 4.60e-01 | 81.6% | 90.0% |
| 3386452 | 5050.1.1.21 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FTR1 | 0.62 | 44.0 | 3.60e-01 | 75.0% | 62.1% |
| 4520394 | 5063.1.1.1 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › PSI_PSAK | 0.62 | 48.0 | 5.01e-01 | 85.5% | 92.8% |
| 4101335 | 2006.1.4.8 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_5 | 0.61 | 49.0 | 3.47e-01 | 85.5% | 56.9% |
| 4933532 | 604.39.1.26 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › 5TM-5TMR_LYT | 0.61 | 46.0 | 3.59e-01 | 82.9% | 42.8% |
| 3838282 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.60 | 46.0 | 4.37e-01 | 93.4% | 68.4% |
| 5053903 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.57 | 44.0 | 3.89e-01 | 86.8% | 72.5% |
| 3588334 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.56 | 44.0 | 3.84e-01 | 88.2% | 53.6% |