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IMGVR_UViG_3300029928_000198-3300029928-Ga0116643_100008164
Arc-VirIMGVR_UViG_3300029928_000198-3300029928-Ga0116643_100008164
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-129
Domain cluster:
rep: putative_DNA_polymerase_epsilon_subunit__YP_009052389__Aureococcus_anophagefferens_virus__1474867__D2-144
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2p1jA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.84 | 71.0 | 6.91e-01 | 100.0% | 81.2% |
| 1wljA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.82 | 64.0 | 5.74e-01 | 100.0% | 61.3% |
| 2qxfA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.80 | 75.0 | 6.38e-01 | 100.0% | 65.6% |
| 1j54A00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.80 | 72.0 | 6.41e-01 | 100.0% | 70.1% |
| 1j9aA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.78 | 73.0 | 6.33e-01 | 100.0% | 68.5% |
| 5dk5A01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.74 | 70.0 | 5.94e-01 | 100.0% | 65.3% |
| 4qozB02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.74 | 70.0 | 5.70e-01 | 100.0% | 58.6% |
| 7wrnA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.74 | 69.0 | 5.88e-01 | 100.0% | 66.2% |
| 2xriA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.73 | 68.0 | 5.74e-01 | 100.0% | 62.4% |
| 7essA01 | 3.30.420.140 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain | 0.66 | 44.0 | 4.38e-01 | 100.0% | 65.2% |
| 1krlA00 | 6.20.50.130 | Special › Other non-globular › N-terminal domain of TfIIb › | 0.64 | 22.0 | 3.77e-01 | 86.7% | 88.6% |
| 1vhxB00 | 3.30.420.140 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain | 0.61 | 42.0 | 4.17e-01 | 100.0% | 65.9% |
| 2gv9A03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.61 | 57.0 | 4.67e-01 | 100.0% | 68.3% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5052601 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.92 | 79.0 | 6.72e-01 | 100.0% | 59.8% |
| 4586442 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.86 | 72.0 | 5.89e-01 | 100.0% | 51.4% |
| 5062283 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.83 | 73.0 | 6.11e-01 | 100.0% | 57.8% |
| 3963965 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.83 | 73.0 | 6.48e-01 | 100.0% | 68.0% |
| 3945113 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.82 | 72.0 | 6.29e-01 | 100.0% | 65.0% |
| 3822649 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.81 | 72.0 | 6.00e-01 | 100.0% | 57.4% |
| 4102293 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.79 | 67.0 | 5.76e-01 | 100.0% | 60.0% |
| 2499661 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.78 | 72.0 | 6.35e-01 | 100.0% | 69.6% |
| 3923319 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.74 | 70.0 | 5.57e-01 | 100.0% | 56.6% |
| 4505558 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.74 | 69.0 | 5.81e-01 | 100.0% | 63.9% |
| 3520911 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.73 | 69.0 | 6.51e-01 | 100.0% | 91.3% |
| 3489491 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.73 | 69.0 | 5.45e-01 | 100.0% | 54.7% |
| 3528742 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.73 | 68.0 | 5.66e-01 | 100.0% | 60.9% |
| 3555211 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.73 | 69.0 | 5.76e-01 | 100.0% | 63.9% |
| 3733253 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.73 | 68.0 | 5.37e-01 | 100.0% | 53.2% |
| 3175633 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.65 | 54.0 | 4.56e-01 | 100.0% | 54.6% |
| 4307499 | 2484.1.1.40 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX | 0.64 | 44.0 | 4.21e-01 | 100.0% | 61.4% |
| 4949167 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.64 | 59.0 | 4.78e-01 | 99.2% | 63.9% |
| 4118739 | 2484.1.1.40 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX | 0.64 | 44.0 | 4.19e-01 | 100.0% | 61.4% |
| 4358798 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.64 | 28.0 | 3.58e-01 | 76.6% | 69.3% |
| 3931129 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.63 | 43.0 | 3.28e-01 | 100.0% | 30.7% |
| 3327473 | 2484.1.1.40 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX | 0.62 | 44.0 | 4.64e-01 | 99.2% | 82.5% |
| 3797547 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.54 | 40.0 | 3.75e-01 | 100.0% | 63.2% |
| 4014784 | 9.14.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › Uncharacterized protein YLR301W › Uncharacterized protein YLR301W › HRI1 | 0.51 | 30.0 | 3.37e-01 | 100.0% | 75.5% |
D2
high
residues 130-224
Domain cluster:
representative
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.64 | 41.0 | 3.93e-01 | 95.8% | 56.0% |
| 2ex3B02 | 1.20.1270.230 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › DNA terminal protein Gp3, priming domain | 0.64 | 35.0 | 3.76e-01 | 89.5% | 61.7% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.62 | 39.0 | 4.29e-01 | 97.9% | 76.9% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.60 | 34.0 | 3.63e-01 | 92.6% | 64.2% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.59 | 38.0 | 3.78e-01 | 95.8% | 63.0% |
| 1x42A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.57 | 35.0 | 3.67e-01 | 70.5% | 68.7% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.57 | 31.0 | 3.00e-01 | 87.4% | 47.2% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 36.0 | 3.17e-01 | 95.8% | 47.5% |
| 2vzcB00 | 1.10.418.10 | Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain | 0.53 | 41.0 | 3.81e-01 | 84.2% | 78.6% |
| 3k8pC01 | 1.20.58.1440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 32.0 | 3.15e-01 | 82.1% | 54.3% |
| 2q9rA01 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.53 | 43.0 | 3.46e-01 | 89.5% | 91.8% |
| 2r18A02 | 1.10.8.880 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Birnavirus VP3 protein, domain 2 | 0.53 | 29.0 | 3.43e-01 | 88.4% | 83.1% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.52 | 38.0 | 3.30e-01 | 78.9% | 66.2% |
| 1t5oA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.52 | 46.0 | 4.05e-01 | 98.9% | 96.5% |
| 1cp9B03 | 1.10.1400.10 | Mainly Alpha › Orthogonal Bundle › Penicillin amidase (Acylase) alpha subunit, N-terminal domain › Aminohydrolase, alpha-helical knob region | 0.51 | 41.0 | 3.56e-01 | 91.6% | 71.4% |
| 2gsvA00 | 6.10.140.40 | Special › Helix non-globular › Helix Hairpins › | 0.50 | 30.0 | 3.54e-01 | 81.1% | 85.1% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.50 | 32.0 | 3.60e-01 | 96.8% | 83.8% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.50 | 33.0 | 3.05e-01 | 93.7% | 52.0% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.50 | 47.0 | 3.62e-01 | 100.0% | 63.2% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4016253 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.71 | 37.0 | 3.59e-01 | 77.9% | 45.7% |
| 4024049 | 1134.1.1.0 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain | 0.70 | 36.0 | 4.02e-01 | 91.6% | 64.0% |
| 4025636 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.68 | 38.0 | 3.19e-01 | 81.1% | 33.5% |
| 5019483 | 148.1.3.20 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_2 | 0.63 | 53.0 | 5.15e-01 | 90.5% | 95.2% |
| 3574413 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.63 | 33.0 | 3.40e-01 | 86.3% | 52.2% |
| 5061420 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.61 | 47.0 | 3.45e-01 | 81.1% | 60.8% |
| 3936678 | 164.1.1.0 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II | 0.61 | 29.0 | 3.20e-01 | 86.3% | 53.8% |
| 3642152 | 102.5.1.9 ↗ | alpha arrays › HhH/H2TH › SAM-like subdomain in Sec63-like proteins › SAM-like subdomain in Sec63-like proteins › DUF7898 | 0.59 | 40.0 | 4.00e-01 | 83.2% | 67.0% |
| 4942614 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.58 | 41.0 | 3.46e-01 | 74.7% | 75.1% |
| 3680378 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.57 | 32.0 | 3.15e-01 | 88.4% | 49.0% |
| 3463721 | 5077.1.1.0 ↗ | extended segments › Chlorophyll a-b binding protein › Chlorophyll a-b binding protein › Chlorophyll a-b binding protein | 0.56 | 38.0 | 3.56e-01 | 87.4% | 56.5% |
| 3706707 | 592.2.1.0 ↗ | alpha arrays › PWI domain-like › YugE-like › YugE-like | 0.56 | 32.0 | 3.27e-01 | 83.2% | 55.8% |
| 4617970 | 377.1.1.11 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › RecO_C | 0.56 | 44.0 | 3.82e-01 | 90.5% | 86.1% |
| 3500048 | 206.1.1.17 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Kdo | 0.55 | 43.0 | 3.01e-01 | 84.2% | 58.7% |
| 4934652 | 2004.1.1.76 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 | 0.55 | 49.0 | 3.28e-01 | 100.0% | 38.7% |
| 3632779 | 145.1.1.0 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain | 0.54 | 38.0 | 3.51e-01 | 92.6% | 54.6% |
| 5054405 | 606.1.1.1 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop | 0.53 | 39.0 | 3.82e-01 | 82.1% | 71.0% |
| 3167298 | 3711.1.1.0 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein | 0.53 | 37.0 | 3.62e-01 | 93.7% | 65.7% |
| 4977094 | 606.1.1.1 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop | 0.52 | 40.0 | 3.56e-01 | 80.0% | 65.4% |
| 5002671 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.51 | 36.0 | 2.99e-01 | 93.7% | 42.5% |
| 1699723 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.50 | 29.0 | 3.06e-01 | 83.2% | 61.9% |