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IMGVR_UViG_3300029928_000218-3300029928-Ga0116643_100021641
Arc-VirIMGVR_UViG_3300029928_000218-3300029928-Ga0116643_100021641
Identity
- Kingdom:
- archaea
Quality
69.5
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 381-443
Domain cluster:
representative
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3p5pA03 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.69 | 59.0 | 3.83e-01 | 100.0% | 71.1% |
| 5nx5B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.67 | 59.0 | 3.83e-01 | 100.0% | 44.9% |
| 4s1pA00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.66 | 49.0 | 3.53e-01 | 79.4% | 95.1% |
| 4rkrB01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.66 | 55.0 | 4.41e-01 | 95.2% | 82.3% |
| 3keyA01 | 1.10.10.1080 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain | 0.65 | 45.0 | 4.06e-01 | 73.0% | 56.3% |
| 1l0oC00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 35.0 | 3.70e-01 | 77.8% | 59.6% |
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.62 | 50.0 | 4.14e-01 | 95.2% | 77.4% |
| 7watB02 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.61 | 51.0 | 3.36e-01 | 100.0% | 53.5% |
| 3it4B01 | 3.30.2330.10 | Alpha Beta › 2-Layer Sandwich › arginine biosynthesis bifunctional protein fold › arginine biosynthesis bifunctional protein suprefamily | 0.61 | 52.0 | 4.85e-01 | 96.8% | 86.1% |
| 2yqzA02 | 1.10.8.900 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.60 | 41.0 | 4.00e-01 | 85.7% | 64.7% |
| 2mf4A01 | 1.10.1200.10 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like | 0.60 | 41.0 | 3.76e-01 | 93.7% | 54.9% |
| 2w4sA00 | 1.10.10.1440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PHAX RNA-binding domain | 0.59 | 42.0 | 3.78e-01 | 95.2% | 54.7% |
| 2kg7B00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.59 | 38.0 | 3.24e-01 | 84.1% | 42.3% |
| 1br2A03 | 1.20.120.720 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Myosin VI head, motor domain, U50 subdomain | 0.58 | 49.0 | 4.24e-01 | 96.8% | 61.1% |
| 6pe0E01 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.57 | 43.0 | 4.58e-01 | 96.8% | 100.0% |
| 1ah5A03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.57 | 46.0 | 4.17e-01 | 88.9% | 89.5% |
| 1khvA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.57 | 45.0 | 3.50e-01 | 84.1% | 46.9% |
| 4jkzA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 45.0 | 3.30e-01 | 92.1% | 36.3% |
| 1t9kA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.55 | 41.0 | 3.29e-01 | 84.1% | 92.9% |
| 2ah5A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.54 | 36.0 | 3.62e-01 | 87.3% | 67.7% |
| 4a17O01 | 1.10.1650.10 | Mainly Alpha › Orthogonal Bundle › 50s Ribosomal Protein L19e, Chain O, domain 1 › | 0.54 | 41.0 | 4.29e-01 | 85.7% | 96.4% |
| 2o5rA04 | 1.10.8.70 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutamate-tRNA synthetase, class I, anticodon-binding domain 1 | 0.54 | 38.0 | 4.06e-01 | 79.4% | 100.0% |
| 3cmnA01 | 1.20.150.30 | Mainly Alpha › Up-down Bundle › Lysin › Zincin-like metallopeptidase, N-terminal domain | 0.53 | 42.0 | 3.66e-01 | 96.8% | 99.1% |
| 3q9oA02 | 3.90.1350.10 | Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain | 0.53 | 39.0 | 2.83e-01 | 77.8% | 58.7% |
| 3dciA00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.53 | 43.0 | 3.06e-01 | 93.7% | 93.2% |
| 2g7gA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 42.0 | 3.08e-01 | 95.2% | 49.7% |
| 1k8kF00 | 3.30.1460.20 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.51 | 45.0 | 3.31e-01 | 98.4% | 72.5% |
| 4emeA01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.51 | 43.0 | 2.78e-01 | 100.0% | 47.2% |
| 3d8lA00 | 1.10.8.940 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein, phage p2 ORF12 | 0.50 | 40.0 | 3.61e-01 | 90.5% | 75.8% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3787849 | 103.1.1.57 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › GDH2_N | 0.80 | 72.0 | 6.27e-01 | 100.0% | 73.7% |
| 3713829 | 101.1.2.127 ↗ | alpha arrays › HTH › HTH › winged helix domain › Cullin_Nedd8 | 0.75 | 43.0 | 3.64e-01 | 93.7% | 35.0% |
| 3951251 | 305.1.1.7 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › GDH_ACT2 | 0.74 | 64.0 | 4.59e-01 | 95.2% | 34.7% |
| 4583308 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.73 | 63.0 | 4.53e-01 | 95.2% | 34.7% |
| 4612240 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.71 | 42.0 | 3.01e-01 | 98.4% | 21.7% |
| 3807848 | 103.1.1.34 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › PIR2-like_helical | 0.71 | 64.0 | 5.78e-01 | 100.0% | 75.3% |
| 4635810 | 148.1.3.173 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_RFC1 | 0.68 | 55.0 | 5.52e-01 | 100.0% | 89.2% |
| 3635200 | 130.1.1.0 ↗ | alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif | 0.66 | 36.0 | 3.83e-01 | 81.0% | 60.0% |
| 4039677 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.64 | 41.0 | 2.81e-01 | 98.4% | 20.0% |
| 4341780 | 4957.1.1.0 ↗ | a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit | 0.61 | 50.0 | 4.99e-01 | 95.2% | 92.3% |
| 3990640 | 148.1.3.19 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 | 0.60 | 49.0 | 4.63e-01 | 96.8% | 74.7% |
| 4993602 | 632.23.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I | 0.60 | 50.0 | 5.10e-01 | 92.1% | 96.8% |
| 4304389 | 5086.1.1.119 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › RRG1_C | 0.60 | 42.0 | 2.91e-01 | 74.6% | 22.3% |
| 3828844 | 109.1.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C | 0.60 | 55.0 | 4.08e-01 | 100.0% | 47.7% |
| 4485396 | 1037.1.1.1 ↗ | alpha bundles › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › LGT | 0.59 | 49.0 | 3.26e-01 | 96.8% | 32.8% |
| 4675816 | 3754.1.1.2 ↗ | alpha bundles › Bacterial cell wall synthesis membrane enzyme MraY-related › Bacterial cell wall synthesis membrane enzyme MraY-related › Bacterial cell wall synthesis membrane enzyme MraY-related › Glycos_transf_4,MraY_sig1 | 0.58 | 51.0 | 3.27e-01 | 100.0% | 88.4% |
| 4273496 | 4953.1.1.4 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ASL_C2 | 0.58 | 46.0 | 4.33e-01 | 92.1% | 71.2% |
| 3596357 | 327.11.2.3 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_6 | 0.57 | 46.0 | 3.86e-01 | 95.2% | 52.5% |
| 3887909 | 148.1.3.5 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Pol_alpha_B_N | 0.57 | 43.0 | 4.20e-01 | 90.5% | 78.7% |
| 4971418 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.56 | 49.0 | 3.66e-01 | 98.4% | 54.3% |
| 4524125 | 1037.1.1.1 ↗ | alpha bundles › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › LGT | 0.55 | 45.0 | 3.07e-01 | 92.1% | 38.4% |
| 3943827 | 3754.1.1.1 ↗ | alpha bundles › Bacterial cell wall synthesis membrane enzyme MraY-related › Bacterial cell wall synthesis membrane enzyme MraY-related › Bacterial cell wall synthesis membrane enzyme MraY-related › Glycos_transf_4 | 0.55 | 45.0 | 2.94e-01 | 98.4% | 56.7% |
| 4680076 | 3754.1.1.1 ↗ | alpha bundles › Bacterial cell wall synthesis membrane enzyme MraY-related › Bacterial cell wall synthesis membrane enzyme MraY-related › Bacterial cell wall synthesis membrane enzyme MraY-related › Glycos_transf_4 | 0.55 | 47.0 | 3.05e-01 | 100.0% | 56.2% |
| 5043228 | 7597.1.1.1 ↗ | a/b three-layered sandwiches › Endolysin C-terminal domain › Endolysin C-terminal domain › Endolysin C-terminal domain › CW_binding_2 | 0.53 | 40.0 | 3.53e-01 | 84.1% | 89.0% |
| 4936946 | 1134.1.2.0 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Archaeal C-Ala helical domain | 0.52 | 42.0 | 4.37e-01 | 93.7% | 95.0% |
| 3733527 | 109.38.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Telomere length regulation protein TEL2 › Telomere length regulation protein TEL2 › Telomere_reg-2 | 0.52 | 48.0 | 2.68e-01 | 100.0% | 28.9% |
| 3507982 | 632.2.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains | 0.52 | 43.0 | 3.73e-01 | 96.8% | 97.1% |
| 3741278 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.51 | 46.0 | 3.19e-01 | 100.0% | 82.9% |
| 3468645 | 4177.1.1.11 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF632 | 0.51 | 46.0 | 3.04e-01 | 100.0% | 81.6% |
| 3556512 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.50 | 42.0 | 3.50e-01 | 96.8% | 64.3% |
D2
high
residues 461-560
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2py5A05 | 4.10.80.20 | Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › DNA polymerase; domain 5 | 0.58 | 22.0 | 3.40e-01 | 91.0% | 93.3% |
| 4iqzA02 | 2.40.50.100 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain | 0.56 | 39.0 | 3.91e-01 | 72.0% | 85.0% |
| 3h41A02 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.54 | 36.0 | 4.07e-01 | 94.0% | 100.0% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3396896 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.63 | 37.0 | 4.15e-01 | 89.0% | 76.0% |
| 3276661 | 4004.1.1.6 ↗ | beta sandwiches › NAD kinase beta sandwich domain-like › NAD kinase beta sandwich domain-like › NAD kinase beta sandwich domain-like › Pacs-1 | 0.54 | 41.0 | 3.55e-01 | 82.0% | 87.3% |
D3
high
residues 586-640
D4
medium
residues 87-189_360-380
Domain cluster:
representative
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.69 | 62.0 | 6.04e-01 | 100.0% | 90.2% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.66 | 41.0 | 4.93e-01 | 83.1% | 98.7% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.66 | 49.0 | 5.30e-01 | 100.0% | 94.1% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.64 | 37.0 | 3.75e-01 | 86.3% | 56.2% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.63 | 52.0 | 5.40e-01 | 100.0% | 97.3% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 35.0 | 4.40e-01 | 73.4% | 93.1% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.62 | 46.0 | 4.91e-01 | 100.0% | 88.8% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.61 | 48.0 | 4.73e-01 | 100.0% | 76.3% |
| 3edvA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 47.0 | 4.12e-01 | 100.0% | 54.6% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.60 | 38.0 | 4.32e-01 | 80.6% | 88.5% |
| 7zo9A01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.59 | 52.0 | 3.91e-01 | 96.8% | 45.7% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 45.0 | 3.91e-01 | 100.0% | 50.5% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.59 | 38.0 | 4.56e-01 | 82.3% | 100.0% |
| 2ieqA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.59 | 36.0 | 4.10e-01 | 76.6% | 84.1% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.58 | 35.0 | 4.31e-01 | 83.1% | 100.0% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.57 | 36.0 | 4.27e-01 | 80.6% | 97.5% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 43.0 | 4.56e-01 | 99.2% | 90.0% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.57 | 41.0 | 3.96e-01 | 76.6% | 65.7% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.57 | 38.0 | 3.93e-01 | 100.0% | 72.4% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.56 | 42.0 | 4.05e-01 | 99.2% | 67.1% |
| 3fhnA04 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.56 | 41.0 | 4.08e-01 | 100.0% | 72.5% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.56 | 39.0 | 3.93e-01 | 72.6% | 69.2% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 39.0 | 3.19e-01 | 71.0% | 63.8% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 43.0 | 4.72e-01 | 100.0% | 100.0% |
| 2eh3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 35.0 | 3.58e-01 | 97.6% | 63.9% |
| 4nuuB02 | 1.20.58.830 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 48.0 | 4.88e-01 | 99.2% | 96.7% |
| 1gxyA00 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.55 | 33.0 | 2.74e-01 | 85.5% | 32.3% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.55 | 34.0 | 4.15e-01 | 85.5% | 97.5% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 44.0 | 4.52e-01 | 100.0% | 88.3% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.55 | 36.0 | 4.09e-01 | 89.5% | 94.2% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 34.0 | 3.24e-01 | 71.0% | 52.4% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.55 | 36.0 | 3.43e-01 | 97.6% | 54.7% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.54 | 34.0 | 4.07e-01 | 83.9% | 100.0% |
| 4i1eA03 | 1.25.10.30 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain | 0.54 | 42.0 | 4.06e-01 | 100.0% | 72.7% |
| 2h5gB01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.54 | 41.0 | 3.25e-01 | 81.5% | 93.5% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.54 | 37.0 | 4.23e-01 | 70.2% | 96.6% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.53 | 32.0 | 3.70e-01 | 91.1% | 86.6% |
| 5x56B00 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.53 | 35.0 | 3.77e-01 | 96.0% | 78.1% |
| 3q23A08 | 1.20.140.110 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.53 | 38.0 | 3.62e-01 | 75.0% | 100.0% |
| 2or0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 38.0 | 3.39e-01 | 76.6% | 49.5% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.53 | 42.0 | 4.15e-01 | 92.7% | 79.7% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.53 | 36.0 | 4.00e-01 | 70.2% | 100.0% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 47.0 | 4.27e-01 | 100.0% | 72.8% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 40.0 | 3.32e-01 | 82.3% | 43.5% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.52 | 37.0 | 4.12e-01 | 87.1% | 96.8% |
| 3qowA01 | 1.10.260.60 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › | 0.52 | 27.0 | 2.74e-01 | 85.5% | 47.5% |
| 1fkmA02 | 1.10.472.80 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Ypt/Rab-GAP domain of gyp1p, domain 3 | 0.52 | 27.0 | 2.67e-01 | 79.0% | 43.0% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.51 | 36.0 | 3.89e-01 | 86.3% | 85.4% |
ECOD (56)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3478399 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.64 | 48.0 | 3.89e-01 | 80.6% | 42.2% |
| 1036846 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.64 | 52.0 | 5.27e-01 | 99.2% | 90.0% |
| 3276672 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.63 | 45.0 | 4.52e-01 | 96.8% | 71.5% |
| 3939419 | 601.1.2.96 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › MENTAL | 0.63 | 41.0 | 4.09e-01 | 96.8% | 63.1% |
| 4402843 | 604.1.1.20 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › AKNA | 0.62 | 50.0 | 5.16e-01 | 100.0% | 92.2% |
| 3221299 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.62 | 53.0 | 5.19e-01 | 100.0% | 86.7% |
| 3495807 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.61 | 43.0 | 3.39e-01 | 71.0% | 96.9% |
| 3630501 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.61 | 53.0 | 3.83e-01 | 94.4% | 38.9% |
| 3632025 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.61 | 36.0 | 3.56e-01 | 82.3% | 52.6% |
| 3201166 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.61 | 52.0 | 5.13e-01 | 100.0% | 86.7% |
| 3496446 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.59 | 46.0 | 4.27e-01 | 81.5% | 100.0% |
| 3990854 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.59 | 39.0 | 4.49e-01 | 81.5% | 94.4% |
| 3210941 | 109.4.1.371 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RTP1_C1 | 0.59 | 43.0 | 2.95e-01 | 99.2% | 23.3% |
| 3912535 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.59 | 49.0 | 4.19e-01 | 99.2% | 56.9% |
| 3614798 | 207.1.1.45 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_4,LRR_8 | 0.58 | 51.0 | 3.05e-01 | 96.8% | 35.7% |
| 3718745 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.57 | 51.0 | 4.96e-01 | 100.0% | 98.6% |
| 3315414 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.57 | 46.0 | 4.13e-01 | 87.9% | 86.1% |
| 4235156 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.57 | 40.0 | 4.13e-01 | 76.6% | 75.0% |
| 5046834 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.56 | 43.0 | 3.60e-01 | 100.0% | 46.0% |
| 3816971 | 3755.3.1.285 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A | 0.56 | 43.0 | 3.89e-01 | 80.6% | 83.5% |
| 3915380 | 192.5.1.25 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › PTHB1_hp | 0.56 | 35.0 | 4.00e-01 | 85.5% | 85.6% |
| 3623410 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.56 | 47.0 | 3.16e-01 | 93.5% | 44.3% |
| 4024597 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 39.0 | 3.68e-01 | 72.6% | 96.0% |
| 3702176 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.55 | 48.0 | 4.64e-01 | 100.0% | 85.7% |
| 4526671 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.55 | 48.0 | 3.87e-01 | 100.0% | 48.4% |
| 3931441 | 3835.1.1.0 ↗ | alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein | 0.54 | 49.0 | 4.06e-01 | 99.2% | 95.8% |
| 4137553 | 109.62.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain › AFF4_CHD | 0.54 | 43.0 | 3.57e-01 | 91.9% | 48.6% |
| 3801787 | 604.5.1.39 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PF26581 | 0.53 | 48.0 | 4.72e-01 | 100.0% | 92.6% |
| 3613649 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.53 | 47.0 | 4.05e-01 | 99.2% | 94.0% |
| 4629029 | 3285.1.1.1 ↗ | alpha duplicates or obligate multimers › Alix V domain › Alix V domain › Alix V domain › ALIX_LYPXL_bnd | 0.53 | 41.0 | 3.60e-01 | 82.3% | 66.8% |
| 3954410 | 304.28.2.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB TolC docking domain | 0.53 | 41.0 | 3.25e-01 | 82.3% | 85.8% |
| 4941837 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.53 | 39.0 | 3.86e-01 | 95.2% | 73.1% |
| 5056066 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 45.0 | 3.78e-01 | 92.7% | 81.4% |
| 4024356 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.53 | 46.0 | 4.29e-01 | 99.2% | 86.9% |
| 4962299 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 44.0 | 4.10e-01 | 100.0% | 73.5% |
| 2756825 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.52 | 42.0 | 4.19e-01 | 100.0% | 82.3% |
| 3827214 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.52 | 46.0 | 4.39e-01 | 100.0% | 81.4% |
| 3999487 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 45.0 | 4.54e-01 | 96.0% | 92.0% |
| 3729699 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.52 | 45.0 | 3.60e-01 | 99.2% | 57.9% |
| 3552989 | 604.8.1.1 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Smac_DIABLO | 0.52 | 48.0 | 4.20e-01 | 100.0% | 67.9% |
| 3997722 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.52 | 47.0 | 3.82e-01 | 100.0% | 51.7% |
| 3988781 | 604.6.1.63 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF3169 | 0.52 | 43.0 | 4.22e-01 | 100.0% | 82.2% |
| 3397081 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.52 | 47.0 | 4.40e-01 | 100.0% | 81.9% |
| 3238550 | 3939.1.1.161 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › Mitofilin | 0.52 | 46.0 | 4.33e-01 | 100.0% | 79.4% |
| 3244591 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.52 | 40.0 | 3.72e-01 | 83.1% | 70.6% |
| 3896730 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 44.0 | 4.31e-01 | 93.5% | 92.6% |
| 4998866 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.51 | 45.0 | 3.92e-01 | 99.2% | 78.5% |
| 3960600 | 3812.1.1.0 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE | 0.51 | 44.0 | 4.24e-01 | 95.2% | 95.8% |
| 3821321 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.51 | 36.0 | 3.46e-01 | 72.6% | 100.0% |
| 3852296 | 3755.3.1.123 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin | 0.51 | 40.0 | 3.58e-01 | 83.1% | 65.1% |
| 3887441 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 45.0 | 3.79e-01 | 97.6% | 77.6% |
| 3245682 | 601.1.3.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_middle | 0.51 | 35.0 | 3.29e-01 | 100.0% | 55.0% |
| 5030938 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.51 | 42.0 | 3.93e-01 | 87.9% | 73.3% |
| 4324499 | 3755.1.1.3 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › SPAM | 0.51 | 38.0 | 3.65e-01 | 81.5% | 67.6% |
| 3793986 | 604.7.1.7 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › Mitofilin | 0.50 | 45.0 | 4.39e-01 | 100.0% | 93.3% |
| 4205503 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.50 | 40.0 | 3.44e-01 | 83.9% | 100.0% |
D5
medium
residues 190-359
Domain cluster:
representative