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IMGVR_UViG_3300029937_000683-3300029937-Ga0119934_10002101
Arc-VirIMGVR_UViG_3300029937_000683-3300029937-Ga0119934_10002101
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 346-507
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF14579.13 best | HHH_6 | 38.7 | 1.30e-09 | 45.1% | 82.2% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4162931 | 102.1.1.28 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_6 | 0.76 | 55.0 | 5.49e-01 | 100.0% | 71.2% |
| 4288348 | 102.1.1.28 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_6 | 0.70 | 55.0 | 5.25e-01 | 100.0% | 71.4% |
| 3880840 | 375.1.1.246 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rad50_zn_hook | 0.54 | 28.0 | 3.41e-01 | 92.0% | 78.0% |
| 4019019 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 29.0 | 3.26e-01 | 91.4% | 66.7% |
| 3656888 | 3978.1.1.1 ↗ | alpha complex topology › Integral membrane Acyl-CoA desaturase › Integral membrane Acyl-CoA desaturase › Integral membrane Acyl-CoA desaturase › FA_desaturase | 0.51 | 39.0 | 3.08e-01 | 82.7% | 47.8% |
D2
high
residues 515-631
Domain cluster:
rep: OQ999172.1__WJZ23544.1__LIS04_116__00116__D6-94
D3
medium
residues 6-93
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07733.19 best | DNA_pol3_alpha | 53.1 | 5.20e-14 | 98.9% | 33.1% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1117589 | 316.1.1.17 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol3_alpha | 0.85 | 78.0 | 5.18e-01 | 100.0% | 27.6% |
| 4064450 | 316.1.1.17 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol3_alpha | 0.79 | 72.0 | 5.00e-01 | 100.0% | 32.2% |
| 3467157 | 109.4.1.1409 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_LIN_C, ARM_LIN_2nd | 0.52 | 38.0 | 2.64e-01 | 79.5% | 65.4% |
D4
medium
residues 97-188_276-345
Domain cluster:
rep: IMGVR_UViG_3300028048_000061-3300028048-Ga0256405_1000034382__D272-359_446-494
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF17657.7 best | DNA_pol3_finger | 48.8 | 7.30e-13 | 64.2% | 54.2% |
D5
medium
residues 189-275
Domain cluster:
rep: IMGVR_UViG_3300008004_000605-3300008004-Ga0100395_100035234__D688-761
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF17657.7 best | DNA_pol3_finger | 46.7 | 3.10e-12 | 77.0% | 39.8% |
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tfeA02 | 1.10.286.20 | Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › | 0.72 | 31.0 | 4.19e-01 | 79.3% | 77.8% |
| 2dbbB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.67 | 33.0 | 4.00e-01 | 90.8% | 72.7% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 48.0 | 4.63e-01 | 77.0% | 85.3% |
| 4a18Q01 | 1.10.10.1760 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L36 | 0.62 | 45.0 | 4.88e-01 | 100.0% | 97.1% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.62 | 46.0 | 3.75e-01 | 79.3% | 89.2% |
| 2ew2A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.60 | 49.0 | 4.20e-01 | 96.6% | 56.7% |
| 1bg6A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.60 | 41.0 | 3.48e-01 | 71.3% | 52.7% |
| 2o8xA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.60 | 35.0 | 3.99e-01 | 78.2% | 80.3% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.60 | 48.0 | 4.48e-01 | 96.6% | 69.1% |
| 1np7A02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 41.0 | 3.74e-01 | 93.1% | 52.1% |
| 2j5oA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.59 | 35.0 | 3.95e-01 | 96.6% | 78.5% |
| 3egoA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.59 | 44.0 | 4.00e-01 | 96.6% | 57.9% |
| 1s7oB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.59 | 34.0 | 3.27e-01 | 79.3% | 46.7% |
| 2da3A01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.59 | 33.0 | 4.08e-01 | 95.4% | 100.0% |
| 5fgmA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.59 | 34.0 | 3.82e-01 | 79.3% | 75.4% |
| 2go7A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.58 | 39.0 | 4.32e-01 | 78.2% | 89.6% |
| 1fc3B00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 43.0 | 4.14e-01 | 79.3% | 95.0% |
| 1on2A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 33.0 | 3.65e-01 | 73.6% | 68.1% |
| 3vfzB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 35.0 | 3.97e-01 | 79.3% | 82.5% |
| 2e19A01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.58 | 33.0 | 3.97e-01 | 88.5% | 100.0% |
| 2om6A02 | 1.10.150.400 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.57 | 39.0 | 4.11e-01 | 71.3% | 87.3% |
| 4ol9A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.56 | 42.0 | 3.76e-01 | 96.6% | 55.1% |
| 3hwrA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.56 | 42.0 | 3.76e-01 | 96.6% | 55.0% |
| 2w31A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 48.0 | 4.06e-01 | 98.9% | 88.2% |
| 3vsjA00 | 3.40.830.10 | Alpha Beta › 3-Layer(aba) Sandwich › Protocatechuate 4,5-dioxygenase; Chain B › LigB-like | 0.54 | 47.0 | 3.39e-01 | 98.9% | 97.0% |
| 1kblA04 | 3.20.20.60 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains | 0.54 | 44.0 | 2.99e-01 | 90.8% | 84.5% |
| 2rn7A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 35.0 | 3.82e-01 | 97.7% | 86.4% |
| 2f2cA02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.53 | 39.0 | 3.67e-01 | 79.3% | 63.2% |
| 4d3dB02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.52 | 40.0 | 3.61e-01 | 85.1% | 89.9% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.52 | 38.0 | 3.89e-01 | 97.7% | 81.2% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4522025 | 3584.1.1.1 ↗ | alpha arrays › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA_pol3_finger | 0.91 | 86.0 | 6.29e-01 | 100.0% | 42.4% |
| 4093848 | 3584.1.1.1 ↗ | alpha arrays › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA_pol3_finger | 0.91 | 86.0 | 6.26e-01 | 100.0% | 42.9% |
| 4411663 | 3584.1.1.1 ↗ | alpha arrays › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA_pol3_finger | 0.90 | 85.0 | 6.02e-01 | 100.0% | 39.6% |
| 4257959 | 3584.1.1.1 ↗ | alpha arrays › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA_pol3_finger | 0.81 | 74.0 | 5.65e-01 | 100.0% | 45.8% |
| 5056276 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.69 | 52.0 | 4.23e-01 | 79.3% | 65.6% |
| 5071140 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.62 | 44.0 | 3.72e-01 | 75.9% | 94.0% |
| 4020132 | 633.1.1.0 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain | 0.61 | 44.0 | 3.88e-01 | 77.0% | 54.1% |
| 3630157 | 109.3.1.26 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › SBF2 | 0.61 | 45.0 | 3.20e-01 | 95.4% | 26.7% |
| 3998879 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.59 | 48.0 | 4.39e-01 | 92.0% | 65.0% |
| 3740448 | 101.1.10.33 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Rrn7_cyclin_C | 0.58 | 38.0 | 3.91e-01 | 77.0% | 68.2% |
| 3864955 | 633.22.1.6 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) › TMD0_ABC | 0.55 | 41.0 | 3.33e-01 | 80.5% | 64.1% |
| None | — | 0.54 | 40.0 | 4.23e-01 | 78.2% | 90.0% | |
| 3735933 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.54 | 47.0 | 3.99e-01 | 97.7% | 95.9% |
| 4020872 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 47.0 | 3.91e-01 | 97.7% | 96.8% |
| 4500653 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.53 | 40.0 | 3.40e-01 | 81.6% | 76.7% |
| 3784055 | 192.24.1.0 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain | 0.53 | 37.0 | 3.29e-01 | 73.6% | 94.6% |
| 3606098 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 44.0 | 3.90e-01 | 94.3% | 65.4% |
| 3636505 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.51 | 46.0 | 3.23e-01 | 100.0% | 86.5% |