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IMGVR_UViG_3300031280_000001-3300031280-Ga0307428_100016453
Arc-VirIMGVR_UViG_3300031280_000001-3300031280-Ga0307428_100016453
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-32_146-211
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF23802.2 best | DUF7178 | 44.9 | 1.80e-11 | 68.0% | 31.1% |
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1xqoA01 | 1.10.1670.10 | Mainly Alpha › Orthogonal Bundle › Endonuclease Iii, domain 2 › Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) | 0.64 | 54.0 | 5.07e-01 | 91.8% | 82.2% |
| 2fsfB04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.52 | 35.0 | 2.77e-01 | 70.1% | 48.6% |
| 1fpqA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 37.0 | 3.47e-01 | 80.4% | 60.5% |
| 6t0bc01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.50 | 28.0 | 3.08e-01 | 72.2% | 66.7% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5055848 | 102.1.2.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase | 0.71 | 54.0 | 4.52e-01 | 80.4% | 98.8% |
| 3711217 | 101.7.1.0 ↗ | alpha arrays › HTH › DEK-C › DEK-C | 0.70 | 45.0 | 5.36e-01 | 78.4% | 98.5% |
| 5062751 | 102.1.2.5 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase › Ogg-HhH | 0.69 | 57.0 | 4.34e-01 | 88.7% | 98.2% |
| 4938192 | 102.1.2.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase | 0.68 | 52.0 | 4.29e-01 | 81.4% | 98.2% |
| 3660838 | 3121.1.1.12 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › GIL1_IRKI_C | 0.59 | 46.0 | 3.13e-01 | 83.5% | 41.0% |
| 4135696 | 3978.1.1.1 ↗ | alpha complex topology › Integral membrane Acyl-CoA desaturase › Integral membrane Acyl-CoA desaturase › Integral membrane Acyl-CoA desaturase › FA_desaturase | 0.57 | 44.0 | 3.12e-01 | 84.5% | 65.6% |
| 4942122 | 1079.1.1.12 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › GDT1 | 0.55 | 43.0 | 3.51e-01 | 83.5% | 82.1% |
| 3694505 | 3003.1.1.1 ↗ | a+b complex topology › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › MCM_N | 0.53 | 43.0 | 3.87e-01 | 89.7% | 97.9% |
| 3405141 | 7579.1.1.10 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Thioesterase | 0.51 | 39.0 | 2.84e-01 | 81.4% | 72.5% |
| 3968205 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.51 | 38.0 | 2.86e-01 | 78.4% | 75.8% |
| 3986141 | 7000.1.1.1 ↗ | alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › HTH_OrfB_IS605 | 0.51 | 37.0 | 3.77e-01 | 81.4% | 80.0% |
D2
high
residues 34-141
Domain cluster:
rep: NC_021347.1__YP_008061254.1__M176_gp217__00216__D410-460_636-679
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF23802.2 best | DUF7178 | 59.1 | 7.90e-16 | 100.0% | 46.6% |
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3od1A01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.68 | 50.0 | 3.56e-01 | 83.3% | 25.9% |
| 4uobA02 | 1.10.340.30 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2 | 0.67 | 60.0 | 5.71e-01 | 98.1% | 97.6% |
| 1sgmA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 39.0 | 3.27e-01 | 76.9% | 35.3% |
| 3ulkA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.65 | 47.0 | 3.50e-01 | 75.9% | 78.6% |
| 1xg7A02 | 1.10.340.30 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2 | 0.64 | 56.0 | 5.18e-01 | 100.0% | 91.6% |
| 2a6hF01 | 1.20.120.1810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 40.0 | 3.35e-01 | 79.6% | 37.7% |
| 3hi0A03 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.61 | 47.0 | 3.93e-01 | 85.2% | 74.6% |
| 4at7A01 | 1.10.1410.40 | Mainly Alpha › Orthogonal Bundle › Poly(a)-polymerase, middle domain › | 0.58 | 41.0 | 3.54e-01 | 74.1% | 75.3% |
| 3ucaA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.57 | 50.0 | 3.81e-01 | 100.0% | 97.4% |
| 4ldsA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.57 | 39.0 | 2.69e-01 | 72.2% | 80.0% |
| 2np3A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 36.0 | 3.32e-01 | 77.8% | 49.3% |
| 3a11B01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.56 | 38.0 | 3.67e-01 | 98.1% | 60.0% |
| 1wvuB02 | 1.10.530.10 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.55 | 49.0 | 4.06e-01 | 99.1% | 94.9% |
| 7smgD00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.55 | 41.0 | 3.84e-01 | 80.6% | 79.6% |
| 1aisB01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.54 | 39.0 | 4.09e-01 | 75.9% | 98.0% |
| 2j1oA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 47.0 | 3.68e-01 | 100.0% | 98.4% |
| 1sg6A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.53 | 40.0 | 3.33e-01 | 79.6% | 93.9% |
| 3we9A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 41.0 | 3.23e-01 | 84.3% | 94.7% |
| 4p53A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.53 | 40.0 | 3.37e-01 | 81.5% | 78.5% |
| 3h4cA02 | 1.10.472.110 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › | 0.53 | 43.0 | 4.31e-01 | 88.0% | 93.6% |
| 3b0xA01 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.52 | 39.0 | 4.27e-01 | 84.3% | 98.9% |
| 2qibB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 35.0 | 2.83e-01 | 80.6% | 35.1% |
| 1v4eA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.52 | 44.0 | 3.37e-01 | 96.3% | 100.0% |
| 5vbfA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.52 | 44.0 | 3.25e-01 | 93.5% | 70.1% |
| 2qf9A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 36.0 | 3.28e-01 | 73.1% | 81.4% |
| 2pbxA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 34.0 | 2.79e-01 | 77.8% | 36.5% |
| 6wcsA02 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.51 | 43.0 | 3.55e-01 | 94.4% | 91.8% |
| 1c9bA02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.51 | 39.0 | 3.97e-01 | 81.5% | 89.6% |
| 3k9dA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.51 | 43.0 | 3.33e-01 | 93.5% | 77.5% |
| 1xioA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 42.0 | 3.45e-01 | 92.6% | 83.9% |
| 4jd9G00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.51 | 38.0 | 3.70e-01 | 78.7% | 74.2% |
| 1fx8A00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.51 | 42.0 | 3.29e-01 | 92.6% | 68.1% |
| 4logB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.51 | 44.0 | 3.52e-01 | 100.0% | 74.1% |
| 3zokA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.50 | 37.0 | 3.19e-01 | 79.6% | 91.1% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3838843 | 5065.1.1.2 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD | 0.60 | 46.0 | 3.34e-01 | 82.4% | 70.0% |
| 4368947 | 141.1.1.6 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › HEPPP_synt_1 | 0.58 | 50.0 | 3.93e-01 | 99.1% | 92.4% |
| 3938517 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.57 | 40.0 | 3.37e-01 | 71.3% | 51.4% |
| 5056205 | 2485.1.1.67 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › GILT | 0.54 | 48.0 | 3.96e-01 | 100.0% | 62.5% |
| 5004943 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.54 | 37.0 | 3.30e-01 | 70.4% | 93.1% |
| 3949072 | 2004.1.1.221 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › P-loop_TraG | 0.54 | 42.0 | 2.88e-01 | 86.1% | 36.4% |
| 3023248 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.52 | 43.0 | 3.49e-01 | 92.6% | 84.6% |
| 4981678 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 38.0 | 2.99e-01 | 78.7% | 64.5% |
| 5009678 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 37.0 | 3.18e-01 | 74.1% | 76.0% |
| 4076240 | 4002.1.1.4 ↗ | alpha bundles › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › DHQS_C | 0.51 | 38.0 | 3.27e-01 | 80.6% | 91.9% |
| 3279508 | 283.1.1.4 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase › ThrE | 0.51 | 38.0 | 3.59e-01 | 79.6% | 86.7% |
| 5052475 | 131.1.1.3 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD | 0.51 | 34.0 | 3.27e-01 | 96.3% | 57.7% |
| 3383044 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.50 | 36.0 | 3.60e-01 | 73.1% | 80.6% |
| 3186203 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.50 | 38.0 | 2.78e-01 | 81.5% | 86.8% |
| 4400333 | 109.37.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Anion channel SLAC1-related › Anion channel SLAC1-related › DUF2776 | 0.50 | 44.0 | 3.21e-01 | 100.0% | 85.0% |
| 4988860 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.50 | 35.0 | 2.98e-01 | 100.0% | 44.6% |
| 3930048 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.50 | 38.0 | 3.45e-01 | 83.3% | 95.6% |