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IMGVR_UViG_3300031280_000041-3300031280-Ga0307428_100116420

Arc-Vir

IMGVR_UViG_3300031280_000041-3300031280-Ga0307428_100116420

Quality

87.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-85_214-303
PDB
Domain cluster: representative
CATH (49)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.75 31.0 4.54e-01 74.3% 85.7%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.73 40.0 4.90e-01 89.5% 84.1%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.71 42.0 5.06e-01 100.0% 89.1%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.71 47.0 5.61e-01 94.7% 96.6%
1r2jA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 48.0 5.23e-01 100.0% 81.9%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.71 46.0 4.92e-01 100.0% 75.5%
3p4tA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 51.0 5.42e-01 100.0% 84.7%
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 50.0 5.38e-01 73.1% 95.9%
2rfqC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 50.0 5.02e-01 100.0% 72.6%
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.69 46.0 5.39e-01 84.8% 98.3%
7w9wA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.68 57.0 4.91e-01 88.3% 93.5%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 49.0 5.64e-01 77.2% 100.0%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 47.0 5.14e-01 100.0% 87.0%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.67 40.0 4.99e-01 100.0% 98.0%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.67 43.0 4.53e-01 100.0% 71.5%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 41.0 4.66e-01 100.0% 79.7%
6q9jB02 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.66 34.0 4.46e-01 96.5% 92.0%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.66 42.0 5.08e-01 100.0% 98.2%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.66 42.0 5.07e-01 100.0% 94.8%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.66 48.0 5.39e-01 86.5% 97.0%
2ix5A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.66 50.0 5.22e-01 100.0% 85.8%
8cdaB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 51.0 5.34e-01 100.0% 88.7%
3jrtA00 1.20.120.1060 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.64 46.0 4.68e-01 73.1% 98.8%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 40.0 4.34e-01 94.2% 73.9%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 43.0 5.00e-01 74.3% 98.3%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.63 45.0 5.01e-01 88.9% 90.0%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.62 36.0 4.51e-01 88.9% 94.2%
1ug7A00 1.20.120.360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain 0.62 41.0 4.63e-01 83.0% 88.3%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.62 35.0 3.63e-01 95.3% 58.5%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 45.0 4.93e-01 100.0% 93.5%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 30.0 4.07e-01 83.6% 88.2%
2lquA01 1.20.1420.40 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein 0.60 37.0 3.90e-01 73.1% 65.6%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.60 43.0 4.79e-01 74.3% 92.7%
2e8gA01 1.20.1440.150 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.60 41.0 4.70e-01 100.0% 95.2%
5dkoA02 1.10.3900.10 Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like 0.58 42.0 4.26e-01 73.1% 97.6%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.58 42.0 4.16e-01 74.9% 76.6%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.58 40.0 3.32e-01 70.8% 98.1%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.57 32.0 4.08e-01 84.8% 91.2%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.57 38.0 4.47e-01 99.4% 99.1%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.57 48.0 4.54e-01 88.9% 79.2%
1iq0A03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.56 32.0 3.86e-01 88.3% 83.6%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.55 39.0 4.38e-01 74.9% 93.2%
1zp2A01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.55 29.0 3.36e-01 97.7% 69.6%
4nrhB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 31.0 3.17e-01 91.2% 57.1%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.52 33.0 3.70e-01 93.6% 80.5%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 33.0 4.02e-01 83.0% 100.0%
4bejB02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.51 37.0 3.45e-01 74.9% 87.4%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.51 31.0 3.75e-01 89.5% 89.7%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.50 43.0 3.79e-01 90.1% 82.4%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5037480 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.82 76.0 6.33e-01 98.8% 88.8%
3652435 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.73 48.0 5.45e-01 100.0% 88.8%
3436634 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.70 45.0 4.76e-01 100.0% 71.6%
3602540 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.69 51.0 5.75e-01 76.0% 99.3%
3257419 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.69 39.0 4.64e-01 100.0% 79.2%
3336731 7015.1.1.1 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC 0.69 45.0 4.70e-01 100.0% 70.6%
3800481 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.69 45.0 4.84e-01 100.0% 76.0%
3420292 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 45.0 4.83e-01 100.0% 76.7%
3316910 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 43.0 4.57e-01 100.0% 70.3%
3596738 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.68 40.0 4.36e-01 88.3% 69.0%
3810674 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 43.0 5.11e-01 99.4% 94.8%
3826980 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 41.0 4.30e-01 100.0% 64.4%
3645195 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.67 45.0 4.65e-01 100.0% 72.2%
3315159 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.67 44.0 4.54e-01 100.0% 69.4%
3360919 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.67 44.0 4.72e-01 100.0% 77.1%
3396848 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.67 42.0 4.78e-01 100.0% 84.7%
3802170 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.67 43.0 4.54e-01 100.0% 72.0%
4972007 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.67 43.0 4.70e-01 100.0% 78.6%
3733651 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.66 44.0 4.74e-01 100.0% 77.3%
3338353 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.66 43.0 4.47e-01 100.0% 70.0%
4001943 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.63 42.0 4.93e-01 100.0% 95.0%
3808186 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.63 40.0 4.32e-01 100.0% 74.5%
3443462 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.63 41.0 4.96e-01 90.1% 98.3%
3879044 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.62 42.0 4.85e-01 100.0% 94.4%
3913234 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.61 41.0 4.55e-01 100.0% 85.2%
3815161 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.61 38.0 3.96e-01 100.0% 67.1%
3319537 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.61 40.0 4.24e-01 100.0% 73.4%
3314513 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.61 39.0 4.00e-01 100.0% 66.3%
3410818 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.60 40.0 4.60e-01 70.8% 90.4%
3253939 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.59 41.0 4.79e-01 70.8% 100.0%
3176858 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.59 42.0 4.58e-01 100.0% 89.3%
3410763 5001.1.1.79 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › YhhN 0.59 49.0 4.55e-01 89.5% 90.0%
3799484 633.26.1.3 alpha bundles › Bromodomain-like › SidC lipid-binding domain › SidC lipid-binding domain › PF31009 0.59 44.0 4.50e-01 100.0% 79.4%
3878975 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.59 43.0 4.70e-01 100.0% 92.1%
3195245 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.58 46.0 4.48e-01 83.0% 79.5%
3939799 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 43.0 4.71e-01 100.0% 94.3%
3663333 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.58 40.0 4.01e-01 99.4% 68.6%
3238741 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.58 41.0 3.86e-01 71.3% 64.9%
3235794 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 42.0 4.56e-01 100.0% 90.0%
3423837 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.58 38.0 3.93e-01 100.0% 70.0%
3868831 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.56 40.0 4.09e-01 100.0% 75.2%
3852296 3755.3.1.123 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin 0.56 50.0 4.97e-01 97.1% 91.4%
3895743 3615.1.1.7 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › CD20 0.56 47.0 4.60e-01 100.0% 80.5%
3503770 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.54 42.0 4.49e-01 100.0% 93.8%
3373991 5001.1.1.10 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Ceramidase 0.54 45.0 4.08e-01 88.3% 87.8%
3541787 4177.2.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › TBK1_CCD1 0.54 46.0 3.85e-01 89.5% 71.6%
4947944 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 44.0 3.61e-01 100.0% 48.9%
3839889 601.51.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin 0.52 38.0 4.13e-01 74.9% 88.3%
3815650 604.1.1.134 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF28715 0.52 45.0 4.19e-01 100.0% 74.6%
4003320 109.4.1.37 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 0.52 38.0 3.32e-01 75.4% 58.9%
3708756 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 37.0 3.51e-01 71.9% 60.5%
3479676 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 38.0 3.80e-01 75.4% 71.7%
3577573 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.52 43.0 4.55e-01 100.0% 96.8%
3592681 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.52 44.0 3.54e-01 89.5% 65.6%
3550685 4177.1.1.38 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Tektin 0.52 45.0 4.54e-01 91.8% 93.7%
3608199 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.52 44.0 4.30e-01 89.5% 86.5%
3613315 1189.1.1.3 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › GARP 0.51 43.0 4.17e-01 90.1% 86.2%
3837620 3562.1.1.10 alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › DUF599 0.51 44.0 3.94e-01 98.8% 67.4%
3186741 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 39.0 3.53e-01 80.7% 62.1%
D2 high residues 315-370
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1escA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.64 47.0 2.98e-01 78.6% 84.4%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
None 0.58 47.0 3.41e-01 91.1% 79.4%
3703625 7585.1.1.1 a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 0.54 33.0 2.63e-01 96.4% 31.8%
D3 medium residues 88-142
PDB
Domain cluster: representative
CATH (90)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ezjA02 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.78 60.0 5.60e-01 100.0% 67.6%
2kt2A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.78 60.0 5.56e-01 98.2% 66.7%
3keyA02 3.30.1370.230 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › Stn1, C-terminal wHTH domain 0.78 68.0 5.85e-01 100.0% 77.3%
1el6A03 3.90.1160.10 Alpha Beta › Alpha-Beta Complex › Baseplate Structural Protein Gp11; Chain: A, domain 3 › Baseplate structural protein gp11, finger domain 0.77 67.0 5.42e-01 100.0% 73.4%
1qupA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.77 59.0 5.46e-01 100.0% 65.7%
2grvA02 3.90.76.10 Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 0.76 67.0 5.32e-01 100.0% 56.6%
2crlA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.76 58.0 5.42e-01 100.0% 66.7%
1cc8A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.76 59.0 5.42e-01 100.0% 65.3%
1i6uA01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.75 57.0 5.33e-01 100.0% 66.2%
3onqA02 3.30.70.2730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.74 59.0 5.19e-01 98.2% 59.3%
1fvqA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.74 57.0 5.28e-01 100.0% 65.3%
1vbkA01 3.30.70.1510 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › THUMP domain-like 0.74 63.0 5.59e-01 100.0% 67.5%
1mwyA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 56.0 5.15e-01 100.0% 64.4%
2kkhA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 55.0 5.05e-01 100.0% 62.7%
4pcqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.71 54.0 4.75e-01 100.0% 54.8%
3njfA00 2.60.40.420 Mainly Beta › Sandwich › Immunoglobulin-like › Cupredoxins - blue copper proteins 0.70 54.0 4.39e-01 100.0% 42.9%
3mahA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 49.0 4.56e-01 100.0% 58.6%
2dchX01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.69 54.0 4.53e-01 100.0% 50.5%
2cdqA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.69 53.0 4.72e-01 100.0% 57.1%
2mzwA01 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.68 52.0 4.74e-01 100.0% 61.8%
1wg1A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.68 50.0 4.65e-01 100.0% 62.0%
2b4vA03 3.30.70.1970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 54.0 4.50e-01 100.0% 49.5%
5xamA02 3.30.70.3220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 57.0 4.11e-01 100.0% 32.9%
3c1mA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.67 52.0 3.81e-01 100.0% 29.9%
1wexA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.67 50.0 4.61e-01 100.0% 61.6%
2ifxA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 53.0 4.73e-01 100.0% 59.1%
2l9wA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.67 54.0 4.37e-01 100.0% 46.3%
2av5A00 3.30.70.3250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribonuclease P, Pop5 subunit 0.67 56.0 4.65e-01 100.0% 58.5%
2vz6B01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.67 56.0 4.93e-01 100.0% 63.9%
6n3oA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.67 57.0 4.88e-01 100.0% 60.0%
2e29A01 3.30.70.2280 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 53.0 4.88e-01 100.0% 67.1%
4c2mA09 3.30.70.2850 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 56.0 4.03e-01 100.0% 75.3%
5dx9A01 3.30.70.1020 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Trehalose-6-phosphate phosphatase related protein; domain 2 0.66 54.0 4.98e-01 100.0% 70.8%
4lniA02 3.30.590.10 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › Glutamine synthetase/guanido kinase, catalytic domain 0.66 55.0 3.45e-01 100.0% 21.4%
2cpqA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.66 53.0 5.08e-01 100.0% 78.1%
1fjeB01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.65 55.0 4.89e-01 100.0% 65.4%
3jb9a02 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.65 45.0 4.33e-01 100.0% 63.5%
3pm9A04 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 56.0 4.86e-01 100.0% 66.7%
4clfA02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.64 54.0 3.84e-01 100.0% 35.9%
2rt3A00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 48.0 4.07e-01 100.0% 47.4%
3gz7B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 53.0 4.52e-01 100.0% 57.1%
2khdA00 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 55.0 4.48e-01 100.0% 50.9%
3w9iA06 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.63 51.0 4.42e-01 100.0% 63.7%
7cqnC01 3.30.590.10 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › Glutamine synthetase/guanido kinase, catalytic domain 0.63 53.0 3.36e-01 100.0% 24.2%
1tuwA00 3.30.70.1090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. 0.63 54.0 4.45e-01 100.0% 51.9%
8f4rA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.63 51.0 4.45e-01 98.2% 66.7%
1r89A03 3.30.70.590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain 0.63 52.0 4.09e-01 100.0% 44.8%
2atzA00 3.90.920.20 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › HP0184-like 0.63 50.0 3.60e-01 100.0% 29.0%
1m5yA03 3.10.50.40 Alpha Beta › Roll › Chitinase A; domain 3 › 0.63 52.0 4.38e-01 100.0% 90.7%
5k9fA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 52.0 4.38e-01 100.0% 52.4%
4d9uA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.63 48.0 4.23e-01 100.0% 54.5%
2q14A02 1.20.1250.30 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.63 44.0 3.11e-01 74.5% 41.0%
2g4bA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.63 53.0 4.49e-01 96.4% 64.5%
6k3lB02 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.63 49.0 4.30e-01 100.0% 56.0%
4kx7A01 2.60.40.1730 Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain 0.62 48.0 3.18e-01 100.0% 21.0%
3dfeA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 46.0 4.07e-01 85.5% 53.7%
4oi3A00 3.30.70.3090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ORF SCO4226, nickel-binding ferredoxin-like monomer 0.62 53.0 4.73e-01 100.0% 69.1%
6hhuA01 2.60.40.1220 Mainly Beta › Sandwich › Immunoglobulin-like › 0.62 51.0 4.59e-01 100.0% 64.1%
1cvjH02 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 40.0 4.08e-01 100.0% 69.2%
3znuA00 3.30.70.1060 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel 0.62 52.0 4.48e-01 100.0% 59.6%
1x19A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 44.0 3.33e-01 100.0% 28.1%
3tp2B02 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 52.0 4.42e-01 100.0% 56.8%
1zbtA02 3.30.70.1660 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 50.0 3.76e-01 100.0% 60.7%
1u5qA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.61 50.0 4.31e-01 100.0% 56.2%
1zpvA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.61 50.0 4.42e-01 100.0% 62.4%
5wt3A01 3.30.70.2580 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 42.0 4.09e-01 100.0% 64.6%
3kepA00 3.30.1610.10 Alpha Beta › 2-Layer Sandwich › c-terminal autoproteolytic domain of nucleoporin nup98 › Peptidase S59, nucleoporin 0.60 49.0 3.67e-01 100.0% 35.4%
6hhnA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 51.0 4.43e-01 100.0% 64.1%
4qmfB01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.60 49.0 4.43e-01 100.0% 64.6%
3n79A01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.59 48.0 4.32e-01 98.2% 64.1%
2kjwA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.59 50.0 4.25e-01 100.0% 83.3%
3i3wA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.59 48.0 4.42e-01 100.0% 74.0%
4h05B01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.59 46.0 4.04e-01 94.5% 56.0%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.59 45.0 3.90e-01 98.2% 51.6%
5xbtA01 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.58 47.0 3.56e-01 94.5% 41.5%
3gtzA00 3.30.1330.40 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › RutC-like 0.58 47.0 3.90e-01 100.0% 81.7%
1whrA00 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.57 41.0 3.17e-01 76.4% 50.0%
2zzeA04 3.30.980.10 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Threonyl-trna Synthetase; Chain A, domain 2 0.57 48.0 4.09e-01 96.4% 58.9%
4js8A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 46.0 4.12e-01 100.0% 62.9%
2v94B00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 49.0 4.20e-01 100.0% 61.3%
2xzmP00 3.30.70.3370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 48.0 3.58e-01 98.2% 40.5%
2yx0A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.56 46.0 2.97e-01 100.0% 17.0%
5optY00 3.30.70.3370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 46.0 3.71e-01 100.0% 48.0%
3ibwA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.56 45.0 4.09e-01 100.0% 65.8%
5xyiY00 3.30.70.3370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 46.0 3.76e-01 100.0% 49.5%
2wbmA03 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 42.0 3.92e-01 98.2% 67.1%
3b82A06 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 47.0 3.72e-01 100.0% 60.3%
2gaxA00 3.40.1490.10 Alpha Beta › 3-Layer(aba) Sandwich › Bit1 › Bit1 0.55 43.0 3.20e-01 87.3% 35.1%
4ymhD00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 44.0 3.02e-01 100.0% 29.1%
2crqA01 3.30.110.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Translation initiation factor 3 (IF-3), C-terminal domain 0.54 43.0 3.91e-01 100.0% 64.0%
ECOD (95)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3661117 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.79 62.0 5.71e-01 100.0% 67.1%
3657793 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.79 59.0 5.65e-01 100.0% 69.2%
3674421 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.78 60.0 5.57e-01 100.0% 65.7%
3350503 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.78 61.0 5.27e-01 100.0% 55.3%
3838249 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.78 60.0 5.25e-01 100.0% 55.3%
1145702 101.1.2.134 alpha arrays › HTH › HTH › winged helix domain › Stn1_C 0.78 68.0 5.83e-01 100.0% 76.4%
4978147 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.77 60.0 5.11e-01 100.0% 52.2%
4014842 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.76 58.0 5.54e-01 100.0% 70.8%
5143 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.76 59.0 5.42e-01 100.0% 65.3%
3654160 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.75 62.0 5.62e-01 100.0% 68.0%
3666212 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.75 57.0 5.30e-01 100.0% 65.7%
3803359 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.73 55.0 4.93e-01 100.0% 57.5%
4980062 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.71 55.0 4.64e-01 100.0% 49.5%
3224075 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.71 57.0 3.66e-01 100.0% 19.6%
4536686 304.120.1.6 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.71 62.0 5.51e-01 100.0% 72.5%
4443601 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.71 61.0 5.34e-01 100.0% 67.1%
4979949 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.71 55.0 4.87e-01 100.0% 58.7%
5038034 304.120.1.6 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.70 60.0 5.20e-01 100.0% 62.2%
3168157 304.17.1.2 a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN 0.70 61.0 5.03e-01 100.0% 56.0%
4358940 304.8.1.21 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.69 54.0 4.79e-01 100.0% 57.6%
3616815 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.69 60.0 5.89e-01 100.0% 91.7%
3379093 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.69 60.0 5.61e-01 100.0% 78.6%
3595583 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.68 56.0 4.55e-01 100.0% 47.6%
4971846 321.1.1.7 a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › GCS2 0.68 57.0 3.52e-01 100.0% 19.2%
3614195 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.67 55.0 4.47e-01 100.0% 47.6%
3402529 206.1.1.72 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Pkinase_fungal 0.67 57.0 3.51e-01 100.0% 15.7%
4987066 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.67 56.0 4.57e-01 100.0% 53.9%
3565930 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.67 54.0 4.81e-01 100.0% 62.5%
3180285 323.1.1.12 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › TRI-like_N 0.67 57.0 3.91e-01 100.0% 64.4%
3669520 1036.1.1.1 a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 0.66 55.0 4.62e-01 100.0% 53.0%
3593360 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.66 52.0 4.47e-01 100.0% 53.3%
3592854 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.66 53.0 4.51e-01 100.0% 52.6%
3672813 304.28.1.7 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › tRNA_synt_2f 0.66 55.0 5.33e-01 100.0% 92.3%
4614246 304.20.1.5 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › tRNA_synt_2f 0.66 56.0 3.82e-01 100.0% 27.9%
2075771 304.28.1.4 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.66 54.0 5.02e-01 100.0% 72.6%
4947140 304.57.1.0 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like 0.65 54.0 4.56e-01 100.0% 59.0%
4034289 304.4.1.19 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › SCO4226-like 0.65 54.0 4.67e-01 100.0% 57.9%
4998366 321.1.1.7 a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › GCS2 0.65 53.0 3.34e-01 100.0% 18.3%
3225575 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.64 57.0 5.10e-01 100.0% 85.0%
4968297 304.4.1.2 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MIase 0.64 55.0 4.84e-01 100.0% 65.9%
5019545 328.5.1.1 a+b two layers › IF3-like › SirA-like › SirA-like › TusA 0.64 46.0 4.28e-01 100.0% 58.7%
5011827 304.4.1.2 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MIase 0.64 54.0 4.58e-01 100.0% 56.0%
4854269 304.4.1.7 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Cyclase_polyket 0.64 55.0 4.56e-01 100.0% 53.8%
3877587 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.64 56.0 4.64e-01 100.0% 56.0%
3608814 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.64 54.0 4.09e-01 100.0% 38.6%
3285016 304.4.1.3 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › YCII 0.63 53.0 4.59e-01 100.0% 58.9%
4552979 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.63 53.0 3.92e-01 100.0% 36.9%
4174585 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.63 55.0 4.00e-01 100.0% 39.0%
3738318 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.63 52.0 4.67e-01 100.0% 66.3%
3707051 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.63 53.0 3.56e-01 100.0% 22.5%
1515958 206.1.1.78 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kinase-like 0.63 54.0 4.03e-01 100.0% 38.0%
4571276 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.63 54.0 4.83e-01 100.0% 71.2%
5026545 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.62 52.0 3.73e-01 100.0% 33.3%
4933323 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.62 53.0 3.74e-01 100.0% 30.3%
3187311 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.62 53.0 4.44e-01 100.0% 57.0%
4115819 304.48.1.48 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.62 51.0 3.68e-01 100.0% 31.2%
3499766 3914.1.1.0 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain 0.61 47.0 2.62e-01 85.5% 43.4%
5052336 304.4.1.75 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › GYD 0.61 50.0 4.36e-01 100.0% 58.9%
3280014 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.61 49.0 3.25e-01 100.0% 19.6%
3250368 304.4.1.8 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › rhaM 0.61 52.0 4.15e-01 100.0% 49.2%
5080869 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.61 51.0 4.53e-01 100.0% 65.9%
5025438 304.4.1.8 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › rhaM 0.61 51.0 4.31e-01 100.0% 57.0%
3797513 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.60 50.0 3.23e-01 100.0% 35.8%
3172633 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 53.0 4.26e-01 100.0% 50.0%
3966291 886.1.1.0 a+b duplicates or obligate multimers › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain 0.60 51.0 3.72e-01 98.2% 39.4%
3596486 206.1.1.71 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo 0.60 50.0 3.17e-01 100.0% 17.1%
4956872 304.120.1.20 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › DUF2110_N 0.60 50.0 4.69e-01 98.2% 82.9%
3885537 327.16.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system 0.60 50.0 4.66e-01 100.0% 76.0%
3665372 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 52.0 4.33e-01 100.0% 95.0%
3779828 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.59 52.0 3.90e-01 100.0% 40.0%
3176674 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 48.0 3.04e-01 100.0% 14.5%
4025755 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 48.0 3.20e-01 100.0% 19.6%
4488103 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.59 49.0 4.30e-01 100.0% 63.3%
3284390 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.59 50.0 4.15e-01 100.0% 52.4%
None 0.59 42.0 3.58e-01 87.3% 45.3%
3687618 304.9.1.79 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF28976 0.59 49.0 3.58e-01 100.0% 32.7%
3838922 872.10.1.0 a+b two layers › Dodecin subunit-like › Secreted protein HP1454 N-terminal domain › Secreted protein HP1454 N-terminal domain 0.59 49.0 4.24e-01 92.7% 74.1%
5032602 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.58 49.0 3.97e-01 100.0% 47.8%
4991134 304.8.1.120 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › CAA_C 0.58 47.0 3.68e-01 100.0% 41.4%
3540753 206.1.1.71 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo 0.58 47.0 3.12e-01 100.0% 19.3%
3832799 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.58 49.0 3.12e-01 100.0% 18.1%
3218176 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.58 49.0 3.14e-01 100.0% 18.1%
3735854 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.58 46.0 2.96e-01 100.0% 18.6%
4095823 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.57 48.0 4.21e-01 100.0% 64.8%
4567496 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.57 47.0 4.36e-01 100.0% 73.3%
3273294 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.57 46.0 2.93e-01 100.0% 31.4%
3829359 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.56 46.0 4.17e-01 100.0% 71.8%
4679172 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.56 47.0 4.25e-01 100.0% 70.0%
4239881 328.3.1.2 a+b two layers › IF3-like › Translation initiation factor IF3, C-terminal domain › Translation initiation factor IF3, C-terminal domain › mIF3 0.56 47.0 3.75e-01 100.0% 82.4%
5053175 229.1.1.0 a+b two layers › Cdc48 domain 2-like › Cdc48 domain 2-like › Cdc48 domain 2-like 0.56 43.0 3.81e-01 85.5% 94.1%
3592492 304.109.1.0 a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e 0.56 46.0 3.68e-01 100.0% 47.2%
3215882 304.8.1.72 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › SCVP 0.55 45.0 4.01e-01 100.0% 66.7%
3980760 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 47.0 3.43e-01 100.0% 36.4%
3704413 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.54 44.0 2.72e-01 100.0% 16.5%
3589477 872.1.1.0 a+b two layers › Dodecin subunit-like › Flavin-binding protein dodecin-like › Flavin-binding protein dodecin-like 0.52 41.0 4.20e-01 92.7% 100.0%