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IMGVR_UViG_3300031555_007761-3300031555-Ga0318466_101257148

Arc-Vir

IMGVR_UViG_3300031555_007761-3300031555-Ga0318466_101257148

Quality

90.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-67
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3eupB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 46.0 3.36e-01 97.0% 51.0%
2b48A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.52 39.0 3.04e-01 100.0% 37.8%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3540079 592.1.1.0 alpha arrays › PWI domain-like › PWI domain › PWI domain 0.56 34.0 3.24e-01 70.1% 51.2%
3203789 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.55 46.0 3.33e-01 100.0% 37.3%
3627400 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.52 42.0 3.35e-01 92.5% 75.3%
3447321 109.4.1.1364 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_PATROL1, PF27629 0.50 42.0 2.81e-01 95.5% 34.2%
D2 medium residues 68-237
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3d03A01 3.60.21.40 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › GpdQ, catalytic alpha/beta sandwich domain 0.65 33.0 3.74e-01 82.9% 62.6%
1f2uB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 32.0 3.47e-01 87.6% 55.2%
4pkcC00 6.20.90.20 Special › Other non-globular › SH3 type barrels. › Benzylsuccinate synthase gamma subunit 0.61 14.0 2.87e-01 71.8% 75.6%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 26.0 3.68e-01 72.9% 93.3%
2vkjA00 1.20.58.2030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 27.0 3.39e-01 71.8% 73.6%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 34.0 3.66e-01 86.5% 72.2%
2xzeB00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 34.0 3.75e-01 73.5% 77.5%
4i1eA03 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.53 37.0 4.10e-01 72.4% 98.6%
4jgwA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.53 34.0 3.51e-01 84.1% 68.6%
1qmgB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 35.0 3.31e-01 71.8% 85.6%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3964363 1051.1.1.0 alpha superhelices › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain 0.67 33.0 4.24e-01 74.1% 82.1%
3568690 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.56 32.0 2.22e-01 84.7% 16.5%
3785134 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 36.0 3.42e-01 77.1% 54.9%
1278602 223.3.1.1 a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase 0.54 22.0 3.44e-01 84.1% 100.0%
3957084 4019.1.1.1 alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase 0.53 23.0 3.17e-01 87.1% 80.0%
3597336 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 39.0 3.56e-01 84.7% 61.8%
D3 medium residues 238-331
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.71 49.0 4.87e-01 70.2% 77.3%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.68 46.0 4.36e-01 70.2% 73.3%
4dlqA02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 43.0 4.34e-01 70.2% 66.3%
3nf2A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.65 47.0 3.22e-01 75.5% 89.9%
2pbeA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.63 44.0 3.97e-01 71.3% 84.9%
1mhyD00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.60 53.0 3.34e-01 100.0% 30.0%
1s9qA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.58 47.0 3.59e-01 88.3% 84.4%
1y4uB01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.58 40.0 3.16e-01 71.3% 93.3%
2r9rH02 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.56 44.0 3.78e-01 84.0% 75.0%
7vkcA01 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.56 50.0 4.15e-01 98.9% 97.0%
1s7mA03 2.20.25.140 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.55 20.0 2.98e-01 77.7% 89.3%
1td6A02 3.30.1790.10 Alpha Beta › 2-Layer Sandwich › hypothetical protein mp506/mpn330, domain 2 › hypothetical protein mp506/mpn330, domain 2 0.55 40.0 4.06e-01 90.4% 77.2%
1x0gA00 2.60.300.12 Mainly Beta › Sandwich › Hypothetical Protein Aq_1857; Chain: A; › HesB-like domain 0.52 34.0 3.39e-01 91.5% 62.7%
3o27B00 2.10.260.10 Mainly Beta › Ribbon › Pemi-like Protein 1; Chain: D › 0.51 28.0 3.51e-01 98.9% 89.5%
1dkqA02 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.51 35.0 3.25e-01 71.3% 74.2%
3k62A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.51 44.0 2.94e-01 98.9% 38.5%
2r7rA05 1.10.357.80 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.50 40.0 3.32e-01 88.3% 58.5%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3610944 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.65 43.0 4.16e-01 89.4% 60.6%
3493444 109.4.1.209 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Katanin_con80 0.64 46.0 3.76e-01 76.6% 63.7%
4025879 632.2.1.42 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › CLPTM1 0.62 42.0 3.65e-01 72.3% 44.8%
3438721 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.62 52.0 3.99e-01 89.4% 100.0%
3302941 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.62 51.0 3.99e-01 89.4% 99.0%
3894638 603.1.1.19 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-18_N 0.62 52.0 3.86e-01 88.3% 80.0%
3741385 377.1.1.12 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › zf-C5HC2 0.61 41.0 3.68e-01 70.2% 83.7%
4021428 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.60 46.0 3.51e-01 81.9% 68.2%
4025195 4133.1.1.0 alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like 0.60 50.0 4.13e-01 90.4% 80.0%
3599897 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.60 46.0 3.38e-01 80.9% 90.6%
5013136 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 47.0 3.39e-01 83.0% 43.5%
5034882 4203.1.1.0 few secondary structure elements › HSP33 redox switch-like › HSP33 redox switch-like › HSP33 redox switch-like 0.58 24.0 3.32e-01 84.0% 77.8%
3607480 376.1.1.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.58 42.0 3.22e-01 74.5% 47.0%
4015817 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 49.0 3.19e-01 97.9% 59.1%
None 0.57 39.0 2.94e-01 71.3% 46.5%
3887336 101.1.4.12 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › MSC 0.56 40.0 3.00e-01 74.5% 42.7%
3305137 3569.1.1.0 extended segments › Epidermal growth factor receptor transmembrane-juxtamembrane segment-like › Epidermal growth factor receptor transmembrane-juxtamembrane segment › Epidermal growth factor receptor transmembrane-juxtamembrane segment 0.55 29.0 3.39e-01 98.9% 71.9%
5045308 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.54 38.0 3.07e-01 72.3% 86.7%
3771203 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 47.0 3.29e-01 100.0% 62.5%
4004088 389.1.1.0 few secondary structure elements › EGF-like › EGF-related › EGF/Laminin 0.53 23.0 3.21e-01 79.8% 90.0%
4310506 101.1.2.312 alpha arrays › HTH › HTH › winged helix domain › MSC 0.52 38.0 2.83e-01 75.5% 35.6%
3830411 109.4.1.1254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.52 40.0 2.53e-01 81.9% 36.0%
3685640 1128.1.1.0 alpha bundles › LYR protein › LYR protein › LYR protein 0.52 38.0 4.04e-01 77.7% 87.1%
3367521 109.4.1.1254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.51 36.0 2.68e-01 75.5% 67.3%
4638770 601.48.1.0 alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain 0.50 35.0 3.57e-01 72.3% 77.8%
D4 medium residues 332-435
PDB
Domain cluster: representative
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3fflA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.70 44.0 4.14e-01 85.6% 52.4%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 49.0 4.77e-01 88.5% 77.8%
4ol8B03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 32.0 3.45e-01 76.9% 57.8%
3a6pA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.61 51.0 2.96e-01 94.2% 17.5%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.57 45.0 3.70e-01 87.5% 54.5%
4ipeB02 3.30.230.80 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.55 46.0 4.00e-01 92.3% 93.9%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 45.0 4.40e-01 90.4% 91.2%
4hz4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 44.0 4.31e-01 91.3% 87.5%
1urvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 38.0 3.43e-01 76.0% 89.0%
5ojcA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 39.0 3.49e-01 77.9% 57.8%
3lxrF00 1.10.4120.20 Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › 0.52 37.0 3.10e-01 72.1% 66.9%
2yv9B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 43.0 3.99e-01 94.2% 70.1%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.52 38.0 3.74e-01 76.9% 71.1%
3hyuA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 37.0 3.39e-01 76.0% 61.7%
2kj8A00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.51 35.0 3.41e-01 71.2% 79.7%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 41.0 4.00e-01 95.2% 79.5%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3471984 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.67 50.0 5.08e-01 88.5% 77.1%
4214723 109.4.1.1248 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF2753 0.62 50.0 4.66e-01 89.4% 69.2%
3673142 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 54.0 3.80e-01 100.0% 84.7%
3743053 3628.1.1.1 a+b complex topology › Transcription factor tau 60 kDa subunit › Transcription factor tau 60 kDa subunit › Transcription factor tau 60 kDa subunit › zf-TFIIIC 0.62 46.0 3.74e-01 92.3% 42.0%
3802524 109.4.1.1382 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_3, TPR_24 0.61 41.0 3.54e-01 92.3% 43.0%
5067623 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 43.0 4.24e-01 76.9% 95.5%
3692148 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 48.0 4.25e-01 91.3% 65.3%
3276430 109.4.1.563 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3437 0.55 47.0 3.43e-01 95.2% 76.4%
3176663 603.1.1.207 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF30350 0.55 45.0 4.28e-01 91.3% 93.8%
3685556 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 43.0 3.67e-01 87.5% 49.7%
3924662 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 40.0 4.21e-01 77.9% 94.7%
3258505 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.55 44.0 3.95e-01 90.4% 71.6%
50002 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.53 39.0 3.51e-01 77.9% 58.9%
3457663 192.29.1.178 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF28703 0.53 38.0 3.80e-01 75.0% 73.3%
380191 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.53 39.0 3.48e-01 77.9% 57.8%
D5 medium residues 436-594
PDB
Domain cluster: representative
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6orcB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 33.0 3.62e-01 100.0% 64.2%
3mekA04 1.25.40.970 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 30.0 3.92e-01 89.9% 92.5%
3p5nA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.58 41.0 4.12e-01 77.4% 69.0%
3dwlG00 1.25.40.190 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5 0.58 37.0 4.25e-01 100.0% 88.6%
1rx0C01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.58 40.0 4.55e-01 73.6% 92.7%
4l9mA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.57 41.0 4.43e-01 92.5% 88.0%
2fnoA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 40.0 4.16e-01 71.7% 91.0%
8f7aA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.57 51.0 3.39e-01 100.0% 35.8%
3zgzA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.56 32.0 3.13e-01 91.2% 48.6%
3feyA02 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 41.0 3.93e-01 99.4% 64.1%
2or0B01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.56 38.0 4.20e-01 81.8% 87.9%
3o4zA02 1.25.40.720 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tel2 C-terminal domain 0.55 49.0 4.55e-01 100.0% 77.3%
1g2nA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.55 38.0 3.34e-01 71.1% 92.7%
6ok0B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 31.0 3.51e-01 96.2% 71.4%
8cdaC01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.54 39.0 4.44e-01 78.0% 100.0%
2of3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.54 47.0 3.97e-01 100.0% 56.0%
4xriA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.53 49.0 3.04e-01 100.0% 19.9%
3nowA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.52 46.0 3.56e-01 96.2% 53.4%
3wozB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.52 47.0 4.16e-01 100.0% 68.1%
3crdA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.52 24.0 3.01e-01 78.0% 68.0%
3gs3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.52 45.0 3.87e-01 93.7% 70.3%
2ijeS00 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.51 37.0 3.34e-01 75.5% 84.4%
4cb8A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.51 47.0 3.32e-01 100.0% 34.2%
1qgrA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.51 46.0 2.90e-01 100.0% 20.4%
1yowA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.51 39.0 3.48e-01 80.5% 83.0%
3b9wA00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.51 40.0 3.15e-01 84.9% 80.9%
4ffbC00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.50 46.0 4.06e-01 100.0% 76.2%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.50 38.0 3.91e-01 95.6% 83.2%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5048230 1075.1.1.3 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 0.65 51.0 4.43e-01 82.4% 86.1%
4147689 109.4.1.632 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MMS22L_C 0.64 46.0 4.44e-01 98.7% 64.1%
3599900 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.64 49.0 3.34e-01 79.9% 79.8%
5049975 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.64 50.0 4.18e-01 82.4% 87.4%
3709406 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.64 48.0 3.32e-01 78.6% 83.4%
3484674 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 39.0 3.93e-01 100.0% 58.8%
3239412 109.4.1.285 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PSMD12-CSN4_N 0.62 43.0 4.52e-01 100.0% 79.3%
5016157 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 42.0 2.96e-01 70.4% 47.8%
3253027 109.8.1.1 alpha superhelices › Repetitive alpha hairpins › Arp2/3 complex 16 KDa subunit ARPC5 › Arp2/3 complex 16 KDa subunit ARPC5 › P16-Arc 0.61 38.0 4.09e-01 100.0% 71.7%
3917442 109.4.1.1893 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ICE1_C 0.59 44.0 4.06e-01 100.0% 60.5%
3494026 109.4.1.70 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.57 42.0 4.50e-01 100.0% 89.6%
3863745 109.4.1.1870 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_Maestro, HEAT_MROH2B_C 0.56 44.0 2.97e-01 100.0% 20.5%
3247876 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.56 40.0 3.44e-01 94.3% 46.3%
5058884 109.4.1.22 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N 0.54 44.0 3.40e-01 100.0% 40.0%
3631540 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 43.0 3.14e-01 84.9% 72.6%
4018298 109.4.1.761 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Telomere_reg-2 0.54 45.0 3.39e-01 100.0% 36.3%
3806415 4133.1.1.2 alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Tic110 0.53 32.0 3.65e-01 76.1% 80.0%
3921477 109.4.1.645 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BLM10_mid 0.53 49.0 3.86e-01 100.0% 55.2%
3586649 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 48.0 4.33e-01 100.0% 72.3%
4009820 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.52 40.0 3.68e-01 80.5% 88.8%
3756635 109.4.1.839 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Maestro_HEAT 0.52 44.0 3.74e-01 100.0% 55.1%
4941726 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.51 44.0 3.99e-01 93.1% 86.8%
3399610 3352.1.1.13 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › TMTC_DUF1736 0.50 41.0 3.06e-01 86.8% 42.3%
D6 medium residues 595-680
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 51.0 4.97e-01 83.7% 86.7%
2elcA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.66 47.0 5.20e-01 90.7% 97.0%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.64 50.0 4.99e-01 87.2% 89.8%
3oo3A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.63 44.0 2.93e-01 73.3% 77.6%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 44.0 3.87e-01 76.7% 51.1%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.61 51.0 4.29e-01 94.2% 65.8%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.60 52.0 4.49e-01 98.8% 77.3%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 45.0 4.22e-01 83.7% 89.1%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.58 44.0 4.47e-01 82.6% 90.8%
3ihuA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.58 44.0 3.79e-01 81.4% 81.3%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.58 45.0 4.24e-01 84.9% 88.8%
2pusA04 6.10.140.300 Special › Helix non-globular › Helix Hairpins › 0.58 44.0 4.18e-01 84.9% 75.0%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 44.0 3.85e-01 83.7% 72.8%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.57 44.0 4.29e-01 84.9% 90.8%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 43.0 4.12e-01 83.7% 98.0%
3owaA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.56 48.0 4.22e-01 98.8% 71.0%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.56 44.0 4.28e-01 88.4% 85.9%
2p6vA00 1.20.120.1110 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › TAFH/NHR1 domain 0.55 39.0 3.80e-01 74.4% 96.9%
3gwlA00 1.20.120.310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain 0.55 39.0 3.72e-01 76.7% 97.2%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.54 47.0 3.71e-01 100.0% 83.6%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.54 44.0 3.70e-01 91.9% 50.6%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.54 42.0 4.04e-01 87.2% 99.0%
1ylmA00 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.53 43.0 3.69e-01 90.7% 83.1%
2vvyA01 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.52 42.0 3.73e-01 93.0% 58.2%
4ga0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 38.0 3.28e-01 95.3% 47.6%
5dvwA00 1.20.120.1160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.51 41.0 3.57e-01 86.0% 80.3%
2wauA01 1.20.1310.20 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain 0.51 43.0 3.63e-01 96.5% 89.0%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3321667 109.4.1.587 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mon2_C 0.68 59.0 3.53e-01 100.0% 18.8%
3240704 109.4.1.844 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ZSWIM4-8_C 0.66 57.0 3.38e-01 100.0% 24.1%
3616671 604.1.1.155 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF29142 0.65 49.0 4.81e-01 81.4% 82.1%
3248078 109.4.1.3377 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm, IBB, HEAT_PBS, Arm_2, Arm_3 0.64 53.0 3.31e-01 91.9% 16.2%
3646859 109.4.1.241 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3458_C 0.62 55.0 4.30e-01 100.0% 60.6%
4876325 109.4.1.1413 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28415 0.62 51.0 5.10e-01 96.5% 88.6%
5077373 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 52.0 5.01e-01 96.5% 99.0%
3725255 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 51.0 3.93e-01 96.5% 62.9%
3935032 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.60 47.0 4.45e-01 86.0% 93.3%
3602716 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.59 46.0 4.12e-01 84.9% 73.6%
3610769 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.57 49.0 4.34e-01 100.0% 88.5%
1019364 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.56 43.0 3.97e-01 81.4% 86.5%
3485641 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 42.0 4.39e-01 80.2% 94.7%
3624728 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 42.0 4.28e-01 86.0% 87.1%
5061623 7516.1.1.26 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_tranf_2_3 0.53 45.0 3.01e-01 93.0% 65.8%
3262218 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.52 42.0 3.64e-01 91.9% 73.1%
4590389 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.51 41.0 3.48e-01 91.9% 75.5%
3250971 616.1.1.0 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.50 36.0 3.51e-01 76.7% 68.0%