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IMGVR_UViG_3300031992_000232-3300031992-Ga0310694_100008201

Arc-Vir

Identity

Accession:: IMGVR_UViG_3300031992_000232-3300031992-Ga0310694_100008201 ↗
Kingdom:: archaea

Quality

74.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 25-89

PDB

Domain cluster: rep: IMGVR_UViG_2802429591_000002-2802429591-2805863766__D3-66

CATH (39)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1ncsA00	3.30.160.60	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger	0.71	44.0	4.99e-01	70.8%	87.2%
4l9cA00	3.40.1000.30	Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A ›	0.69	52.0	4.00e-01	81.5%	82.0%
2f51A00	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.68	48.0	4.01e-01	73.8%	99.1%
1z1bA01	3.30.160.60	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger	0.68	53.0	5.56e-01	92.3%	98.2%
2bn8A00	3.30.730.20	Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › Cell division activator CedA	0.68	49.0	4.91e-01	86.2%	76.1%
2ec4A00	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.66	49.0	3.69e-01	81.5%	83.0%
3cyjA01	3.30.390.10	Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain	0.63	48.0	4.04e-01	86.2%	75.4%
3cxgA00	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.63	44.0	3.67e-01	75.4%	57.4%
1cjyA01	2.60.40.150	Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain	0.60	42.0	3.44e-01	73.8%	86.5%
3r7wB02	3.30.450.190	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase ›	0.60	40.0	3.44e-01	70.8%	44.9%
2lstA00	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.59	51.0	4.15e-01	98.5%	100.0%
2l2mA00	3.30.160.20	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain ›	0.59	42.0	4.18e-01	75.4%	72.9%
4nehA01	2.130.10.130	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Integrin alpha, N-terminal	0.59	48.0	3.02e-01	93.8%	39.0%
1tk7A01	2.20.70.10	Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; ›	0.58	30.0	3.70e-01	86.2%	83.8%
4agiA00	2.120.10.70	Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin	0.58	47.0	3.13e-01	95.4%	60.5%
6k5gA01	3.40.50.1580	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain	0.57	41.0	2.77e-01	76.9%	98.1%
1a9xA06	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.57	41.0	2.83e-01	75.4%	73.9%
2pn1A03	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.56	39.0	3.27e-01	73.8%	96.7%
6qk7A01	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.56	47.0	3.05e-01	98.5%	26.8%
2pm6D01	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.56	45.0	2.97e-01	89.2%	28.6%
4dimA03	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.56	41.0	2.94e-01	80.0%	96.3%
4aezA00	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.56	44.0	2.93e-01	93.8%	76.4%
1k8kC00	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.54	44.0	2.76e-01	89.2%	21.2%
4l2iB00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.54	42.0	2.83e-01	84.6%	79.1%
3wkmB01	2.30.42.10	Mainly Beta › Roll › Pdz3 Domain › PDZ domain	0.54	36.0	3.21e-01	80.0%	47.9%
4iwxA03	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.54	36.0	3.06e-01	70.8%	65.8%
2zihC00	1.10.3630.10	Mainly Alpha › Orthogonal Bundle › yeast vps74-n-term truncation variant fold › yeast vps74-n-term truncation variant domain like	0.54	38.0	2.56e-01	75.4%	97.5%
5i47B03	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.53	36.0	3.21e-01	70.8%	66.3%
2ichA01	2.40.370.10	Mainly Beta › Beta Barrel › AttH-like fold › AttH-like domain	0.53	39.0	3.03e-01	84.6%	87.2%
1celA00	2.70.100.10	Mainly Beta › Distorted Sandwich › 1,4-Beta-D-Glucan Cellobiohydrolase I; Chain A › Glycoside hydrolase, family 7, domain	0.53	38.0	2.32e-01	76.9%	57.7%
1nr0A01	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.52	43.0	2.79e-01	90.8%	66.1%
4ecnA02	2.60.40.3540	Mainly Beta › Sandwich › Immunoglobulin-like › Domain of unknown function DUF4458	0.52	42.0	3.46e-01	89.2%	94.3%
4j87A00	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.52	41.0	2.78e-01	93.8%	57.3%
6gfaA02	3.30.30.30	Alpha Beta › 2-Layer Sandwich › Defensin A-like ›	0.52	33.0	3.44e-01	90.8%	71.4%
8eg0B01	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.52	41.0	2.69e-01	93.8%	49.7%
1u3eM01	3.90.75.20	Alpha Beta › Alpha-Beta Complex › Homing Intron 3 (I-Ppo) Encoded Endonuclease; Chain A ›	0.51	34.0	3.00e-01	92.3%	41.5%
4ghbA00	2.40.160.190	Mainly Beta › Beta Barrel › Porin ›	0.51	42.0	2.94e-01	100.0%	53.7%
4ckbD03	2.40.50.830	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) ›	0.51	41.0	3.44e-01	98.5%	64.9%
6u5vB07	3.30.1120.100	Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain ›	0.50	40.0	3.32e-01	92.3%	76.0%

ECOD (60)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3965886	252.2.1.0 ↗	a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like	0.81	54.0	6.21e-01	70.8%	100.0%
3331331	252.2.1.1 ↗	a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2	0.77	65.0	5.63e-01	92.3%	92.0%
3827127	252.2.1.0 ↗	a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like	0.77	64.0	5.63e-01	90.8%	94.7%
134360	252.2.1.3 ↗	a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_1	0.72	52.0	5.28e-01	80.0%	78.1%
3969097	4325.1.1.0 ↗	mixed a+b and a/b › YegP-like › YegP-like › YegP-like	0.71	52.0	5.87e-01	75.4%	100.0%
4028372	241.10.1.0 ↗	a+b two layers › Type III secretory system chaperone-like › GAS2 domain › GAS2 domain	0.71	38.0	3.64e-01	81.5%	45.3%
3467141	252.2.1.1 ↗	a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2	0.70	61.0	5.09e-01	95.4%	70.0%
3334492	252.2.1.0 ↗	a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like	0.70	62.0	5.84e-01	100.0%	100.0%
3801304	214.1.1.1 ↗	a+b two layers › SH2 › SH2 › SH2 › SH2	0.65	51.0	4.08e-01	87.7%	67.1%
3342974	2484.1.1.106 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF659	0.64	44.0	3.97e-01	70.8%	61.1%
3404508	5.1.4.0 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed	0.63	51.0	3.20e-01	89.2%	27.5%
3909529	2485.1.1.55 ↗	a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › FAF1	0.61	46.0	3.32e-01	81.5%	62.1%
3678841	330.1.1.1 ↗	a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm	0.61	42.0	3.83e-01	72.3%	54.1%
3788239	5.1.4.0 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed	0.61	48.0	3.15e-01	87.7%	29.2%
4028641	5.1.4.1 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40	0.59	51.0	2.90e-01	100.0%	25.2%
3501749	2011.2.1.1 ↗	a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PNP_UDP_1	0.59	43.0	2.83e-01	80.0%	79.4%
3798470	2011.2.1.0 ↗	a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like	0.59	43.0	2.88e-01	80.0%	84.2%
4539356	2484.1.1.1 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70	0.59	39.0	2.51e-01	70.8%	34.9%
3838342	3799.1.1.1 ↗	alpha bundles › SabA N-terminal extracellular adhesion domain › SabA N-terminal extracellular adhesion domain › SabA N-terminal extracellular adhesion domain › SabA_adhesion	0.58	44.0	2.62e-01	80.0%	25.4%
4145162	5.1.11.0 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 9-bladed	0.58	48.0	3.03e-01	92.3%	34.1%
None	—		0.58	48.0	3.00e-01	95.4%	48.6%
3738403	5.1.4.32 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Nucleoporin_N	0.57	44.0	2.69e-01	86.2%	23.7%
3403497	5.1.4.377 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR35_TULP_N	0.57	47.0	2.88e-01	93.8%	48.7%
3511087	5.1.4.36 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MMS1_N	0.57	45.0	2.81e-01	87.7%	28.6%
3977938	4312.1.1.0 ↗	a+b two layers › RelE-like › RelE-like › RelE-like	0.56	43.0	4.23e-01	87.7%	75.7%
3629696	5.1.4.0 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed	0.56	45.0	2.82e-01	86.2%	20.6%
3319893	330.1.1.1 ↗	a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm	0.56	41.0	3.64e-01	80.0%	90.0%
4017127	5.1.3.0 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed	0.56	46.0	3.12e-01	96.9%	46.1%
3555908	5.1.4.6 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40,ANAPC4_WD40	0.56	43.0	2.75e-01	86.2%	22.4%
3207356	10.1.1.22 ↗	beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › DUF1349	0.55	46.0	3.35e-01	96.9%	64.5%
3620047	5.1.4.377 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR35_TULP_N	0.55	46.0	3.02e-01	96.9%	36.7%
4208967	2011.2.1.3 ↗	a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › Pept_tRNA_hydro	0.55	46.0	3.39e-01	95.4%	92.6%
4211951	2.1.1.14 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RuvA_N	0.54	43.0	4.03e-01	87.7%	82.5%
4998606	375.1.1.0 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related	0.54	30.0	3.32e-01	78.5%	68.9%
3843979	5.1.4.1 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40	0.54	43.0	2.82e-01	93.8%	38.6%
4952024	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.54	42.0	3.41e-01	89.2%	65.7%
None	—		0.54	45.0	2.91e-01	96.9%	39.1%
3227422	5.1.4.313 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_BBS7	0.54	45.0	2.91e-01	96.9%	63.3%
3508001	5.1.4.1 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40	0.54	42.0	2.82e-01	95.4%	57.1%
4449501	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.53	40.0	3.46e-01	87.7%	74.2%
3399741	5.1.4.377 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR35_TULP_N	0.53	43.0	2.79e-01	93.8%	36.8%
4405336	206.1.3.21 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RimK	0.53	37.0	2.59e-01	72.3%	34.4%
5025694	2.1.1.287 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Zn_ribbon_TiaS	0.53	41.0	3.22e-01	89.2%	81.9%
3537300	5.1.4.313 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_BBS7	0.53	44.0	2.88e-01	96.9%	64.0%
4618792	5.1.4.307 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PF29630	0.53	43.0	2.67e-01	93.8%	38.2%
5008504	7575.1.1.2 ↗	a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like › Peptidase_C25	0.53	39.0	2.76e-01	83.1%	95.5%
3857554	5.1.4.0 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed	0.53	44.0	2.81e-01	100.0%	31.6%
4018043	5.1.4.6 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40,ANAPC4_WD40	0.52	42.0	2.82e-01	95.4%	61.0%
5077301	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.52	40.0	3.36e-01	89.2%	79.2%
3191093	7579.1.1.42 ↗	a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4	0.52	42.0	2.72e-01	100.0%	66.4%
4952930	2.21.1.0 ↗	beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB)	0.52	37.0	3.49e-01	78.5%	70.6%
None	—		0.52	42.0	2.64e-01	93.8%	26.2%
5050417	5.1.4.0 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed	0.51	41.0	2.68e-01	95.4%	36.7%
4017191	7579.1.1.6 ↗	a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1	0.51	41.0	2.71e-01	100.0%	42.5%
3927181	5.1.4.377 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR35_TULP_N	0.51	41.0	2.65e-01	95.4%	29.9%
3798352	5.1.4.0 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed	0.51	42.0	2.80e-01	100.0%	50.9%
4179590	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.51	36.0	3.10e-01	80.0%	51.7%
4575597	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.50	38.0	3.23e-01	89.2%	77.7%
4979493	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.50	36.0	3.12e-01	81.5%	53.3%
5064247	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.50	36.0	3.24e-01	80.0%	63.6%

D2 high residues 234-296

PDB

D3 high residues 321-386

PDB

Domain cluster: representative

CATH (79)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3oioA00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.77	60.0	5.02e-01	84.8%	54.5%
4u7bA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.76	45.0	5.48e-01	75.8%	100.0%
3nxcA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.76	58.0	4.19e-01	90.9%	30.5%
2o3fA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.75	60.0	5.57e-01	86.4%	79.3%
2cfxA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.75	52.0	5.89e-01	83.3%	96.0%
3lsgA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.74	56.0	5.98e-01	80.3%	100.0%
2k9sA00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.74	58.0	4.94e-01	84.8%	56.1%
2p5vA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	51.0	5.72e-01	81.8%	92.3%
5dukB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	51.0	5.15e-01	81.8%	71.6%
2hxiA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.74	58.0	5.95e-01	86.4%	92.2%
3oouA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.73	53.0	5.68e-01	81.8%	94.5%
3mklA00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.73	57.0	4.95e-01	86.4%	55.8%
3pasA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.72	58.0	4.11e-01	87.9%	31.6%
4pcqA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	49.0	5.54e-01	78.8%	94.0%
5fglA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.71	55.0	3.92e-01	93.9%	28.0%
2ia0A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	51.0	5.56e-01	83.3%	92.6%
4jykA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.71	53.0	5.57e-01	80.3%	93.1%
2llkA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.71	43.0	5.22e-01	95.5%	100.0%
5dajD00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.71	56.0	3.98e-01	87.9%	29.7%
4ivnA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	55.0	5.29e-01	86.4%	81.6%
2qwtA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.70	58.0	4.25e-01	92.4%	35.3%
6xiuA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.70	53.0	4.67e-01	84.8%	54.5%
2dbbB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.70	50.0	5.41e-01	83.3%	90.9%
3iwfB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.70	54.0	4.95e-01	86.4%	73.0%
3mn2A00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.69	53.0	4.56e-01	84.8%	53.7%
4g9yA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	56.0	4.44e-01	89.4%	52.2%
2r0qC02	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.69	42.0	4.51e-01	83.3%	72.7%
4ijaA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	53.0	5.46e-01	83.3%	98.4%
1u8bA02	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.68	53.0	5.48e-01	84.8%	91.8%
4a0zA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	48.0	5.07e-01	81.8%	83.1%
2e7xA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	49.0	5.37e-01	83.3%	96.2%
4wcgA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	53.0	5.51e-01	83.3%	96.7%
4kmfA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	52.0	5.42e-01	83.3%	96.8%
2qwwC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	55.0	4.32e-01	89.4%	47.1%
2l4mA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	52.0	5.15e-01	83.3%	88.4%
7l1iA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	54.0	4.16e-01	89.4%	46.4%
3bddD00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	54.0	4.34e-01	89.4%	47.7%
3w6vA00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.67	51.0	4.41e-01	86.4%	51.4%
1k6yA01	1.10.10.200	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain	0.67	41.0	4.70e-01	83.3%	89.1%
3e6mA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	54.0	4.18e-01	89.4%	46.6%
2rdpA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	53.0	4.22e-01	89.4%	48.6%
2qtqB00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.66	50.0	3.64e-01	93.9%	27.9%
1lnwF01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	55.0	4.48e-01	92.4%	53.2%
4yifF00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	53.0	4.26e-01	89.4%	50.0%
1zarA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	52.0	4.75e-01	89.4%	79.8%
3qkxB00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.65	51.0	3.79e-01	92.4%	32.0%
4rgxB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	55.0	4.34e-01	92.4%	46.3%
2pexA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	52.0	4.11e-01	87.9%	55.9%
1on2A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	52.0	5.12e-01	90.9%	90.3%
2wteA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	53.0	5.24e-01	92.4%	94.4%
2m8gX00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.65	43.0	4.23e-01	77.3%	64.3%
2nyxB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	54.0	4.21e-01	92.4%	49.3%
2fbiA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	53.0	4.24e-01	92.4%	54.4%
4rs8A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	53.0	4.92e-01	92.4%	86.9%
2o8xA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	42.0	4.41e-01	98.5%	75.4%
3vfzB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	43.0	4.45e-01	100.0%	76.2%
2g3bA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.63	52.0	3.81e-01	93.9%	63.6%
2dg7A00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.63	54.0	3.93e-01	98.5%	34.4%
1a04A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	48.0	4.52e-01	86.4%	68.8%
3bj6B00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	50.0	3.89e-01	89.4%	46.4%
2v57A00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.62	54.0	4.03e-01	98.5%	62.0%
2dg8D00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.62	51.0	3.83e-01	93.9%	65.3%
5zyrA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.62	51.0	3.98e-01	92.4%	41.7%
2cobA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.62	39.0	4.38e-01	86.4%	97.7%
2g7gA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.61	52.0	3.80e-01	98.5%	51.8%
4cgrB00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.61	53.0	3.84e-01	98.5%	58.1%
3hugA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	43.0	4.08e-01	98.5%	61.3%
3anpB00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.61	54.0	3.87e-01	100.0%	59.3%
4qicC01	1.20.140.160	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain	0.61	43.0	3.52e-01	100.0%	39.2%
4o5vA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	49.0	4.88e-01	93.9%	90.1%
3t0yA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.60	40.0	4.18e-01	98.5%	76.7%
6uglB02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.60	42.0	4.48e-01	81.8%	86.2%
1p4wA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	45.0	4.24e-01	89.4%	70.1%
1x4oA00	1.10.10.790	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module	0.57	43.0	4.15e-01	86.4%	70.5%
2ao9I01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.57	41.0	3.78e-01	86.4%	58.6%
3zh9B03	1.20.272.10	Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 ›	0.52	46.0	3.73e-01	98.5%	63.5%
1lliA00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.52	39.0	3.62e-01	83.3%	61.8%
7xi5A01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.50	32.0	3.45e-01	92.4%	82.4%
3pntA01	1.10.10.1660	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Nicotine adenine dinucleotide glycohydrolase, helical linker domain	0.50	38.0	3.69e-01	84.8%	77.3%

ECOD (96)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3961361	101.1.1.5 ↗	alpha arrays › HTH › HTH › Three-helical HTH › TetR_N	0.85	56.0	6.58e-01	77.3%	100.0%
3968724	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.82	60.0	5.76e-01	77.3%	69.3%
3970309	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.81	59.0	6.45e-01	77.3%	94.5%
3968456	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.80	62.0	5.24e-01	83.3%	52.8%
3970262	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.80	56.0	6.29e-01	72.7%	100.0%
3979732	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.79	58.0	5.90e-01	77.3%	81.5%
4535673	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.79	57.0	6.29e-01	78.8%	100.0%
4159676	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.79	57.0	6.15e-01	77.3%	98.2%
3941496	101.1.1.11 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_6	0.78	63.0	6.06e-01	87.9%	77.3%
3956897	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.77	61.0	5.18e-01	84.8%	55.2%
3923654	101.1.1.356 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_11	0.77	51.0	5.33e-01	77.3%	75.0%
4241379	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.77	57.0	6.07e-01	78.8%	98.2%
3944142	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.76	55.0	5.84e-01	80.3%	92.7%
3572145	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.76	50.0	5.46e-01	78.8%	81.8%
3976262	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.76	58.0	4.89e-01	86.4%	48.7%
4363165	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.75	58.0	5.91e-01	84.8%	90.8%
4368209	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.75	53.0	5.86e-01	78.8%	100.0%
1761205	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.75	55.0	5.92e-01	77.3%	100.0%
3289320	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.75	55.0	5.92e-01	78.8%	98.2%
3980379	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.75	58.0	4.90e-01	86.4%	50.5%
4576414	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.75	57.0	5.76e-01	81.8%	84.6%
3973662	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.75	58.0	5.08e-01	86.4%	56.0%
3277965	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.75	52.0	5.76e-01	77.3%	98.0%
3970742	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.75	56.0	6.01e-01	81.8%	100.0%
3279219	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.74	57.0	6.10e-01	83.3%	100.0%
3788384	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.74	58.0	4.90e-01	84.8%	59.6%
4004617	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.74	58.0	4.82e-01	84.8%	51.3%
4415767	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.74	56.0	5.69e-01	81.8%	86.2%
3590587	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.74	55.0	5.80e-01	81.8%	96.4%
4233016	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.74	57.0	6.12e-01	83.3%	100.0%
3986364	101.1.1.11 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_6	0.73	57.0	5.22e-01	86.4%	64.4%
3589353	101.1.1.11 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_6	0.73	58.0	5.33e-01	86.4%	72.9%
4544741	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.73	55.0	5.75e-01	84.8%	91.7%
3282057	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.73	55.0	5.40e-01	83.3%	77.1%
3286669	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.73	53.0	5.71e-01	78.8%	98.2%
4007690	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.73	52.0	5.54e-01	75.8%	96.4%
3946233	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.73	53.0	5.66e-01	78.8%	98.2%
3279234	101.1.1.11 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_6	0.72	56.0	5.56e-01	84.8%	91.4%
4034594	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.72	55.0	5.94e-01	83.3%	100.0%
3969207	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.72	56.0	5.41e-01	84.8%	77.3%
3972891	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.72	56.0	4.89e-01	86.4%	56.0%
3971324	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.72	55.0	5.75e-01	84.8%	96.7%
3952144	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.72	52.0	5.29e-01	83.3%	76.9%
4957813	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.72	51.0	5.18e-01	84.8%	75.4%
5027482	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	49.0	4.85e-01	83.3%	67.1%
4251046	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.72	54.0	5.61e-01	81.8%	95.0%
3942713	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.72	51.0	5.51e-01	78.8%	100.0%
3968277	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.72	55.0	5.93e-01	83.3%	100.0%
5046761	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	52.0	5.41e-01	83.3%	83.3%
4931184	101.1.2.140 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_AsnC-type	0.71	52.0	5.61e-01	83.3%	90.9%
3946981	101.1.2.140 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_AsnC-type	0.71	51.0	5.47e-01	84.8%	89.1%
3278092	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.71	54.0	5.49e-01	84.8%	89.2%
5030813	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.71	49.0	5.59e-01	80.3%	96.0%
4010472	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.71	49.0	5.54e-01	81.8%	96.0%
2670618	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.71	54.0	5.70e-01	81.8%	96.5%
4225050	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.71	51.0	5.65e-01	75.8%	100.0%
4962330	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.71	57.0	5.20e-01	100.0%	67.1%
4590066	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.71	54.0	4.60e-01	86.4%	49.6%
3288983	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.71	53.0	5.54e-01	83.3%	98.3%
3203415	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.70	60.0	5.60e-01	97.0%	96.5%
4943479	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.70	49.0	5.54e-01	80.3%	96.0%
3960513	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.70	52.0	5.59e-01	81.8%	100.0%
3975658	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.70	54.0	4.92e-01	84.8%	63.3%
4304527	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.70	53.0	5.49e-01	83.3%	95.0%
5058496	101.1.2.140 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_AsnC-type	0.69	50.0	4.93e-01	83.3%	71.4%
4967690	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.69	48.0	5.42e-01	80.3%	96.0%
3944639	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.69	52.0	4.52e-01	81.8%	54.8%
5030106	101.1.2.140 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_AsnC-type	0.69	50.0	5.40e-01	83.3%	90.9%
4944479	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.69	52.0	5.10e-01	95.5%	74.3%
4539758	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.69	54.0	4.48e-01	86.4%	49.2%
3286027	101.1.2.140 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_AsnC-type	0.69	50.0	5.20e-01	83.3%	83.3%
4610234	101.1.2.89 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_DeoR	0.69	48.0	4.98e-01	80.3%	80.0%
3971083	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.69	52.0	5.60e-01	83.3%	100.0%
3789307	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.68	57.0	5.68e-01	97.0%	100.0%
3945925	101.1.1.58 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_18	0.68	53.0	4.63e-01	84.8%	57.0%
3291169	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.68	52.0	5.55e-01	83.3%	100.0%
3284075	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.68	52.0	5.52e-01	83.3%	100.0%
4943799	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.68	48.0	5.37e-01	80.3%	98.0%
5030108	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.67	48.0	5.24e-01	84.8%	90.9%
3970819	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.67	51.0	5.34e-01	84.8%	98.3%
4557684	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.66	52.0	5.17e-01	89.4%	90.0%
4979724	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.66	51.0	5.23e-01	84.8%	84.6%
3277793	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.66	50.0	5.34e-01	83.3%	100.0%
3728726	101.1.1.2 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_AraC	0.65	49.0	4.79e-01	86.4%	77.3%
3282956	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.64	47.0	5.01e-01	81.8%	100.0%
4984666	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.63	54.0	5.16e-01	92.4%	97.3%
5040079	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.63	51.0	4.88e-01	86.4%	78.7%
3873677	101.1.1.24 ↗	alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N	0.63	43.0	4.23e-01	97.0%	65.7%
3727621	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.63	47.0	4.55e-01	86.4%	71.2%
4979728	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.61	51.0	4.72e-01	92.4%	76.5%
4962128	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.58	49.0	4.85e-01	92.4%	90.0%
5056682	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.57	44.0	4.34e-01	92.4%	80.0%
3606100	2004.1.1.74 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1,YGR210-like_G4	0.56	46.0	2.96e-01	93.9%	64.8%
3587045	5065.1.1.2 ↗	alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD	0.53	45.0	3.01e-01	100.0%	75.0%
3059487	101.1.4.3 ↗	alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_3	0.51	35.0	3.29e-01	83.3%	57.0%
3963888	5065.1.1.2 ↗	alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD	0.51	41.0	2.84e-01	100.0%	68.5%

D4 high residues 415-462

PDB

Domain cluster: representative

CATH (11)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5x68A00	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.69	59.0	3.54e-01	100.0%	90.9%
4efcA01	1.10.275.10	Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain)	0.66	51.0	3.89e-01	87.5%	70.2%
2oap202	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.64	53.0	3.33e-01	95.8%	97.8%
2e9yB00	3.40.1160.10	Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like	0.59	39.0	2.45e-01	70.8%	94.6%
4yzgA00	3.60.40.10	Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain	0.58	46.0	2.95e-01	100.0%	51.0%
2qhoD00	1.10.8.10	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain	0.57	44.0	4.42e-01	91.7%	85.7%
6xzqA01	3.40.91.90	Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain	0.56	42.0	2.97e-01	100.0%	23.5%
3u37A02	3.40.50.1110	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase	0.56	41.0	2.61e-01	77.1%	91.1%
2pvzB01	3.10.310.10	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1	0.56	47.0	3.13e-01	95.8%	95.6%
2qgaB01	1.10.275.10	Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain)	0.55	47.0	3.61e-01	100.0%	63.2%
4q5eA02	1.10.510.10	Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1	0.51	34.0	2.93e-01	72.9%	57.0%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4108185	210.1.1.1 ↗	a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome	0.63	54.0	3.75e-01	100.0%	27.4%
4945633	210.1.3.5 ↗	a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7	0.58	50.0	3.26e-01	100.0%	26.5%
3691454	2002.1.1.96 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › S-methyl_trans	0.57	39.0	2.38e-01	72.9%	90.3%
4014289	2485.1.1.0 ↗	a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like	0.56	46.0	3.33e-01	100.0%	78.1%
3274487	605.1.1.155 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Gpi1	0.56	42.0	3.01e-01	85.4%	74.9%
1527468	4.1.1.51 ↗	beta barrels › SH3 › SH3 › SH3 › SGF29_Tudor	0.53	42.0	3.24e-01	87.5%	47.7%
3234426	174.1.1.14 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › NKAIN	0.53	40.0	2.86e-01	83.3%	38.1%

D5 medium residues 99-162

PDB

Domain cluster: representative

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1mpgA02	1.10.340.30	Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2	0.58	39.0	3.30e-01	71.9%	99.2%
1vx7000	2.30.170.20	Mainly Beta › Roll › Ribosomal Protein L24e; Chain: T; › Ribosomal protein L24	0.55	33.0	3.36e-01	75.0%	58.1%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3984116	102.1.2.1 ↗	alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase › HhH-GPD	0.51	43.0	3.10e-01	96.9%	62.1%

D6 medium residues 173-233

PDB

Domain cluster: rep: IMGVR_UViG_3300031992_000232-3300031992-Ga0310694_100008201__D415-462

CATH (16)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4j31A00	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.71	57.0	3.52e-01	88.5%	94.5%
1umqA00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.63	37.0	3.81e-01	73.8%	60.0%
3lcvB01	1.10.8.10	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain	0.63	44.0	4.53e-01	73.8%	94.7%
1b9mB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	36.0	3.09e-01	78.7%	35.4%
4hasA00	3.30.1520.10	Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain	0.61	45.0	3.86e-01	82.0%	93.3%
3rm5B01	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.60	51.0	3.34e-01	100.0%	61.0%
2wzfA01	1.10.1740.130	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A ›	0.59	46.0	4.04e-01	91.8%	79.8%
2wm1A00	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.58	48.0	3.05e-01	91.8%	82.8%
2qgaB01	1.10.275.10	Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain)	0.57	44.0	3.60e-01	83.6%	71.1%
1ml8A01	2.20.25.10	Mainly Beta › Single Sheet › N-terminal domain of TfIIb ›	0.57	30.0	3.84e-01	82.0%	94.1%
1ufzA01	1.10.8.10	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain	0.56	44.0	4.47e-01	91.8%	91.4%
4efcA01	1.10.275.10	Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain)	0.56	43.0	3.46e-01	83.6%	72.7%
3fogA00	3.30.1520.10	Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain	0.55	40.0	3.50e-01	82.0%	93.1%
3k7dA01	1.20.120.1510	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.53	45.0	3.78e-01	100.0%	85.0%
3hz4A00	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.52	42.0	3.54e-01	96.7%	93.3%
3gjyA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.51	42.0	2.77e-01	95.1%	75.3%

ECOD (17)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
None	—		0.68	53.0	3.91e-01	86.9%	86.5%
3812213	2484.1.1.9 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve	0.67	52.0	3.88e-01	86.9%	86.7%
3981557	148.1.3.0 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain	0.67	52.0	4.93e-01	86.9%	97.3%
3502261	214.1.1.10 ↗	a+b two layers › SH2 › SH2 › SH2 › DUF7145	0.60	41.0	3.23e-01	72.1%	51.1%
4202176	220.1.1.123 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_SSH1-like_1st	0.58	40.0	2.87e-01	72.1%	28.9%
4992926	4009.1.1.0 ↗	alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins	0.58	41.0	3.87e-01	75.4%	86.7%
385833	277.1.1.1 ↗	a+b two layers › PX domain › PX domain › PX domain › PX	0.58	42.0	3.57e-01	78.7%	92.5%
222744	4952.1.1.0 ↗	alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like	0.56	43.0	3.43e-01	83.6%	70.4%
3450454	148.1.3.8 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › ClpB_D2-small	0.56	47.0	3.64e-01	96.7%	71.4%
3290645	2498.1.1.29 ↗	mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78	0.55	47.0	3.87e-01	100.0%	63.3%
4038683	103.1.1.5 ↗	alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › FmrO	0.55	46.0	4.66e-01	96.7%	95.0%
4067859	304.102.1.3 ↗	a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › PseudoU_synth_1	0.55	41.0	2.82e-01	83.6%	49.4%
3706176	2003.1.2.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain	0.53	43.0	2.91e-01	95.1%	79.6%
3475647	5.1.4.1 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40	0.53	46.0	3.11e-01	100.0%	28.8%
4451796	304.102.1.3 ↗	a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › PseudoU_synth_1	0.52	40.0	2.80e-01	90.2%	51.4%
3462514	2484.1.1.9 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve	0.52	44.0	3.20e-01	98.4%	90.0%
4275101	7523.1.1.45 ↗	a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Lipoprotein_X	0.52	40.0	2.67e-01	90.2%	56.8%