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IMGVR_UViG_3300032167_005879-3300032167-Ga0224413_101867305
Arc-VirIMGVR_UViG_3300032167_005879-3300032167-Ga0224413_101867305
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 46-118
Domain cluster:
representative
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4bzaA01 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.69 | 53.0 | 5.45e-01 | 97.3% | 89.7% |
| 4k3cA01 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.68 | 56.0 | 5.42e-01 | 93.2% | 85.4% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 54.0 | 4.89e-01 | 89.0% | 65.7% |
| 1gzmA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 49.0 | 3.17e-01 | 79.5% | 33.5% |
| 3dbaA00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.65 | 46.0 | 3.46e-01 | 74.0% | 100.0% |
| 2qdfA02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.65 | 53.0 | 5.18e-01 | 93.2% | 84.3% |
| 6j09A04 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.64 | 53.0 | 5.21e-01 | 93.2% | 87.0% |
| 1hlvA02 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.64 | 47.0 | 5.05e-01 | 84.9% | 93.3% |
| 1tigA00 | 3.30.110.10 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Translation initiation factor 3 (IF-3), C-terminal domain | 0.64 | 48.0 | 4.50e-01 | 100.0% | 65.9% |
| 6nplA01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.63 | 51.0 | 3.11e-01 | 89.0% | 65.7% |
| 2x6hA02 | 3.30.1010.10 | Alpha Beta › 2-Layer Sandwich › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 | 0.63 | 55.0 | 4.35e-01 | 100.0% | 57.3% |
| 6j09A02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.63 | 53.0 | 5.27e-01 | 97.3% | 88.5% |
| 7utzR02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 47.0 | 3.15e-01 | 79.5% | 43.2% |
| 5uayA02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.62 | 49.0 | 4.75e-01 | 97.3% | 78.3% |
| 1sz7A00 | 3.30.1380.20 | Alpha Beta › 2-Layer Sandwich › Muramoyl-pentapeptide Carboxypeptidase; domain 2 › Trafficking protein particle complex subunit 3 | 0.60 | 51.0 | 4.11e-01 | 100.0% | 64.8% |
| 6aveA01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.60 | 42.0 | 4.22e-01 | 97.3% | 73.0% |
| 5uayA01 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.60 | 48.0 | 4.63e-01 | 97.3% | 78.0% |
| 1gcbA01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.59 | 50.0 | 3.10e-01 | 91.8% | 48.5% |
| 3tf8B00 | 3.90.1520.10 | Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain | 0.59 | 50.0 | 3.77e-01 | 95.9% | 50.5% |
| 2dsiA02 | 3.30.950.10 | Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain | 0.59 | 48.0 | 3.87e-01 | 93.2% | 62.9% |
| 4k7cA01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.58 | 47.0 | 2.97e-01 | 90.4% | 49.5% |
| 1kblA05 | 1.20.80.30 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.57 | 43.0 | 4.06e-01 | 80.8% | 88.8% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 38.0 | 4.28e-01 | 100.0% | 98.0% |
| 2gsvA00 | 6.10.140.40 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 42.0 | 4.35e-01 | 82.2% | 100.0% |
| 2hxoA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 46.0 | 3.86e-01 | 95.9% | 92.4% |
| 2lu1A00 | 3.30.70.2370 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 43.0 | 4.10e-01 | 86.3% | 69.7% |
| 1cbyA00 | 3.40.198.10 | Alpha Beta › 3-Layer(aba) Sandwich › Delta-endotoxin CytB › Delta-endotoxin CytB-like | 0.55 | 47.0 | 3.35e-01 | 95.9% | 47.1% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.55 | 35.0 | 3.72e-01 | 100.0% | 75.4% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 42.0 | 3.87e-01 | 86.3% | 98.0% |
| 6g4gD01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.54 | 44.0 | 3.12e-01 | 90.4% | 83.9% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 42.0 | 3.76e-01 | 86.3% | 88.7% |
| 1bd3A00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 37.0 | 2.69e-01 | 98.6% | 23.2% |
| 7ewfA01 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 43.0 | 2.99e-01 | 89.0% | 30.7% |
| 2r7hB00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.52 | 45.0 | 3.59e-01 | 100.0% | 55.3% |
| 3r0qA02 | 2.70.160.11 | Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 | 0.52 | 43.0 | 3.20e-01 | 95.9% | 71.6% |
| 4v19W00 | 3.90.470.10 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 | 0.52 | 41.0 | 3.29e-01 | 91.8% | 76.5% |
| 3umgA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.52 | 41.0 | 4.16e-01 | 94.5% | 93.0% |
| 1av5A00 | 3.30.428.10 | Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like | 0.51 | 42.0 | 3.72e-01 | 94.5% | 77.9% |
| 3e98B00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.51 | 44.0 | 3.38e-01 | 98.6% | 74.1% |
| 2o61A03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 44.0 | 3.87e-01 | 100.0% | 75.5% |
| 2kwhA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 35.0 | 3.85e-01 | 100.0% | 94.6% |
| 3t5vA00 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.50 | 42.0 | 2.83e-01 | 94.5% | 98.7% |
ECOD (40)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3229126 | 864.1.1.0 ↗ | a+b two layers › DLC › DLC › DLC | 0.70 | 56.0 | 5.29e-01 | 87.7% | 93.3% |
| 4998094 | 873.1.1.0 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain | 0.67 | 54.0 | 4.22e-01 | 90.4% | 61.2% |
| 3660838 | 3121.1.1.12 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › GIL1_IRKI_C | 0.67 | 57.0 | 3.62e-01 | 100.0% | 19.0% |
| 4258146 | 3121.1.1.1 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA | 0.66 | 54.0 | 5.33e-01 | 93.2% | 83.7% |
| 3937690 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.66 | 49.0 | 3.24e-01 | 79.5% | 38.1% |
| 2547935 | 3121.1.1.1 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA | 0.65 | 54.0 | 5.16e-01 | 97.3% | 77.5% |
| 3783974 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.65 | 51.0 | 3.71e-01 | 86.3% | 57.1% |
| 2547933 | 3121.1.1.1 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA | 0.65 | 53.0 | 5.13e-01 | 93.2% | 83.5% |
| 3739367 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.64 | 49.0 | 4.07e-01 | 84.9% | 67.4% |
| 3233779 | 873.1.1.5 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › HNOB | 0.63 | 53.0 | 3.92e-01 | 94.5% | 48.2% |
| 3166208 | 3121.1.1.4 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA_TamA_1 | 0.63 | 53.0 | 5.17e-01 | 97.3% | 88.7% |
| 3222449 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.62 | 48.0 | 3.21e-01 | 83.6% | 42.5% |
| 3935704 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.62 | 48.0 | 3.03e-01 | 83.6% | 32.4% |
| 3321517 | 2007.2.3.9 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › PTPlike_phytase | 0.62 | 47.0 | 2.98e-01 | 82.2% | 51.5% |
| 3601580 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.62 | 53.0 | 3.49e-01 | 100.0% | 33.7% |
| 3636358 | 5055.1.1.0 ↗ | extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel | 0.61 | 42.0 | 4.38e-01 | 100.0% | 80.0% |
| 3475067 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.61 | 52.0 | 3.51e-01 | 100.0% | 56.7% |
| 3787128 | 109.4.1.654 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFB6 | 0.59 | 46.0 | 3.30e-01 | 86.3% | 34.8% |
| 3174060 | 7023.1.1.0 ↗ | alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein | 0.59 | 42.0 | 3.81e-01 | 76.7% | 58.1% |
| 3975782 | 7529.1.1.1 ↗ | a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › Macro | 0.59 | 45.0 | 3.17e-01 | 82.2% | 28.9% |
| 3241726 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.58 | 46.0 | 2.93e-01 | 84.9% | 67.0% |
| 4512924 | 101.1.21.0 ↗ | alpha arrays › HTH › HTH › HTH in T7 RNA polymerase | 0.57 | 45.0 | 3.26e-01 | 89.0% | 50.8% |
| 3595504 | 5076.1.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier | 0.57 | 43.0 | 2.88e-01 | 83.6% | 37.3% |
| 3222941 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.57 | 43.0 | 3.27e-01 | 100.0% | 32.4% |
| 3222603 | 210.1.1.1 ↗ | a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome | 0.57 | 48.0 | 3.50e-01 | 100.0% | 58.0% |
| 3304359 | 304.48.1.70 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Intron_maturas2 | 0.57 | 48.0 | 2.92e-01 | 94.5% | 27.1% |
| 3703430 | 4193.1.1.0 ↗ | alpha arrays › RUN domain › RUN domain › RUN domain | 0.56 | 38.0 | 2.95e-01 | 100.0% | 29.7% |
| 4022861 | 5076.1.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier | 0.55 | 47.0 | 3.24e-01 | 100.0% | 55.7% |
| 3575508 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.54 | 45.0 | 3.93e-01 | 94.5% | 68.7% |
| 3687002 | 148.1.1.7 ↗ | alpha arrays › Histone-like › Histone-related › Histone › TAF | 0.54 | 37.0 | 3.25e-01 | 83.6% | 46.1% |
| 4927828 | 328.1.1.0 ↗ | a+b two layers › IF3-like › AlbA-like › AlbA-like | 0.54 | 43.0 | 3.99e-01 | 97.3% | 68.0% |
| 3800977 | 5076.1.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier | 0.54 | 46.0 | 3.17e-01 | 100.0% | 53.6% |
| 3798489 | 164.1.1.0 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II | 0.53 | 42.0 | 3.78e-01 | 89.0% | 72.7% |
| 3971089 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.53 | 44.0 | 3.38e-01 | 100.0% | 58.0% |
| 3450050 | 7581.1.1.25 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › FAE1_CUT1_RppA, ACP_syn_III_C | 0.52 | 43.0 | 2.71e-01 | 97.3% | 23.9% |
| 3714751 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 43.0 | 3.00e-01 | 100.0% | 42.7% |
| 3234354 | 3352.1.1.12 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › Dpy19 | 0.52 | 42.0 | 2.64e-01 | 97.3% | 30.7% |
| 3356051 | 101.1.1.138 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › GeBP-like_DBD | 0.52 | 40.0 | 3.78e-01 | 86.3% | 97.8% |
| 4943269 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.51 | 41.0 | 3.01e-01 | 95.9% | 78.3% |
| 3908397 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.51 | 40.0 | 2.77e-01 | 100.0% | 23.6% |