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IMGVR_UViG_3300033141_000944-3300033141-Ga0366833_100713519
Arc-VirIMGVR_UViG_3300033141_000944-3300033141-Ga0366833_100713519
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-181
Domain cluster:
representative
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 38.0 | 4.83e-01 | 76.5% | 100.0% |
| 3fhnA04 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.64 | 39.0 | 4.43e-01 | 80.4% | 80.2% |
| 1c17M00 | 1.20.120.220 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A | 0.64 | 47.0 | 5.14e-01 | 100.0% | 95.8% |
| 1ldjA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.63 | 34.0 | 3.94e-01 | 72.6% | 71.2% |
| 4bwcA02 | 1.10.439.20 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 | 0.62 | 26.0 | 3.12e-01 | 82.1% | 56.4% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.62 | 31.0 | 3.87e-01 | 70.9% | 76.9% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.61 | 40.0 | 4.79e-01 | 79.3% | 100.0% |
| 4huqS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.61 | 35.0 | 3.72e-01 | 77.7% | 60.4% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.61 | 35.0 | 4.01e-01 | 100.0% | 74.8% |
| 3tp3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 41.0 | 4.44e-01 | 88.3% | 80.4% |
| 4bejB02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.61 | 55.0 | 5.18e-01 | 100.0% | 79.8% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 34.0 | 4.36e-01 | 73.2% | 99.0% |
| 2genA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 38.0 | 3.77e-01 | 92.7% | 62.2% |
| 4irnA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 31.0 | 3.73e-01 | 82.7% | 79.0% |
| 7sf8A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 36.0 | 3.28e-01 | 91.6% | 47.3% |
| 4nuuB02 | 1.20.58.830 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 36.0 | 4.27e-01 | 74.9% | 96.7% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 35.0 | 4.16e-01 | 75.4% | 94.2% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.54 | 27.0 | 3.32e-01 | 70.4% | 71.9% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.54 | 31.0 | 3.95e-01 | 77.1% | 98.1% |
| 3fmsA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.54 | 40.0 | 4.45e-01 | 92.2% | 97.9% |
| 2wdqC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.53 | 33.0 | 3.90e-01 | 84.4% | 90.1% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 31.0 | 3.89e-01 | 76.5% | 100.0% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.53 | 32.0 | 3.72e-01 | 100.0% | 84.0% |
| 3rwlA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.52 | 46.0 | 3.55e-01 | 95.0% | 63.9% |
| 1tqnA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.52 | 45.0 | 3.29e-01 | 90.5% | 67.5% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 37.0 | 3.46e-01 | 73.7% | 71.6% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 29.0 | 3.55e-01 | 70.4% | 88.2% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.51 | 33.0 | 3.56e-01 | 92.2% | 74.5% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 29.0 | 3.70e-01 | 73.2% | 98.0% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.50 | 27.0 | 3.52e-01 | 70.9% | 96.8% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3946757 | 601.19.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F | 0.74 | 61.0 | 5.59e-01 | 85.5% | 67.6% |
| 3165030 | 601.19.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F | 0.74 | 68.0 | 6.65e-01 | 99.4% | 90.3% |
| 3679306 | 2004.1.1.474 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynamin_N, MMR_HSR1 | 0.67 | 52.0 | 3.83e-01 | 81.6% | 32.5% |
| 3751117 | 109.4.1.937 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_EDRF1 | 0.66 | 34.0 | 3.48e-01 | 73.2% | 49.7% |
| 4390743 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.64 | 36.0 | 3.78e-01 | 79.3% | 58.8% |
| 3320610 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.62 | 43.0 | 4.79e-01 | 81.0% | 89.3% |
| 3924625 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.62 | 51.0 | 5.02e-01 | 97.2% | 81.5% |
| 3906129 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 33.0 | 3.85e-01 | 89.4% | 72.0% |
| 3382881 | 601.4.1.41 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Chloroplast_duf | 0.61 | 53.0 | 4.65e-01 | 92.2% | 82.7% |
| 5061319 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.61 | 34.0 | 4.08e-01 | 89.9% | 81.7% |
| 3740894 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 31.0 | 4.28e-01 | 73.2% | 97.8% |
| 3980912 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.60 | 38.0 | 4.59e-01 | 90.5% | 97.4% |
| 3964369 | 6108.1.1.8 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Phage_Mu_F | 0.60 | 51.0 | 4.60e-01 | 91.6% | 96.4% |
| 3935953 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.60 | 33.0 | 3.68e-01 | 70.4% | 67.4% |
| 3170239 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.60 | 29.0 | 4.06e-01 | 70.4% | 93.3% |
| 3982476 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.59 | 31.0 | 3.72e-01 | 100.0% | 73.3% |
| 3311288 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 35.0 | 3.76e-01 | 77.1% | 65.0% |
| 3387492 | 5076.2.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › EI24 | 0.58 | 42.0 | 3.83e-01 | 72.6% | 63.8% |
| 3743434 | 3542.1.1.3 ↗ | alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Peptidase_A22B | 0.57 | 41.0 | 3.57e-01 | 94.4% | 47.5% |
| 3235128 | 601.18.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Got1 | 0.56 | 36.0 | 4.18e-01 | 98.3% | 91.2% |
| 5047392 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.56 | 42.0 | 4.32e-01 | 90.5% | 80.6% |
| 3512534 | 1076.1.1.6 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › DUF2053 | 0.55 | 37.0 | 4.00e-01 | 94.4% | 79.3% |
| 3321413 | 601.16.1.8 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › DUF1218 | 0.54 | 42.0 | 4.30e-01 | 100.0% | 85.9% |
| 4023646 | 174.1.1.88 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7641 | 0.54 | 28.0 | 3.33e-01 | 72.6% | 71.2% |
| 4399436 | 601.54.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 | 0.52 | 27.0 | 3.07e-01 | 73.7% | 62.1% |
| 3896730 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 37.0 | 4.17e-01 | 71.5% | 94.1% |
| 3304016 | 601.16.1.8 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › DUF1218 | 0.52 | 40.0 | 4.09e-01 | 97.8% | 83.5% |
| 3696446 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.51 | 45.0 | 4.43e-01 | 98.3% | 88.2% |
| 3479700 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.51 | 34.0 | 3.97e-01 | 79.9% | 100.0% |
| 3765032 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.50 | 29.0 | 3.21e-01 | 72.1% | 67.6% |
D2
high
residues 200-280
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1xgsA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 40.0 | 4.17e-01 | 100.0% | 85.7% |
| 1epwA01 | 3.90.1240.10 | Alpha Beta › Alpha-Beta Complex › Zincin-like › "Metalloproteases (""zincins""), catalytic domain like" | 0.51 | 40.0 | 2.58e-01 | 87.7% | 56.8% |
| 1s6lA02 | 3.15.10.60 | Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › Alkylmercury lyase | 0.50 | 32.0 | 2.79e-01 | 98.8% | 39.5% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3964369 | 6108.1.1.8 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Phage_Mu_F | 0.72 | 48.0 | 3.38e-01 | 100.0% | 22.4% |
| 3946757 | 601.19.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F | 0.70 | 48.0 | 3.46e-01 | 100.0% | 25.3% |
| 3475182 | 4342.1.1.1 ↗ | alpha complex topology › Tex N-terminal region-like › Tex N-terminal region-like › Tex N-terminal region-like › Tex_central_region | 0.59 | 41.0 | 3.09e-01 | 100.0% | 29.5% |
| 3394320 | 178.1.1.2 ↗ | alpha arrays › SWIB/MDM2 domain › SWIB/MDM2 domain › SWIB/MDM2 domain › SWIB_eIF2D | 0.56 | 48.0 | 4.82e-01 | 97.5% | 96.5% |
| 4335282 | 4028.1.1.0 ↗ | beta barrels › Barrel domain in heme-dependent catalases › Barrel domain in heme-dependent catalases › Barrel domain in heme-dependent catalases | 0.51 | 43.0 | 2.92e-01 | 100.0% | 66.7% |