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IMGVR_UViG_3300033388_002469-3300033388-Ga0370355_10033591
Arc-VirIMGVR_UViG_3300033388_002469-3300033388-Ga0370355_10033591
Identity
- Kingdom:
- archaea
Quality
79.3
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 10-91
Domain cluster:
representative
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.70 | 52.0 | 4.35e-01 | 76.8% | 57.3% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 55.0 | 5.05e-01 | 84.1% | 93.3% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.68 | 53.0 | 4.36e-01 | 85.4% | 61.3% |
| 2ynqB00 | 1.25.40.680 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain | 0.68 | 44.0 | 3.55e-01 | 80.5% | 35.8% |
| 2ccyA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.65 | 49.0 | 4.24e-01 | 80.5% | 91.3% |
| 3dcfA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 57.0 | 4.80e-01 | 100.0% | 77.5% |
| 2m63A00 | 1.25.40.780 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.64 | 48.0 | 3.84e-01 | 84.1% | 41.4% |
| 4y6cA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 55.0 | 4.03e-01 | 95.1% | 38.7% |
| 4b94A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 55.0 | 4.63e-01 | 98.8% | 81.6% |
| 1vljA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.62 | 46.0 | 3.40e-01 | 78.0% | 59.2% |
| 1oe8A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 52.0 | 4.56e-01 | 92.7% | 75.8% |
| 3nyjA00 | 1.20.120.770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain | 0.62 | 50.0 | 3.85e-01 | 86.6% | 54.1% |
| 3n00A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.62 | 45.0 | 3.50e-01 | 76.8% | 86.4% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 49.0 | 4.00e-01 | 85.4% | 86.2% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.61 | 49.0 | 4.19e-01 | 85.4% | 69.0% |
| 1hciA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 46.0 | 3.97e-01 | 80.5% | 77.8% |
| 2fbnA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 48.0 | 3.94e-01 | 87.8% | 51.6% |
| 2np9A01 | 1.20.58.1300 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 50.0 | 4.23e-01 | 91.5% | 84.3% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.60 | 43.0 | 4.27e-01 | 85.4% | 72.4% |
| 3nrgA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 50.0 | 3.72e-01 | 93.9% | 53.9% |
| 6n7pX01 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 51.0 | 3.53e-01 | 98.8% | 37.8% |
| 7vepA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 48.0 | 3.37e-01 | 87.8% | 44.4% |
| 2qfcA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 50.0 | 3.42e-01 | 98.8% | 26.8% |
| 3rjvA02 | 1.25.40.740 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 39.0 | 4.34e-01 | 85.4% | 87.5% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 46.0 | 3.94e-01 | 86.6% | 84.4% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 43.0 | 4.33e-01 | 85.4% | 77.6% |
| 3lcnB00 | 1.10.340.40 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain | 0.57 | 45.0 | 4.25e-01 | 96.3% | 71.1% |
| 1wgwA00 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.57 | 41.0 | 3.93e-01 | 80.5% | 63.6% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.57 | 43.0 | 3.93e-01 | 80.5% | 89.0% |
| 2bnlC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 48.0 | 4.19e-01 | 98.8% | 75.4% |
| 7ml0M01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.56 | 44.0 | 4.42e-01 | 97.6% | 85.4% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.56 | 42.0 | 4.13e-01 | 80.5% | 82.8% |
| 2f07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 47.0 | 3.69e-01 | 98.8% | 78.6% |
| 8b9zK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 43.0 | 4.21e-01 | 84.1% | 79.1% |
| 3eslA02 | 1.25.40.930 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 44.0 | 3.95e-01 | 96.3% | 59.7% |
| 1sqgA01 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.56 | 45.0 | 3.87e-01 | 91.5% | 85.8% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.55 | 48.0 | 4.57e-01 | 100.0% | 91.1% |
| 3mekA04 | 1.25.40.970 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 44.0 | 4.47e-01 | 90.2% | 90.0% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 43.0 | 4.16e-01 | 84.1% | 79.1% |
| 2v57A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 47.0 | 3.76e-01 | 98.8% | 59.6% |
| 1hqoA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 46.0 | 3.99e-01 | 95.1% | 77.1% |
| 4rocA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.54 | 45.0 | 4.23e-01 | 100.0% | 74.8% |
| 4qicC01 | 1.20.140.160 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain | 0.54 | 47.0 | 4.13e-01 | 98.8% | 87.2% |
| 8h6rA01 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.53 | 46.0 | 4.55e-01 | 96.3% | 94.1% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.52 | 40.0 | 4.03e-01 | 89.0% | 98.8% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.52 | 44.0 | 3.94e-01 | 96.3% | 65.5% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 43.0 | 3.93e-01 | 98.8% | 77.0% |
| 3au4A01 | 1.25.40.530 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain | 0.50 | 42.0 | 3.35e-01 | 100.0% | 66.8% |
ECOD (53)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4660691 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.72 | 65.0 | 4.73e-01 | 100.0% | 44.2% |
| 3705127 | 509.1.1.0 ↗ | alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain | 0.71 | 62.0 | 5.96e-01 | 96.3% | 86.3% |
| 4337213 | 132.1.1.1 ↗ | alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding | 0.70 | 62.0 | 5.59e-01 | 97.6% | 87.6% |
| 3497519 | 109.4.1.148 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EST1_DNA_bind,EST1 | 0.68 | 61.0 | 3.65e-01 | 97.6% | 23.6% |
| 5001053 | 1075.1.1.67 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › 12TM_1 | 0.68 | 58.0 | 4.31e-01 | 95.1% | 68.8% |
| 5055126 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.68 | 61.0 | 4.64e-01 | 100.0% | 69.5% |
| 3689475 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.67 | 54.0 | 5.84e-01 | 85.4% | 100.0% |
| 3931153 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 51.0 | 3.87e-01 | 98.8% | 33.2% |
| 3917171 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 54.0 | 4.18e-01 | 86.6% | 70.9% |
| 4007848 | 3355.1.1.21 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_sulph_symp, CitMHS | 0.66 | 57.0 | 3.60e-01 | 98.8% | 68.5% |
| 5074685 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.65 | 58.0 | 4.74e-01 | 100.0% | 84.5% |
| 4948103 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.65 | 58.0 | 4.24e-01 | 100.0% | 58.7% |
| 4945250 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.65 | 58.0 | 4.41e-01 | 100.0% | 67.7% |
| 3700902 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.65 | 43.0 | 4.40e-01 | 100.0% | 70.0% |
| 4091316 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.64 | 56.0 | 3.52e-01 | 100.0% | 28.9% |
| 2492494 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.63 | 51.0 | 4.88e-01 | 89.0% | 75.5% |
| 5069645 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.63 | 56.0 | 3.72e-01 | 100.0% | 39.7% |
| 3897033 | 372.2.1.1 ↗ | a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU | 0.63 | 48.0 | 3.33e-01 | 81.7% | 43.2% |
| 3595958 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.63 | 51.0 | 5.22e-01 | 91.5% | 88.7% |
| 4984231 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.63 | 55.0 | 3.97e-01 | 100.0% | 54.7% |
| 3592028 | 109.4.1.218 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP | 0.63 | 53.0 | 4.07e-01 | 92.7% | 63.8% |
| 4352218 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.63 | 50.0 | 3.40e-01 | 87.8% | 43.0% |
| 3711742 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 53.0 | 4.70e-01 | 91.5% | 87.8% |
| 3212257 | 601.33.1.10 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › DUF19 | 0.62 | 50.0 | 4.60e-01 | 86.6% | 68.6% |
| 3475115 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 45.0 | 3.26e-01 | 78.0% | 69.4% |
| 4956683 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 47.0 | 4.43e-01 | 81.7% | 83.0% |
| None | — | 0.62 | 53.0 | 3.70e-01 | 96.3% | 28.9% | |
| 4002921 | 109.4.1.626 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRAPPC9-Trs120 | 0.61 | 54.0 | 3.89e-01 | 96.3% | 56.1% |
| 154406 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 54.0 | 4.56e-01 | 100.0% | 83.0% |
| 3063543 | 109.23.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54 | 0.61 | 53.0 | 4.57e-01 | 97.6% | 82.4% |
| 3275328 | 109.4.1.496 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec5 | 0.61 | 52.0 | 3.14e-01 | 100.0% | 20.3% |
| 4947400 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.61 | 48.0 | 4.03e-01 | 85.4% | 87.9% |
| 3433168 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 49.0 | 3.78e-01 | 87.8% | 38.9% |
| 3577476 | 109.4.1.514 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps54 | 0.61 | 52.0 | 4.19e-01 | 96.3% | 65.5% |
| 3509923 | 6103.1.1.0 ↗ | alpha bundles › Death domain-associated protein 6 histone binding domain › Death domain-associated protein 6 histone binding domain › Death domain-associated protein 6 histone binding domain | 0.60 | 54.0 | 4.04e-01 | 95.1% | 53.0% |
| 3623844 | 109.4.1.220 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SMG1 | 0.60 | 52.0 | 2.97e-01 | 96.3% | 16.4% |
| 4953696 | 3843.1.1.37 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2109 | 0.60 | 44.0 | 4.51e-01 | 90.2% | 81.2% |
| 3397857 | 568.1.1.0 ↗ | few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related | 0.59 | 44.0 | 3.35e-01 | 78.0% | 38.4% |
| 4232113 | 3355.1.1.21 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_sulph_symp, CitMHS | 0.59 | 50.0 | 3.21e-01 | 100.0% | 22.6% |
| 3544884 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.59 | 50.0 | 4.07e-01 | 92.7% | 58.0% |
| 4997657 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.58 | 49.0 | 3.82e-01 | 100.0% | 48.3% |
| 3176612 | 109.4.1.957 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TTI1_N | 0.58 | 49.0 | 3.19e-01 | 93.9% | 34.3% |
| 3785966 | 5059.1.1.34 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, Nuc_sug_transp | 0.57 | 48.0 | 3.20e-01 | 93.9% | 61.7% |
| 4183120 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.57 | 46.0 | 3.90e-01 | 91.5% | 85.5% |
| 3954859 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.56 | 48.0 | 3.90e-01 | 100.0% | 76.5% |
| 4840 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.56 | 45.0 | 3.88e-01 | 91.5% | 86.4% |
| 3856595 | 5001.1.1.43 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › V1R | 0.55 | 51.0 | 3.43e-01 | 100.0% | 56.2% |
| 3495121 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.55 | 44.0 | 4.08e-01 | 86.6% | 96.2% |
| 3269813 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.55 | 40.0 | 2.66e-01 | 74.4% | 36.3% |
| 4970804 | 613.1.1.0 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0.55 | 46.0 | 3.43e-01 | 100.0% | 51.6% |
| 4967708 | 613.1.1.0 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0.53 | 46.0 | 3.39e-01 | 100.0% | 41.3% |
| 4503349 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.52 | 45.0 | 3.37e-01 | 100.0% | 42.3% |
| 4617196 | 185.1.1.1 ↗ | alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › Tryp_alpha_amyl | 0.50 | 40.0 | 3.92e-01 | 87.8% | 95.6% |
D2
medium
residues 102-156
D3
medium
residues 168-240
Domain cluster:
representative
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4qs8A01 | 3.40.367.20 | Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › | 0.78 | 56.0 | 3.67e-01 | 75.3% | 19.6% |
| 3b0cW00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.72 | 51.0 | 5.15e-01 | 74.0% | 100.0% |
| 2p0tA01 | 1.10.60.30 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › PSPTO4464-like domains | 0.71 | 51.0 | 5.09e-01 | 100.0% | 73.7% |
| 1zk8B02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 57.0 | 4.74e-01 | 100.0% | 76.5% |
| 1kxpD04 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.65 | 52.0 | 5.15e-01 | 90.4% | 90.9% |
| 1iufA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.64 | 51.0 | 5.05e-01 | 87.7% | 96.1% |
| 2qibB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 54.0 | 3.99e-01 | 100.0% | 52.4% |
| 6epyA01 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.62 | 56.0 | 3.81e-01 | 100.0% | 70.7% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.62 | 54.0 | 4.60e-01 | 97.3% | 89.9% |
| 5t3wA00 | 1.20.120.1160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 50.0 | 4.13e-01 | 100.0% | 48.9% |
| 4b6iA00 | 1.20.120.1620 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 53.0 | 4.80e-01 | 97.3% | 91.0% |
| 2qw6D00 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.61 | 55.0 | 5.21e-01 | 100.0% | 95.3% |
| 7vevA01 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.60 | 54.0 | 3.72e-01 | 100.0% | 74.6% |
| 3zibC00 | 1.20.120.1620 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 52.0 | 4.75e-01 | 97.3% | 89.6% |
| 2yguC00 | 1.10.238.190 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › | 0.59 | 51.0 | 4.43e-01 | 100.0% | 63.6% |
| 3hl6A02 | 1.20.58.700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 51.0 | 4.43e-01 | 97.3% | 65.2% |
| 3feuA00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.59 | 45.0 | 3.47e-01 | 86.3% | 49.7% |
| 2b8iA00 | 1.20.1280.100 | Mainly Alpha › Up-down Bundle › Monooxygenase › Pas factor, saposin domain | 0.58 | 48.0 | 4.76e-01 | 98.6% | 94.8% |
| 1iqpA03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.57 | 50.0 | 4.65e-01 | 98.6% | 77.7% |
| 1irxA05 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.57 | 46.0 | 4.25e-01 | 89.0% | 80.6% |
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.56 | 50.0 | 3.94e-01 | 100.0% | 59.9% |
| 7s03A01 | 1.10.10.1450 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.56 | 37.0 | 4.14e-01 | 82.2% | 100.0% |
| 4cthA02 | 1.10.1380.10 | Mainly Alpha › Orthogonal Bundle › Neutral endopeptidase; domain 2 › Neutral endopeptidase , domain2 | 0.56 | 46.0 | 2.95e-01 | 91.8% | 54.8% |
| 1m4rB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 39.0 | 3.24e-01 | 75.3% | 97.9% |
| 6yttA01 | 1.10.8.190 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Carbon monoxide dehydrogenase alpha subunit. Chain M, domain 1 | 0.56 | 48.0 | 4.37e-01 | 97.3% | 89.0% |
| 2a0uB01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.55 | 45.0 | 3.54e-01 | 91.8% | 84.4% |
| 1t3qA02 | 1.10.150.120 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › [2Fe-2S]-binding domain | 0.55 | 39.0 | 3.87e-01 | 86.3% | 70.4% |
| 7smgD00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.54 | 39.0 | 3.21e-01 | 97.3% | 39.4% |
| 1u8bA02 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.54 | 37.0 | 3.91e-01 | 72.6% | 90.2% |
| 2vtyA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.53 | 48.0 | 3.80e-01 | 100.0% | 66.0% |
| 3bf7A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 46.0 | 3.18e-01 | 100.0% | 91.8% |
| 1wtyA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.51 | 44.0 | 3.83e-01 | 100.0% | 88.8% |
| 1ciiA03 | 1.10.490.30 | Mainly Alpha › Orthogonal Bundle › Globin-like › Colicin | 0.51 | 43.0 | 3.48e-01 | 100.0% | 69.4% |
| 1vkeB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.51 | 41.0 | 3.67e-01 | 87.7% | 78.2% |
| 4jmjA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.51 | 35.0 | 2.72e-01 | 72.6% | 88.4% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4276274 | 198.2.1.1 ↗ | alpha arrays › Saposin-like › Bacteriocin AS-48-related › Bacteriocin AS-48-related › Bacteriocin_IId | 0.66 | 46.0 | 4.83e-01 | 87.7% | 83.1% |
| 5039859 | 6035.1.1.0 ↗ | alpha bundles › Primase helical domain › Primase helical domain › Primase helical domain | 0.65 | 45.0 | 4.28e-01 | 74.0% | 77.8% |
| 2387840 | 5060.2.1.2 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Spore_III_AB | 0.63 | 56.0 | 4.60e-01 | 98.6% | 80.0% |
| 3221955 | 601.25.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain | 0.62 | 56.0 | 4.39e-01 | 100.0% | 60.4% |
| 4942190 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.62 | 44.0 | 4.18e-01 | 94.5% | 62.5% |
| 1063115 | 3368.1.1.1 ↗ | alpha bundles › Rap2b (SMA2266) › Rap2b (SMA2266) › Rap2b (SMA2266) › Tai4 | 0.60 | 52.0 | 4.75e-01 | 97.3% | 89.6% |
| 4972787 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.60 | 52.0 | 4.80e-01 | 97.3% | 84.2% |
| 4431938 | 507.1.1.7 ↗ | alpha arrays › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › PF30523 | 0.59 | 44.0 | 3.14e-01 | 78.1% | 97.1% |
| 5034596 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.58 | 43.0 | 3.58e-01 | 80.8% | 74.1% |
| 184529 | 198.3.1.1 ↗ | alpha arrays › Saposin-like › PAS factor › PAS factor › Pas_Saposin | 0.58 | 48.0 | 4.76e-01 | 98.6% | 94.8% |
| 3588075 | 606.1.1.0 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain | 0.57 | 45.0 | 3.68e-01 | 87.7% | 51.4% |
| 4381449 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.57 | 43.0 | 4.43e-01 | 83.6% | 90.0% |
| 3924758 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.55 | 40.0 | 3.96e-01 | 100.0% | 73.8% |
| 3936725 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.54 | 40.0 | 4.02e-01 | 100.0% | 78.7% |
| 3529289 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.54 | 41.0 | 4.08e-01 | 98.6% | 81.3% |
| 5024936 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.54 | 45.0 | 4.52e-01 | 98.6% | 96.0% |
| 3737899 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.53 | 40.0 | 3.97e-01 | 98.6% | 76.2% |
| 4971986 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.53 | 45.0 | 4.00e-01 | 100.0% | 64.5% |
| 3547922 | 3860.1.1.143 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › PF29854 | 0.53 | 44.0 | 3.78e-01 | 93.2% | 83.3% |
| 4474612 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.53 | 40.0 | 3.10e-01 | 93.2% | 33.9% |
| 4283426 | 101.8.1.2 ↗ | alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 | 0.53 | 40.0 | 3.18e-01 | 89.0% | 37.6% |
| 3927489 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.53 | 39.0 | 3.96e-01 | 100.0% | 81.3% |
| 4055691 | 563.1.1.0 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.52 | 39.0 | 3.52e-01 | 93.2% | 57.1% |
| 5078313 | 131.1.1.3 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD | 0.52 | 41.0 | 3.03e-01 | 87.7% | 44.9% |
| 3925588 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.52 | 39.0 | 3.91e-01 | 98.6% | 81.3% |
| 4958329 | 601.7.1.34 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 | 0.51 | 44.0 | 3.96e-01 | 100.0% | 90.5% |
| 5078612 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.51 | 44.0 | 3.59e-01 | 98.6% | 77.0% |
| 4974395 | 601.7.1.34 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 | 0.50 | 42.0 | 3.89e-01 | 97.3% | 98.0% |
| 157755 | 601.7.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › NTase_sub_bind | 0.50 | 44.0 | 3.80e-01 | 100.0% | 95.0% |
| 4022703 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.50 | 42.0 | 3.82e-01 | 90.4% | 91.6% |
D4
medium
residues 404-467
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3u4qA02 | 1.10.274.50 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › | 0.80 | 57.0 | 4.29e-01 | 75.0% | 80.7% |
| 4hiaA00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.76 | 52.0 | 3.74e-01 | 71.9% | 27.8% |
| 1tfeA02 | 1.10.286.20 | Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › | 0.74 | 50.0 | 5.68e-01 | 71.9% | 100.0% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.73 | 53.0 | 4.86e-01 | 92.2% | 60.5% |
| 6mh4A03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.70 | 48.0 | 4.48e-01 | 71.9% | 57.0% |
| 1v1aA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.70 | 48.0 | 3.09e-01 | 71.9% | 63.1% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.69 | 49.0 | 4.38e-01 | 73.4% | 53.4% |
| 3qnmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.68 | 49.0 | 4.37e-01 | 81.2% | 54.4% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.68 | 48.0 | 4.44e-01 | 75.0% | 59.3% |
| 2pkeA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.67 | 46.0 | 4.35e-01 | 92.2% | 59.0% |
| 2gslF00 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.63 | 50.0 | 3.98e-01 | 85.9% | 61.4% |
| 2ebiA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.61 | 39.0 | 3.90e-01 | 71.9% | 62.1% |
| 1r6bX03 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.60 | 42.0 | 3.84e-01 | 73.4% | 56.8% |
| 5z9iA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.59 | 49.0 | 3.12e-01 | 98.4% | 34.7% |
| 4k08A00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.58 | 39.0 | 3.05e-01 | 73.4% | 31.2% |
| 3b4qA00 | 1.10.1200.100 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › conserved protein domain from corynebacterium diphtheriae | 0.57 | 45.0 | 4.11e-01 | 98.4% | 64.4% |
| 2lrmA00 | 1.10.890.30 | Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › YmgD protein | 0.55 | 39.0 | 3.65e-01 | 76.6% | 58.3% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.53 | 38.0 | 3.28e-01 | 79.7% | 48.2% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 43.0 | 3.11e-01 | 92.2% | 61.4% |
| 1eblA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.52 | 36.0 | 2.85e-01 | 73.4% | 68.7% |
| 3c8tA01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.52 | 39.0 | 3.44e-01 | 81.2% | 56.7% |
| 3cx3B01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.51 | 43.0 | 3.24e-01 | 92.2% | 82.5% |
| 6k9pB02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.51 | 39.0 | 3.08e-01 | 85.9% | 37.5% |
| 2itbB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 43.0 | 3.13e-01 | 100.0% | 72.7% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3597291 | 103.9.1.0 ↗ | alpha arrays › RuvA-C › RanGAP2 N-terminal domain › RanGAP2 N-terminal domain | 0.85 | 61.0 | 5.48e-01 | 75.0% | 56.5% |
| 4940509 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.84 | 58.0 | 4.92e-01 | 73.4% | 46.0% |
| 4941346 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.83 | 60.0 | 5.63e-01 | 75.0% | 69.3% |
| 4977883 | 6058.1.1.0 ↗ | alpha arrays › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase | 0.78 | 51.0 | 3.92e-01 | 70.3% | 30.7% |
| 4013825 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.78 | 53.0 | 5.00e-01 | 70.3% | 60.0% |
| 3934946 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.77 | 55.0 | 3.77e-01 | 76.6% | 79.6% |
| 3390061 | 5063.1.1.22 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › LIN9_C | 0.76 | 64.0 | 5.24e-01 | 90.6% | 84.5% |
| 3698416 | 844.1.1.0 ↗ | beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain | 0.75 | 55.0 | 3.69e-01 | 78.1% | 34.6% |
| 4170537 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.75 | 62.0 | 4.93e-01 | 92.2% | 50.8% |
| 3515411 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.74 | 53.0 | 3.70e-01 | 75.0% | 26.3% |
| 3181588 | 2004.1.1.366 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NPHP3_N | 0.74 | 50.0 | 3.28e-01 | 70.3% | 16.7% |
| None | — | 0.74 | 50.0 | 3.40e-01 | 71.9% | 20.0% | |
| 3739839 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.73 | 53.0 | 4.40e-01 | 76.6% | 73.6% |
| 4937236 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.73 | 59.0 | 5.11e-01 | 89.1% | 72.0% |
| 5079588 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.72 | 51.0 | 4.55e-01 | 73.4% | 56.7% |
| 4149728 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.72 | 52.0 | 4.80e-01 | 75.0% | 61.3% |
| 3589830 | 5043.2.1.8 ↗ | extended segments › Sensor proteins transmembrane domains › NarQ transmembrane domain › NarQ transmembrane domain › DUF5592 | 0.71 | 48.0 | 4.73e-01 | 70.3% | 72.9% |
| 4623986 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.69 | 51.0 | 3.39e-01 | 78.1% | 21.2% |
| 4478129 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.69 | 50.0 | 4.46e-01 | 75.0% | 52.2% |
| 1154557 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.68 | 53.0 | 4.64e-01 | 85.9% | 66.3% |
| 3392260 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.67 | 51.0 | 4.97e-01 | 79.7% | 78.6% |
| 3803646 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.65 | 43.0 | 4.38e-01 | 70.3% | 67.7% |
| 3453796 | 7519.1.1.11 ↗ | a/b three-layered sandwiches › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › Rick_17kDa_Anti, PF29034 | 0.63 | 47.0 | 4.04e-01 | 79.7% | 56.2% |
| 3312431 | 101.1.1.121 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_3 | 0.63 | 43.0 | 3.54e-01 | 81.2% | 37.6% |
| 3242517 | 4009.1.1.3 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › KTI12 | 0.62 | 43.0 | 4.15e-01 | 73.4% | 62.7% |
| 3874750 | 101.1.1.249 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › SGIII | 0.62 | 46.0 | 4.27e-01 | 79.7% | 83.7% |
| 3798302 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.57 | 37.0 | 3.59e-01 | 70.3% | 57.1% |
| 3969668 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.57 | 42.0 | 2.92e-01 | 81.2% | 37.0% |
| 4318142 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.56 | 48.0 | 3.82e-01 | 100.0% | 47.1% |
| 5067572 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.52 | 38.0 | 3.26e-01 | 79.7% | 57.1% |
D5
medium
residues 468-543
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8e9gK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 47.0 | 4.46e-01 | 73.7% | 68.1% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 50.0 | 4.46e-01 | 88.2% | 81.2% |
| 2lhrA00 | 1.20.58.1270 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 40.0 | 3.98e-01 | 90.8% | 65.4% |
| 3n8hA02 | 3.30.1300.10 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › Pantoate-beta-alanine ligase, C-terminal domain | 0.55 | 38.0 | 3.82e-01 | 100.0% | 72.4% |
| 1eupA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.52 | 44.0 | 2.89e-01 | 100.0% | 58.3% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3566571 | 109.25.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A | 0.58 | 43.0 | 4.20e-01 | 97.4% | 71.8% |
| 3940135 | 140.1.1.5 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 | 0.53 | 44.0 | 3.25e-01 | 94.7% | 55.5% |
| 3775067 | 198.1.1.21 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapA, SapB_2 | 0.51 | 35.0 | 3.14e-01 | 73.7% | 46.7% |
| 3560235 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.51 | 43.0 | 2.69e-01 | 100.0% | 50.1% |
D6
medium
residues 554-739
Domain cluster:
rep: GU071102.1__ADP00138.1__CYIG_00065__00062__D1160-1251_1340-1384
D7
medium
residues 768-850
Domain cluster:
representative
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3umbA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.75 | 55.0 | 5.65e-01 | 91.6% | 81.0% |
| 4akgA08 | 1.10.472.130 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain | 0.71 | 63.0 | 5.04e-01 | 96.4% | 53.8% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.69 | 45.0 | 4.34e-01 | 73.5% | 57.7% |
| 3q23A08 | 1.20.140.110 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.66 | 49.0 | 3.95e-01 | 77.1% | 81.2% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.64 | 42.0 | 4.60e-01 | 71.1% | 82.4% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.63 | 42.0 | 4.31e-01 | 79.5% | 71.8% |
| 4iw9A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 43.0 | 3.91e-01 | 72.3% | 55.8% |
| 4j8dD00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 35.0 | 2.78e-01 | 79.5% | 28.4% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.61 | 44.0 | 4.00e-01 | 74.7% | 60.9% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.61 | 34.0 | 4.46e-01 | 71.1% | 95.9% |
| 2ra1A02 | 1.20.58.780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 38.0 | 4.09e-01 | 73.5% | 77.9% |
| 2wdqC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.59 | 52.0 | 4.59e-01 | 97.6% | 89.3% |
| 4g6dB02 | 6.10.140.1800 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 42.0 | 4.33e-01 | 75.9% | 87.7% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.59 | 43.0 | 3.59e-01 | 78.3% | 98.0% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.58 | 43.0 | 3.82e-01 | 77.1% | 73.5% |
| 6oi7A01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.58 | 49.0 | 3.76e-01 | 94.0% | 45.4% |
| 2af7D00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.57 | 35.0 | 3.16e-01 | 90.4% | 42.1% |
| 4uyeA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.56 | 41.0 | 3.71e-01 | 75.9% | 96.3% |
| 2gmyD00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.56 | 43.0 | 3.54e-01 | 80.7% | 94.5% |
| 2fh5A01 | 3.30.450.60 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.56 | 48.0 | 4.27e-01 | 95.2% | 90.2% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 40.0 | 3.45e-01 | 74.7% | 52.3% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.56 | 38.0 | 3.19e-01 | 71.1% | 76.7% |
| 3pe0A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 40.0 | 3.73e-01 | 74.7% | 71.3% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.55 | 40.0 | 3.70e-01 | 77.1% | 66.4% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.55 | 42.0 | 3.32e-01 | 81.9% | 93.2% |
| 3lszA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 39.0 | 3.48e-01 | 77.1% | 51.2% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 41.0 | 3.48e-01 | 81.9% | 65.0% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 41.0 | 3.74e-01 | 79.5% | 70.4% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.54 | 48.0 | 4.41e-01 | 100.0% | 81.5% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.53 | 37.0 | 3.94e-01 | 75.9% | 80.3% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.53 | 39.0 | 4.18e-01 | 81.9% | 90.1% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.52 | 40.0 | 4.25e-01 | 81.9% | 98.6% |
| 1bhaA00 | 1.10.287.170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 38.0 | 4.18e-01 | 84.3% | 95.5% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 38.0 | 3.50e-01 | 79.5% | 69.6% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5078040 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.84 | 57.0 | 5.70e-01 | 74.7% | 68.2% |
| 3603732 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.80 | 56.0 | 6.23e-01 | 73.5% | 100.0% |
| 3362279 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.77 | 58.0 | 5.98e-01 | 79.5% | 82.5% |
| 3497236 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.77 | 57.0 | 3.85e-01 | 77.1% | 22.5% |
| 4050521 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.76 | 55.0 | 5.14e-01 | 75.9% | 61.2% |
| 3539986 | 5058.1.1.90 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › TMEM169 | 0.75 | 56.0 | 5.85e-01 | 77.1% | 96.0% |
| 3182867 | 2006.1.4.33 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › Tim17 | 0.73 | 51.0 | 5.27e-01 | 77.1% | 76.2% |
| 3191826 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.71 | 48.0 | 4.85e-01 | 74.7% | 69.4% |
| 4326931 | 207.1.1.386 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › NEL | 0.70 | 56.0 | 3.37e-01 | 88.0% | 28.6% |
| 3770340 | 5041.1.1.2 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM169 | 0.70 | 51.0 | 4.71e-01 | 75.9% | 73.3% |
| 4951179 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.70 | 48.0 | 4.53e-01 | 73.5% | 59.0% |
| 3210238 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.70 | 59.0 | 3.93e-01 | 90.4% | 71.8% |
| 5053609 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.68 | 62.0 | 5.27e-01 | 98.8% | 76.2% |
| 4939550 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.68 | 47.0 | 4.49e-01 | 75.9% | 62.1% |
| 3623555 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.68 | 62.0 | 4.98e-01 | 100.0% | 71.6% |
| 3475121 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.67 | 62.0 | 4.77e-01 | 100.0% | 66.3% |
| 5034026 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.67 | 47.0 | 4.36e-01 | 74.7% | 57.1% |
| 3221336 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.66 | 61.0 | 4.38e-01 | 100.0% | 50.9% |
| 5027915 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.66 | 50.0 | 5.20e-01 | 79.5% | 94.7% |
| 3970460 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.66 | 48.0 | 4.36e-01 | 77.1% | 64.3% |
| 3731914 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 46.0 | 3.93e-01 | 73.5% | 52.9% |
| 5058468 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.66 | 46.0 | 4.87e-01 | 74.7% | 81.3% |
| 5034349 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.65 | 55.0 | 5.10e-01 | 92.8% | 75.0% |
| 4157096 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.65 | 48.0 | 4.70e-01 | 77.1% | 77.8% |
| 5072135 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.65 | 54.0 | 4.11e-01 | 91.6% | 62.1% |
| 3578405 | 605.1.1.239 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › 7TM_GPCR_Srsx | 0.64 | 46.0 | 4.35e-01 | 75.9% | 64.0% |
| 4962910 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.64 | 56.0 | 4.75e-01 | 97.6% | 91.9% |
| 3221905 | 5001.1.1.54 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srbc | 0.63 | 55.0 | 4.45e-01 | 96.4% | 61.9% |
| 3164721 | 1078.1.1.0 ↗ | extended segments › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit | 0.63 | 45.0 | 4.44e-01 | 75.9% | 72.2% |
| 4937584 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.63 | 44.0 | 4.59e-01 | 73.5% | 82.7% |
| 3285853 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.63 | 57.0 | 5.21e-01 | 100.0% | 83.6% |
| 3331225 | 5042.1.1.0 ↗ | extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region | 0.63 | 45.0 | 4.77e-01 | 74.7% | 90.0% |
| 3289973 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.62 | 55.0 | 4.71e-01 | 100.0% | 85.2% |
| 5012157 | 605.1.1.354 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › MS_channel_1st_1 | 0.62 | 45.0 | 4.48e-01 | 75.9% | 74.1% |
| 5074821 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.62 | 48.0 | 4.02e-01 | 83.1% | 53.1% |
| 3909100 | 2004.1.1.118 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 | 0.62 | 45.0 | 3.15e-01 | 78.3% | 60.3% |
| 3238445 | 7525.1.1.2 ↗ | a/b three-layered sandwiches › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › His_Phos_2 | 0.62 | 49.0 | 3.30e-01 | 88.0% | 33.4% |
| 3590014 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.61 | 42.0 | 4.91e-01 | 75.9% | 100.0% |
| 5018642 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.59 | 44.0 | 4.11e-01 | 79.5% | 64.8% |
| 5066143 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.59 | 48.0 | 4.98e-01 | 88.0% | 100.0% |
| 5067494 | 3457.1.1.1 ↗ | alpha bundles › GxGD membrane protease › GxGD membrane protease › GxGD membrane protease › Peptidase_A24 | 0.59 | 48.0 | 3.92e-01 | 91.6% | 64.8% |
| 3185674 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.58 | 47.0 | 3.26e-01 | 90.4% | 80.0% |
| 4970788 | 4333.1.1.0 ↗ | a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain | 0.57 | 48.0 | 3.39e-01 | 95.2% | 83.9% |
| 3631798 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.56 | 45.0 | 3.14e-01 | 85.5% | 53.1% |
| 5047389 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.54 | 44.0 | 3.84e-01 | 89.2% | 93.8% |
| 3329547 | 604.6.1.22 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 | 0.54 | 39.0 | 3.56e-01 | 73.5% | 59.1% |
| 4929528 | 3684.1.1.56 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › AmoC | 0.54 | 43.0 | 3.55e-01 | 85.5% | 91.3% |
| 3268588 | 604.6.1.22 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 | 0.54 | 41.0 | 3.76e-01 | 81.9% | 63.6% |
| 3917631 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.52 | 39.0 | 3.60e-01 | 79.5% | 70.9% |
| 4015375 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 32.0 | 2.40e-01 | 72.3% | 22.1% |