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IMGVR_UViG_3300033463_000002-3300033463-Ga0310690_10000036264

Arc-Vir

IMGVR_UViG_3300033463_000002-3300033463-Ga0310690_10000036264

Quality

93.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-77
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14393.12 best DUF4422 31.2 2.80e-07 98.7% 33.6%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pg3A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.63 55.0 4.00e-01 100.0% 50.9%
2hxvA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.63 55.0 4.08e-01 98.6% 48.5%
4ha7B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.63 53.0 3.98e-01 98.6% 43.9%
6tdxG01 3.40.1380.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › ATP synthase, F1 complex, gamma subunit 0.62 54.0 3.96e-01 100.0% 42.1%
6kv9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.60 48.0 3.60e-01 100.0% 33.8%
3k2hA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.60 47.0 3.57e-01 100.0% 34.8%
7fg9A01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.60 50.0 3.93e-01 98.6% 52.8%
3douA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 50.0 3.89e-01 100.0% 41.1%
1uqtA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.59 50.0 3.59e-01 100.0% 60.9%
2fwmX00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 47.0 3.59e-01 100.0% 82.1%
1u02A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.57 49.0 3.96e-01 100.0% 90.8%
3aw9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 47.0 3.66e-01 100.0% 54.1%
2dt5A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 46.0 3.90e-01 98.6% 65.9%
2xyqA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 46.0 3.24e-01 98.6% 35.5%
4akfA01 3.40.1090.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytosolic phospholipase A2 catalytic domain › Cytosolic phospholipase A2 catalytic domain 0.55 46.0 3.12e-01 100.0% 80.2%
1im8B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 49.0 3.50e-01 100.0% 33.6%
3skvA02 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.55 43.0 3.29e-01 90.5% 67.0%
1j09A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 47.0 4.08e-01 100.0% 73.6%
5gqsA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 44.0 4.18e-01 91.9% 100.0%
5nnnA02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.53 44.0 3.64e-01 100.0% 71.1%
4d3pA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.53 44.0 3.68e-01 98.6% 78.9%
2ayxA01 3.40.50.10970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 42.0 3.72e-01 91.9% 84.2%
2g6zA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.50 41.0 3.50e-01 100.0% 56.5%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3308635 7516.1.1.0 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases 0.82 76.0 4.96e-01 100.0% 29.0%
3706735 7516.1.1.12 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Fringe 0.76 66.0 4.31e-01 100.0% 34.1%
4803833 331.3.1.41 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › DUF4422 0.75 65.0 6.65e-01 93.2% 97.2%
4630267 7516.1.1.89 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › HPAT 0.73 65.0 4.26e-01 100.0% 31.1%
5036171 7518.1.1.0 a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like 0.72 64.0 5.47e-01 100.0% 78.3%
3665992 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.65 57.0 4.18e-01 98.6% 51.5%
4959153 7518.1.1.6 a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › DacZ_A 0.65 56.0 4.82e-01 100.0% 70.4%
4973154 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.65 56.0 4.16e-01 100.0% 56.1%
4952969 7509.1.1.1 a/b three-layered sandwiches › NIF3 (NGG1p interacting factor 3)-like › NIF3 (NGG1p interacting factor 3)-like › NIF3 (NGG1p interacting factor 3)-like › DUF34_NIF3 0.64 52.0 4.71e-01 100.0% 64.8%
5007602 2003.1.1.28 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.64 52.0 4.43e-01 100.0% 53.6%
3927898 2003.1.10.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.63 55.0 4.88e-01 100.0% 76.4%
5061012 7512.1.1.31 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 0.63 53.0 4.06e-01 98.6% 50.5%
5011926 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.63 47.0 3.80e-01 90.5% 41.4%
169836 2005.1.1.3 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.62 54.0 4.30e-01 100.0% 71.2%
4956548 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.62 54.0 4.16e-01 100.0% 48.6%
4543836 7512.1.1.10 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_28 0.61 53.0 4.16e-01 100.0% 52.4%
5012331 7518.1.1.7 a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › DacZ_T 0.61 53.0 4.85e-01 100.0% 74.0%
5063987 300.1.1.8 a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › PLDc_2 0.60 48.0 3.95e-01 91.9% 76.7%
2845916 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.60 50.0 4.04e-01 98.6% 57.4%
5024560 2003.1.5.15 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.59 50.0 3.77e-01 100.0% 36.9%
3784976 2003.1.5.15 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.59 49.0 3.45e-01 98.6% 53.9%
5069572 2004.1.1.146 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.59 51.0 3.69e-01 100.0% 36.2%
4461157 1160.1.1.1 beta duplicates or obligate multimers › Endoglin orphan region (OR) domain › Endoglin orphan region (OR) domain › Endoglin orphan region (OR) domain › TGFBR3_N 0.59 51.0 4.05e-01 100.0% 48.1%
None 0.58 47.0 3.41e-01 98.6% 43.1%
5053140 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.57 47.0 3.67e-01 98.6% 45.3%
4512900 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.55 46.0 3.87e-01 97.3% 69.6%
5010068 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 35.0 2.45e-01 83.8% 18.5%
4025473 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.53 44.0 3.47e-01 100.0% 48.3%
4183099 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.50 42.0 3.31e-01 100.0% 43.9%
D2 high residues 99-233
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14393.12 best DUF4422 64.5 1.90e-17 74.1% 40.5%
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.57 28.0 3.56e-01 75.6% 78.0%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.56 28.0 3.35e-01 100.0% 71.1%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.56 35.0 4.09e-01 91.1% 92.4%
1i36A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.53 28.0 3.19e-01 94.8% 65.7%
5mlc900 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.52 37.0 4.09e-01 88.9% 92.5%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.52 34.0 3.81e-01 89.6% 84.9%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.51 37.0 4.08e-01 89.6% 92.7%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 32.0 3.47e-01 80.7% 77.8%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4329065 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.61 37.0 4.52e-01 94.8% 95.3%
3999587 3755.4.1.48 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › V_ATPase_I 0.55 26.0 2.50e-01 100.0% 36.1%
3856007 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.55 38.0 3.12e-01 100.0% 37.6%
3551542 873.1.1.5 a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › HNOB 0.55 41.0 3.74e-01 80.0% 70.0%
3284767 164.1.1.1 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 0.53 34.0 3.19e-01 92.6% 51.5%
3935662 601.26.1.3 alpha bundles › Four-helical up-and-down bundle › YppE-like › YppE-like › TRC8_N 0.52 33.0 3.48e-01 83.7% 69.2%
3909752 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.51 29.0 3.46e-01 80.0% 83.3%