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IMGVR_UViG_3300033463_000002-3300033463-Ga0310690_10000036416
Arc-VirIMGVR_UViG_3300033463_000002-3300033463-Ga0310690_10000036416
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 18-69
Domain cluster:
representative
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4zdoB00 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.67 | 42.0 | 2.43e-01 | 78.8% | 7.2% |
| 3l44A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.65 | 51.0 | 3.48e-01 | 96.2% | 24.0% |
| 8a6tB01 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.64 | 47.0 | 3.46e-01 | 78.8% | 41.4% |
| 1m2gA02 | 3.30.1600.10 | Alpha Beta › 2-Layer Sandwich › SIR2/SIRT2 'Small Domain' › SIR2/SIRT2 'Small Domain' | 0.63 | 44.0 | 3.68e-01 | 75.0% | 60.2% |
| 6jzaA00 | 3.30.60.30 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › | 0.62 | 36.0 | 3.13e-01 | 84.6% | 33.3% |
| 3mk7C01 | 6.10.280.130 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 41.0 | 3.45e-01 | 71.2% | 74.5% |
| 5n1qB02 | 3.30.70.470 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 42.0 | 3.00e-01 | 80.8% | 25.2% |
| 2p3nA01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.58 | 45.0 | 3.44e-01 | 88.5% | 100.0% |
| 2dulA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.57 | 48.0 | 3.02e-01 | 100.0% | 33.4% |
| 2kt2A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 36.0 | 3.36e-01 | 76.9% | 47.8% |
| 1cfyA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.57 | 47.0 | 3.64e-01 | 98.1% | 89.5% |
| 5wb7E00 | 2.10.25.10 | Mainly Beta › Ribbon › Laminin › Laminin | 0.57 | 32.0 | 3.37e-01 | 82.7% | 59.6% |
| 1z1nX02 | 3.90.10.10 | Alpha Beta › Alpha-Beta Complex › Cytochrome C3 › Cytochrome C3 | 0.56 | 38.0 | 3.01e-01 | 96.2% | 31.6% |
| 3bwnD01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.56 | 41.0 | 3.00e-01 | 78.8% | 31.9% |
| 5axmB00 | 3.30.70.3000 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) | 0.56 | 46.0 | 3.10e-01 | 98.1% | 81.6% |
| 2qejD01 | 3.10.20.120 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.56 | 39.0 | 2.99e-01 | 73.1% | 45.8% |
| 2o8bA04 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.56 | 44.0 | 3.80e-01 | 88.5% | 71.1% |
| 2z8lA01 | 3.10.20.120 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.55 | 38.0 | 2.97e-01 | 73.1% | 46.2% |
| 4pfyA02 | 3.90.76.10 | Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 | 0.55 | 40.0 | 2.99e-01 | 80.8% | 37.4% |
| 1w36B03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 37.0 | 2.38e-01 | 73.1% | 69.6% |
| 2hoxA03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 39.0 | 3.07e-01 | 78.8% | 38.9% |
| 3akjA02 | 1.10.1070.20 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › | 0.53 | 38.0 | 2.65e-01 | 80.8% | 23.9% |
| 3iwaA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.53 | 39.0 | 2.82e-01 | 80.8% | 89.2% |
| 6inxA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.52 | 31.0 | 2.90e-01 | 76.9% | 46.2% |
| 3en8A01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 40.0 | 3.20e-01 | 86.5% | 92.0% |
| 3znuA00 | 3.30.70.1060 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel | 0.52 | 42.0 | 3.47e-01 | 88.5% | 64.9% |
| 3peiA01 | 3.40.220.10 | Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 | 0.51 | 38.0 | 2.85e-01 | 82.7% | 35.0% |
| 2d8bA01 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.51 | 42.0 | 3.18e-01 | 94.2% | 85.0% |
| 1l1lA01 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.51 | 43.0 | 2.51e-01 | 100.0% | 63.6% |
| 3p9aF00 | 1.10.132.80 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.50 | 38.0 | 2.82e-01 | 80.8% | 59.7% |
| 3aa0B01 | 1.20.58.570 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › F-actin capping protein, alpha/beta subunit, N-terminal domain | 0.50 | 41.0 | 3.59e-01 | 98.1% | 81.8% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1207585 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.73 | 52.0 | 4.53e-01 | 76.9% | 56.8% |
| 3060306 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.71 | 51.0 | 4.01e-01 | 76.9% | 39.8% |
| 1548765 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.69 | 51.0 | 4.06e-01 | 78.8% | 43.1% |
| 1247620 | 101.1.1.72 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › GP3_package | 0.66 | 39.0 | 2.87e-01 | 84.6% | 22.3% |
| 3262355 | 263.1.1.1 ↗ | a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF | 0.66 | 49.0 | 3.97e-01 | 80.8% | 44.1% |
| 3502013 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.65 | 41.0 | 3.96e-01 | 84.6% | 55.0% |
| 5017559 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.64 | 47.0 | 4.39e-01 | 82.7% | 63.1% |
| 4985406 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.62 | 46.0 | 4.07e-01 | 80.8% | 57.0% |
| 2028124 | 223.3.1.8 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase2 | 0.62 | 45.0 | 4.81e-01 | 82.7% | 93.2% |
| 5061624 | 304.3.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA | 0.62 | 38.0 | 3.64e-01 | 76.9% | 53.3% |
| 1504506 | 223.3.1.8 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase2 | 0.60 | 43.0 | 4.60e-01 | 80.8% | 87.0% |
| 3518004 | 2003.1.9.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF | 0.60 | 43.0 | 2.57e-01 | 84.6% | 9.1% |
| 3506749 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.60 | 47.0 | 3.24e-01 | 84.6% | 66.7% |
| 3838596 | 2008.1.1.85 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_TdeIII | 0.59 | 45.0 | 3.00e-01 | 82.7% | 24.4% |
| 3515089 | 304.3.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA | 0.59 | 40.0 | 3.77e-01 | 80.8% | 55.9% |
| None | — | 0.59 | 44.0 | 2.92e-01 | 86.5% | 84.5% | |
| 6892 | 223.3.1.8 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase2 | 0.57 | 39.0 | 4.28e-01 | 75.0% | 94.9% |
| 1505442 | 223.3.1.8 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase2 | 0.56 | 41.0 | 4.07e-01 | 84.6% | 73.2% |
| 1921561 | 1110.1.1.0 ↗ | beta sandwiches › Flagellar hook subunit protein FlgE beta sandwich domain › Flagellar hook subunit protein FlgE beta sandwich domain › Flagellar hook subunit protein FlgE beta sandwich domain | 0.56 | 38.0 | 2.83e-01 | 82.7% | 23.9% |
| 3688523 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.56 | 43.0 | 3.55e-01 | 84.6% | 65.3% |
| 4557450 | 7573.1.1.1 ↗ | a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran | 0.55 | 39.0 | 2.88e-01 | 76.9% | 28.9% |
| 3602244 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.55 | 42.0 | 3.18e-01 | 88.5% | 88.2% |
| 3530709 | 6166.1.1.1 ↗ | alpha bundles › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › ERG4_ERG24 | 0.55 | 41.0 | 2.78e-01 | 82.7% | 51.5% |
| 3666034 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.54 | 39.0 | 3.22e-01 | 80.8% | 39.1% |
| 5076912 | 304.4.1.3 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › YCII | 0.54 | 42.0 | 3.75e-01 | 84.6% | 84.0% |
| 2440217 | 223.3.1.8 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase2 | 0.54 | 38.0 | 4.07e-01 | 86.5% | 100.0% |
| 3204763 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.54 | 45.0 | 2.95e-01 | 100.0% | 87.5% |
| 4087732 | 2500.1.1.0 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel | 0.54 | 47.0 | 2.74e-01 | 100.0% | 77.2% |
| 3962604 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.54 | 48.0 | 3.02e-01 | 100.0% | 47.4% |
| 3088296 | 4272.1.1.1 ↗ | a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa | 0.53 | 40.0 | 2.86e-01 | 90.4% | 61.1% |
| 3325733 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.53 | 31.0 | 3.21e-01 | 71.2% | 48.0% |
| 3204533 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.52 | 32.0 | 2.94e-01 | 75.0% | 40.0% |
| 4983462 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.52 | 41.0 | 3.83e-01 | 86.5% | 80.0% |
| 5062966 | 327.11.1.16 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › KH_1 | 0.51 | 34.0 | 3.34e-01 | 80.8% | 60.0% |
| 4011234 | 4291.1.1.0 ↗ | beta barrels › Oxysterol-binding protein › Oxysterol-binding protein › Oxysterol-binding protein | 0.51 | 39.0 | 2.38e-01 | 86.5% | 39.0% |
| 3766059 | 389.1.1.0 ↗ | few secondary structure elements › EGF-like › EGF-related › EGF/Laminin | 0.50 | 31.0 | 3.30e-01 | 82.7% | 74.4% |
| 3061774 | 223.3.1.8 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase2 | 0.50 | 36.0 | 3.79e-01 | 80.8% | 90.9% |
| 4265934 | 2007.1.16.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn | 0.50 | 40.0 | 2.91e-01 | 90.4% | 75.0% |