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IMGVR_UViG_3300033490_000046-3300033490-Ga0326760_10041794
Arc-VirIMGVR_UViG_3300033490_000046-3300033490-Ga0326760_10041794
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 5-143
Domain cluster:
representative
D2
medium
residues 144-197
Domain cluster:
representative
CATH (49)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.76 | 58.0 | 5.13e-01 | 83.3% | 100.0% |
| 1gcbA01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.75 | 63.0 | 3.74e-01 | 94.4% | 32.5% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.75 | 55.0 | 3.80e-01 | 79.6% | 91.3% |
| 1xdxA01 | 3.30.1140.40 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 | 0.73 | 55.0 | 4.61e-01 | 85.2% | 46.0% |
| 2e62A01 | 6.10.140.420 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 60.0 | 6.07e-01 | 94.4% | 96.2% |
| 2g8lB01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.72 | 52.0 | 4.96e-01 | 92.6% | 64.2% |
| 1e6cA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.72 | 52.0 | 3.66e-01 | 77.8% | 27.6% |
| 3kr9A02 | 1.10.287.1890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 48.0 | 4.68e-01 | 79.6% | 62.3% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.72 | 53.0 | 4.56e-01 | 77.8% | 61.7% |
| 3sjqC00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 52.0 | 4.54e-01 | 77.8% | 62.5% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.70 | 56.0 | 3.77e-01 | 90.7% | 46.9% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.70 | 54.0 | 5.15e-01 | 83.3% | 81.0% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.69 | 56.0 | 5.29e-01 | 90.7% | 96.9% |
| 1s5jA04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.69 | 50.0 | 4.85e-01 | 77.8% | 83.6% |
| 5b1oA00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.68 | 48.0 | 4.55e-01 | 75.9% | 61.5% |
| 2oznB01 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.68 | 55.0 | 4.82e-01 | 88.9% | 80.0% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.68 | 55.0 | 4.49e-01 | 90.7% | 98.1% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.67 | 55.0 | 4.08e-01 | 88.9% | 80.5% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 51.0 | 4.00e-01 | 83.3% | 61.0% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.67 | 55.0 | 4.83e-01 | 94.4% | 63.5% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.67 | 54.0 | 4.48e-01 | 92.6% | 54.5% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.66 | 51.0 | 4.53e-01 | 83.3% | 83.1% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 49.0 | 4.12e-01 | 79.6% | 51.1% |
| 2i7uA00 | 6.10.250.1010 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.66 | 51.0 | 4.96e-01 | 87.0% | 79.0% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.66 | 51.0 | 3.04e-01 | 85.2% | 13.1% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 50.0 | 4.21e-01 | 83.3% | 68.5% |
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.65 | 54.0 | 3.97e-01 | 96.3% | 73.9% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 50.0 | 4.45e-01 | 83.3% | 60.3% |
| 1z0pA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 50.0 | 4.57e-01 | 85.2% | 84.9% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 51.0 | 4.13e-01 | 87.0% | 50.5% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.64 | 49.0 | 4.80e-01 | 83.3% | 79.7% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.64 | 50.0 | 3.80e-01 | 83.3% | 57.1% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.64 | 44.0 | 4.22e-01 | 72.2% | 93.8% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 48.0 | 3.80e-01 | 81.5% | 39.3% |
| 2yevA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 49.0 | 4.40e-01 | 83.3% | 68.9% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 50.0 | 4.05e-01 | 85.2% | 55.9% |
| 3m6jA01 | 1.20.1260.40 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.63 | 46.0 | 3.62e-01 | 77.8% | 37.6% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.62 | 49.0 | 4.60e-01 | 88.9% | 73.5% |
| 2c5iT00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 48.0 | 4.04e-01 | 87.0% | 68.1% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.61 | 48.0 | 3.94e-01 | 87.0% | 61.8% |
| 2ckoA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.60 | 53.0 | 3.35e-01 | 98.1% | 19.8% |
| 3h6pC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.60 | 49.0 | 4.93e-01 | 90.7% | 89.3% |
| 4q20A01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.59 | 52.0 | 4.52e-01 | 98.1% | 76.8% |
| 1vibA00 | 1.10.287.120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like | 0.59 | 45.0 | 4.57e-01 | 88.9% | 87.3% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.59 | 46.0 | 3.35e-01 | 87.0% | 57.9% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 44.0 | 4.54e-01 | 87.0% | 98.0% |
| 1wpbG01 | 1.10.287.680 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.55 | 38.0 | 3.87e-01 | 92.6% | 74.1% |
| 2qkdA04 | 2.60.120.1040 | Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain | 0.52 | 42.0 | 3.27e-01 | 92.6% | 61.4% |
| 2b3tB01 | 6.10.140.1980 | Special › Helix non-globular › Helix Hairpins › | 0.51 | 39.0 | 3.77e-01 | 87.0% | 86.2% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5022363 | 632.11.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DUF357 | 0.76 | 55.0 | 4.68e-01 | 77.8% | 48.2% |
| 4445312 | 3812.1.1.0 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE | 0.75 | 57.0 | 5.88e-01 | 83.3% | 88.0% |
| 3456370 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.74 | 53.0 | 3.76e-01 | 75.9% | 27.1% |
| 3513381 | 4082.1.1.0 ↗ | alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain | 0.73 | 59.0 | 5.72e-01 | 90.7% | 88.3% |
| 3808476 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.73 | 54.0 | 4.91e-01 | 77.8% | 62.9% |
| 3655782 | 101.1.2.598 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, POLR3C_WHD | 0.72 | 58.0 | 3.55e-01 | 87.0% | 91.6% |
| 1505665 | 192.27.1.1 ↗ | alpha bundles › Long alpha-hairpin › Helical hairpin in putative tRNA methyltransferase › Helical hairpin in putative tRNA methyltransferase › TrmK | 0.72 | 48.0 | 4.65e-01 | 79.6% | 61.3% |
| 3503635 | 605.1.1.133 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › OST3_OST6 | 0.71 | 51.0 | 3.94e-01 | 75.9% | 36.7% |
| 3743175 | 630.1.1.0 ↗ | a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain | 0.71 | 52.0 | 3.58e-01 | 77.8% | 27.0% |
| 3967290 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.71 | 52.0 | 4.76e-01 | 77.8% | 61.4% |
| 4337700 | 605.1.1.108 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › GrpE | 0.71 | 55.0 | 4.52e-01 | 83.3% | 49.5% |
| 4537890 | 192.17.1.19 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › GrpE | 0.71 | 58.0 | 5.69e-01 | 94.4% | 91.7% |
| 3262164 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.70 | 51.0 | 3.25e-01 | 77.8% | 17.7% |
| 3810882 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 51.0 | 3.21e-01 | 77.8% | 15.6% |
| 3503725 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.69 | 56.0 | 3.90e-01 | 94.4% | 74.0% |
| 3618651 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.69 | 54.0 | 4.60e-01 | 83.3% | 58.8% |
| 4106620 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.69 | 54.0 | 4.80e-01 | 83.3% | 66.7% |
| 3286591 | 101.1.2.612 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR_2, PF27059 | 0.69 | 47.0 | 3.41e-01 | 79.6% | 25.5% |
| 3408508 | 3712.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 | 0.69 | 51.0 | 4.44e-01 | 77.8% | 61.3% |
| 3757869 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.69 | 60.0 | 4.97e-01 | 98.1% | 91.6% |
| 3468223 | 101.1.2.90 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_9 | 0.69 | 58.0 | 3.51e-01 | 92.6% | 83.5% |
| 3975961 | 5058.1.1.88 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_TM1 | 0.69 | 57.0 | 4.68e-01 | 92.6% | 75.0% |
| 5039854 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.69 | 53.0 | 4.72e-01 | 83.3% | 86.7% |
| 3634546 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.68 | 50.0 | 4.51e-01 | 79.6% | 58.7% |
| 3386554 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.67 | 53.0 | 4.70e-01 | 83.3% | 86.7% |
| 3890229 | 603.1.1.64 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › CUPID | 0.67 | 52.0 | 4.29e-01 | 83.3% | 49.5% |
| 3350514 | 3922.1.1.145 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › KIF21A_4th | 0.67 | 52.0 | 3.67e-01 | 83.3% | 42.5% |
| 3278800 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.66 | 51.0 | 4.59e-01 | 83.3% | 66.7% |
| 4978412 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.66 | 50.0 | 3.53e-01 | 83.3% | 28.6% |
| 3503210 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.65 | 49.0 | 4.42e-01 | 81.5% | 62.7% |
| 3441901 | 632.1.1.13 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N | 0.65 | 51.0 | 4.44e-01 | 83.3% | 100.0% |
| 3971706 | 5071.3.1.1 ↗ | alpha bundles › cytochrome bc1 complex 11 kDa protein-like › DUF465 › DUF465 › DUF465 | 0.65 | 55.0 | 5.07e-01 | 94.4% | 95.7% |
| 4000626 | 5043.1.1.11 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › ATP_synt_H | 0.64 | 51.0 | 4.55e-01 | 90.7% | 62.5% |
| 3681259 | 5058.1.1.57 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › V-SNARE | 0.64 | 50.0 | 4.32e-01 | 85.2% | 55.3% |
| 3484908 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 50.0 | 3.96e-01 | 83.3% | 63.8% |
| None | — | 0.64 | 50.0 | 3.03e-01 | 85.2% | 27.3% | |
| 3700999 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.63 | 47.0 | 4.02e-01 | 81.5% | 66.7% |
| 3283001 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.62 | 49.0 | 4.11e-01 | 87.0% | 75.8% |
| 3900923 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 48.0 | 4.00e-01 | 88.9% | 51.0% |
| 3793286 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.61 | 50.0 | 3.49e-01 | 96.3% | 79.0% |
| 5030079 | 2002.1.1.60 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › AP_endonuc_2 | 0.59 | 50.0 | 2.92e-01 | 98.1% | 57.8% |
| 4617701 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.57 | 48.0 | 4.24e-01 | 94.4% | 70.0% |
| 3961630 | 101.1.2.456 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_MmpR5 | 0.55 | 45.0 | 3.26e-01 | 92.6% | 44.4% |
| 3184698 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.55 | 43.0 | 3.72e-01 | 90.7% | 100.0% |
| 3286725 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.50 | 42.0 | 2.90e-01 | 94.4% | 28.1% |