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IMGVR_UViG_3300033781_000023-3300033781-Ga0326759_00045_26579_27496
Arc-VirIMGVR_UViG_3300033781_000023-3300033781-Ga0326759_00045_26579_27496
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 9-220
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01757.29 best | Acyl_transf_3 | 65.8 | 5.10e-18 | 100.0% | 65.0% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.58 | 45.0 | 4.74e-01 | 96.7% | 89.8% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.57 | 37.0 | 4.26e-01 | 97.2% | 86.7% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.57 | 42.0 | 4.35e-01 | 94.3% | 82.0% |
| 1sj7C00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.54 | 38.0 | 4.26e-01 | 98.1% | 89.8% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 44.0 | 4.38e-01 | 94.8% | 82.6% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 38.0 | 3.96e-01 | 95.3% | 77.6% |
| 7zh0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 47.0 | 3.78e-01 | 96.2% | 89.7% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 27.0 | 3.21e-01 | 99.5% | 71.6% |
ECOD (47)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3988301 | 5050.1.1.60 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 | 0.65 | 41.0 | 4.24e-01 | 95.8% | 64.9% |
| 4500157 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.60 | 42.0 | 4.03e-01 | 96.7% | 62.1% |
| 3587785 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 42.0 | 4.45e-01 | 96.7% | 79.5% |
| 3832320 | 5050.1.1.26 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UVB_sens_prot | 0.60 | 41.0 | 3.58e-01 | 70.8% | 45.5% |
| 3400243 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 41.0 | 4.17e-01 | 96.7% | 70.0% |
| 3948680 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 43.0 | 4.42e-01 | 96.7% | 78.0% |
| 3989758 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 43.0 | 4.60e-01 | 94.8% | 86.5% |
| 3193593 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.58 | 43.0 | 4.14e-01 | 96.7% | 67.2% |
| 3916886 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 43.0 | 4.36e-01 | 96.7% | 76.7% |
| 3934402 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.58 | 42.0 | 4.38e-01 | 96.7% | 80.5% |
| 3202668 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 44.0 | 4.44e-01 | 96.7% | 78.1% |
| 4971427 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 43.0 | 4.62e-01 | 94.8% | 89.1% |
| 4565029 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 41.0 | 4.25e-01 | 94.8% | 76.5% |
| 4071397 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 41.0 | 4.19e-01 | 96.7% | 77.0% |
| 3245292 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.57 | 40.0 | 3.88e-01 | 96.2% | 64.3% |
| 4018363 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 44.0 | 4.61e-01 | 96.7% | 87.7% |
| 3948903 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 41.0 | 4.21e-01 | 95.3% | 78.5% |
| 3697052 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 42.0 | 4.24e-01 | 96.7% | 76.3% |
| 5009908 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 39.0 | 4.08e-01 | 93.9% | 76.9% |
| 3961165 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 47.0 | 4.64e-01 | 98.6% | 82.2% |
| 3949320 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.56 | 40.0 | 4.17e-01 | 96.7% | 78.0% |
| 3714325 | 5050.1.1.59 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP, MFS_1 | 0.55 | 44.0 | 4.34e-01 | 95.3% | 78.2% |
| 3336589 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.55 | 43.0 | 4.27e-01 | 93.4% | 76.8% |
| 5055035 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 41.0 | 4.20e-01 | 92.9% | 79.5% |
| 3976872 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 41.0 | 4.25e-01 | 96.7% | 80.0% |
| 3511776 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 42.0 | 4.27e-01 | 98.1% | 80.0% |
| 3506104 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 41.0 | 4.05e-01 | 94.8% | 72.3% |
| 3838934 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 41.0 | 4.26e-01 | 96.7% | 82.6% |
| 4587243 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 39.0 | 4.11e-01 | 95.3% | 79.5% |
| 4001246 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 40.0 | 4.05e-01 | 95.3% | 75.7% |
| 4360283 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 42.0 | 4.13e-01 | 95.3% | 74.3% |
| 3774052 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 39.0 | 4.05e-01 | 96.7% | 77.0% |
| 3183504 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 44.0 | 4.28e-01 | 94.8% | 77.7% |
| 3188177 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 42.0 | 4.17e-01 | 93.4% | 76.4% |
| 4929352 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 39.0 | 3.97e-01 | 96.7% | 76.1% |
| 3744639 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 43.0 | 4.20e-01 | 94.8% | 76.9% |
| 4416029 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 39.0 | 4.02e-01 | 95.3% | 78.5% |
| 3527410 | 5050.1.1.6 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP | 0.53 | 44.0 | 4.14e-01 | 96.7% | 72.5% |
| 3849233 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.53 | 45.0 | 4.55e-01 | 100.0% | 89.7% |
| 4646391 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 40.0 | 4.09e-01 | 96.2% | 79.5% |
| 4023646 | 174.1.1.88 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7641 | 0.53 | 30.0 | 3.81e-01 | 70.8% | 93.6% |
| 5052818 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 39.0 | 4.08e-01 | 96.7% | 84.2% |
| 4485584 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 39.0 | 4.06e-01 | 98.6% | 82.0% |
| 3610924 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 31.0 | 3.55e-01 | 96.7% | 78.1% |
| 3279228 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 39.0 | 3.92e-01 | 96.7% | 78.1% |
| 3403967 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.51 | 40.0 | 4.31e-01 | 91.0% | 95.1% |
| 3516367 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.51 | 28.0 | 3.36e-01 | 95.8% | 79.3% |
D2
high
residues 228-302
Domain cluster:
rep: IMGVR_UViG_3300007812_000019-3300007812-Ga0105109_100035011__D129-188
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3fghA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.72 | 56.0 | 5.89e-01 | 93.3% | 92.5% |
| 2genA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.68 | 48.0 | 3.61e-01 | 78.7% | 29.8% |
| 4i9oA00 | 1.10.246.20 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain | 0.63 | 37.0 | 3.72e-01 | 89.3% | 55.1% |
| 2cs1A00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.59 | 47.0 | 4.42e-01 | 90.7% | 71.7% |
| 3teqB00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 44.0 | 4.01e-01 | 100.0% | 62.4% |
| 3ckdA02 | 1.20.58.360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines | 0.54 | 43.0 | 3.69e-01 | 88.0% | 54.8% |
| 3vaaA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 40.0 | 3.12e-01 | 82.7% | 92.6% |
| 1n4kA02 | 1.25.10.30 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain | 0.53 | 41.0 | 3.35e-01 | 85.3% | 70.3% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3728650 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.81 | 43.0 | 4.48e-01 | 94.7% | 57.1% |
| 5022754 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.79 | 51.0 | 3.77e-01 | 100.0% | 27.8% |
| 4504853 | 547.1.1.0 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain | 0.67 | 42.0 | 3.85e-01 | 93.3% | 48.0% |
| 4085263 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.66 | 42.0 | 3.81e-01 | 93.3% | 48.0% |
| 4967576 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.64 | 47.0 | 3.80e-01 | 78.7% | 80.7% |
| 4085257 | 547.1.1.4 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Shikimate_DH | 0.64 | 50.0 | 3.59e-01 | 88.0% | 95.7% |
| 3940302 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.62 | 49.0 | 3.91e-01 | 96.0% | 42.7% |
| 3471666 | 190.1.1.1 ↗ | alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box | 0.61 | 48.0 | 4.88e-01 | 88.0% | 85.3% |
| 3839827 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.60 | 51.0 | 3.73e-01 | 100.0% | 67.8% |
| 3589064 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.57 | 46.0 | 3.33e-01 | 88.0% | 56.3% |
| 4179286 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.56 | 41.0 | 3.96e-01 | 93.3% | 69.4% |
| 3222769 | 60.1.2.1 ↗ | beta barrels › SPOC domain-like › SPOC domain-related › Ku70/80 subunit middle domain › Ku | 0.52 | 38.0 | 2.48e-01 | 77.3% | 19.1% |