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IMGVR_UViG_3300035102_000274-3300035102-Ga0376526_005380_2_376
Arc-VirIMGVR_UViG_3300035102_000274-3300035102-Ga0376526_005380_2_376
Identity
- Kingdom:
- archaea
Quality
89.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-58
Domain cluster:
representative
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4jiuA00 | 3.30.2010.10 | Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" | 0.78 | 60.0 | 4.94e-01 | 87.9% | 46.7% |
| 4jixB00 | 3.30.2010.10 | Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" | 0.76 | 60.0 | 5.01e-01 | 94.8% | 49.0% |
| 2epkX01 | 3.30.160.230 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › N-acetyl-beta-d-glucosaminidase | 0.63 | 51.0 | 4.58e-01 | 87.9% | 63.7% |
| 1gcaA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.62 | 53.0 | 3.95e-01 | 98.3% | 90.7% |
| 4rckA00 | 3.40.50.410 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain | 0.60 | 41.0 | 2.84e-01 | 70.7% | 41.7% |
| 4rkrD02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 43.0 | 3.27e-01 | 81.0% | 100.0% |
| 4r16A02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.58 | 47.0 | 3.41e-01 | 94.8% | 85.2% |
| 3upsA00 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.58 | 49.0 | 3.96e-01 | 93.1% | 74.1% |
| 7n0eB02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.58 | 47.0 | 3.70e-01 | 89.7% | 67.2% |
| 1iokA02 | 3.30.260.10 | Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain | 0.58 | 46.0 | 3.96e-01 | 87.9% | 62.0% |
| 1vb3A03 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 45.0 | 3.38e-01 | 86.2% | 76.0% |
| 1o22A00 | 3.90.1000.10 | Alpha Beta › Alpha-Beta Complex › Orphan Protein Tm0875; Chain: A; › Hypothetical protein TM0875 | 0.57 | 45.0 | 3.36e-01 | 84.5% | 78.5% |
| 4g41A00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.57 | 39.0 | 2.66e-01 | 74.1% | 33.5% |
| 2v3uA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.57 | 48.0 | 3.63e-01 | 98.3% | 63.9% |
| 5d8nA01 | 3.40.220.10 | Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 | 0.56 | 44.0 | 3.07e-01 | 84.5% | 40.4% |
| 6whcA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 39.0 | 2.67e-01 | 75.9% | 19.2% |
| 1e8cA01 | 3.40.1390.10 | Alpha Beta › 3-Layer(aba) Sandwich › Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 › MurE/MurF, N-terminal domain | 0.55 | 39.0 | 3.32e-01 | 75.9% | 81.2% |
| 3h5tA03 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 46.0 | 3.42e-01 | 94.8% | 76.4% |
| 6j7xA01 | 1.25.40.120 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Protein prenylyltransferase | 0.54 | 41.0 | 2.60e-01 | 81.0% | 25.5% |
| 4rt5A00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.54 | 43.0 | 3.68e-01 | 93.1% | 96.0% |
| 4q0cA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 44.0 | 3.35e-01 | 96.6% | 50.3% |
| 2o0aA00 | 3.40.850.20 | Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › | 0.52 | 40.0 | 2.59e-01 | 84.5% | 65.8% |
| 3d36B01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.52 | 42.0 | 3.13e-01 | 91.4% | 61.9% |
| 2qy6A01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.51 | 45.0 | 3.04e-01 | 100.0% | 60.9% |
| 4q20A02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.51 | 39.0 | 3.12e-01 | 93.1% | 92.6% |
| 1h65B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 43.0 | 2.77e-01 | 93.1% | 22.3% |
ECOD (75)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5075577 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.85 | 77.0 | 5.59e-01 | 98.3% | 39.3% |
| 5084062 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.84 | 72.0 | 5.87e-01 | 94.8% | 57.1% |
| 3386105 | 2498.1.1.17 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YgjP-like | 0.82 | 69.0 | 5.30e-01 | 98.3% | 41.5% |
| 5030912 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.82 | 71.0 | 4.51e-01 | 96.6% | 20.4% |
| 4989311 | 2498.1.1.17 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YgjP-like | 0.79 | 71.0 | 5.13e-01 | 100.0% | 69.0% |
| 5050240 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.78 | 69.0 | 4.56e-01 | 100.0% | 31.1% |
| 4027214 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.77 | 66.0 | 5.84e-01 | 98.3% | 71.8% |
| 4024134 | 2498.1.1.65 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › MATCAP | 0.76 | 65.0 | 3.93e-01 | 94.8% | 15.3% |
| 4945343 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.76 | 63.0 | 4.18e-01 | 93.1% | 23.5% |
| 5031475 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.75 | 67.0 | 4.24e-01 | 100.0% | 93.9% |
| 4969796 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.74 | 58.0 | 4.90e-01 | 87.9% | 86.0% |
| 2514242 | 2498.1.1.39 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like | 0.73 | 62.0 | 4.86e-01 | 96.6% | 44.5% |
| 5036683 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.73 | 56.0 | 4.40e-01 | 86.2% | 39.2% |
| 5055672 | 2498.1.1.39 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like | 0.73 | 63.0 | 5.24e-01 | 100.0% | 56.2% |
| 3644314 | 2498.1.1.39 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like | 0.73 | 61.0 | 4.68e-01 | 94.8% | 45.9% |
| 3290645 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.73 | 56.0 | 4.44e-01 | 86.2% | 40.8% |
| 3686613 | 261.1.1.0 ↗ | a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain | 0.72 | 63.0 | 4.66e-01 | 98.3% | 50.7% |
| 4937460 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.72 | 61.0 | 5.04e-01 | 96.6% | 58.1% |
| 4977205 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.71 | 58.0 | 3.90e-01 | 93.1% | 22.9% |
| 4929032 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.71 | 58.0 | 4.33e-01 | 94.8% | 34.8% |
| 4966006 | 2498.1.1.163 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › DUF5781 | 0.70 | 59.0 | 3.92e-01 | 98.3% | 23.3% |
| 5061805 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.70 | 59.0 | 4.91e-01 | 100.0% | 86.4% |
| 5010190 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.70 | 56.0 | 3.94e-01 | 98.3% | 26.3% |
| 3678059 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.69 | 47.0 | 3.03e-01 | 70.7% | 16.8% |
| 3754954 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.69 | 57.0 | 3.83e-01 | 93.1% | 23.5% |
| 3252321 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.69 | 59.0 | 4.39e-01 | 98.3% | 49.0% |
| 5083216 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.69 | 49.0 | 3.48e-01 | 89.7% | 24.4% |
| 3838257 | 2498.4.1.1 ↗ | mixed a+b and a/b › Zincin-like › HSP90 C-terminal domain (C-terminal part of Pfam 00183) › HSP90 C-terminal domain (C-terminal part of Pfam 00183) › HSP90 | 0.68 | 60.0 | 4.65e-01 | 100.0% | 55.4% |
| 3286933 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.68 | 55.0 | 4.18e-01 | 87.9% | 38.8% |
| 5080625 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.67 | 57.0 | 4.64e-01 | 98.3% | 83.5% |
| 4416753 | 2498.1.1.59 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_U49 | 0.67 | 57.0 | 3.75e-01 | 100.0% | 39.0% |
| 4396540 | 220.1.1.12 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Myosin_TH1 | 0.67 | 52.0 | 3.67e-01 | 86.2% | 100.0% |
| 3990083 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.66 | 44.0 | 4.28e-01 | 75.9% | 61.5% |
| 3868678 | 2498.1.1.65 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › MATCAP | 0.66 | 53.0 | 3.34e-01 | 93.1% | 16.4% |
| 4940509 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.66 | 52.0 | 4.35e-01 | 91.4% | 50.0% |
| 4537352 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.66 | 47.0 | 3.42e-01 | 81.0% | 27.5% |
| 5058128 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.66 | 56.0 | 4.00e-01 | 100.0% | 37.4% |
| 5014658 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.66 | 56.0 | 3.71e-01 | 100.0% | 25.4% |
| 3176188 | 109.4.1.3157 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29173, PF29174, PF29177 | 0.65 | 52.0 | 3.17e-01 | 87.9% | 14.1% |
| 3601536 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.65 | 41.0 | 2.97e-01 | 91.4% | 22.4% |
| 3256855 | 2004.1.1.150 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DRMBL | 0.65 | 53.0 | 3.94e-01 | 91.4% | 90.7% |
| 4014518 | 261.1.1.0 ↗ | a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain | 0.64 | 52.0 | 3.98e-01 | 94.8% | 50.7% |
| 3290701 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.64 | 52.0 | 4.01e-01 | 93.1% | 44.1% |
| 1837251 | 2498.2.1.5 ↗ | mixed a+b and a/b › Zincin-like › beta-N-acetylhexosaminidase-like domain › beta-N-acetylhexosaminidase-like domain › GcnA_N | 0.63 | 51.0 | 4.54e-01 | 87.9% | 62.2% |
| 5013452 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.63 | 52.0 | 3.60e-01 | 100.0% | 27.6% |
| 5027859 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.63 | 52.0 | 4.09e-01 | 100.0% | 47.8% |
| 5080626 | 2498.1.1.39 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like | 0.61 | 51.0 | 4.23e-01 | 100.0% | 100.0% |
| 5024540 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.61 | 46.0 | 3.51e-01 | 96.6% | 33.1% |
| 4935744 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.60 | 50.0 | 4.25e-01 | 100.0% | 58.1% |
| 4968472 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.60 | 51.0 | 3.47e-01 | 100.0% | 25.3% |
| 3953551 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.59 | 47.0 | 3.28e-01 | 89.7% | 73.5% |
| 4223692 | 2498.1.1.58 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › DUF2201_N | 0.59 | 50.0 | 3.69e-01 | 100.0% | 35.9% |
| 3320588 | 2006.1.6.9 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Copine | 0.58 | 42.0 | 3.09e-01 | 77.6% | 81.3% |
| 3586986 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.57 | 46.0 | 3.54e-01 | 89.7% | 81.5% |
| 3390790 | 2498.5.1.0 ↗ | mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like | 0.57 | 46.0 | 3.99e-01 | 87.9% | 61.1% |
| 4990363 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.57 | 51.0 | 3.52e-01 | 100.0% | 49.5% |
| 4939507 | 316.1.1.54 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › RlaP | 0.56 | 47.0 | 3.96e-01 | 93.1% | 64.0% |
| 4809709 | 211.1.1.33 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › RsfS | 0.56 | 45.0 | 3.63e-01 | 89.7% | 65.2% |
| 4341093 | 2493.1.1.1 ↗ | a/b three-layered sandwiches › MurF and HprK N-domain-like › MurF and HprK N-domain-like › MurF and HprK N-domain-like › Mur_ligase | 0.54 | 41.0 | 3.46e-01 | 84.5% | 83.8% |
| 3962296 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.54 | 38.0 | 2.65e-01 | 79.3% | 19.6% |
| 3928418 | 3785.1.1.1 ↗ | a+b three layers › Suppressor of Fused, C-terminal domain › Suppressor of Fused, C-terminal domain › Suppressor of Fused, C-terminal domain › SARA_C | 0.54 | 45.0 | 3.51e-01 | 96.6% | 60.7% |
| 4224450 | 316.1.1.5 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › RsfS | 0.54 | 44.0 | 3.66e-01 | 91.4% | 70.0% |
| 3601785 | 2007.2.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II | 0.53 | 41.0 | 2.73e-01 | 89.7% | 52.5% |
| 3573534 | 2006.1.5.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase | 0.53 | 41.0 | 2.82e-01 | 91.4% | 64.5% |
| 3660261 | 2006.1.4.7 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN_YacP | 0.53 | 41.0 | 2.93e-01 | 84.5% | 44.0% |
| 4974758 | 2008.1.1.51 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › McrBC | 0.53 | 45.0 | 3.41e-01 | 100.0% | 77.4% |
| 4060927 | 102.1.1.28 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_6 | 0.53 | 37.0 | 2.79e-01 | 89.7% | 26.3% |
| 3494153 | 109.4.1.18 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA | 0.52 | 37.0 | 2.56e-01 | 74.1% | 20.5% |
| 5067350 | 7518.1.1.0 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like | 0.52 | 40.0 | 3.36e-01 | 84.5% | 90.5% |
| 3954373 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.52 | 38.0 | 2.55e-01 | 84.5% | 71.9% |
| 3613771 | 7529.1.1.8 ↗ | a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › Pdase_M17_N2 | 0.52 | 41.0 | 2.93e-01 | 94.8% | 26.4% |
| 3239938 | 207.1.1.79 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › F-box | 0.52 | 37.0 | 2.39e-01 | 79.3% | 16.8% |
| 4026734 | 2003.1.5.73 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 | 0.52 | 42.0 | 2.89e-01 | 98.3% | 76.5% |
| 5001378 | 7512.1.1.30 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 | 0.51 | 42.0 | 2.77e-01 | 89.7% | 31.3% |
| 3470915 | 109.4.1.18 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA | 0.50 | 37.0 | 2.33e-01 | 79.3% | 13.2% |
D2
medium
residues 59-112
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3t38A01 | 1.10.8.1060 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Corynebacterium glutamicum thioredoxin-dependent arsenate reductase, N-terminal domain | 0.70 | 55.0 | 5.05e-01 | 88.9% | 66.2% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.68 | 46.0 | 3.68e-01 | 90.7% | 35.5% |
| 4gzrC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.66 | 49.0 | 4.76e-01 | 81.5% | 82.0% |
| 2oq1A02 | 1.10.930.10 | Mainly Alpha › Orthogonal Bundle › Syk Kinase; Chain A, domain 2 › Syk Kinase; Chain A, domain 2 | 0.66 | 49.0 | 5.23e-01 | 94.4% | 97.8% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.65 | 44.0 | 4.63e-01 | 70.4% | 79.6% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.65 | 50.0 | 3.74e-01 | 83.3% | 53.4% |
| 1x0tA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.64 | 45.0 | 4.37e-01 | 77.8% | 65.6% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.64 | 53.0 | 4.46e-01 | 98.1% | 55.4% |
| 1zu4A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.63 | 46.0 | 4.04e-01 | 79.6% | 49.4% |
| 3f2eA00 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 49.0 | 4.36e-01 | 88.9% | 60.2% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.63 | 43.0 | 3.25e-01 | 70.4% | 36.7% |
| 6hwjA01 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.62 | 49.0 | 3.29e-01 | 92.6% | 59.2% |
| 1h6qA00 | 2.170.150.10 | Mainly Beta › Beta Complex › Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A › Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A | 0.62 | 52.0 | 3.73e-01 | 96.3% | 39.3% |
| 3fxdC00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.62 | 43.0 | 4.44e-01 | 79.6% | 76.0% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 43.0 | 3.55e-01 | 74.1% | 67.3% |
| 1bh9B00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.61 | 46.0 | 3.99e-01 | 90.7% | 51.7% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.60 | 48.0 | 4.23e-01 | 96.3% | 59.3% |
| 4m70B00 | 1.10.246.200 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain | 0.60 | 51.0 | 4.38e-01 | 98.1% | 58.2% |
| 1y71A00 | 2.30.30.430 | Mainly Beta › Roll › SH3 type barrels. › Kinase associated protein B domain | 0.60 | 37.0 | 3.02e-01 | 70.4% | 31.2% |
| 1r5aA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 45.0 | 3.37e-01 | 81.5% | 39.7% |
| 3kztA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.59 | 49.0 | 3.65e-01 | 90.7% | 87.1% |
| 3woyA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 41.0 | 2.66e-01 | 72.2% | 29.3% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.59 | 47.0 | 3.85e-01 | 88.9% | 57.4% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 40.0 | 3.93e-01 | 72.2% | 67.2% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.57 | 46.0 | 3.73e-01 | 88.9% | 53.3% |
| 3n5lA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 42.0 | 4.20e-01 | 81.5% | 75.4% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 49.0 | 3.60e-01 | 100.0% | 67.4% |
| 2ggfA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 39.0 | 3.01e-01 | 87.0% | 31.4% |
| 2icwG01 | 1.20.120.390 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hla class ii histocompatibility antigen, dr alpha chain. Chain D, domain 1 | 0.53 | 45.0 | 3.53e-01 | 98.1% | 48.4% |
| 2c42A03 | 3.40.920.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 0.53 | 45.0 | 3.04e-01 | 98.1% | 41.5% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.52 | 41.0 | 3.80e-01 | 92.6% | 66.2% |
| 4od8D00 | 6.10.140.1880 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 36.0 | 3.76e-01 | 77.8% | 78.4% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.51 | 39.0 | 3.44e-01 | 87.0% | 64.0% |
ECOD (33)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3682257 | 284.1.3.9 ↗ | a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › WLM | 0.92 | 70.0 | 5.71e-01 | 85.2% | 47.8% |
| None | — | 0.90 | 71.0 | 5.31e-01 | 83.3% | 38.3% | |
| 3720589 | 2498.1.1.36 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › WLM | 0.87 | 70.0 | 5.05e-01 | 85.2% | 34.8% |
| 4021655 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.81 | 73.0 | 5.05e-01 | 98.1% | 40.0% |
| 3736764 | 3711.1.1.0 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein | 0.74 | 67.0 | 4.58e-01 | 100.0% | 55.0% |
| 3036753 | 397.7.1.0 ↗ | few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 | 0.72 | 53.0 | 5.32e-01 | 87.0% | 78.6% |
| 3438464 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.70 | 55.0 | 5.72e-01 | 100.0% | 96.0% |
| 3798232 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.69 | 53.0 | 4.66e-01 | 88.9% | 54.5% |
| 3617495 | 3860.1.1.0 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm | 0.68 | 53.0 | 4.80e-01 | 88.9% | 62.0% |
| 3511084 | 3922.1.1.225 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF842 | 0.68 | 59.0 | 4.52e-01 | 98.1% | 42.4% |
| 3832740 | 3567.1.1.16 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › DUF4110 | 0.67 | 51.0 | 4.31e-01 | 83.3% | 71.1% |
| 3347379 | 3470.1.1.26 ↗ | extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › DUF543 | 0.66 | 49.0 | 4.71e-01 | 85.2% | 100.0% |
| 3270445 | 633.21.1.22 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › COPI_assoc | 0.65 | 49.0 | 3.88e-01 | 83.3% | 80.9% |
| 3570117 | 375.6.1.2 ↗ | few secondary structure elements › Rubredoxin-like › FlhC-like › FlhC-like › PF31275 | 0.64 | 48.0 | 4.67e-01 | 81.5% | 78.3% |
| 3616157 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.63 | 50.0 | 4.15e-01 | 85.2% | 50.5% |
| 5001687 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.62 | 47.0 | 4.60e-01 | 90.7% | 74.6% |
| 3740646 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.62 | 53.0 | 4.71e-01 | 98.1% | 66.3% |
| 3392896 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.61 | 49.0 | 4.34e-01 | 94.4% | 63.5% |
| 4466618 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.61 | 52.0 | 4.56e-01 | 100.0% | 65.9% |
| 3406162 | 4006.1.1.13 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › DUF842 | 0.60 | 52.0 | 4.05e-01 | 98.1% | 44.8% |
| 3267527 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.60 | 46.0 | 4.20e-01 | 85.2% | 62.7% |
| 3927738 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.59 | 43.0 | 3.68e-01 | 81.5% | 45.3% |
| 3602815 | 524.1.1.0 ↗ | alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p | 0.59 | 48.0 | 3.65e-01 | 100.0% | 91.6% |
| 3318741 | 5059.1.1.55 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TauE | 0.59 | 48.0 | 2.94e-01 | 90.7% | 15.2% |
| 3598977 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.57 | 46.0 | 4.04e-01 | 90.7% | 56.5% |
| 4034213 | 632.2.1.5 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF1542 | 0.57 | 45.0 | 4.08e-01 | 92.6% | 77.5% |
| 3611212 | 109.4.1.326 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RICTOR_M | 0.56 | 40.0 | 2.53e-01 | 77.8% | 18.0% |
| 3958889 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.55 | 43.0 | 3.09e-01 | 88.9% | 52.4% |
| 3635975 | 3681.1.1.0 ↗ | a+b complex topology › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit | 0.54 | 44.0 | 3.97e-01 | 100.0% | 74.1% |
| 4136151 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.54 | 45.0 | 3.65e-01 | 90.7% | 85.0% |
| 3971315 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.52 | 41.0 | 3.45e-01 | 92.6% | 97.1% |
| 3933048 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.52 | 43.0 | 3.47e-01 | 90.7% | 53.0% |
| 4054880 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.51 | 42.0 | 3.52e-01 | 98.1% | 96.2% |