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IMGVR_UViG_3300036888_000141-3300036888-Ga0334830_000360_2092_2808

Arc-Vir

IMGVR_UViG_3300036888_000141-3300036888-Ga0334830_000360_2092_2808

Quality

83.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-97
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13392.13 best HNH_3 32.4 7.60e-08 44.1% 58.7%
D2 high residues 109-153
PDB
CATH (59)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1gccA00 3.30.730.10 Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › AP2/ERF domain 0.93 87.0 7.61e-01 100.0% 74.6%
7wq5A01 3.30.730.10 Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › AP2/ERF domain 0.90 82.0 7.49e-01 100.0% 81.0%
2azeB00 6.10.250.540 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.86 39.0 2.90e-01 82.2% 20.8%
6r9rA01 3.40.50.10640 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SSO1389-like 0.76 42.0 2.67e-01 100.0% 11.7%
4e1oA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.73 56.0 4.39e-01 84.4% 95.9%
2l2mA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.73 62.0 5.46e-01 100.0% 68.6%
4wxaA00 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.73 56.0 4.65e-01 86.7% 85.7%
3nyiA02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.72 61.0 4.41e-01 100.0% 46.0%
1mgpA02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.72 60.0 4.53e-01 100.0% 44.6%
2l2nA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.71 63.0 5.39e-01 100.0% 67.6%
7dvrA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 45.0 3.11e-01 93.3% 21.3%
6le1A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.69 48.0 4.16e-01 73.3% 95.6%
2mlgA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 42.0 3.46e-01 97.8% 35.1%
2dt8A02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.68 58.0 4.27e-01 100.0% 48.5%
2anrA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.68 55.0 4.62e-01 88.9% 96.0%
2q88A01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.68 54.0 3.87e-01 93.3% 30.1%
3l60A01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.68 58.0 3.75e-01 100.0% 33.6%
3htxA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.68 53.0 4.62e-01 93.3% 75.0%
1pzxA03 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.68 58.0 4.30e-01 100.0% 43.4%
1k8kC00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.66 52.0 3.08e-01 88.9% 27.4%
2zihC00 1.10.3630.10 Mainly Alpha › Orthogonal Bundle › yeast vps74-n-term truncation variant fold › yeast vps74-n-term truncation variant domain like 0.66 45.0 2.74e-01 71.1% 11.5%
2memA00 3.90.1150.190 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › SLED domain 0.66 50.0 3.75e-01 86.7% 89.1%
2pm6D01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.64 48.0 2.96e-01 84.4% 22.9%
2dmyA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.63 53.0 4.29e-01 100.0% 49.5%
4ykiA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.61 48.0 3.42e-01 93.3% 27.2%
1b8pA02 3.90.110.10 Alpha Beta › Alpha-Beta Complex › L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2 › Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal 0.61 47.0 3.15e-01 84.4% 72.1%
2ec4A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.60 46.0 3.36e-01 100.0% 66.7%
2uvaG01 1.20.1050.120 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 52.0 3.71e-01 100.0% 46.3%
6fndA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 42.0 2.83e-01 75.6% 60.8%
3s6gA02 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.60 41.0 2.94e-01 77.8% 22.6%
2in3A01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.59 45.0 4.01e-01 97.8% 95.1%
1rypL00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.58 49.0 3.25e-01 100.0% 75.9%
3hr6A02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 47.0 3.36e-01 97.8% 94.3%
3trkA01 3.90.70.110 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Alphavirus nsP2 protease domain 0.58 47.0 3.38e-01 91.1% 82.5%
1cnzA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.58 48.0 2.87e-01 93.3% 84.0%
4i9fA03 3.30.300.290 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.58 42.0 3.55e-01 77.8% 46.8%
3n7cA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 52.0 3.89e-01 100.0% 42.6%
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 50.0 4.10e-01 100.0% 92.9%
3tqfA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 42.0 2.95e-01 93.3% 21.2%
2od0A00 3.30.1460.30 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › YgaC/TfoX-N like chaperone 0.57 50.0 3.80e-01 97.8% 95.1%
6g85A01 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.57 48.0 3.40e-01 97.8% 99.3%
3k8aB00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 46.0 3.67e-01 100.0% 77.7%
1txdA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 49.0 3.62e-01 100.0% 41.3%
3zx7A02 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.56 42.0 3.03e-01 84.4% 58.4%
3l9fA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 35.0 2.80e-01 71.1% 30.3%
1zhvA00 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.55 46.0 3.38e-01 100.0% 82.1%
5gkoA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 41.0 2.72e-01 93.3% 57.3%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 45.0 3.54e-01 100.0% 44.7%
4e1pA00 3.30.60.230 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain 0.53 40.0 3.82e-01 86.7% 85.5%
7xinA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 39.0 3.18e-01 91.1% 80.7%
5cygB00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.53 46.0 2.81e-01 95.6% 15.4%
7l9pK01 3.30.900.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain 0.52 40.0 3.09e-01 88.9% 89.1%
2kvkA00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.52 40.0 3.04e-01 97.8% 55.6%
3oqgA00 3.40.1440.50 Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › 0.52 41.0 2.95e-01 100.0% 46.0%
2giaA00 2.30.31.40 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › 0.52 46.0 3.17e-01 100.0% 42.9%
2mhyA00 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.51 35.0 3.32e-01 73.3% 80.7%
3wa7A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 38.0 2.32e-01 100.0% 34.3%
3g1jA00 2.30.30.350 Mainly Beta › Roll › SH3 type barrels. › mobile metagenome of vibrio cholerae. Integron cassette protein vch_cass4. 0.50 39.0 3.32e-01 97.8% 51.1%
2b0aA00 3.50.30.50 Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › Putative cyclase 0.50 37.0 2.53e-01 82.2% 71.0%
ECOD (69)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3331331 252.2.1.1 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.95 86.0 6.42e-01 100.0% 44.0%
3827127 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.95 86.0 6.53e-01 100.0% 46.3%
3813458 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.93 87.0 8.37e-01 100.0% 92.0%
3468885 252.2.1.1 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.93 86.0 6.94e-01 100.0% 58.7%
3965886 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.93 76.0 7.70e-01 88.9% 88.9%
3831192 252.2.1.1 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.91 84.0 6.65e-01 100.0% 54.1%
3682141 4325.1.1.0 mixed a+b and a/b › YegP-like › YegP-like › YegP-like 0.91 85.0 8.14e-01 100.0% 92.0%
3425673 252.2.1.1 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.91 77.0 7.39e-01 91.1% 84.0%
3380188 252.2.1.1 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.90 83.0 7.69e-01 100.0% 83.6%
3671921 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.88 82.0 7.56e-01 100.0% 81.8%
3661849 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.88 80.0 7.07e-01 100.0% 71.4%
3334492 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.86 79.0 6.39e-01 100.0% 72.5%
4024768 330.3.1.7 a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like › AP2 0.85 76.0 7.04e-01 97.8% 92.7%
4027687 330.3.1.0 a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like 0.83 73.0 6.81e-01 95.6% 90.9%
3743176 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.80 45.0 3.09e-01 100.0% 17.9%
4029439 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.77 69.0 5.89e-01 97.8% 73.9%
4028791 252.2.1.1 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.77 67.0 6.28e-01 97.8% 90.9%
4995243 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.76 55.0 4.62e-01 77.8% 88.0%
3959171 4029.1.1.0 a+b duplicates or obligate multimers › SSH domain in siroheme synthase middle domains-like › SSH domain in siroheme synthase middle domains-like › SSH domain in siroheme synthase middle domains-like 0.76 58.0 6.07e-01 88.9% 97.5%
5008107 101.1.2.15 alpha arrays › HTH › HTH › winged helix domain › MarR 0.74 44.0 3.27e-01 97.8% 25.7%
5082053 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 55.0 3.42e-01 86.7% 14.2%
5041477 375.1.3.3 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184 › DUF5817 0.73 53.0 4.82e-01 77.8% 100.0%
3281041 301.13.1.1 a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain › DegV 0.73 64.0 4.58e-01 100.0% 48.5%
3962875 301.13.1.1 a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain › DegV 0.72 62.0 4.50e-01 100.0% 48.5%
4944239 301.13.1.0 a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain 0.72 61.0 4.45e-01 100.0% 48.5%
2162577 301.13.1.1 a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain › DegV 0.71 61.0 4.40e-01 100.0% 47.0%
3678841 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.71 61.0 4.99e-01 100.0% 51.8%
4959767 375.1.3.3 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184 › DUF5817 0.70 50.0 4.61e-01 77.8% 100.0%
3319893 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.70 60.0 4.65e-01 100.0% 44.0%
3327575 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.69 61.0 4.74e-01 100.0% 48.0%
3305941 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.69 61.0 4.46e-01 100.0% 39.2%
4134161 301.13.1.1 a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain › DegV 0.69 58.0 4.23e-01 100.0% 47.4%
3299579 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.68 60.0 5.17e-01 100.0% 67.1%
3466238 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.68 46.0 2.64e-01 71.1% 31.3%
4946414 301.13.1.0 a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain 0.68 58.0 4.28e-01 100.0% 51.2%
4965210 304.163.1.0 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.67 50.0 4.64e-01 84.4% 83.3%
5048696 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.67 48.0 3.33e-01 80.0% 38.2%
3700687 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.66 46.0 2.87e-01 73.3% 74.9%
4986859 862.1.1.5 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol 0.66 55.0 3.39e-01 97.8% 28.5%
3589192 101.1.1.68 alpha arrays › HTH › HTH › Three-helical HTH › HTH_38 0.65 38.0 3.17e-01 100.0% 32.5%
4027686 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.65 53.0 5.04e-01 97.8% 92.7%
3348638 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.65 55.0 4.21e-01 100.0% 53.0%
3214873 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.62 51.0 3.46e-01 97.8% 41.1%
3639719 304.8.1.10 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_7 0.61 46.0 3.88e-01 84.4% 80.0%
943 220.1.1.47 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_16 0.61 52.0 4.06e-01 100.0% 44.0%
2755642 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.61 45.0 3.08e-01 91.1% 44.7%
3581101 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.61 49.0 3.43e-01 95.6% 42.9%
3970771 3009.1.1.0 alpha arrays › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like 0.60 44.0 3.01e-01 84.4% 99.0%
3798470 2011.2.1.0 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like 0.60 52.0 3.20e-01 100.0% 59.3%
4437052 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.58 49.0 3.42e-01 93.3% 60.0%
5074130 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.58 48.0 3.00e-01 93.3% 50.2%
3925891 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.58 48.0 3.78e-01 100.0% 45.6%
3983196 2498.1.1.57 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › LPD1 0.58 51.0 3.24e-01 100.0% 20.9%
3946113 241.7.1.1 a+b two layers › Type III secretory system chaperone-like › YgaC/TfoX-N like › YgaC/TfoX-N like › TfoX_N 0.58 52.0 3.89e-01 100.0% 95.2%
3968902 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.56 43.0 2.86e-01 95.6% 32.9%
4541289 2002.1.1.154 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Meth_synt_1 0.55 47.0 2.76e-01 100.0% 23.1%
3446412 109.4.1.95 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 0.54 47.0 2.77e-01 100.0% 12.9%
3494392 3937.1.1.2 alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin 0.54 45.0 2.64e-01 91.1% 51.1%
3791945 5054.1.1.2 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.54 47.0 3.03e-01 100.0% 43.1%
5060792 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.53 48.0 3.43e-01 100.0% 75.0%
5003912 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 40.0 2.91e-01 88.9% 95.0%
3710998 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 47.0 2.69e-01 100.0% 62.3%
4088600 318.1.1.1 a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6 0.53 43.0 3.66e-01 100.0% 76.5%
4505972 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.53 43.0 2.52e-01 95.6% 12.2%
None 0.53 42.0 3.02e-01 91.1% 45.3%
4483596 2007.6.1.3 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › PGI 0.52 46.0 2.87e-01 100.0% 31.4%
5028281 2007.1.1.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like 0.52 45.0 3.10e-01 100.0% 68.8%
4955694 2498.2.1.0 mixed a+b and a/b › Zincin-like › beta-N-acetylhexosaminidase-like domain › beta-N-acetylhexosaminidase-like domain 0.52 43.0 3.21e-01 97.8% 88.0%
4081606 6094.1.1.0 a+b two layers › KS-MAT linker domain in fatty acid synthase › KS-MAT linker domain in fatty acid synthase › KS-MAT linker domain in fatty acid synthase 0.51 38.0 3.18e-01 84.4% 44.7%
D3 high residues 171-237
PDB
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4wxaA00 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.74 52.0 4.82e-01 73.1% 98.8%
1h10A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.73 53.0 4.39e-01 77.6% 45.3%
1js3A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.69 47.0 4.08e-01 70.1% 100.0%
1txdA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.68 47.0 3.89e-01 76.1% 40.5%
2nyxB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.67 49.0 3.84e-01 77.6% 85.9%
3nyiA02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.67 60.0 4.71e-01 100.0% 89.8%
3agkA02 3.30.420.60 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 0.65 50.0 4.04e-01 80.6% 73.4%
2j3tD01 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.65 47.0 3.78e-01 77.6% 38.8%
3tqfA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 48.0 3.66e-01 80.6% 90.3%
7t8tA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.64 47.0 3.84e-01 79.1% 51.1%
1pzxA03 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.64 50.0 4.18e-01 86.6% 95.1%
3fehA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.61 54.0 4.42e-01 100.0% 53.2%
2yhaA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.61 52.0 3.69e-01 100.0% 34.5%
1jgsA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 43.0 3.42e-01 74.6% 71.0%
1mgpA02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.60 53.0 4.35e-01 97.0% 93.4%
5ttjA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.60 43.0 2.97e-01 74.6% 36.7%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 42.0 3.53e-01 80.6% 45.0%
2innB00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.60 50.0 2.99e-01 91.0% 40.8%
3k1hA00 3.30.1120.180 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 0.60 46.0 3.82e-01 82.1% 79.1%
7dvrA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 41.0 3.19e-01 71.6% 68.1%
2dt8A02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.59 53.0 4.26e-01 100.0% 92.3%
2r7rA05 1.10.357.80 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.59 44.0 3.28e-01 80.6% 71.0%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.59 47.0 3.99e-01 88.1% 54.3%
3ga8A00 3.10.20.860 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.59 40.0 4.09e-01 71.6% 86.6%
3nwnA00 3.40.850.10 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain 0.58 50.0 3.33e-01 100.0% 39.3%
1b8pA02 3.90.110.10 Alpha Beta › Alpha-Beta Complex › L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2 › Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal 0.54 42.0 3.13e-01 83.6% 83.1%
3qthB00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.54 48.0 3.61e-01 100.0% 86.6%
2g7zA02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.54 47.0 3.94e-01 100.0% 92.5%
2rdpA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 48.0 3.74e-01 98.5% 67.1%
2zihC00 1.10.3630.10 Mainly Alpha › Orthogonal Bundle › yeast vps74-n-term truncation variant fold › yeast vps74-n-term truncation variant domain like 0.53 40.0 2.64e-01 80.6% 29.7%
5dymA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 37.0 3.33e-01 76.1% 91.7%
5cygB00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.52 40.0 2.61e-01 82.1% 72.5%
2fbiA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 38.0 3.11e-01 80.6% 72.1%
6fndA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 43.0 3.08e-01 89.6% 72.6%
2h84A02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.51 37.0 2.95e-01 77.6% 85.1%
5h20A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 39.0 3.37e-01 80.6% 80.6%
3l60A01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.50 44.0 3.09e-01 98.5% 43.2%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3813458 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.90 61.0 7.05e-01 70.1% 94.0%
3827127 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.84 61.0 5.30e-01 100.0% 52.6%
4149276 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.74 52.0 3.82e-01 100.0% 29.7%
4091699 857.1.1.1 a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.71 46.0 4.08e-01 70.1% 45.0%
4028791 252.2.1.1 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.70 50.0 5.47e-01 100.0% 92.7%
3678841 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.68 50.0 4.63e-01 77.6% 61.2%
3305941 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.68 59.0 4.81e-01 94.0% 69.2%
3591115 304.163.1.0 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.67 46.0 4.01e-01 76.1% 47.0%
3466238 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.67 46.0 2.72e-01 88.1% 10.4%
5065366 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.67 52.0 4.32e-01 85.1% 54.2%
2327277 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.66 45.0 3.55e-01 71.6% 94.5%
3925367 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.66 47.0 3.61e-01 80.6% 34.0%
2755642 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.65 46.0 3.26e-01 100.0% 24.0%
3577911 220.1.1.15 beta barrels › PH domain-like › PH domain-like › PH domain-like › BBL5 0.65 50.0 3.98e-01 85.1% 44.8%
182769 2004.1.2.3 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › PEP carboxykinase catalytic C-terminal domain › Hpr_kinase_C 0.65 48.0 3.66e-01 80.6% 90.3%
3299579 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.64 51.0 5.03e-01 88.1% 81.4%
4129936 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.63 50.0 4.43e-01 85.1% 71.6%
4027686 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.63 45.0 4.88e-01 100.0% 92.7%
3905168 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.63 56.0 4.48e-01 100.0% 50.8%
3710998 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.63 48.0 2.86e-01 82.1% 29.8%
5077851 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.63 45.0 3.46e-01 76.1% 84.7%
4952992 101.1.2.135 alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.62 47.0 3.59e-01 79.1% 63.3%
3288926 101.1.2.15 alpha arrays › HTH › HTH › winged helix domain › MarR 0.62 45.0 3.49e-01 76.1% 63.4%
4946000 213.1.1.0 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.62 48.0 3.83e-01 83.6% 61.2%
4997639 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.62 46.0 4.01e-01 80.6% 79.0%
4082847 101.1.2.15 alpha arrays › HTH › HTH › winged helix domain › MarR 0.62 44.0 3.43e-01 74.6% 69.3%
3946113 241.7.1.1 a+b two layers › Type III secretory system chaperone-like › YgaC/TfoX-N like › YgaC/TfoX-N like › TfoX_N 0.60 41.0 3.47e-01 70.1% 96.2%
4974958 2004.1.2.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › PEP carboxykinase catalytic C-terminal domain 0.60 47.0 2.93e-01 85.1% 54.8%
4541289 2002.1.1.154 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Meth_synt_1 0.60 43.0 2.74e-01 79.1% 37.9%
3700687 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.60 45.0 3.06e-01 80.6% 69.0%
3319893 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.60 49.0 4.31e-01 91.0% 70.0%
4946414 301.13.1.0 a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain 0.59 52.0 4.28e-01 100.0% 94.3%
5035395 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.59 51.0 3.77e-01 95.5% 87.1%
5041715 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.58 45.0 3.79e-01 82.1% 59.1%
4134161 301.13.1.1 a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain › DegV 0.58 50.0 3.97e-01 97.0% 95.6%
3056876 167.1.1.0 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 0.58 45.0 3.78e-01 83.6% 54.5%
2979134 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.57 45.0 3.77e-01 83.6% 54.5%
3581101 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.57 48.0 3.59e-01 94.0% 56.5%
3805761 614.1.1.0 alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain 0.57 43.0 4.12e-01 80.6% 70.7%
4505972 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.57 40.0 2.64e-01 74.6% 21.6%
4012962 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 43.0 3.02e-01 80.6% 46.2%
4094652 2004.1.2.3 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › PEP carboxykinase catalytic C-terminal domain › Hpr_kinase_C 0.56 39.0 2.95e-01 74.6% 77.8%
3991544 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.56 46.0 3.94e-01 86.6% 69.0%
3998628 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.56 38.0 2.91e-01 71.6% 41.2%
3484000 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.56 45.0 2.52e-01 97.0% 96.3%
3935332 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.55 42.0 3.32e-01 82.1% 41.5%
3581467 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.55 46.0 3.65e-01 100.0% 46.9%
3781435 601.7.1.12 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › SWT1_3rd 0.54 46.0 3.71e-01 98.5% 92.9%
3684015 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.54 45.0 3.88e-01 89.6% 65.0%
4928083 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.54 41.0 2.74e-01 97.0% 20.0%
3208120 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.54 45.0 3.40e-01 91.0% 41.3%
4254768 2004.1.2.3 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › PEP carboxykinase catalytic C-terminal domain › Hpr_kinase_C 0.53 36.0 2.66e-01 70.1% 34.4%
3958996 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 38.0 2.65e-01 77.6% 22.9%
3625789 229.1.1.0 a+b two layers › Cdc48 domain 2-like › Cdc48 domain 2-like › Cdc48 domain 2-like 0.53 31.0 2.75e-01 85.1% 39.0%
4940484 244.1.1.0 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.52 45.0 4.25e-01 95.5% 98.8%
3920672 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.52 43.0 3.90e-01 88.1% 68.9%
3367818 109.4.1.1272 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, E_motif 0.52 44.0 2.62e-01 95.5% 12.9%
3236725 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.51 43.0 2.96e-01 97.0% 66.2%