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IMGVR_UViG_3300037454_000906-3300037454-Ga0394156_0000018_146708_148780

Arc-Vir

IMGVR_UViG_3300037454_000906-3300037454-Ga0394156_0000018_146708_148780

Quality

78.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 215-301
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01541.31 best GIY-YIG 22.7 1.40e-04 95.4% 50.0%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ln0A00 3.40.1440.10 Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease 0.79 72.0 7.08e-01 97.7% 95.7%
1yd0A00 3.40.1440.10 Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease 0.73 58.0 5.80e-01 98.9% 83.1%
3oqgA00 3.40.1440.50 Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › 0.71 50.0 3.95e-01 73.6% 42.0%
1uc6A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.70 42.0 3.93e-01 82.8% 48.6%
4dohE02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.69 41.0 3.82e-01 77.0% 47.2%
3hvnA01 3.90.840.10 Alpha Beta › Alpha-Beta Complex › HIV-1 Reverse Transcriptase; Chain A, domain 3 › Thiol-activated cytolysin superfamily/Thiol-activated cytolysin, alpha-beta domain 0.64 45.0 3.64e-01 73.6% 41.9%
1wfnA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 38.0 3.81e-01 83.9% 60.2%
4a18X01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.58 40.0 4.23e-01 73.6% 78.5%
2jxtA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.57 40.0 4.23e-01 80.5% 85.5%
1vwxS02 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.57 41.0 4.28e-01 89.7% 88.2%
4rdbA01 2.60.40.2580 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 44.0 3.71e-01 95.4% 50.3%
6usmB01 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.55 45.0 3.87e-01 93.1% 98.6%
1xffA00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.54 48.0 3.52e-01 98.9% 58.0%
ECOD (51)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
77927 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.79 72.0 7.04e-01 98.9% 94.7%
4677975 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.78 71.0 6.40e-01 98.9% 76.3%
3582540 821.1.1.0 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease 0.77 69.0 6.53e-01 97.7% 98.1%
4236834 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.77 62.0 6.30e-01 98.9% 88.2%
3965455 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.76 62.0 6.15e-01 96.6% 83.3%
4310838 821.1.1.9 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › PF30054 0.74 60.0 6.14e-01 98.9% 89.4%
4977317 821.1.1.9 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › PF30054 0.74 61.0 5.44e-01 98.9% 64.7%
4515517 821.1.1.9 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › PF30054 0.73 60.0 5.98e-01 98.9% 85.6%
3588392 821.1.1.9 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › PF30054 0.72 59.0 5.70e-01 98.9% 78.0%
5053865 821.1.1.0 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease 0.71 59.0 5.83e-01 95.4% 85.6%
3467170 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.70 49.0 5.58e-01 81.6% 100.0%
4100104 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.69 62.0 4.55e-01 98.9% 43.5%
4001737 11.1.1.888 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3, DB 0.69 42.0 3.08e-01 82.8% 23.6%
3363261 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.69 61.0 5.25e-01 97.7% 75.6%
4398485 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.68 61.0 4.35e-01 97.7% 36.3%
4138617 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.68 61.0 4.58e-01 98.9% 43.4%
4160981 821.1.1.1 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.68 61.0 4.55e-01 98.9% 51.9%
3841255 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.67 43.0 4.20e-01 82.8% 60.0%
3975705 3115.6.1.0 a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon 0.63 36.0 4.54e-01 82.8% 100.0%
4007508 3115.6.1.2 a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597 0.62 36.0 4.50e-01 82.8% 100.0%
5065792 301.1.1.2 a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.62 47.0 3.86e-01 79.3% 56.8%
3403311 4326.1.1.1 a+b two layers › ERH-like › ERH-like › ERH-like › ER 0.62 43.0 4.07e-01 70.1% 74.0%
2896602 4326.1.1.1 a+b two layers › ERH-like › ERH-like › ERH-like › ER 0.62 42.0 4.05e-01 70.1% 74.0%
3274047 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.62 46.0 4.38e-01 98.9% 68.0%
4969863 3115.1.1.1 a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.61 43.0 4.55e-01 80.5% 85.3%
5027350 301.1.1.2 a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.58 43.0 3.75e-01 79.3% 64.5%
4939878 230.6.1.1 a+b two layers › T-fold › 40S ribosomal protein S3A C-terminal domain › 40S ribosomal protein S3A C-terminal domain › Ribosomal_S3Ae 0.58 41.0 3.70e-01 74.7% 69.6%
4394244 230.6.1.1 a+b two layers › T-fold › 40S ribosomal protein S3A C-terminal domain › 40S ribosomal protein S3A C-terminal domain › Ribosomal_S3Ae 0.58 40.0 3.70e-01 72.4% 73.0%
4996552 3115.1.1.1 a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.57 41.0 4.15e-01 81.6% 77.6%
5039135 230.6.1.1 a+b two layers › T-fold › 40S ribosomal protein S3A C-terminal domain › 40S ribosomal protein S3A C-terminal domain › Ribosomal_S3Ae 0.57 40.0 3.80e-01 73.6% 79.0%
4600902 230.6.1.0 a+b two layers › T-fold › 40S ribosomal protein S3A C-terminal domain › 40S ribosomal protein S3A C-terminal domain 0.57 39.0 3.75e-01 72.4% 80.0%
4013514 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.57 41.0 3.94e-01 85.1% 64.8%
5067865 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.57 40.0 4.29e-01 80.5% 92.9%
5046273 230.6.1.1 a+b two layers › T-fold › 40S ribosomal protein S3A C-terminal domain › 40S ribosomal protein S3A C-terminal domain › Ribosomal_S3Ae 0.56 40.0 3.75e-01 77.0% 78.1%
3903750 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 37.0 3.52e-01 82.8% 56.2%
5065436 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.56 38.0 4.21e-01 75.9% 95.3%
4967222 3115.1.1.1 a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.56 37.0 4.19e-01 70.1% 100.0%
3231920 11.10.1.4 beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like › TRAF-mep_MATH 0.56 39.0 3.06e-01 72.4% 41.1%
5030993 3115.1.1.1 a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.56 40.0 4.13e-01 85.1% 83.7%
3621921 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.55 42.0 4.50e-01 98.9% 97.3%
4942818 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.55 37.0 3.23e-01 70.1% 47.9%
3588533 868.1.1.1 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH 0.54 45.0 3.54e-01 93.1% 79.5%
4196175 230.6.1.1 a+b two layers › T-fold › 40S ribosomal protein S3A C-terminal domain › 40S ribosomal protein S3A C-terminal domain › Ribosomal_S3Ae 0.54 37.0 3.58e-01 73.6% 75.2%
4951473 3115.1.1.1 a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.54 37.0 4.04e-01 72.4% 98.4%
3896560 301.1.1.2 a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.53 40.0 3.29e-01 81.6% 61.2%
4961328 206.1.1.267 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › IucA_IucC 0.53 42.0 2.76e-01 89.7% 37.7%
3196133 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.53 44.0 3.11e-01 97.7% 46.9%
4942649 230.6.1.1 a+b two layers › T-fold › 40S ribosomal protein S3A C-terminal domain › 40S ribosomal protein S3A C-terminal domain › Ribosomal_S3Ae 0.52 35.0 3.39e-01 71.3% 77.1%
4029338 2003.1.2.15 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.51 42.0 2.62e-01 92.0% 68.1%
5073588 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.50 39.0 2.90e-01 96.6% 29.5%
3502029 210.2.1.1 a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C 0.50 39.0 2.59e-01 88.5% 28.8%
D2 high residues 421-485
PDB
D3 high residues 638-686
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF22083.3 best I-HmuI_NUMOD-like 37.2 2.30e-09 93.9% 82.6%
D4 medium residues 164-214
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gomA00 1.10.10.1270 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sbi, C3 binding domain IV 0.56 43.0 4.18e-01 90.2% 86.9%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3262288 4030.1.1.0 alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.63 49.0 4.73e-01 90.2% 78.3%
4962699 101.1.2.924 alpha arrays › HTH › HTH › winged helix domain › DUF7342 0.58 46.0 3.31e-01 90.2% 30.3%
3363484 101.1.8.0 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.57 48.0 4.20e-01 100.0% 71.8%
D5 medium residues 492-549
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF22083.3 best I-HmuI_NUMOD-like 33.6 3.30e-08 72.4% 76.1%
PF07453.20 NUMOD1 41.1 2.10e-10 63.8% 91.9%
D6 medium residues 566-621
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07453.20 best NUMOD1 22.1 1.90e-04 62.5% 91.9%
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u3eM02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.89 77.0 7.12e-01 92.9% 75.0%
2grgA01 3.40.1840.10 Alpha Beta › 3-Layer(aba) Sandwich › Profilin-like › YNR034W-A-like 0.59 43.0 3.91e-01 82.1% 79.5%
2ixsA02 3.40.1350.80 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › BsuBI/PstI restriction endonuclease, C-terminal domain 0.56 39.0 2.89e-01 75.0% 48.1%
2djpA00 3.10.350.10 Alpha Beta › Roll › Membrane-bound Lytic Murein Transglycosylase D; Chain A › LysM domain 0.56 40.0 3.64e-01 91.1% 55.8%
2xi8A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.56 50.0 4.71e-01 98.2% 84.8%
1e0gA00 3.10.350.10 Alpha Beta › Roll › Membrane-bound Lytic Murein Transglycosylase D; Chain A › LysM domain 0.55 37.0 3.90e-01 92.9% 83.3%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2876 101.1.14.2 alpha arrays › HTH › HTH › DNA-binding domain of intron-encoded endonucleases › I-HmuI_NUMOD-like 0.89 77.0 7.08e-01 92.9% 73.9%
4384880 101.1.14.3 alpha arrays › HTH › HTH › DNA-binding domain of intron-encoded endonucleases › NUMOD1 0.88 73.0 6.25e-01 89.3% 60.0%
4414927 101.1.14.3 alpha arrays › HTH › HTH › DNA-binding domain of intron-encoded endonucleases › NUMOD1 0.83 71.0 6.62e-01 94.6% 75.4%
3171408 101.1.14.3 alpha arrays › HTH › HTH › DNA-binding domain of intron-encoded endonucleases › NUMOD1 0.81 67.0 6.98e-01 92.9% 100.0%
3587703 101.1.14.0 alpha arrays › HTH › HTH › DNA-binding domain of intron-encoded endonucleases 0.80 65.0 6.86e-01 92.9% 100.0%
3691772 101.15.1.1 alpha arrays › HTH › LysM domain › LysM domain › LysM 0.61 44.0 4.43e-01 75.0% 87.3%
4468802 101.15.1.0 alpha arrays › HTH › LysM domain › LysM domain 0.59 43.0 3.81e-01 76.8% 60.8%
3296049 4121.1.1.2 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like 0.59 49.0 3.36e-01 100.0% 35.7%
4968600 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.57 47.0 3.85e-01 96.4% 51.0%
3548207 221.4.1.6 a+b two layers › beta-Grasp › Nudix › Nudix › NUDIX-like 0.53 44.0 3.40e-01 100.0% 74.5%