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IMGVR_UViG_3300037673_000034-3300037673-Ga0314854_000381_27226_27777
Arc-VirIMGVR_UViG_3300037673_000034-3300037673-Ga0314854_000381_27226_27777
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-75
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3keyA01 | 1.10.10.1080 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain | 0.67 | 48.0 | 4.64e-01 | 77.3% | 65.5% |
| 3umbA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.67 | 46.0 | 4.61e-01 | 72.0% | 70.9% |
| 3k92A01 | 1.10.8.1210 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.65 | 35.0 | 3.94e-01 | 89.3% | 66.7% |
| 3bg2A03 | 1.10.3410.10 | Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain | 0.59 | 45.0 | 4.25e-01 | 88.0% | 91.7% |
| 3wd6A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 41.0 | 3.52e-01 | 73.3% | 51.7% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.58 | 42.0 | 4.31e-01 | 77.3% | 97.3% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.57 | 39.0 | 3.32e-01 | 70.7% | 81.6% |
| 4gltA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 40.0 | 3.51e-01 | 73.3% | 58.8% |
| 2gbbB00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.57 | 45.0 | 3.60e-01 | 85.3% | 46.5% |
| 2pusA04 | 6.10.140.300 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 41.0 | 3.56e-01 | 74.7% | 59.3% |
| 3ed5A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.56 | 41.0 | 4.06e-01 | 81.3% | 92.9% |
| 2kbwA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.56 | 41.0 | 3.36e-01 | 80.0% | 96.1% |
| 2b5dX02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.56 | 46.0 | 4.04e-01 | 90.7% | 81.6% |
| 1a5kC02 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.54 | 43.0 | 2.81e-01 | 90.7% | 96.1% |
| 3hhcC00 | 1.20.1250.60 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda | 0.54 | 39.0 | 3.13e-01 | 76.0% | 62.9% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 42.0 | 3.80e-01 | 89.3% | 61.8% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.53 | 43.0 | 3.67e-01 | 90.7% | 63.4% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 39.0 | 3.24e-01 | 78.7% | 97.0% |
| 3buxB01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.52 | 43.0 | 3.68e-01 | 94.7% | 67.4% |
| 3vnxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 42.0 | 3.17e-01 | 93.3% | 54.4% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3705680 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 40.0 | 3.70e-01 | 74.7% | 44.2% |
| 5013005 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.68 | 54.0 | 4.03e-01 | 85.3% | 41.6% |
| 3861204 | 103.4.1.2 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › TFIIS_M | 0.67 | 56.0 | 4.90e-01 | 90.7% | 65.5% |
| 3195747 | 3788.1.1.0 ↗ | alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) | 0.66 | 49.0 | 5.08e-01 | 80.0% | 91.4% |
| 4662975 | 589.1.2.0 ↗ | alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › TF C-terminus (Pfam 05698) | 0.64 | 52.0 | 4.07e-01 | 90.7% | 66.1% |
| 3739207 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.63 | 47.0 | 4.40e-01 | 80.0% | 66.3% |
| 2561785 | 859.1.1.5 ↗ | a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › bacHORMA_2 | 0.62 | 51.0 | 3.91e-01 | 89.3% | 91.7% |
| 4200953 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.62 | 42.0 | 3.36e-01 | 70.7% | 94.8% |
| 4990639 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.59 | 47.0 | 3.21e-01 | 86.7% | 65.2% |
| 4339225 | 101.1.4.0 ↗ | alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like | 0.58 | 48.0 | 4.59e-01 | 89.3% | 94.1% |
| 3791227 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.57 | 42.0 | 4.24e-01 | 90.7% | 76.9% |
| 4011783 | 633.21.1.25 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF7598 | 0.57 | 41.0 | 3.27e-01 | 76.0% | 72.9% |
| 4998576 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.57 | 40.0 | 4.00e-01 | 73.3% | 82.7% |
| 3934901 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.56 | 45.0 | 3.38e-01 | 90.7% | 93.7% |
| 1954445 | 864.1.1.2 ↗ | a+b two layers › DLC › DLC › DLC › Tctex-1 | 0.55 | 38.0 | 3.78e-01 | 76.0% | 67.1% |
| 4945748 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.54 | 44.0 | 4.20e-01 | 90.7% | 95.6% |
| 4071210 | 5039.1.1.1 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 | 0.53 | 43.0 | 2.95e-01 | 88.0% | 31.1% |
| 3690980 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.52 | 41.0 | 3.79e-01 | 90.7% | 64.8% |
| 3619437 | 5073.1.1.0 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M | 0.52 | 45.0 | 2.73e-01 | 98.7% | 44.4% |
| 4032746 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.51 | 39.0 | 3.07e-01 | 85.3% | 48.2% |
| 3760270 | 2008.1.1.94 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF5614 | 0.50 | 39.0 | 4.04e-01 | 82.7% | 98.6% |
| 4978416 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.50 | 39.0 | 3.66e-01 | 88.0% | 88.4% |
D2
medium
residues 76-181
Domain cluster:
rep: IMGVR_UViG_3300025859_001166-3300025859-Ga0209096_100026138__D12-148
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1eyuA00 | 3.40.210.10 | Alpha Beta › 3-Layer(aba) Sandwich › PvuII Endonuclease; Chain A › PVUII Endonuclease, subunit A | 0.64 | 56.0 | 4.93e-01 | 95.3% | 67.3% |
| 3ajvC02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.64 | 40.0 | 4.34e-01 | 72.6% | 73.6% |
| 1b96A00 | 3.40.600.10 | Alpha Beta › 3-Layer(aba) Sandwich › ECO RV Endonuclease; Chain A › DNA mismatch repair MutH/Restriction endonuclease, type II | 0.62 | 53.0 | 4.08e-01 | 95.3% | 55.7% |
| 3ndhA00 | 3.40.600.30 | Alpha Beta › 3-Layer(aba) Sandwich › ECO RV Endonuclease; Chain A › | 0.60 | 52.0 | 4.17e-01 | 95.3% | 54.7% |
| 4ftfA00 | 3.30.300.250 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.60 | 42.0 | 4.17e-01 | 71.7% | 86.2% |
| 4oc8A01 | 2.30.280.20 | Mainly Beta › Roll › PUA domain-like › | 0.59 | 51.0 | 4.03e-01 | 94.3% | 70.2% |
| 8d3mI01 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.58 | 44.0 | 3.57e-01 | 81.1% | 59.4% |
| 2b78A01 | 2.30.130.10 | Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › PUA domain | 0.57 | 36.0 | 4.30e-01 | 78.3% | 100.0% |
| 3sm4A00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.57 | 42.0 | 3.34e-01 | 78.3% | 81.8% |
| 5dnoA00 | 3.10.590.10 | Alpha Beta › Roll › ph1033 like fold › ph1033 like domains | 0.57 | 49.0 | 4.26e-01 | 95.3% | 80.5% |
| 4hn3A00 | 3.10.570.10 | Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain | 0.57 | 50.0 | 3.51e-01 | 97.2% | 59.3% |
| 4ic1D00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.55 | 43.0 | 3.49e-01 | 83.0% | 51.5% |
| 3tqtB01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.55 | 42.0 | 4.10e-01 | 85.8% | 73.1% |
| 2gw6A01 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.54 | 38.0 | 3.71e-01 | 72.6% | 92.2% |
| 3s9xA00 | 3.10.400.10 | Alpha Beta › Roll › Sulfate adenylyltransferase › Sulfate adenylyltransferase | 0.54 | 44.0 | 3.90e-01 | 90.6% | 98.7% |
| 6vbkA01 | 2.30.130.40 | Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like | 0.53 | 43.0 | 4.30e-01 | 88.7% | 100.0% |
| 3k3pA01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 35.0 | 3.48e-01 | 80.2% | 64.0% |
| 2kcqA00 | 3.40.140.10 | Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 | 0.53 | 46.0 | 4.06e-01 | 94.3% | 75.8% |
| 1e4eA03 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 39.0 | 3.74e-01 | 85.8% | 70.8% |
| 3eeqA01 | 3.40.50.11220 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 33.0 | 3.20e-01 | 100.0% | 57.5% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4284098 | 2008.1.1.198 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF6998 | 0.70 | 52.0 | 4.86e-01 | 94.3% | 63.1% |
| 4967615 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.67 | 59.0 | 5.01e-01 | 97.2% | 75.4% |
| 5005296 | 2008.1.1.232 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF25941 | 0.64 | 54.0 | 5.18e-01 | 92.5% | 81.7% |
| 1933320 | 2008.1.1.76 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › SwaI-like | 0.64 | 54.0 | 4.27e-01 | 94.3% | 49.6% |
| 4981806 | 1.1.9.31 ↗ | beta barrels › cradle loop barrel › RIFT-related › PUA domain › SRA_ScoMcrA | 0.62 | 54.0 | 5.01e-01 | 95.3% | 79.3% |
| 138445 | 2003.1.10.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain › Dala_Dala_lig_N | 0.61 | 31.0 | 4.21e-01 | 82.1% | 100.0% |
| 5063788 | 1.1.9.3 ↗ | beta barrels › cradle loop barrel › RIFT-related › PUA domain › EVE | 0.61 | 50.0 | 4.28e-01 | 89.6% | 92.0% |
| 4964155 | 1.1.9.31 ↗ | beta barrels › cradle loop barrel › RIFT-related › PUA domain › SRA_ScoMcrA | 0.60 | 52.0 | 4.74e-01 | 95.3% | 77.1% |
| 3981315 | 327.7.1.16 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › T6SS_TssF | 0.60 | 42.0 | 3.71e-01 | 72.6% | 76.1% |
| 1145719 | 2008.1.1.62 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ThaI | 0.59 | 52.0 | 4.16e-01 | 96.2% | 56.5% |
| 4960637 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.59 | 41.0 | 4.37e-01 | 70.8% | 100.0% |
| 3607934 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.59 | 47.0 | 3.96e-01 | 85.8% | 67.0% |
| 3418432 | 1.1.9.3 ↗ | beta barrels › cradle loop barrel › RIFT-related › PUA domain › EVE | 0.58 | 45.0 | 4.61e-01 | 84.9% | 93.3% |
| 3801626 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.57 | 47.0 | 4.70e-01 | 89.6% | 98.2% |
| 3610562 | 2492.1.1.11 ↗ | a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › NPL4 | 0.56 | 47.0 | 3.68e-01 | 92.5% | 69.4% |
| 3924247 | 1143.1.1.1 ↗ | beta sandwiches › beta sandwich domain in acetophenone carboxylase (Apc) alpha subunit › beta sandwich domain in acetophenone carboxylase (Apc) alpha subunit › beta sandwich domain in acetophenone carboxylase (Apc) alpha subunit › Hydant_A_C | 0.55 | 32.0 | 3.71e-01 | 88.7% | 81.3% |
| 4317475 | 1143.1.1.1 ↗ | beta sandwiches › beta sandwich domain in acetophenone carboxylase (Apc) alpha subunit › beta sandwich domain in acetophenone carboxylase (Apc) alpha subunit › beta sandwich domain in acetophenone carboxylase (Apc) alpha subunit › Hydant_A_C | 0.55 | 32.0 | 3.59e-01 | 88.7% | 75.0% |
| 4457853 | 3585.1.1.0 ↗ | a+b two layers › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain | 0.53 | 33.0 | 3.84e-01 | 85.8% | 88.0% |
| 133840 | 2492.1.1.18 ↗ | a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › Prok-JAB | 0.53 | 46.0 | 4.13e-01 | 94.3% | 80.0% |
| 3737487 | 242.3.1.1 ↗ | a+b two layers › Homing endonucleases-like › DNA repair protein MutS, domain I › DNA repair protein MutS, domain I › MutS_I | 0.52 | 32.0 | 3.08e-01 | 95.3% | 50.4% |
| 4480171 | 2003.1.10.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain › Dala_Dala_lig_N | 0.52 | 39.0 | 4.11e-01 | 85.8% | 88.4% |
| 3640508 | 207.11.1.1 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD | 0.52 | 44.0 | 3.24e-01 | 93.4% | 78.5% |
| 4932437 | 1.1.9.14 ↗ | beta barrels › cradle loop barrel › RIFT-related › PUA domain › DUF3850 | 0.52 | 36.0 | 3.94e-01 | 72.6% | 100.0% |
| 3408439 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.51 | 42.0 | 2.79e-01 | 89.6% | 64.0% |
| 3242907 | 10.4.1.1 ↗ | beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › CUB | 0.51 | 34.0 | 3.38e-01 | 94.3% | 64.3% |
| 3668779 | 2492.1.1.26 ↗ | a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › MPN_2A_DUB_like | 0.50 | 43.0 | 3.58e-01 | 95.3% | 78.4% |