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IMGVR_UViG_3300037842_000514-3300037842-Ga0427874_000162_24822_26075
Arc-VirIMGVR_UViG_3300037842_000514-3300037842-Ga0427874_000162_24822_26075
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-55
Domain cluster:
rep: IMGVR_UViG_3300000153_000287-3300000153-SI39nov09_135mDRAFT_10034313__D5-55
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1dlwA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.82 | 76.0 | 5.79e-01 | 100.0% | 87.1% |
| 2yhsA01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.75 | 64.0 | 5.29e-01 | 100.0% | 53.6% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.73 | 62.0 | 4.57e-01 | 98.2% | 74.0% |
| 1ls1A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.72 | 63.0 | 5.34e-01 | 96.4% | 64.0% |
| 3b9qA01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.72 | 65.0 | 5.53e-01 | 100.0% | 64.0% |
| 6fhpD00 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.71 | 61.0 | 5.89e-01 | 98.2% | 90.3% |
| 3dtoA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.70 | 63.0 | 5.36e-01 | 100.0% | 97.7% |
| 2wy4A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.70 | 59.0 | 4.51e-01 | 100.0% | 81.3% |
| 2lo0A00 | 1.10.286.70 | Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › Get5 dimerization domain | 0.69 | 47.0 | 5.01e-01 | 70.9% | 93.3% |
| 1tt5B02 | 1.10.10.520 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ubiquitin activating enzymes (Uba3). Chain: B, domain 2 | 0.68 | 59.0 | 5.34e-01 | 100.0% | 94.8% |
| 3fdqA01 | 1.20.120.1030 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Motility repressor MogR, DNA-binding domain | 0.68 | 58.0 | 4.55e-01 | 98.2% | 89.3% |
| 1t98A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.67 | 57.0 | 4.90e-01 | 94.5% | 64.4% |
| 1v07A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.67 | 56.0 | 4.60e-01 | 98.2% | 98.2% |
| 3deeA01 | 1.10.150.690 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 | 0.67 | 56.0 | 4.92e-01 | 100.0% | 61.6% |
| 6t0bf00 | 1.25.40.40 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI | 0.66 | 54.0 | 4.35e-01 | 98.2% | 48.0% |
| 7jv7B01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.64 | 53.0 | 3.99e-01 | 98.2% | 42.5% |
| 3dfgA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.64 | 50.0 | 5.20e-01 | 92.7% | 100.0% |
| 4ol9A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.64 | 54.0 | 4.20e-01 | 98.2% | 50.4% |
| 3vayA02 | 1.20.120.1600 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 51.0 | 4.42e-01 | 98.2% | 73.6% |
| 5tqbB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 47.0 | 2.90e-01 | 89.1% | 14.5% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 50.0 | 4.15e-01 | 98.2% | 58.8% |
| 3mkqA03 | 1.25.40.470 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 42.0 | 2.86e-01 | 89.1% | 19.8% |
| 1sgmA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 45.0 | 3.25e-01 | 100.0% | 46.7% |
| 2olpA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 44.0 | 3.23e-01 | 96.4% | 61.6% |
| 2zxyA00 | 1.10.760.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain | 0.51 | 41.0 | 3.72e-01 | 98.2% | 67.4% |
| 6f7hA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.51 | 41.0 | 2.73e-01 | 92.7% | 81.7% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4479932 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.75 | 68.0 | 5.75e-01 | 100.0% | 62.2% |
| 3700574 | 568.1.1.2 ↗ | few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related › COX17 | 0.74 | 66.0 | 6.33e-01 | 100.0% | 90.6% |
| 4948728 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.73 | 63.0 | 5.15e-01 | 92.7% | 54.7% |
| 4938165 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.72 | 65.0 | 5.45e-01 | 100.0% | 67.8% |
| 3603904 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.72 | 63.0 | 5.30e-01 | 96.4% | 63.3% |
| 4929833 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.70 | 64.0 | 5.36e-01 | 100.0% | 63.3% |
| 4990634 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.70 | 63.0 | 5.31e-01 | 100.0% | 67.8% |
| 3741068 | 6076.1.1.0 ↗ | alpha arrays › Catalytic cysteine domain in ubiquitin-activating enzyme › Catalytic cysteine domain in ubiquitin-activating enzyme › Catalytic cysteine domain in ubiquitin-activating enzyme | 0.69 | 60.0 | 5.09e-01 | 100.0% | 95.8% |
| 3946046 | 101.1.2.52 ↗ | alpha arrays › HTH › HTH › winged helix domain › KicB | 0.67 | 57.0 | 5.16e-01 | 94.5% | 74.7% |
| 4580730 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.63 | 51.0 | 5.02e-01 | 92.7% | 85.0% |
| 3888131 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.60 | 47.0 | 2.87e-01 | 87.3% | 13.2% |
| 2036593 | 109.4.1.1264 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_16 | 0.59 | 47.0 | 2.90e-01 | 89.1% | 14.3% |
| 3391605 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.56 | 45.0 | 4.35e-01 | 98.2% | 92.3% |
| 3785120 | 109.4.1.68 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Coatomer_E | 0.55 | 48.0 | 3.01e-01 | 98.2% | 82.7% |
| 4935828 | 304.41.1.1 ↗ | a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N | 0.53 | 43.0 | 3.30e-01 | 98.2% | 70.3% |
D2
medium
residues 86-163
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2h09A02 | 1.10.60.10 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Iron dependent repressor, metal binding and dimerisation domain | 0.81 | 52.0 | 6.04e-01 | 70.5% | 91.1% |
| 3triA02 | 1.10.3730.10 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › ProC C-terminal domain-like | 0.74 | 51.0 | 4.58e-01 | 70.5% | 72.8% |
| 1yz6A02 | 1.10.150.190 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 | 0.72 | 51.0 | 4.93e-01 | 74.4% | 95.4% |
| 3dfuA02 | 1.10.1040.40 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › | 0.71 | 54.0 | 4.98e-01 | 80.8% | 65.7% |
| 2x4hA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.70 | 55.0 | 4.61e-01 | 83.3% | 72.9% |
| 3uoeA01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.69 | 47.0 | 4.54e-01 | 70.5% | 69.0% |
| 1nxuA01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.64 | 45.0 | 4.53e-01 | 73.1% | 74.7% |
| 3um7A03 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 46.0 | 4.24e-01 | 78.2% | 67.0% |
| 7w5lA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.63 | 46.0 | 3.26e-01 | 78.2% | 60.2% |
| 2dzlA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.63 | 43.0 | 4.64e-01 | 89.7% | 84.8% |
| 4jndA01 | 1.10.1740.220 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › | 0.61 | 47.0 | 3.92e-01 | 80.8% | 64.6% |
| 6xzqA01 | 3.40.91.90 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain | 0.61 | 42.0 | 3.37e-01 | 73.1% | 48.8% |
| 4yosA02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.61 | 48.0 | 3.85e-01 | 87.2% | 79.4% |
| 1euhA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.59 | 44.0 | 3.02e-01 | 78.2% | 66.1% |
| 3pqaB01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.59 | 43.0 | 3.01e-01 | 78.2% | 71.0% |
| 1c9bA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.59 | 42.0 | 3.91e-01 | 74.4% | 86.6% |
| 3ivpD01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.57 | 40.0 | 4.07e-01 | 71.8% | 86.7% |
| 2f2cA02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.55 | 37.0 | 3.41e-01 | 70.5% | 84.0% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1663170 | 183.1.1.1 ↗ | alpha duplicates or obligate multimers › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain › Fe_dep_repr_C | 0.81 | 52.0 | 6.04e-01 | 70.5% | 91.1% |
| 4935458 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.80 | 55.0 | 5.09e-01 | 70.5% | 76.8% |
| 4987757 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.79 | 60.0 | 5.36e-01 | 78.2% | 76.9% |
| 5057501 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.79 | 58.0 | 5.25e-01 | 75.6% | 77.0% |
| 4938196 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.79 | 54.0 | 4.79e-01 | 70.5% | 69.5% |
| 3988949 | 4070.1.1.2 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50 | 0.76 | 54.0 | 4.08e-01 | 74.4% | 81.1% |
| 4935125 | 102.3.1.1 ↗ | alpha arrays › HhH/H2TH › eIF2alpha middle domain › eIF2alpha middle domain › EIF_2_alpha | 0.75 | 52.0 | 5.13e-01 | 73.1% | 94.1% |
| 4990523 | 129.1.1.15 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › P5CR_dimer | 0.72 | 53.0 | 4.94e-01 | 76.9% | 78.9% |
| 3952706 | 101.1.4.0 ↗ | alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like | 0.71 | 53.0 | 5.39e-01 | 78.2% | 98.7% |
| 3297516 | 4953.1.1.4 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ASL_C2 | 0.70 | 49.0 | 4.75e-01 | 71.8% | 81.2% |
| 3363158 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.70 | 54.0 | 5.17e-01 | 82.1% | 97.8% |
| 4133648 | 4953.1.1.4 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ASL_C2 | 0.67 | 47.0 | 4.62e-01 | 73.1% | 78.8% |
| 3387001 | 4953.1.1.2 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ADSL_C | 0.67 | 47.0 | 4.40e-01 | 73.1% | 88.4% |
| 4980419 | 4953.1.1.2 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ADSL_C | 0.66 | 47.0 | 4.59e-01 | 74.4% | 76.5% |
| 4597106 | 4953.1.1.2 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ADSL_C | 0.65 | 46.0 | 4.47e-01 | 73.1% | 80.0% |
| 4959745 | 5073.1.2.9 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain › Cation_ATPase_C | 0.64 | 53.0 | 3.40e-01 | 97.4% | 47.9% |
| 4987541 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.57 | 43.0 | 3.86e-01 | 80.8% | 83.6% |
| 4989894 | 131.1.1.3 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD | 0.56 | 40.0 | 2.88e-01 | 73.1% | 39.5% |
| 3278083 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.51 | 38.0 | 2.74e-01 | 78.2% | 45.3% |
| 3974098 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.50 | 42.0 | 4.34e-01 | 94.9% | 96.0% |
D3
medium
residues 202-239_316-417
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2a6qA01 | 3.40.1620.10 | Alpha Beta › 3-Layer(aba) Sandwich › YefM-like fold › YefM-like domain | 0.66 | 23.0 | 3.94e-01 | 75.7% | 100.0% |
| 2gjwC01 | 3.40.1350.150 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.64 | 32.0 | 3.25e-01 | 79.3% | 46.4% |
| 3ajvC02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.60 | 33.0 | 3.98e-01 | 77.9% | 81.3% |
| 2ef7A00 | 3.10.580.10 | Alpha Beta › Roll › CBS-domain › CBS-domain | 0.59 | 29.0 | 3.10e-01 | 100.0% | 51.6% |
| 1a79A01 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.57 | 34.0 | 3.94e-01 | 79.3% | 83.0% |
| 1pbjA00 | 3.10.580.10 | Alpha Beta › Roll › CBS-domain › CBS-domain | 0.56 | 29.0 | 3.10e-01 | 84.3% | 56.3% |
| 1vr9A01 | 3.90.1280.20 | Alpha Beta › Alpha-Beta Complex › CBS domain Like › | 0.54 | 22.0 | 3.08e-01 | 73.6% | 76.6% |
| 1xkfB00 | 3.10.580.10 | Alpha Beta › Roll › CBS-domain › CBS-domain | 0.54 | 29.0 | 3.07e-01 | 100.0% | 56.1% |
| 4cooA03 | 3.10.580.10 | Alpha Beta › Roll › CBS-domain › CBS-domain | 0.54 | 29.0 | 2.93e-01 | 82.9% | 51.8% |
| 5aweA01 | 3.10.580.10 | Alpha Beta › Roll › CBS-domain › CBS-domain | 0.53 | 29.0 | 3.10e-01 | 83.6% | 60.3% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3290063 | 282.1.1.1 ↗ | a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS | 0.59 | 30.0 | 3.21e-01 | 99.3% | 53.6% |
| 5027502 | 282.1.1.1 ↗ | a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS | 0.56 | 30.0 | 3.11e-01 | 99.3% | 53.8% |
| 4982924 | 282.1.1.1 ↗ | a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS | 0.55 | 29.0 | 2.92e-01 | 99.3% | 46.9% |
| 4943700 | 282.1.1.1 ↗ | a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS | 0.55 | 29.0 | 2.98e-01 | 99.3% | 51.1% |
| 3497199 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.53 | 40.0 | 3.06e-01 | 79.3% | 90.6% |
| 5078586 | 869.1.1.1 ↗ | a+b complex topology › Methenyltetrahydromethanopterin cyclohydrolase › Methenyltetrahydromethanopterin cyclohydrolase › Methenyltetrahydromethanopterin cyclohydrolase › MCH | 0.53 | 37.0 | 2.85e-01 | 70.0% | 70.8% |
| 4986158 | 282.1.1.1 ↗ | a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS | 0.53 | 27.0 | 2.94e-01 | 99.3% | 54.2% |
D4
medium
residues 240-315
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 63.0 | 5.34e-01 | 100.0% | 93.4% |
| 2ewfA02 | 1.20.1270.310 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 47.0 | 4.66e-01 | 77.6% | 86.4% |
| 2pmrA00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.64 | 48.0 | 4.90e-01 | 81.6% | 98.7% |
| 2olpA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.63 | 48.0 | 3.89e-01 | 84.2% | 88.7% |
| 2b5dX02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.63 | 46.0 | 4.02e-01 | 77.6% | 73.7% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 54.0 | 4.37e-01 | 100.0% | 78.1% |
| 4z7xB00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.62 | 54.0 | 4.00e-01 | 98.7% | 37.5% |
| 4hfvA01 | 1.20.1440.330 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.61 | 49.0 | 4.37e-01 | 92.1% | 88.0% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 44.0 | 4.47e-01 | 77.6% | 92.0% |
| 3fyaB00 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.61 | 53.0 | 5.36e-01 | 98.7% | 97.4% |
| 2v8pA01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.58 | 47.0 | 3.82e-01 | 92.1% | 56.1% |
| 7dniB01 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.58 | 45.0 | 4.33e-01 | 96.1% | 74.2% |
| 7dniC02 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.58 | 45.0 | 4.21e-01 | 90.8% | 68.1% |
| 1v07A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 49.0 | 4.42e-01 | 100.0% | 88.2% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.56 | 35.0 | 3.66e-01 | 100.0% | 69.1% |
| 1v4gA01 | 6.10.140.800 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 32.0 | 3.38e-01 | 100.0% | 59.4% |
| 2psmA00 | 1.20.1250.70 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 | 0.55 | 45.0 | 4.00e-01 | 93.4% | 95.7% |
| 2p35A02 | 1.10.150.290 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › S-adenosyl-L-methionine-dependent methyltransferases | 0.54 | 44.0 | 4.60e-01 | 100.0% | 100.0% |
| 1b0bA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 47.0 | 3.88e-01 | 100.0% | 72.3% |
| 7r0kA01 | 1.20.1060.10 | Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 | 0.53 | 46.0 | 4.15e-01 | 100.0% | 94.4% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.53 | 39.0 | 3.92e-01 | 78.9% | 91.1% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.53 | 37.0 | 3.58e-01 | 75.0% | 93.4% |
| 1lqsL01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 45.0 | 4.19e-01 | 100.0% | 87.0% |
| 4b4yA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 45.0 | 3.73e-01 | 100.0% | 65.1% |
| 6h7bA01 | 1.10.1900.10 | Mainly Alpha › Orthogonal Bundle › c-terminal domain of poly(a) binding protein › c-terminal domain of poly(a) binding protein | 0.50 | 34.0 | 3.51e-01 | 72.4% | 75.7% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5060143 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.72 | 52.0 | 5.15e-01 | 76.3% | 80.0% |
| 5067410 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.70 | 52.0 | 4.87e-01 | 77.6% | 90.0% |
| 4457750 | 3567.1.1.112 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › AI-2E_transport | 0.70 | 62.0 | 5.48e-01 | 100.0% | 71.8% |
| 5036728 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.70 | 51.0 | 5.31e-01 | 77.6% | 91.4% |
| 3961048 | 4953.1.1.7 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › AI-2E_transport | 0.69 | 61.0 | 5.78e-01 | 100.0% | 85.6% |
| 4241645 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.68 | 49.0 | 4.70e-01 | 77.6% | 93.3% |
| 3670047 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.65 | 47.0 | 4.65e-01 | 76.3% | 96.2% |
| 5059135 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.65 | 47.0 | 4.84e-01 | 76.3% | 94.3% |
| 4998043 | 633.29.1.13 ↗ | alpha bundles › Bromodomain-like › Putative uncharacterized protein PAV1-137 › Putative uncharacterized protein PAV1-137 › DUF2096_N | 0.65 | 55.0 | 5.09e-01 | 96.1% | 95.0% |
| 5060141 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.65 | 47.0 | 4.93e-01 | 77.6% | 94.2% |
| 3999659 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.61 | 43.0 | 4.40e-01 | 75.0% | 92.0% |
| 5016561 | 3003.1.1.0 ↗ | a+b complex topology › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) | 0.61 | 38.0 | 3.67e-01 | 96.1% | 56.5% |
| 3595102 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.61 | 45.0 | 4.41e-01 | 80.3% | 97.6% |
| 4015095 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.58 | 50.0 | 4.13e-01 | 100.0% | 71.0% |
| 4959564 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.58 | 42.0 | 3.00e-01 | 78.9% | 37.5% |
| 5036629 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.57 | 39.0 | 3.94e-01 | 72.4% | 92.5% |
| 4930280 | 3930.1.1.3 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical | 0.57 | 49.0 | 4.24e-01 | 100.0% | 98.4% |
| 3425013 | 101.1.1.65 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4 | 0.57 | 33.0 | 2.69e-01 | 100.0% | 29.3% |
| 3725482 | 601.16.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase | 0.55 | 38.0 | 3.36e-01 | 73.7% | 80.8% |
| 3989453 | 162.1.1.1 ↗ | alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PRD | 0.54 | 47.0 | 4.22e-01 | 100.0% | 70.0% |
| 3686452 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.53 | 36.0 | 3.25e-01 | 71.1% | 86.1% |
| 4170026 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.52 | 38.0 | 3.21e-01 | 77.6% | 48.6% |
| 3631285 | 7515.1.1.6 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Phosphodiest | 0.51 | 44.0 | 2.78e-01 | 100.0% | 85.1% |
| 3215424 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 39.0 | 2.78e-01 | 81.6% | 30.7% |