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IMGVR_UViG_3300038313_000213-3300038313-Ga0134846_000572_31974_33209
Arc-VirIMGVR_UViG_3300038313_000213-3300038313-Ga0134846_000572_31974_33209
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 13-125
Domain cluster:
rep: SR-VP_2-4_scaffold_141_2548329_prodigal-single.1__X__X__00081__D24-126
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2cqnA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.73 | 47.0 | 5.56e-01 | 85.0% | 94.8% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.67 | 39.0 | 3.81e-01 | 100.0% | 52.8% |
| 5k29A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.64 | 43.0 | 4.65e-01 | 71.7% | 80.4% |
| 7s03A01 | 1.10.10.1450 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.63 | 29.0 | 4.23e-01 | 76.1% | 100.0% |
| 4etsA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 37.0 | 4.16e-01 | 82.3% | 77.0% |
| 2xseA00 | 1.20.120.1440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › JBP1, DNA-binding domain | 0.60 | 43.0 | 3.83e-01 | 73.5% | 62.9% |
| 3rr1A01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.59 | 44.0 | 4.09e-01 | 93.8% | 63.5% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 41.0 | 4.36e-01 | 73.5% | 93.1% |
| 8cdaC01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.57 | 43.0 | 4.25e-01 | 96.5% | 76.1% |
| 2dg7A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 47.0 | 3.99e-01 | 90.3% | 59.7% |
| 4jqfA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 36.0 | 4.28e-01 | 82.3% | 100.0% |
| 3llkA02 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.55 | 41.0 | 3.81e-01 | 89.4% | 61.5% |
| 7bgi701 | 1.10.3460.10 | Mainly Alpha › Orthogonal Bundle › Chlorophyll a-b binding protein › Chlorophyll a/b binding protein domain | 0.53 | 43.0 | 3.76e-01 | 85.0% | 98.8% |
| 4rflA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.52 | 41.0 | 3.41e-01 | 84.1% | 84.9% |
| 2xl4A00 | 1.20.120.1420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain | 0.52 | 45.0 | 4.18e-01 | 98.2% | 95.9% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.51 | 44.0 | 4.12e-01 | 96.5% | 87.7% |
| 1f1mA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.51 | 45.0 | 4.03e-01 | 98.2% | 96.3% |
| 6yxr101 | 1.10.3460.10 | Mainly Alpha › Orthogonal Bundle › Chlorophyll a-b binding protein › Chlorophyll a/b binding protein domain | 0.50 | 35.0 | 3.04e-01 | 70.8% | 72.2% |
ECOD (44)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4945101 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.97 | 86.0 | 7.12e-01 | 100.0% | 57.2% |
| 5051051 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.97 | 87.0 | 7.35e-01 | 100.0% | 61.2% |
| 4946450 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.97 | 74.0 | 8.41e-01 | 86.7% | 100.0% |
| 4945073 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.97 | 75.0 | 8.47e-01 | 88.5% | 100.0% |
| 5026427 | 7000.1.1.0 ↗ | alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS | 0.91 | 75.0 | 8.19e-01 | 87.6% | 100.0% |
| 4963511 | 2.21.1.0 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) | 0.88 | 76.0 | 6.27e-01 | 100.0% | 56.1% |
| 4999064 | 7000.1.1.1 ↗ | alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › HTH_OrfB_IS605 | 0.84 | 65.0 | 7.21e-01 | 92.0% | 100.0% |
| 4975282 | 545.1.2.0 ↗ | alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain | 0.84 | 58.0 | 6.84e-01 | 87.6% | 100.0% |
| 4999336 | 7000.1.1.0 ↗ | alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS | 0.83 | 61.0 | 7.00e-01 | 88.5% | 100.0% |
| 4935180 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.82 | 69.0 | 7.37e-01 | 100.0% | 99.0% |
| 3439489 | 101.1.17.2 ↗ | alpha arrays › HTH › HTH › FF domain › FF | 0.81 | 50.0 | 5.57e-01 | 72.6% | 77.8% |
| 3537310 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.78 | 45.0 | 5.82e-01 | 70.8% | 100.0% |
| 5004767 | 2.21.1.3 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605 | 0.78 | 66.0 | 5.36e-01 | 100.0% | 50.2% |
| 3225117 | 101.1.17.2 ↗ | alpha arrays › HTH › HTH › FF domain › FF | 0.77 | 45.0 | 5.73e-01 | 72.6% | 100.0% |
| 3536102 | 101.1.17.2 ↗ | alpha arrays › HTH › HTH › FF domain › FF | 0.77 | 45.0 | 5.72e-01 | 72.6% | 100.0% |
| 3955159 | 2.21.1.3 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605 | 0.76 | 69.0 | 5.66e-01 | 100.0% | 84.2% |
| 5044635 | 2.21.1.3 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605 | 0.74 | 68.0 | 5.83e-01 | 100.0% | 86.9% |
| 4019411 | 101.21.1.0 ↗ | alpha arrays › HTH › HTH domain in DNA topoisomerase IV alpha subunit › HTH domain in DNA topoisomerase IV alpha subunit | 0.73 | 46.0 | 5.48e-01 | 70.8% | 96.0% |
| 5002913 | 2.21.1.3 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605 | 0.71 | 65.0 | 5.68e-01 | 100.0% | 84.1% |
| 5021605 | 2.21.1.3 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605 | 0.68 | 62.0 | 5.47e-01 | 100.0% | 84.8% |
| 3416051 | 101.21.1.2 ↗ | alpha arrays › HTH › HTH domain in DNA topoisomerase IV alpha subunit › HTH domain in DNA topoisomerase IV alpha subunit › Nucleolin_bd | 0.67 | 38.0 | 4.76e-01 | 84.1% | 96.9% |
| 3787585 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.65 | 41.0 | 4.28e-01 | 100.0% | 68.6% |
| 4962879 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.65 | 63.0 | 5.38e-01 | 100.0% | 82.2% |
| 3889971 | 109.4.1.1643 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RSLD_CPSF6 | 0.61 | 40.0 | 4.08e-01 | 72.6% | 67.3% |
| 4278019 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.60 | 50.0 | 4.50e-01 | 92.0% | 78.1% |
| 5000306 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 41.0 | 4.67e-01 | 88.5% | 97.6% |
| 3650596 | 603.1.1.61 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Mito_carr | 0.58 | 41.0 | 4.23e-01 | 73.5% | 100.0% |
| 3241365 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.58 | 42.0 | 3.75e-01 | 74.3% | 86.9% |
| 3270728 | 5001.1.1.81 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › THH1_TOM1-3_dom | 0.58 | 44.0 | 3.35e-01 | 82.3% | 80.7% |
| 4954375 | 601.7.1.20 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Abi_C | 0.58 | 42.0 | 4.14e-01 | 75.2% | 76.7% |
| 3773905 | 604.3.1.33 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › RSLD_CPSF6 | 0.56 | 36.0 | 4.31e-01 | 74.3% | 97.3% |
| 3717247 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.56 | 39.0 | 3.16e-01 | 70.8% | 56.4% |
| 3173920 | 2003.1.2.24 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 | 0.56 | 48.0 | 3.46e-01 | 95.6% | 95.0% |
| 3402106 | 101.1.1.112 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › MADF_DNA_bdg | 0.56 | 44.0 | 4.68e-01 | 88.5% | 96.0% |
| 3697040 | 109.26.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nucleoporin_C | 0.55 | 40.0 | 2.81e-01 | 77.0% | 30.9% |
| 3499672 | 1203.1.2.13 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › Ribophorin_II | 0.55 | 41.0 | 3.82e-01 | 81.4% | 75.3% |
| 3382499 | 3755.3.1.308 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF629 | 0.54 | 49.0 | 4.24e-01 | 99.1% | 66.3% |
| 3695390 | 101.1.17.18 ↗ | alpha arrays › HTH › HTH › FF domain › FF_PRPF40A | 0.54 | 37.0 | 4.24e-01 | 70.8% | 98.8% |
| 3685493 | 605.2.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › DUF7785 | 0.54 | 36.0 | 4.14e-01 | 84.1% | 91.8% |
| 3188738 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.52 | 43.0 | 3.30e-01 | 93.8% | 76.3% |
| 3815707 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.51 | 43.0 | 4.31e-01 | 91.2% | 91.3% |
| 4977923 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.51 | 37.0 | 3.33e-01 | 76.1% | 83.1% |
| 3719915 | 109.4.1.72 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps16_C | 0.51 | 38.0 | 2.91e-01 | 78.8% | 35.3% |
| 4857837 | 1016.1.1.2 ↗ | alpha arrays › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Caprin-1_dimer | 0.50 | 34.0 | 3.42e-01 | 85.0% | 66.9% |
D2
high
residues 127-180
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2cxcA02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.67 | 44.0 | 4.07e-01 | 92.6% | 52.2% |
| 3q6kA00 | 2.120.10.30 | Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain | 0.66 | 54.0 | 3.34e-01 | 98.1% | 40.0% |
| 2v8qB00 | 6.20.250.60 | Special › Other non-globular › Double Stranded RNA Binding Domain › | 0.62 | 36.0 | 3.23e-01 | 96.3% | 41.1% |
| 2qrdB01 | 2.20.25.290 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.60 | 35.0 | 3.95e-01 | 96.3% | 81.1% |
| 3bt7A02 | 2.40.50.1070 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.59 | 50.0 | 3.80e-01 | 100.0% | 54.5% |
| 1q8iA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.55 | 35.0 | 2.30e-01 | 96.3% | 16.3% |
| 3o27B00 | 2.10.260.10 | Mainly Beta › Ribbon › Pemi-like Protein 1; Chain: D › | 0.54 | 38.0 | 3.83e-01 | 75.9% | 77.2% |
| 2i4kA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.50 | 37.0 | 2.93e-01 | 83.3% | 96.9% |
| 2dpyA00 | 3.40.50.12240 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.50 | 35.0 | 2.19e-01 | 79.6% | 25.4% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5051051 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.94 | 88.0 | 5.96e-01 | 100.0% | 31.8% |
| 3935327 | 11.1.1.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set | 0.68 | 32.0 | 3.31e-01 | 96.3% | 46.0% |
| 3782385 | 5.1.4.78 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › TFIIIC_delta | 0.62 | 50.0 | 3.01e-01 | 98.1% | 25.1% |
| 5032176 | 1.1.3.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › AbrB › MazE_antitoxin | 0.58 | 40.0 | 3.89e-01 | 70.4% | 81.7% |
| 3675128 | 304.9.1.20 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_8 | 0.57 | 40.0 | 3.70e-01 | 72.2% | 60.0% |
| 4003000 | 5.1.3.137 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1, Kelch_2, Kelch_KLHDC2_KLHL20_DRC7 | 0.54 | 43.0 | 3.13e-01 | 96.3% | 85.9% |
| 5054267 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.52 | 41.0 | 2.83e-01 | 98.1% | 46.9% |
| 3193754 | 2.1.1.87 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RPA43_OB | 0.51 | 43.0 | 3.44e-01 | 98.1% | 73.7% |
D3
medium
residues 183-215_307-391_399-408
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07282.19 best | Cas12f1-like_TNB | 42.8 | 6.50e-11 | 56.2% | 100.0% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1x0tA02 | 6.20.50.20 | Special › Other non-globular › N-terminal domain of TfIIb › | 0.62 | 18.0 | 2.99e-01 | 93.0% | 68.9% |
| 1e3mB02 | 3.30.420.110 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › MutS, connector domain | 0.60 | 52.0 | 5.20e-01 | 92.2% | 100.0% |
| 1ewqA02 | 3.30.420.110 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › MutS, connector domain | 0.55 | 47.0 | 4.89e-01 | 93.0% | 99.2% |
| 7o06C01 | 3.30.1470.10 | Alpha Beta › 2-Layer Sandwich › Photosystem 1 Reaction Centre Subunit Ii; Chain: D; › Photosystem I PsaD, reaction center subunit II | 0.52 | 30.0 | 3.49e-01 | 80.5% | 79.1% |
| 3zm6A02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.52 | 43.0 | 3.71e-01 | 93.8% | 94.6% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5072202 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.98 | 92.0 | 7.74e-01 | 95.3% | 100.0% |
| 5075582 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.97 | 94.0 | 7.37e-01 | 98.4% | 100.0% |
| 4933534 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.84 | 77.0 | 6.40e-01 | 95.3% | 98.5% |
| 4946534 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.83 | 73.0 | 5.60e-01 | 91.4% | 99.2% |
| 5055179 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.82 | 72.0 | 5.99e-01 | 92.2% | 97.1% |
| 5004517 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.82 | 71.0 | 5.84e-01 | 89.8% | 95.7% |
| 4933788 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.81 | 72.0 | 5.94e-01 | 92.2% | 98.1% |
| 5005258 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.81 | 70.0 | 5.85e-01 | 89.8% | 98.0% |
| 4941648 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.81 | 70.0 | 5.94e-01 | 90.6% | 97.9% |
| 4961801 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.80 | 68.0 | 5.68e-01 | 88.3% | 98.0% |
| 4994780 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.80 | 72.0 | 5.94e-01 | 94.5% | 100.0% |
| 4979039 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.80 | 70.0 | 5.82e-01 | 91.4% | 100.0% |
| 4979556 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.80 | 68.0 | 5.64e-01 | 89.8% | 96.7% |
| 4979830 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.80 | 72.0 | 6.36e-01 | 92.2% | 100.0% |
| 5023627 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.80 | 73.0 | 6.01e-01 | 96.9% | 97.7% |
| 4943798 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.79 | 72.0 | 5.91e-01 | 96.9% | 96.8% |
| 5003640 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.79 | 69.0 | 5.81e-01 | 91.4% | 100.0% |
| 4934194 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.79 | 70.0 | 5.88e-01 | 93.0% | 100.0% |
| 5076085 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.78 | 68.0 | 5.62e-01 | 91.4% | 95.2% |
| 4934385 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.78 | 64.0 | 5.46e-01 | 85.2% | 96.3% |
| 4977784 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.78 | 69.0 | 5.55e-01 | 94.5% | 100.0% |
| 4979486 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.77 | 65.0 | 5.71e-01 | 86.7% | 96.6% |
| 3955489 | 2484.1.1.211 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605, Cas12f1-like_TNB | 0.76 | 63.0 | 5.30e-01 | 88.3% | 100.0% |
| 4173456 | 2484.1.1.211 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605, Cas12f1-like_TNB | 0.75 | 61.0 | 5.25e-01 | 85.9% | 99.5% |
| 4976214 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.72 | 61.0 | 5.21e-01 | 89.8% | 100.0% |
| 5051266 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.68 | 63.0 | 5.17e-01 | 99.2% | 99.6% |
| 3596564 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.65 | 53.0 | 3.74e-01 | 88.3% | 93.6% |
| 4943069 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.64 | 55.0 | 5.31e-01 | 89.8% | 82.9% |
| 4934216 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.62 | 49.0 | 4.89e-01 | 91.4% | 80.0% |
| 5064569 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.59 | 51.0 | 4.51e-01 | 90.6% | 100.0% |
| 4965851 | 4100.1.1.9 ↗ | a+b duplicates or obligate multimers › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like › DUF7387 | 0.57 | 19.0 | 2.83e-01 | 96.1% | 65.5% |
| 4406771 | 2484.1.1.48 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II | 0.53 | 47.0 | 4.73e-01 | 98.4% | 98.5% |
| 146960 | 3182.2.1.1 ↗ | mixed a+b and a/b › a+b domains in a putative cell invasion protein › second a+b domain in a putative cell invasion protein › second a+b domain in a putative cell invasion protein › MACPF_D3 | 0.51 | 28.0 | 3.58e-01 | 95.3% | 100.0% |
| 3307519 | 4100.1.1.0 ↗ | a+b duplicates or obligate multimers › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like | 0.50 | 28.0 | 3.47e-01 | 85.9% | 94.3% |
D4
medium
residues 216-306
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01385.26 best | OrfB_IS605 | 46.7 | 4.90e-12 | 83.5% | 62.5% |
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1yc9A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.74 | 54.0 | 3.66e-01 | 76.9% | 23.2% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 54.0 | 5.00e-01 | 82.4% | 62.3% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 48.0 | 5.20e-01 | 70.3% | 96.1% |
| 4r42A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.64 | 47.0 | 3.70e-01 | 76.9% | 73.3% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.63 | 50.0 | 4.60e-01 | 84.6% | 65.3% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 43.0 | 4.49e-01 | 71.4% | 83.1% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 45.0 | 4.53e-01 | 89.0% | 74.7% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.62 | 49.0 | 4.85e-01 | 100.0% | 80.4% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.61 | 40.0 | 4.34e-01 | 75.8% | 80.3% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 47.0 | 4.58e-01 | 100.0% | 75.5% |
| 1b04A03 | 1.10.287.610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.60 | 38.0 | 4.52e-01 | 100.0% | 95.2% |
| 7xxiA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 53.0 | 3.75e-01 | 100.0% | 85.2% |
| 4ofzA01 | 1.20.58.1800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 40.0 | 3.69e-01 | 100.0% | 57.5% |
| 2q0tB01 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.56 | 39.0 | 2.85e-01 | 70.3% | 74.0% |
| 1hciA04 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 45.0 | 4.24e-01 | 100.0% | 71.9% |
| 3no6A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.55 | 47.0 | 3.50e-01 | 94.5% | 71.5% |
| 1l3eB00 | 1.20.1020.10 | Mainly Alpha › Up-down Bundle › CREB-binding Protein; Chain A › TAZ domain | 0.55 | 40.0 | 3.87e-01 | 75.8% | 70.3% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 46.0 | 4.47e-01 | 100.0% | 84.6% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4943798 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.89 | 83.0 | 6.08e-01 | 100.0% | 42.3% |
| 4995140 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.87 | 80.0 | 6.69e-01 | 100.0% | 61.4% |
| 4934194 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.86 | 82.0 | 6.12e-01 | 100.0% | 52.5% |
| 4934281 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.86 | 82.0 | 6.82e-01 | 100.0% | 63.2% |
| 3699443 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.83 | 57.0 | 5.21e-01 | 70.3% | 58.3% |
| 3596488 | 3737.1.1.0 ↗ | alpha duplicates or obligate multimers › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats | 0.82 | 56.0 | 5.00e-01 | 70.3% | 53.6% |
| 4013947 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.82 | 55.0 | 3.94e-01 | 70.3% | 26.2% |
| 3298709 | 605.1.1.141 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Rx_N | 0.76 | 52.0 | 4.65e-01 | 70.3% | 53.6% |
| 3988454 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 49.0 | 5.58e-01 | 70.3% | 87.1% |
| 3611632 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.73 | 50.0 | 4.88e-01 | 70.3% | 81.0% |
| 3686172 | 109.4.1.496 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec5 | 0.73 | 55.0 | 3.30e-01 | 80.2% | 25.5% |
| 3654609 | 109.4.1.1260 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, PPR_long | 0.73 | 35.0 | 2.80e-01 | 94.5% | 24.0% |
| 5002748 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.72 | 47.0 | 5.12e-01 | 70.3% | 80.0% |
| 4619538 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.72 | 49.0 | 4.51e-01 | 70.3% | 54.8% |
| 5035232 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.72 | 47.0 | 5.24e-01 | 73.6% | 85.7% |
| 4977416 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.72 | 51.0 | 3.74e-01 | 74.7% | 87.0% |
| 3176191 | 3922.1.1.242 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DDT | 0.70 | 48.0 | 3.38e-01 | 70.3% | 23.6% |
| 4177674 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.70 | 47.0 | 4.47e-01 | 70.3% | 57.3% |
| 4493879 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.69 | 47.0 | 4.43e-01 | 71.4% | 57.3% |
| 3856684 | 5001.1.1.43 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › V1R | 0.68 | 48.0 | 3.32e-01 | 73.6% | 24.2% |
| 3714155 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 50.0 | 4.98e-01 | 100.0% | 73.7% |
| 3840952 | 601.19.1.39 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › LIN9_C | 0.68 | 45.0 | 4.94e-01 | 70.3% | 84.0% |
| 4043561 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.66 | 44.0 | 4.15e-01 | 70.3% | 56.4% |
| 5050359 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.66 | 45.0 | 5.08e-01 | 75.8% | 92.9% |
| 3754639 | 150.5.1.106 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › LIN9_C | 0.65 | 44.0 | 4.57e-01 | 71.4% | 74.1% |
| 3473769 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.63 | 43.0 | 3.14e-01 | 70.3% | 32.2% |
| 3477418 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.63 | 46.0 | 4.55e-01 | 76.9% | 80.0% |
| 3872677 | 5089.1.1.12 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › BRINP | 0.63 | 57.0 | 5.18e-01 | 95.6% | 87.0% |
| 4476660 | 192.8.1.478 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › BAG6 | 0.62 | 43.0 | 3.87e-01 | 71.4% | 57.6% |
| 3349382 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.61 | 53.0 | 4.60e-01 | 96.7% | 77.9% |
| 3240453 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 49.0 | 4.77e-01 | 100.0% | 80.0% |
| 4228184 | 192.4.1.1 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 | 0.58 | 42.0 | 4.00e-01 | 87.9% | 64.8% |
| 4107135 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.56 | 40.0 | 3.88e-01 | 75.8% | 68.0% |
| 4021907 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.55 | 48.0 | 4.02e-01 | 100.0% | 55.0% |
| 3728803 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 49.0 | 4.06e-01 | 100.0% | 75.6% |
| 4015520 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 48.0 | 3.97e-01 | 100.0% | 75.2% |
| 3200734 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.54 | 48.0 | 3.97e-01 | 100.0% | 73.9% |
| 3306934 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.54 | 41.0 | 3.82e-01 | 79.1% | 95.5% |
| 3899274 | 109.4.1.108 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CTNNBL | 0.50 | 42.0 | 2.64e-01 | 93.4% | 29.0% |