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IMGVR_UViG_3300038326_000206-3300038326-Ga0427875_002333_5894_6388
Arc-VirIMGVR_UViG_3300038326_000206-3300038326-Ga0427875_002333_5894_6388
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 20-129
Domain cluster:
rep: NC_004735.1__NP_835607.1__Rm378p020__00020__D38-141
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1or7B01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.83 | 63.0 | 6.83e-01 | 88.2% | 93.6% |
| 4nqwA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.80 | 59.0 | 6.57e-01 | 84.5% | 100.0% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.79 | 32.0 | 3.66e-01 | 77.3% | 51.2% |
| 4cxfA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.76 | 57.0 | 6.33e-01 | 90.0% | 100.0% |
| 6ldiF01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.74 | 54.0 | 5.74e-01 | 84.5% | 86.5% |
| 1rp3A01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.74 | 54.0 | 6.09e-01 | 76.4% | 100.0% |
| 3kkcA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 49.0 | 4.26e-01 | 80.0% | 64.7% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.63 | 44.0 | 4.95e-01 | 77.3% | 97.5% |
| 2qksA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 39.0 | 3.98e-01 | 98.2% | 66.0% |
| 2iu5B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 51.0 | 4.34e-01 | 90.0% | 68.4% |
| 4gx0A01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 40.0 | 4.18e-01 | 98.2% | 72.8% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.60 | 41.0 | 4.43e-01 | 70.0% | 86.4% |
| 3n3dB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.58 | 45.0 | 3.33e-01 | 85.5% | 78.9% |
| 3lwjA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 46.0 | 3.92e-01 | 90.0% | 72.0% |
| 4h33A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 34.0 | 3.73e-01 | 94.5% | 72.5% |
| 2w0gA00 | 1.20.58.610 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain | 0.57 | 42.0 | 3.98e-01 | 76.4% | 85.3% |
| 2j0wA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.56 | 42.0 | 4.46e-01 | 80.0% | 93.5% |
| 1zk8B02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 43.0 | 4.07e-01 | 83.6% | 87.1% |
| 1wtyA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.54 | 40.0 | 3.98e-01 | 77.3% | 99.1% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 37.0 | 3.80e-01 | 70.0% | 93.5% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 35.0 | 3.90e-01 | 80.0% | 82.8% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 38.0 | 3.62e-01 | 73.6% | 73.9% |
| 2eh3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 41.0 | 4.06e-01 | 83.6% | 95.9% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.53 | 40.0 | 3.89e-01 | 78.2% | 83.2% |
| 2raeA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 40.0 | 3.80e-01 | 82.7% | 65.7% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.53 | 37.0 | 3.62e-01 | 73.6% | 68.0% |
| 2np5D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 42.0 | 3.74e-01 | 87.3% | 96.2% |
| 2iaiA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 41.0 | 3.90e-01 | 88.2% | 98.5% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.52 | 42.0 | 3.46e-01 | 90.9% | 93.5% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3574561 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.93 | 88.0 | 7.92e-01 | 97.3% | 84.3% |
| 4508577 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.83 | 71.0 | 6.92e-01 | 97.3% | 83.3% |
| 3942242 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.79 | 34.0 | 3.14e-01 | 100.0% | 32.1% |
| 4349095 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.78 | 59.0 | 5.85e-01 | 85.5% | 75.7% |
| 3971939 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.76 | 53.0 | 6.00e-01 | 74.5% | 94.1% |
| 3284058 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.75 | 55.0 | 6.08e-01 | 90.9% | 98.8% |
| 61904 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.73 | 55.0 | 6.10e-01 | 78.2% | 100.0% |
| 4032673 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.73 | 67.0 | 5.10e-01 | 100.0% | 70.2% |
| None | — | 0.73 | 67.0 | 5.28e-01 | 100.0% | 52.7% | |
| 4258677 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.73 | 67.0 | 5.24e-01 | 100.0% | 51.6% |
| 4359328 | 142.1.1.44 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › GerPC | 0.73 | 52.0 | 5.46e-01 | 74.5% | 100.0% |
| 4233279 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.70 | 63.0 | 4.87e-01 | 98.2% | 58.7% |
| 4976283 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.65 | 42.0 | 4.21e-01 | 98.2% | 63.5% |
| 4506271 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 45.0 | 4.15e-01 | 78.2% | 77.9% |
| 3493057 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.61 | 44.0 | 3.18e-01 | 75.5% | 37.1% |
| 5038663 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.60 | 43.0 | 3.18e-01 | 98.2% | 30.0% |
| 4995939 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.60 | 37.0 | 3.86e-01 | 79.1% | 65.7% |
| 5023625 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.59 | 37.0 | 3.94e-01 | 80.0% | 70.0% |
| 3278203 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.59 | 47.0 | 4.39e-01 | 87.3% | 93.6% |
| 3980210 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.58 | 38.0 | 2.85e-01 | 98.2% | 27.1% |
| 3487164 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.57 | 40.0 | 2.98e-01 | 98.2% | 28.9% |
| 3410493 | 5054.1.1.1 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Lig_chan | 0.57 | 39.0 | 3.51e-01 | 99.1% | 51.3% |
| 3411996 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.56 | 38.0 | 3.48e-01 | 99.1% | 53.1% |
| 3956601 | 191.1.1.17 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_13 | 0.56 | 43.0 | 4.58e-01 | 83.6% | 100.0% |
| 3404120 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.56 | 39.0 | 3.55e-01 | 100.0% | 54.5% |
| 5006972 | 5045.1.1.3 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › V_ATPase_I | 0.55 | 41.0 | 3.15e-01 | 78.2% | 85.3% |
| 4241645 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.53 | 37.0 | 4.11e-01 | 71.8% | 100.0% |
| 3604077 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.53 | 40.0 | 3.71e-01 | 80.9% | 77.1% |
| 4789617 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.52 | 33.0 | 3.57e-01 | 92.7% | 74.5% |
| 3265711 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.51 | 43.0 | 3.87e-01 | 89.1% | 77.2% |
| 3270478 | 6155.1.1.4 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC | 0.51 | 38.0 | 3.95e-01 | 79.1% | 92.4% |
| 4978032 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.50 | 39.0 | 3.32e-01 | 95.5% | 49.7% |
D2
medium
residues 132-163
Domain cluster:
representative