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IMGVR_UViG_3300038365_000206-3300038365-Ga0134850_000025_70686_71039

Arc-Vir

IMGVR_UViG_3300038365_000206-3300038365-Ga0134850_000025_70686_71039

Identity

Kingdom:
archaea

Quality

77.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 10-65
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2bbrA02 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.75 61.0 5.07e-01 91.1% 90.0%
1wh4A01 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.73 57.0 4.84e-01 85.7% 97.9%
2ms7A00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.73 62.0 5.06e-01 94.6% 94.1%
1t3dA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.72 62.0 4.67e-01 98.2% 70.0%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.68 54.0 3.97e-01 89.3% 95.5%
1wxpA01 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.67 54.0 4.78e-01 91.1% 100.0%
2kj8A00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.65 54.0 4.39e-01 98.2% 72.9%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 52.0 3.90e-01 100.0% 84.6%
7smgD00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.59 46.0 3.54e-01 91.1% 66.2%
1sqgA01 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.57 46.0 3.65e-01 100.0% 55.3%
3cl3A02 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.56 45.0 3.97e-01 100.0% 60.2%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 39.0 3.92e-01 98.2% 77.2%
4g1tA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 47.0 3.63e-01 98.2% 61.8%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.54 42.0 4.03e-01 87.5% 94.0%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.53 43.0 3.76e-01 91.1% 66.3%
3bhgA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.52 40.0 3.33e-01 91.1% 67.0%
1z4mA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.52 36.0 2.77e-01 73.2% 49.6%
2vixA02 1.10.150.630 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.52 41.0 3.73e-01 98.2% 94.4%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.51 44.0 3.09e-01 98.2% 70.5%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.51 39.0 3.58e-01 91.1% 62.3%
3akjA02 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.50 42.0 2.94e-01 98.2% 77.1%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3775373 110.1.1.1 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › Death 0.74 65.0 5.17e-01 98.2% 87.3%
5070237 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.73 50.0 4.27e-01 71.4% 91.1%
3920796 110.1.1.1 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › Death 0.71 62.0 5.22e-01 98.2% 92.6%
3238639 509.1.1.14 ↗ alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › ANIS5_cation-bd 0.67 52.0 5.03e-01 89.3% 100.0%
4023960 2.9.1.1 ↗ beta barrels › OB-fold › RNB domain-like › RNB domain-like › RNB 0.66 55.0 3.29e-01 100.0% 12.4%
3528233 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.66 52.0 4.74e-01 87.5% 98.7%
5060430 141.1.1.1 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt 0.65 50.0 3.15e-01 87.5% 86.8%
3621979 3198.1.1.1 ↗ alpha bundles › ABA-1 repeat unit › ABA-1 repeat unit › ABA-1 repeat unit › NPA 0.63 48.0 3.91e-01 89.3% 61.7%
3234685 3065.1.1.1 ↗ alpha bundles › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › ANIS5_cation-bd 0.62 49.0 3.95e-01 92.9% 50.0%
3266910 189.1.1.2 ↗ alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP › RhoGAP 0.61 48.0 3.33e-01 87.5% 33.2%
4439341 4126.1.1.6 ↗ a/b three-layered sandwiches › beta-carbonic anhydrase-like › beta-carbonic anhydrase › beta-carbonic anhydrase › DabA 0.61 44.0 2.92e-01 100.0% 18.5%
3215990 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.60 50.0 4.63e-01 92.9% 86.3%
3349724 397.7.1.0 ↗ few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 0.60 34.0 4.15e-01 92.9% 91.4%
3233668 108.1.1.156 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › ANIS5_cation-bd 0.58 46.0 4.53e-01 92.9% 100.0%
3824434 109.4.1.1257 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 0.58 50.0 3.33e-01 94.6% 32.7%
3826293 109.4.1.1296 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long, TPR_24 0.58 51.0 3.19e-01 96.4% 22.8%
5024512 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.57 40.0 4.24e-01 78.6% 84.0%
3941821 3577.1.1.1 ↗ alpha arrays › Macrodomain Ter protein MatP › Macrodomain Ter protein MatP › Macrodomain Ter protein MatP › MatP 0.57 49.0 4.63e-01 100.0% 97.1%
4359316 610.3.1.0 ↗ alpha arrays › ERP29 C domain-like › GatB/GatE C-terminal domain › GatB/GatE C-terminal domain 0.57 39.0 2.92e-01 71.4% 27.3%
3482686 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.56 44.0 3.72e-01 83.9% 84.4%
3225129 3065.1.1.1 ↗ alpha bundles › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › ANIS5_cation-bd 0.54 46.0 3.77e-01 100.0% 52.2%
3236431 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.53 38.0 3.65e-01 76.8% 70.0%
4025194 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.53 40.0 4.04e-01 82.1% 94.5%
3507798 101.1.1.1 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.52 42.0 4.12e-01 100.0% 96.9%
3213281 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.52 46.0 2.93e-01 100.0% 78.1%
4958345 316.1.1.85 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_5 0.52 41.0 2.83e-01 98.2% 59.2%
3617253 102.1.2.12 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase › HHH,HhH-GPD,EndIII_4Fe-2S 0.51 41.0 2.90e-01 98.2% 41.3%
4677046 3625.1.1.1 ↗ alpha bundles › CRISPR RNA silencing complex Cmr2 subunit second helical domain › CRISPR RNA silencing complex Cmr2 subunit second helical domain › CRISPR RNA silencing complex Cmr2 subunit second helical domain › Cmr2_hel_dom2 0.51 36.0 3.42e-01 92.9% 60.0%
3734125 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.50 37.0 2.37e-01 82.1% 23.9%
D2 high residues 70-113
PDB
Domain cluster: representative
CATH (69)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3pf7B00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.78 58.0 3.29e-01 81.8% 27.2%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.78 61.0 4.91e-01 90.9% 44.6%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.78 63.0 4.97e-01 93.2% 44.7%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.77 61.0 4.17e-01 93.2% 25.1%
4a17E01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.76 62.0 5.21e-01 100.0% 96.5%
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.74 59.0 4.81e-01 90.9% 91.8%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 55.0 4.19e-01 81.8% 66.0%
4p1mB01 3.30.160.880 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Cell division protein ZapA protomer, N-terminal domain 0.73 56.0 5.67e-01 100.0% 88.9%
4p79A00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.73 61.0 4.06e-01 95.5% 65.7%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 55.0 4.08e-01 81.8% 54.1%
3aonA00 1.10.287.3240 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 54.0 3.49e-01 81.8% 76.1%
4m7xA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.71 53.0 4.21e-01 86.4% 39.6%
4hjhA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.71 60.0 4.69e-01 100.0% 98.0%
2a6aB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.71 55.0 4.19e-01 95.5% 34.5%
4hn3A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.70 53.0 3.16e-01 84.1% 33.4%
1i5eA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.69 54.0 3.46e-01 86.4% 20.7%
3bpvA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 48.0 3.37e-01 75.0% 62.0%
4c98A02 3.30.70.1900 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 55.0 3.97e-01 95.5% 92.0%
2qlzA02 6.10.250.2960 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.68 54.0 4.28e-01 86.4% 76.7%
2jl8102 3.30.160.850 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.67 47.0 4.69e-01 95.5% 73.3%
2qx2A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.66 57.0 3.41e-01 97.7% 49.4%
1t6aA02 3.30.310.120 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Rbstp2229 like protein 0.66 50.0 4.19e-01 84.1% 48.7%
1ti2B01 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 48.0 3.55e-01 84.1% 98.5%
2uvaG01 1.20.1050.120 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 54.0 3.90e-01 97.7% 33.1%
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.65 54.0 3.85e-01 100.0% 57.0%
3ulbA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.65 53.0 4.41e-01 95.5% 54.2%
4l80D00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.65 48.0 2.85e-01 81.8% 16.6%
1sfxB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 53.0 3.99e-01 90.9% 88.5%
1iowA02 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.65 46.0 3.20e-01 77.3% 61.7%
7t8tA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.64 53.0 3.88e-01 97.7% 33.6%
2zihC00 1.10.3630.10 Mainly Alpha › Orthogonal Bundle › yeast vps74-n-term truncation variant fold › yeast vps74-n-term truncation variant domain like 0.63 49.0 3.04e-01 88.6% 85.7%
1mhxA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.63 50.0 4.47e-01 90.9% 86.2%
2hhiA01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.61 49.0 3.81e-01 100.0% 48.3%
1itpA00 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.61 39.0 3.34e-01 79.5% 37.7%
3mweB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 41.0 2.94e-01 70.5% 94.9%
5hn3A00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.61 46.0 2.85e-01 93.2% 41.6%
1vrmA01 3.10.520.10 Alpha Beta › Roll › T-fold › ApbE-like domains 0.60 48.0 3.22e-01 100.0% 20.2%
1mhyD00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.60 51.0 2.88e-01 100.0% 23.1%
2q0oA01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.60 49.0 3.36e-01 95.5% 78.0%
2k4vA00 3.30.160.370 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064 0.59 44.0 3.44e-01 93.2% 36.0%
3zqmA00 6.10.140.2160 Special › Helix non-globular › Helix Hairpins › 0.58 39.0 3.60e-01 70.5% 86.4%
4ca1B02 2.60.210.10 Mainly Beta › Sandwich › Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A › Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 0.57 46.0 3.27e-01 88.6% 77.3%
1wmhB00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.57 47.0 3.99e-01 100.0% 100.0%
5ttjA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.57 48.0 3.11e-01 97.7% 25.3%
2hj1A00 3.10.20.280 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like 0.57 44.0 3.84e-01 93.2% 55.8%
5ucoA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.57 48.0 3.28e-01 95.5% 35.3%
2dqlA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 47.0 3.57e-01 97.7% 73.9%
5b55A01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 44.0 2.96e-01 88.6% 76.8%
1zxhA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.56 42.0 4.07e-01 90.9% 100.0%
7jgsG02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 40.0 3.17e-01 86.4% 34.7%
2wxfA02 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.56 47.0 3.54e-01 100.0% 75.6%
2giaB00 2.30.31.40 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › 0.56 48.0 3.35e-01 97.7% 92.5%
1jyoE00 4.10.1330.10 Few Secondary Structures › Irregular › non globular Virulence effector SptP fold › non globular Virulence effector SptP domain 0.56 44.0 3.49e-01 93.2% 41.2%
4kv2A00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.56 44.0 3.64e-01 97.7% 45.6%
4wiwA02 3.10.50.10 Alpha Beta › Roll › Chitinase A; domain 3 › 0.54 39.0 3.58e-01 86.4% 91.3%
3ephA03 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.54 42.0 4.08e-01 100.0% 85.2%
1c9fA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.54 43.0 3.66e-01 100.0% 81.6%
1wx8A00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 43.0 3.48e-01 95.5% 76.0%
4n01A01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.54 43.0 3.29e-01 95.5% 82.9%
2fnjB00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 43.0 3.49e-01 100.0% 89.8%
3h95A02 4.10.80.100 Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › 0.53 36.0 3.95e-01 77.3% 100.0%
2jxtA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.53 40.0 3.51e-01 90.9% 60.5%
2gk3A00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.53 41.0 2.71e-01 97.7% 87.4%
2v1xA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 41.0 3.08e-01 86.4% 56.4%
4kdiD00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 41.0 3.54e-01 90.9% 100.0%
1euvB00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 43.0 3.71e-01 100.0% 93.7%
8b4hA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.51 41.0 2.92e-01 100.0% 88.9%
2z86D02 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.51 43.0 2.73e-01 100.0% 60.8%
1ckmA01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.50 40.0 2.80e-01 88.6% 61.9%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2636124 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.82 63.0 3.89e-01 84.1% 52.1%
3433449 323.1.1.7 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase 0.81 60.0 3.56e-01 81.8% 68.4%
3684015 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.80 60.0 4.59e-01 81.8% 82.0%
4937853 3501.1.1.0 ↗ a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 0.79 67.0 5.81e-01 97.7% 100.0%
4948386 3501.1.1.1 ↗ a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.78 67.0 5.58e-01 100.0% 95.0%
3920672 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.78 59.0 4.63e-01 81.8% 52.2%
4987052 3501.1.1.1 ↗ a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.78 64.0 5.48e-01 95.5% 98.7%
3921728 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.78 58.0 4.28e-01 81.8% 48.7%
3958830 323.1.1.0 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.75 56.0 3.69e-01 81.8% 21.1%
4183868 878.1.1.1 ↗ a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.74 56.0 4.61e-01 81.8% 100.0%
4027687 330.3.1.0 ↗ a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like 0.74 57.0 5.46e-01 90.9% 78.2%
4817370 159.1.2.0 ↗ alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related 0.74 58.0 3.93e-01 86.4% 38.7%
4978596 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.73 53.0 3.81e-01 77.3% 81.6%
3586391 3937.1.1.2 ↗ alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin 0.73 55.0 3.30e-01 84.1% 13.5%
5010744 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.73 55.0 4.87e-01 84.1% 95.4%
4027686 252.2.1.0 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.72 59.0 5.58e-01 97.7% 85.5%
3991750 3937.1.1.2 ↗ alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin 0.71 53.0 3.18e-01 81.8% 14.8%
3898373 5001.1.1.3 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.69 56.0 3.51e-01 100.0% 38.2%
3628907 101.1.2.394 ↗ alpha arrays › HTH › HTH › winged helix domain › eWH_GTF3C1 0.69 55.0 2.99e-01 100.0% 5.5%
3466238 206.1.1.14 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.68 50.0 2.90e-01 81.8% 30.9%
3549652 109.26.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nucleoporin_C 0.67 57.0 3.07e-01 95.5% 14.2%
5060820 2484.1.1.18 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.66 55.0 3.17e-01 100.0% 60.0%
3931122 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.66 58.0 4.51e-01 100.0% 46.3%
3259141 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.66 46.0 4.20e-01 75.0% 100.0%
3590189 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.66 48.0 3.33e-01 81.8% 25.6%
3905302 284.1.3.8 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › Fy-3 0.66 51.0 4.16e-01 86.4% 55.3%
4991742 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.66 50.0 3.58e-01 84.1% 93.1%
3988478 857.1.1.1 ↗ a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.65 50.0 3.96e-01 100.0% 38.8%
4931277 101.1.2.14 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.65 56.0 3.83e-01 95.5% 54.2%
4977735 2004.1.1.19 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.65 54.0 3.57e-01 93.2% 49.1%
5062308 304.31.1.0 ↗ a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase 0.65 53.0 4.39e-01 100.0% 85.6%
5002955 2498.1.1.9 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.65 52.0 3.37e-01 95.5% 19.1%
3802871 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.63 48.0 3.61e-01 81.8% 42.9%
3679515 3115.1.1.1 ↗ a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.63 46.0 4.65e-01 84.1% 95.6%
3926235 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.61 45.0 3.86e-01 84.1% 47.5%
4980573 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.60 51.0 3.40e-01 100.0% 91.6%
3710585 881.1.1.0 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.60 48.0 3.67e-01 95.5% 36.7%
4987387 219.1.1.76 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF553 0.60 51.0 3.38e-01 100.0% 91.1%
4505972 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.60 51.0 3.11e-01 100.0% 20.6%
4874839 880.1.1.4 ↗ a+b duplicates or obligate multimers › ADC synthase › ADC synthase › ADC synthase › PF30495 0.60 44.0 2.64e-01 79.5% 15.7%
2418009 4955.1.1.0 ↗ a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.60 49.0 4.07e-01 90.9% 74.0%
3482807 277.1.1.0 ↗ a+b two layers › PX domain › PX domain › PX domain 0.59 50.0 3.85e-01 100.0% 78.7%
3520453 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.59 49.0 3.62e-01 100.0% 63.8%
4937773 3115.1.1.1 ↗ a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.59 46.0 4.29e-01 90.9% 79.3%
5050683 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 50.0 3.72e-01 100.0% 40.0%
4969863 3115.1.1.1 ↗ a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.58 45.0 3.91e-01 90.9% 61.3%
1815422 566.1.1.3 ↗ alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Pneumo_ncap 0.58 50.0 3.17e-01 97.7% 45.5%
3220485 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.58 50.0 2.99e-01 100.0% 27.0%
4867321 221.1.1.9 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PI3K_rbd,PIK3CG_ABD 0.57 45.0 3.07e-01 88.6% 54.9%
3575090 11.1.1.97 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set 0.57 51.0 3.32e-01 100.0% 25.0%
3325708 109.4.1.1254 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.56 44.0 2.67e-01 86.4% 15.0%
3277197 221.1.1.76 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA_2 0.56 40.0 3.28e-01 81.8% 50.5%
5078945 1.1.3.0 ↗ beta barrels › cradle loop barrel › RIFT-related › AbrB 0.55 39.0 3.49e-01 77.3% 95.4%
3472076 101.1.1.7 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Ribosomal_S18 0.54 44.0 3.19e-01 93.2% 38.5%
4995788 3218.1.1.0 ↗ a+b duplicates or obligate multimers › small terminase oligomerization domain › small terminase oligomerization domain › small terminase oligomerization domain 0.54 44.0 4.11e-01 97.7% 73.6%
3248306 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.54 43.0 3.64e-01 97.7% 89.4%
4964745 11.1.1.1420 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF7350 0.53 39.0 2.82e-01 84.1% 90.7%
5005403 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.53 39.0 3.46e-01 84.1% 86.7%
4930302 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.53 37.0 3.99e-01 77.3% 97.1%
4996269 844.1.1.0 ↗ beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain 0.52 41.0 2.71e-01 95.5% 82.7%
5005019 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.52 43.0 2.60e-01 100.0% 72.5%
3691685 1118.1.1.0 ↗ a+b complex topology › Anchorless fibronectin/fibrinogen binding protein C-terminal domain › Anchorless fibronectin/fibrinogen binding protein C-terminal domain › Anchorless fibronectin/fibrinogen binding protein C-terminal domain 0.51 41.0 3.11e-01 90.9% 95.5%