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IMGVR_UViG_3300038420_000249-3300038420-Ga0427954_0023460_3_1292

Arc-Vir

IMGVR_UViG_3300038420_000249-3300038420-Ga0427954_0023460_3_1292

Quality

83.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-100
PDB
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1d0qA00 3.90.580.10 Alpha Beta › Alpha-Beta Complex › DNA Primase; Chain A › Zinc finger, CHC2-type domain 0.80 64.0 6.25e-01 100.0% 77.5%
2k4jA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 39.0 3.83e-01 73.1% 57.1%
5bmnA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.58 42.0 4.44e-01 94.6% 85.5%
2g7jA00 3.90.1150.40 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Protein of unknown function DUF2002 0.57 42.0 4.00e-01 78.5% 97.3%
1z1bA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.57 34.0 3.90e-01 80.6% 93.0%
1ul7A00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.55 44.0 4.35e-01 98.9% 80.4%
1v5rA00 3.30.920.20 Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Gas2-like domain 0.54 41.0 4.06e-01 87.1% 77.3%
1av5A00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.54 37.0 3.49e-01 71.0% 85.0%
6whjD00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.54 46.0 3.30e-01 100.0% 93.5%
1zbtA02 3.30.70.1660 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 38.0 3.25e-01 74.2% 80.4%
3ottA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.53 44.0 3.21e-01 96.8% 93.0%
1li5B01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 40.0 2.97e-01 84.9% 47.3%
2nutA02 2.30.30.380 Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 0.51 26.0 3.04e-01 86.0% 68.9%
1r0vA01 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.50 35.0 3.81e-01 73.1% 90.9%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4539347 375.1.1.15 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-CHC2 0.82 67.0 6.59e-01 100.0% 81.0%
4680318 375.1.1.15 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-CHC2 0.81 66.0 6.70e-01 100.0% 88.9%
8015 375.1.1.15 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-CHC2 0.80 64.0 6.25e-01 100.0% 77.5%
4166935 375.1.1.15 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-CHC2 0.79 64.0 6.25e-01 100.0% 80.0%
4260807 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.75 54.0 6.06e-01 74.2% 100.0%
3274279 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.75 59.0 6.12e-01 87.1% 90.6%
5003468 375.1.1.15 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-CHC2 0.73 62.0 6.00e-01 100.0% 82.9%
4023805 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.71 58.0 6.09e-01 95.7% 96.5%
3772921 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.71 56.0 5.45e-01 83.9% 82.0%
4639076 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.70 53.0 5.35e-01 98.9% 78.9%
3928378 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.70 47.0 4.93e-01 73.1% 75.3%
3576759 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.70 50.0 5.57e-01 76.3% 100.0%
3412674 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.69 53.0 5.40e-01 81.7% 97.8%
3261011 375.1.1.85 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Auto_anti-p27 0.60 31.0 3.89e-01 77.4% 88.0%
3750942 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.60 27.0 3.55e-01 74.2% 78.0%
3540779 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.59 29.0 3.87e-01 71.0% 88.0%
4273381 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.59 41.0 3.82e-01 73.1% 79.2%
3173153 4.1.1.290 beta barrels › SH3 › SH3 › SH3 › AD 0.58 41.0 4.60e-01 100.0% 98.6%
3516693 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.57 44.0 4.16e-01 83.9% 93.9%
3556708 247.1.1.38 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › CPSF73-100_C 0.56 41.0 4.51e-01 98.9% 98.7%
3403609 247.1.1.38 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › CPSF73-100_C 0.56 42.0 4.49e-01 100.0% 94.9%
3794324 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.54 34.0 3.73e-01 98.9% 82.9%
3226400 4184.1.1.2 beta barrels › MFPT repeat › MFPT repeat › MFPT repeat › MFP2b 0.54 35.0 3.63e-01 90.3% 70.0%
4928595 101.1.11.0 alpha arrays › HTH › HTH › Ribbon-helix-helix 0.53 34.0 3.33e-01 93.5% 57.1%
5014493 331.3.1.12 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › STK_08120-like 0.53 46.0 3.54e-01 100.0% 45.2%
3985577 101.1.2.8 alpha arrays › HTH › HTH › winged helix domain › Trans_reg_C 0.52 37.0 3.50e-01 92.5% 60.2%
3628498 386.1.1.4 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED 0.51 32.0 3.63e-01 98.9% 84.3%
3363052 386.1.1.207 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED_2 0.51 29.0 3.27e-01 82.8% 75.4%
3899940 331.4.1.9 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › CPSF73-100_C 0.51 39.0 4.14e-01 100.0% 97.5%
D2 high residues 123-181
PDB
Domain cluster: representative
CATH (66)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4jglA00 2.40.128.530 Mainly Beta › Beta Barrel › Lipocalin › 0.73 51.0 3.69e-01 71.2% 31.6%
1o97C00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.70 43.0 2.82e-01 96.6% 14.3%
1gutA00 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.69 43.0 4.12e-01 93.2% 55.2%
3zqsA01 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.68 51.0 4.51e-01 100.0% 54.5%
2gu1A01 3.10.450.350 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.66 47.0 4.17e-01 100.0% 51.1%
4ghbA00 2.40.160.190 Mainly Beta › Beta Barrel › Porin › 0.63 53.0 3.52e-01 96.6% 67.8%
2fwvA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.63 47.0 3.26e-01 93.2% 25.3%
2y1sA00 2.30.60.10 Mainly Beta › Roll › HIV-inactivating Protein, Cyanovirin-n › Cyanovirin-N 0.63 45.0 3.82e-01 79.7% 49.1%
4pj2A00 2.40.128.460 Mainly Beta › Beta Barrel › Lipocalin › Periplasmic lysozyme inhibitor of I-type lysozyme 0.62 46.0 3.61e-01 96.6% 38.0%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 55.0 3.71e-01 100.0% 95.0%
2wsuA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.61 43.0 3.28e-01 94.9% 31.7%
2hzrA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.60 51.0 3.74e-01 94.9% 41.0%
4r03A00 2.40.128.720 Mainly Beta › Beta Barrel › Lipocalin › 0.60 49.0 4.15e-01 94.9% 99.1%
5iroD00 2.60.40.3530 Mainly Beta › Sandwich › Immunoglobulin-like › 0.60 43.0 3.59e-01 74.6% 77.5%
2au3A02 3.90.980.10 Alpha Beta › Alpha-Beta Complex › DNA primase DNAg catalytic core, N-terminal domain › DNA primase, catalytic core, N-terminal domain 0.60 41.0 3.26e-01 96.6% 33.1%
1v5vA02 3.30.70.1400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aminomethyltransferase beta-barrel domains 0.60 42.0 3.71e-01 100.0% 48.9%
1xfsA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.60 52.0 3.78e-01 100.0% 36.4%
3dtdD00 2.60.40.1880 Mainly Beta › Sandwich › Immunoglobulin-like › Invasion associated locus B (IalB) protein 0.60 51.0 3.89e-01 98.3% 51.0%
5c7qB00 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.59 50.0 3.61e-01 98.3% 63.9%
3pieB05 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.59 41.0 4.07e-01 93.2% 68.8%
5w8mA00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.58 40.0 2.79e-01 71.2% 36.2%
3ro6C01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.58 49.0 4.10e-01 96.6% 83.0%
5yjwA00 3.50.50.100 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › 0.58 42.0 2.50e-01 78.0% 51.3%
1vhzA01 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.58 48.0 3.50e-01 94.9% 65.2%
1xe4A01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.58 46.0 3.34e-01 88.1% 48.2%
2py5A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.58 43.0 3.21e-01 86.4% 69.6%
3dg6A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.58 49.0 4.00e-01 96.6% 84.2%
3gxwC00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.57 48.0 4.09e-01 94.9% 75.0%
4xrtA02 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 49.0 3.65e-01 100.0% 51.2%
1yx2A02 3.30.70.1400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aminomethyltransferase beta-barrel domains 0.57 40.0 3.61e-01 100.0% 52.3%
3f4lA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.57 45.0 3.20e-01 94.9% 73.5%
2zgyA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 49.0 3.50e-01 96.6% 48.9%
1h91A00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.56 46.0 3.37e-01 94.9% 38.3%
1ci0B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.56 48.0 3.37e-01 98.3% 67.6%
2il5A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.56 48.0 3.55e-01 98.3% 49.4%
1wsrA02 3.30.70.1400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aminomethyltransferase beta-barrel domains 0.56 40.0 3.51e-01 100.0% 49.5%
2avwD01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 45.0 3.56e-01 96.6% 49.6%
6pxcA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.56 47.0 3.96e-01 96.6% 72.1%
3dorA02 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.56 40.0 3.35e-01 78.0% 96.3%
3ugfB02 2.60.120.560 Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 0.56 47.0 3.46e-01 100.0% 36.2%
1st8A01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.55 48.0 3.03e-01 100.0% 23.4%
3girA02 3.30.70.1400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aminomethyltransferase beta-barrel domains 0.55 39.0 3.50e-01 100.0% 52.3%
3d8pB00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 43.0 3.19e-01 88.1% 52.5%
2f86B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 46.0 3.67e-01 100.0% 82.9%
2iafA00 3.30.1330.90 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › D-3-phosphoglycerate dehydrogenase; domain 3 0.54 47.0 3.63e-01 100.0% 86.4%
1a31A03 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.54 38.0 2.91e-01 96.6% 30.0%
1wv4B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.54 45.0 3.44e-01 98.3% 55.8%
1t9mA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.54 45.0 3.20e-01 100.0% 93.6%
6mlyB01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.54 43.0 2.86e-01 100.0% 20.6%
4js8A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 44.0 3.98e-01 100.0% 92.1%
4qrlA00 2.40.128.280 Mainly Beta › Beta Barrel › Lipocalin › 0.53 44.0 3.62e-01 94.9% 72.7%
3h51A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 45.0 3.46e-01 100.0% 75.4%
2xg5A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 45.0 3.92e-01 98.3% 89.1%
1b69A00 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.53 40.0 3.82e-01 93.2% 71.0%
3pg1A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 44.0 3.55e-01 100.0% 76.0%
2bcqA03 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.52 39.0 3.30e-01 89.8% 91.9%
3plsA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 43.0 3.72e-01 100.0% 80.8%
1lrzA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.52 41.0 3.31e-01 98.3% 74.1%
4ew6A02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.51 39.0 2.92e-01 91.5% 38.6%
2l2fA00 2.30.60.10 Mainly Beta › Roll › HIV-inactivating Protein, Cyanovirin-n › Cyanovirin-N 0.51 42.0 3.63e-01 100.0% 96.3%
2cy5A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 43.0 3.38e-01 94.9% 48.8%
1u4dA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 42.0 3.88e-01 100.0% 89.2%
3mmyA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 45.0 2.79e-01 100.0% 18.6%
2ft0A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 43.0 2.98e-01 100.0% 51.8%
1gxcA00 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.50 40.0 3.31e-01 91.5% 60.3%
1xjvA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.50 41.0 3.22e-01 94.9% 66.9%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5072494 844.1.1.2 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.85 53.0 3.69e-01 93.2% 21.3%
4240860 3421.1.1.1 a+b complex topology › Yos9 dimerization domain › Yos9 dimerization domain › Yos9 dimerization domain › Yos9_DD 0.80 48.0 3.70e-01 93.2% 28.1%
5075159 844.1.1.2 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.80 52.0 3.73e-01 98.3% 24.2%
1562389 3308.2.1.0 beta duplicates or obligate multimers › periplasmic lysozyme inhibitor of I-type lysozyme-like › XAC2610 protein › XAC2610 protein 0.74 50.0 3.35e-01 100.0% 19.6%
3941442 2.4.1.2 beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2 0.73 46.0 3.55e-01 93.2% 29.7%
3658595 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.69 50.0 4.73e-01 94.9% 64.3%
3342267 9.1.1.0 beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.68 56.0 3.89e-01 93.2% 28.9%
3589473 4.8.1.0 beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.68 44.0 4.03e-01 96.6% 48.8%
5053021 4252.1.1.0 beta barrels › AttH-like › AttH-like › AttH-like 0.67 47.0 4.15e-01 74.6% 90.0%
4960511 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.67 58.0 3.81e-01 100.0% 44.4%
3218206 9.1.1.0 beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.66 53.0 3.76e-01 88.1% 62.2%
3189694 9.1.1.33 beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › DUF1365 0.65 58.0 3.65e-01 98.3% 57.9%
4302400 5.1.7.2 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 10-bladed › Sortilin-Vps10 0.65 47.0 2.73e-01 100.0% 8.5%
3950877 3459.1.1.0 beta sandwiches › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule 0.64 42.0 4.14e-01 93.2% 61.5%
3182013 216.1.1.1 a+b two layers › UBC-like › UBC-like › UBC-like › UQ_con 0.64 55.0 3.92e-01 100.0% 32.6%
1872648 2003.1.2.40 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_oxidored 0.63 43.0 2.67e-01 71.2% 17.6%
3476991 269.1.1.3 a+b complex topology › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › COLFI 0.63 46.0 3.06e-01 100.0% 18.1%
3511356 4056.1.1.1 beta barrels › Barrel domain in upper collar protein › Barrel domain in upper collar protein › Barrel domain in upper collar protein › Phage_prot_Gp6 0.62 55.0 4.52e-01 98.3% 86.7%
3255969 2004.1.1.174 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Elong_Iki1 0.62 56.0 3.55e-01 100.0% 93.2%
4236717 2.4.1.2 beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2 0.62 45.0 3.57e-01 96.6% 38.3%
3730841 2004.1.1.174 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Elong_Iki1 0.62 54.0 3.40e-01 100.0% 92.7%
3301582 844.1.1.2 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.62 53.0 3.62e-01 93.2% 30.3%
4159881 220.1.1.197 beta barrels › PH domain-like › PH domain-like › PH domain-like › PF28623 0.62 56.0 4.76e-01 100.0% 71.6%
3248828 9.1.1.33 beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › DUF1365 0.62 55.0 3.55e-01 98.3% 56.7%
3367161 9.1.1.0 beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.62 56.0 4.16e-01 100.0% 75.2%
4927548 331.3.1.9 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › AHSA1 0.61 51.0 4.04e-01 93.2% 53.3%
3782254 12.3.1.9 beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_81 0.61 49.0 3.08e-01 91.5% 43.3%
3468906 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.61 54.0 4.75e-01 98.3% 70.6%
185181 11.1.1.90 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › IalB 0.59 51.0 3.90e-01 98.3% 51.4%
3183098 2003.1.2.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_2 0.59 44.0 2.82e-01 84.7% 89.3%
3974211 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.59 50.0 3.74e-01 93.2% 76.4%
4026147 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.59 52.0 3.71e-01 100.0% 67.2%
5065386 4252.1.1.0 beta barrels › AttH-like › AttH-like › AttH-like 0.59 51.0 4.02e-01 100.0% 67.7%
4961432 218.1.1.1 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › MR_MLE_N 0.59 51.0 4.30e-01 94.9% 95.8%
5076916 4252.1.1.0 beta barrels › AttH-like › AttH-like › AttH-like 0.58 50.0 3.92e-01 100.0% 74.6%
5052651 4252.1.1.12 beta barrels › AttH-like › AttH-like › AttH-like › DUF7064 0.58 51.0 3.97e-01 100.0% 68.5%
3625571 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.57 47.0 3.02e-01 100.0% 23.2%
4959178 4252.1.1.12 beta barrels › AttH-like › AttH-like › AttH-like › DUF7064 0.57 50.0 3.99e-01 100.0% 72.5%
3243587 2484.1.1.200 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FTH 0.57 49.0 3.13e-01 100.0% 25.7%
3490910 304.107.1.1 a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › GCV_T 0.55 39.0 2.86e-01 100.0% 25.7%
3283322 213.1.1.1 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.55 44.0 3.21e-01 88.1% 55.8%
3996533 11.1.3.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Cu,Zn superoxide dismutase-like 0.55 49.0 3.90e-01 98.3% 78.3%
3639760 2.1.1.52 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Stn1 0.55 47.0 3.38e-01 98.3% 43.9%
4132235 2002.1.1.120 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.55 47.0 3.03e-01 98.3% 33.3%
3170091 243.1.1.116 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF29059 0.55 48.0 3.95e-01 100.0% 61.8%
3330582 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.54 47.0 3.76e-01 100.0% 56.0%
4939185 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.54 48.0 3.83e-01 100.0% 56.7%
3629780 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.54 45.0 2.83e-01 100.0% 22.2%
4975431 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.54 45.0 4.00e-01 98.3% 90.0%
3275009 220.1.1.8 beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.54 46.0 3.44e-01 94.9% 42.7%
5049738 2.1.1.94 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › TLP1_add_C 0.53 48.0 4.31e-01 100.0% 88.7%
3264346 213.1.1.1 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.53 42.0 2.89e-01 88.1% 67.7%
3969569 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.53 46.0 4.59e-01 100.0% 91.7%
4401040 213.1.1.27 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_7 0.53 42.0 3.67e-01 86.4% 75.6%
3954042 2.1.1.94 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › TLP1_add_C 0.53 47.0 4.42e-01 100.0% 85.1%
4000395 2007.1.1.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like 0.53 42.0 3.07e-01 98.3% 46.7%
3957296 298.1.1.24 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 0.53 43.0 3.28e-01 93.2% 46.0%
3938332 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.53 42.0 2.89e-01 100.0% 30.0%
3744517 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.52 46.0 3.63e-01 98.3% 87.5%
2673496 11.1.1.192 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › V-set_2 0.52 35.0 3.04e-01 71.2% 84.8%
3223910 210.1.2.8 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › TANGO2 0.51 44.0 2.85e-01 94.9% 92.4%
3394747 298.1.1.24 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 0.51 40.0 3.29e-01 93.2% 54.4%
3725926 2.1.1.94 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › TLP1_add_C 0.50 45.0 3.98e-01 100.0% 80.0%
D3 high residues 190-328
PDB
CATH (74)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2au3A03 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.83 69.0 7.30e-01 100.0% 96.8%
5gujA02 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.82 69.0 7.31e-01 100.0% 96.8%
5vazA02 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.81 70.0 7.29e-01 100.0% 96.9%
1t6t200 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.76 51.0 5.69e-01 81.3% 85.5%
3hbaA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.70 48.0 5.24e-01 88.5% 85.2%
1darA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 57.0 4.60e-01 92.1% 93.0%
2wojC00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 54.0 4.27e-01 88.5% 90.1%
4kxwA03 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.65 55.0 5.69e-01 96.4% 95.5%
7o0aD01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.65 54.0 4.65e-01 88.5% 68.5%
1zzgA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.65 53.0 4.40e-01 87.8% 58.5%
1yt8A02 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.64 40.0 4.50e-01 84.9% 80.6%
3fj1A02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.64 51.0 5.23e-01 89.2% 86.8%
7uvpA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 53.0 4.32e-01 90.6% 99.6%
3c3jA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.63 52.0 4.68e-01 88.5% 70.6%
3fdjA01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.63 47.0 5.23e-01 91.4% 99.1%
5h3hB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.63 57.0 4.60e-01 100.0% 98.5%
1dg3A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 54.0 4.58e-01 95.7% 95.4%
1f6bB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 53.0 4.89e-01 91.4% 90.0%
3tbfA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.62 52.0 5.08e-01 88.5% 83.2%
4rncA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.62 56.0 4.50e-01 100.0% 93.2%
1oi2A01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.62 56.0 5.23e-01 98.6% 84.4%
5egnA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.62 55.0 4.51e-01 98.6% 98.5%
1td2A00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.62 52.0 4.10e-01 90.6% 83.6%
1u9yA02 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.62 42.0 4.49e-01 93.5% 78.2%
3d1pA00 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.62 44.0 4.67e-01 84.9% 84.2%
3nwoA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.61 55.0 4.34e-01 100.0% 96.3%
3fxaA00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.61 50.0 4.52e-01 87.8% 68.1%
5eswB00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 47.0 4.27e-01 81.3% 72.5%
4q6bA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 46.0 4.70e-01 93.5% 82.1%
4fhzA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.61 54.0 4.66e-01 98.6% 96.8%
3k6kA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.60 54.0 4.27e-01 100.0% 80.8%
1r1dA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.60 53.0 4.43e-01 96.4% 96.7%
4s1wB01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.60 50.0 4.44e-01 89.2% 64.0%
6fufB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 52.0 4.75e-01 93.5% 95.0%
3jr7A01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.59 46.0 4.89e-01 92.1% 94.9%
1u3dA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.59 42.0 4.02e-01 72.7% 79.5%
4wy5A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 53.0 4.09e-01 100.0% 79.4%
5g5tA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 48.0 4.63e-01 94.2% 77.0%
1r88A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 53.0 4.32e-01 100.0% 95.5%
4m88A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 48.0 4.79e-01 93.5% 83.9%
2ajtA01 3.40.50.10940 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 50.0 4.70e-01 94.2% 92.6%
1gqyB02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.59 51.0 4.46e-01 96.4% 92.6%
1p3y100 3.40.50.1950 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like 0.58 50.0 4.72e-01 93.5% 96.5%
6kd0A01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 48.0 3.70e-01 89.2% 73.4%
3dmnA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 44.0 4.24e-01 92.1% 68.3%
1fjhA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 50.0 4.23e-01 94.2% 93.2%
3f67A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 52.0 4.34e-01 98.6% 95.4%
7yosA01 3.90.1640.30 Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › 0.58 47.0 4.24e-01 87.1% 66.5%
5jnmA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 51.0 4.53e-01 97.1% 92.1%
3nyiB01 3.40.50.10170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 49.0 4.72e-01 91.4% 97.5%
3e03A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 49.0 4.00e-01 92.8% 86.1%
3r0vA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 52.0 4.24e-01 99.3% 96.1%
1flaA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.58 47.0 4.79e-01 88.5% 97.1%
2acfB00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.57 41.0 3.86e-01 74.1% 74.0%
1jkmA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 48.0 3.60e-01 92.8% 71.5%
4o5aA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 44.0 4.50e-01 93.5% 84.2%
1wd5A01 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 42.0 4.19e-01 81.3% 74.0%
1mqsA02 3.40.50.1910 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sec1/Munc18 (SM) protein, domain 2 0.55 40.0 3.55e-01 75.5% 71.2%
4xrpA02 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.55 39.0 4.05e-01 91.4% 78.3%
3ggdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 47.0 3.93e-01 93.5% 76.5%
2w2gB01 3.40.220.30 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Nsp3, SUD-N subdomain 0.55 39.0 4.07e-01 73.4% 87.4%
3s5jA02 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 44.0 4.51e-01 92.1% 87.6%
2qorA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 46.0 4.73e-01 92.1% 96.2%
3zrpA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.54 45.0 3.73e-01 90.6% 58.5%
1uagA02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.54 47.0 4.20e-01 96.4% 92.4%
3qyfA01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.54 47.0 4.44e-01 95.0% 97.0%
4rweA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 45.0 4.31e-01 91.4% 81.8%
2o2gA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 45.0 3.93e-01 93.5% 89.8%
3g1wA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 43.0 4.24e-01 92.8% 82.9%
5gvrA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 45.0 3.84e-01 95.0% 61.1%
4rxtA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 42.0 4.04e-01 91.4% 77.2%
4r16A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 39.0 3.53e-01 93.5% 58.2%
1vm6B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 43.0 4.39e-01 92.1% 94.8%
3pkiA01 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.50 41.0 3.61e-01 87.1% 82.8%
ECOD (82)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4504313 2006.1.3.6 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.84 70.0 7.36e-01 100.0% 95.2%
4345684 2006.1.3.6 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.82 66.0 7.11e-01 97.8% 97.5%
4305698 2006.1.3.6 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.81 66.0 6.98e-01 98.6% 94.4%
4437562 2006.1.3.6 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.78 65.0 6.82e-01 100.0% 96.0%
4041525 2006.1.3.6 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.78 62.0 6.71e-01 95.0% 96.7%
4426393 2006.1.3.6 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.77 65.0 6.74e-01 100.0% 94.6%
4933255 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.76 54.0 5.67e-01 82.7% 80.0%
5024065 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.75 60.0 6.09e-01 93.5% 85.9%
5081727 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.74 54.0 5.66e-01 83.5% 82.4%
5041173 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.74 54.0 5.65e-01 83.5% 82.4%
5063458 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.73 52.0 5.54e-01 83.5% 81.6%
5060457 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.71 53.0 5.47e-01 85.6% 81.5%
3838295 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.71 58.0 6.29e-01 93.5% 99.2%
4956612 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.70 50.0 5.38e-01 83.5% 85.0%
4971254 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.70 59.0 6.08e-01 87.8% 100.0%
5008810 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.70 62.0 6.30e-01 93.5% 96.3%
4392313 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.69 61.0 5.92e-01 93.5% 98.7%
5071766 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.69 61.0 5.80e-01 93.5% 95.6%
4638791 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.69 60.0 5.41e-01 92.1% 96.8%
1572168 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.69 61.0 5.57e-01 93.5% 97.7%
5001224 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.68 61.0 5.35e-01 93.5% 99.5%
5036017 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.68 61.0 5.03e-01 93.5% 74.3%
4418350 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.68 60.0 5.30e-01 93.5% 97.4%
4987292 2004.1.1.67 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CbiA 0.68 58.0 4.79e-01 90.6% 97.9%
5036375 2007.6.1.5 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.67 52.0 4.96e-01 87.8% 70.0%
4476434 2007.6.1.5 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.66 51.0 4.84e-01 89.2% 67.9%
2010233 7590.1.1.2 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi 0.65 56.0 5.06e-01 94.2% 69.4%
3587394 2007.6.1.4 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS 0.65 54.0 4.79e-01 88.5% 71.8%
5004973 2004.1.1.175 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ParA 0.65 56.0 4.78e-01 92.8% 98.6%
4209046 2004.1.1.226 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADDB_N 0.64 51.0 3.19e-01 84.2% 81.6%
3271985 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.63 55.0 5.14e-01 94.2% 93.1%
4154621 2007.6.1.3 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › PGI 0.63 53.0 4.66e-01 89.2% 71.2%
3386587 2007.6.1.3 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › PGI 0.63 53.0 4.71e-01 89.2% 74.4%
5063527 2004.1.1.85 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ArsA_ATPase 0.63 52.0 4.28e-01 87.8% 100.0%
3636733 7568.1.1.0 a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.63 50.0 5.20e-01 93.5% 89.9%
3600369 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.63 57.0 4.32e-01 100.0% 86.1%
3612327 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 55.0 4.38e-01 97.1% 94.6%
3703740 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 54.0 4.33e-01 95.7% 94.4%
4018644 7579.1.1.6 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.62 56.0 4.33e-01 98.6% 97.7%
4020196 7579.1.1.18 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_2 0.62 56.0 4.51e-01 100.0% 97.0%
3472154 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 53.0 4.89e-01 93.5% 95.0%
4289517 2003.6.1.5 a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › Phos_pyr_kin 0.62 52.0 4.12e-01 91.4% 83.9%
None 0.61 52.0 4.09e-01 90.6% 83.5%
4071568 2004.1.1.67 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CbiA 0.61 52.0 4.34e-01 92.8% 92.9%
4451442 7579.1.1.6 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.61 55.0 4.27e-01 100.0% 94.8%
3663267 7579.1.1.3 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9 0.61 54.0 4.32e-01 100.0% 85.2%
3282986 7579.1.1.42 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4 0.60 54.0 4.33e-01 99.3% 97.5%
3724886 7579.1.1.36 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_3 0.60 54.0 4.14e-01 100.0% 88.5%
3672327 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.60 52.0 5.07e-01 92.8% 98.0%
3934605 7579.1.1.18 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_2 0.60 53.0 4.63e-01 98.6% 99.1%
3353683 7579.1.1.96 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9, Abhydrolase_1 0.60 54.0 4.21e-01 100.0% 75.7%
4030806 7579.1.1.36 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_3 0.60 53.0 4.24e-01 98.6% 91.9%
3457868 7579.1.1.36 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_3 0.60 50.0 3.69e-01 89.9% 66.3%
3826287 7579.1.1.102 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9, Hydrolase_4 0.60 53.0 4.21e-01 100.0% 80.5%
3853982 2007.9.1.7 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › NPHP3 0.60 50.0 4.82e-01 91.4% 93.8%
3499670 7579.1.1.6 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.59 53.0 4.01e-01 100.0% 77.1%
3736064 2003.1.5.114 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_34 0.59 51.0 3.93e-01 94.2% 67.2%
4990263 2005.1.1.3 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.58 38.0 3.86e-01 89.9% 66.4%
4031091 2004.1.1.159 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M 0.58 50.0 4.15e-01 93.5% 88.8%
3971246 7579.1.1.3 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9 0.58 52.0 4.16e-01 100.0% 85.9%
4117604 2007.1.13.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Lumazine synthase › DMRL_synthase 0.58 48.0 4.59e-01 92.8% 80.6%
None 0.58 51.0 4.02e-01 100.0% 88.7%
3280422 7579.1.1.24 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › LIP 0.57 51.0 3.80e-01 99.3% 83.8%
3735314 7579.1.1.3 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9 0.57 51.0 4.06e-01 100.0% 81.0%
3708970 2007.1.2.28 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_A-cyclase_1 0.57 45.0 4.32e-01 89.2% 72.5%
3955949 7565.1.1.1 a/b three-layered sandwiches › Resolvase-like › Resolvase-like › Resolvase-like › Resolvase 0.57 41.0 4.00e-01 77.0% 67.1%
3733860 2006.1.1.28 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › APP1_cat 0.57 48.0 3.86e-01 92.1% 71.8%
4953333 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.56 46.0 4.12e-01 91.4% 62.6%
5001177 2007.1.11.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › L-fucose isomerase, N-terminal and second domains 0.56 46.0 4.66e-01 88.5% 94.1%
4306615 2004.1.1.49 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase 0.55 48.0 4.00e-01 95.0% 77.6%
4500970 2007.1.2.42 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › PF29770 0.55 48.0 4.33e-01 93.5% 73.0%
4883908 7579.1.1.24 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › LIP 0.55 47.0 3.37e-01 93.5% 72.5%
4141736 7579.1.1.47 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › BD-FAE 0.54 46.0 3.47e-01 94.2% 91.4%
3947733 2006.1.1.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.54 38.0 3.90e-01 89.9% 76.9%
4991816 2007.1.11.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › L-fucose isomerase, N-terminal and second domains 0.53 44.0 4.57e-01 92.8% 96.2%
5045094 7523.1.1.3 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5 0.53 41.0 3.46e-01 82.0% 62.6%
4985803 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 46.0 4.35e-01 97.1% 78.8%
4879055 2484.1.1.21 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › BcrAD_BadFG 0.52 41.0 3.73e-01 84.2% 97.4%
3740720 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.52 44.0 3.55e-01 92.8% 48.6%
5049929 2003.1.5.24 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Met_10 0.51 44.0 3.83e-01 93.5% 74.8%
4990533 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.51 44.0 3.98e-01 94.2% 75.3%
3216540 2498.1.1.69 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › PIG-S 0.50 41.0 4.03e-01 91.4% 79.4%
D4 medium residues 361-430
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13481.13 best AAA_25 50.6 2.70e-13 100.0% 34.4%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kg4A00 3.30.70.2660 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 46.0 3.46e-01 84.3% 58.7%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5068261 2004.1.1.200 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_25 0.88 79.0 5.23e-01 95.7% 28.2%
3196539 2002.1.1.67 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Pro_dh 0.60 49.0 3.08e-01 92.9% 51.2%
4623172 7510.1.1.2 a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › PTA_PTB 0.56 41.0 3.26e-01 78.6% 53.5%