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IMGVR_UViG_3300038427_000499-3300038427-Ga0427947_002493_11050_12411

Arc-Vir

IMGVR_UViG_3300038427_000499-3300038427-Ga0427947_002493_11050_12411

Quality

89.1 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-160
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4q20A02 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.75 48.0 4.93e-01 83.2% 67.1%
3sl2A00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.72 48.0 4.97e-01 83.9% 71.0%
5idmA00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.69 52.0 4.92e-01 83.9% 67.8%
1v8cA02 3.30.1370.80 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › Molybdopterin cofactor biosynthesis MoaD-related, C-terminal domain 0.57 27.0 3.51e-01 87.1% 81.2%
1n08A00 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.53 31.0 3.12e-01 98.7% 57.1%
4dj3B01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.52 35.0 4.11e-01 92.3% 96.4%
3lidA03 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.51 31.0 3.81e-01 91.6% 96.9%
3otlA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 39.0 3.98e-01 87.7% 81.0%
2pcsA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 37.0 3.77e-01 89.0% 77.0%
2nn5A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.50 35.0 3.39e-01 91.6% 63.2%
1w0nA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.50 32.0 3.62e-01 77.4% 82.5%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5053445 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.87 77.0 7.65e-01 91.6% 89.4%
4073606 3703.1.1.0 a/b three-layered sandwiches › HSP90 C-terminal a/b domain › HSP90 C-terminal a/b domain › HSP90 C-terminal a/b domain 0.87 72.0 6.16e-01 85.8% 60.0%
3735005 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.86 76.0 6.46e-01 91.6% 87.0%
4585079 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.78 50.0 5.10e-01 83.9% 66.0%
3970441 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.78 49.0 5.07e-01 83.2% 67.6%
4419300 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.77 50.0 4.93e-01 83.2% 62.6%
3969529 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.76 49.0 5.05e-01 83.9% 67.3%
4102143 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.75 51.0 5.16e-01 83.9% 69.0%
4517208 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.75 50.0 4.95e-01 83.9% 65.0%
5018927 225.1.1.7 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.74 63.0 5.64e-01 89.0% 78.6%
5045629 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.74 48.0 4.99e-01 83.2% 69.7%
5027973 225.1.1.7 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.73 63.0 5.65e-01 89.7% 74.6%
4221311 225.1.1.7 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.73 62.0 5.43e-01 89.0% 69.1%
4015094 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.71 65.0 5.50e-01 96.8% 70.2%
3286344 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.71 62.0 5.42e-01 92.9% 81.8%
4999860 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.70 50.0 5.01e-01 83.9% 70.6%
4980661 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.69 49.0 4.82e-01 83.9% 68.5%
3196992 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.66 58.0 5.15e-01 92.9% 67.0%
4319179 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.63 52.0 5.16e-01 85.2% 95.0%
3514475 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.63 52.0 5.11e-01 85.8% 97.0%
4175269 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.62 53.0 3.69e-01 88.4% 50.3%
4376160 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.62 51.0 5.00e-01 85.2% 88.5%
4973553 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.61 51.0 5.24e-01 86.5% 98.0%
4452292 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.61 50.0 5.12e-01 85.2% 94.8%
4065430 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.61 51.0 5.17e-01 86.5% 95.4%
3947118 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.61 50.0 4.97e-01 84.5% 91.8%
4973784 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.60 52.0 3.73e-01 89.0% 44.0%
5065474 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.60 50.0 5.11e-01 86.5% 95.3%
4051064 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.60 50.0 4.78e-01 86.5% 90.9%
4961468 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.60 50.0 5.15e-01 86.5% 94.5%
3978888 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.60 49.0 4.92e-01 85.8% 93.7%
3565109 331.18.1.4 a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc › COR-B 0.59 37.0 3.51e-01 92.3% 50.8%
3988671 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.58 49.0 5.00e-01 87.1% 96.7%
5049059 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.57 32.0 3.47e-01 87.1% 63.7%
5038572 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.56 40.0 4.12e-01 85.8% 76.0%
408891 331.3.1.9 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › AHSA1 0.52 39.0 4.00e-01 87.7% 80.0%
4944403 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.51 31.0 3.30e-01 89.0% 66.7%
139111 223.1.1.47 a+b three layers › Profilin-like › sensor domains › sensor domains › HK_sensor_dom_bact 0.51 31.0 3.70e-01 91.6% 88.6%
3622225 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.51 25.0 3.23e-01 94.8% 85.0%
5040587 331.3.1.11 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.51 37.0 3.72e-01 89.0% 74.2%
2634554 331.3.1.1 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Bet_v_1 0.51 40.0 3.94e-01 88.4% 78.5%
4999755 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.51 33.0 3.41e-01 92.9% 69.4%
4883183 331.3.1.11 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.50 40.0 3.98e-01 93.5% 79.5%
D2 high residues 349-441
PDB
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4jiuA00 3.30.2010.10 Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" 0.81 57.0 5.44e-01 82.8% 63.8%
4jixB00 3.30.2010.10 Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" 0.78 57.0 5.50e-01 86.0% 68.3%
1eb6A00 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.66 57.0 4.58e-01 94.6% 77.4%
3lmcA00 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.65 56.0 4.49e-01 95.7% 79.1%
3k7lA01 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.62 53.0 4.20e-01 95.7% 69.0%
4lrjA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.57 34.0 3.53e-01 97.8% 62.1%
1wu2A01 3.40.980.10 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › MoaB/Mog-like domain 0.57 48.0 4.16e-01 95.7% 80.8%
3kd9A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 43.0 3.59e-01 83.9% 90.4%
1i1qB00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.55 46.0 3.77e-01 94.6% 96.8%
1gpwD00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.55 46.0 3.69e-01 95.7% 96.5%
4p5pA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.54 46.0 3.53e-01 95.7% 97.3%
3mgkB00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.54 46.0 3.62e-01 95.7% 83.1%
2ab0A00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.53 46.0 3.64e-01 95.7% 86.2%
3fbtA01 3.40.50.10860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 0.53 46.0 4.06e-01 97.8% 80.0%
4p1zA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 44.0 4.00e-01 95.7% 88.2%
6ks6Z02 3.30.260.10 Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain 0.50 32.0 3.14e-01 90.3% 56.1%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5053447 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.84 75.0 6.82e-01 95.7% 74.6%
4194668 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.82 71.0 6.78e-01 95.7% 81.0%
4458442 2498.1.1.39 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like 0.81 74.0 6.92e-01 98.9% 81.8%
3386105 2498.1.1.17 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YgjP-like 0.76 59.0 5.21e-01 91.4% 58.5%
3957469 2498.1.1.17 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YgjP-like 0.76 59.0 4.97e-01 91.4% 50.7%
3519421 2498.1.1.62 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M76 0.73 61.0 4.90e-01 89.2% 48.8%
3983198 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.72 60.0 6.21e-01 88.2% 98.8%
4967466 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.72 57.0 5.50e-01 89.2% 74.3%
4959203 2498.1.1.160 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_MA_2 0.71 65.0 4.81e-01 100.0% 48.9%
3877262 2498.1.1.62 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M76 0.71 59.0 5.31e-01 88.2% 65.6%
3405450 2498.1.1.62 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M76 0.69 64.0 4.76e-01 100.0% 49.5%
3589463 2498.1.1.29 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 0.66 50.0 4.17e-01 81.7% 47.7%
4412026 2498.1.1.46 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Aspzincin_M35 0.65 57.0 4.61e-01 95.7% 75.4%
3799699 2498.1.1.93 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › PF29156 0.65 59.0 4.03e-01 100.0% 41.9%
3184465 261.1.1.0 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain 0.64 55.0 4.64e-01 95.7% 78.8%
3888566 261.1.1.0 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain 0.63 53.0 3.59e-01 93.5% 31.9%
4097842 2498.1.1.20 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M35 0.63 56.0 4.47e-01 98.9% 78.4%
4236605 2498.1.1.20 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M35 0.63 54.0 4.46e-01 94.6% 80.0%
3883178 261.1.1.0 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain 0.63 51.0 4.00e-01 88.2% 56.5%
5043168 2498.1.1.35 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M54 0.63 55.0 4.49e-01 95.7% 72.4%
4332917 2498.1.1.41 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M60 0.63 53.0 3.73e-01 93.5% 35.0%
4059019 2498.1.1.20 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M35 0.63 56.0 4.47e-01 100.0% 79.4%
3194591 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 54.0 4.18e-01 96.8% 94.4%
5044595 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.62 51.0 4.17e-01 92.5% 47.2%
5027975 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.61 44.0 4.45e-01 79.6% 74.7%
5051749 2005.1.1.14 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › PAPS_reduct 0.61 30.0 2.20e-01 87.1% 18.3%
3479503 2498.1.1.4 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Reprolysin 0.61 53.0 3.95e-01 94.6% 62.7%
5065597 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.59 48.0 4.01e-01 87.1% 56.2%
3716507 2498.5.1.0 mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like 0.55 35.0 3.30e-01 93.5% 53.0%
5010225 2003.1.3.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › DAO 0.54 44.0 3.02e-01 92.5% 94.2%
3596583 2003.1.2.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.53 44.0 2.91e-01 94.6% 87.6%
3238820 273.1.1.0 a+b three layers › PR-1-like › PR-1-like › PR-1-like 0.53 43.0 3.72e-01 89.2% 79.9%
None 0.53 44.0 3.41e-01 94.6% 96.9%
3966381 2003.1.3.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › DAO 0.53 44.0 2.96e-01 93.5% 90.5%
3368067 109.4.1.583 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DNA_pol_phi 0.51 43.0 2.94e-01 92.5% 45.8%
D3 medium residues 169-280
PDB
D4 medium residues 281-348
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vbiA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.59 43.0 3.16e-01 77.9% 87.0%
3wqcA02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.59 45.0 3.19e-01 83.8% 94.6%
3o3mB02 3.40.50.11890 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 42.0 3.51e-01 77.9% 100.0%
4dccA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.58 40.0 3.34e-01 73.5% 84.5%
2c31A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.57 41.0 3.08e-01 77.9% 86.2%
4qq8A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.57 41.0 3.07e-01 76.5% 87.4%
6ie0A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 39.0 3.15e-01 72.1% 72.4%
1ybhA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.56 40.0 2.98e-01 77.9% 80.0%
2i6xA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.55 38.0 3.16e-01 73.5% 80.6%
1kolA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 40.0 3.04e-01 77.9% 71.3%
5ahkA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.55 39.0 2.98e-01 77.9% 90.7%
5w56B02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.55 40.0 3.32e-01 79.4% 81.2%
1zczA01 3.40.50.1380 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylglyoxal synthase-like domain 0.54 40.0 3.17e-01 80.9% 78.2%
2ieeA02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.54 45.0 3.99e-01 92.6% 88.0%
4gmkA01 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 37.0 3.00e-01 73.5% 69.9%
3llvA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 39.0 3.30e-01 82.4% 97.0%
2panA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.53 38.0 2.96e-01 77.9% 90.0%
4p47A00 3.40.190.170 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 0.53 43.0 2.85e-01 92.6% 46.9%
3mfqA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.53 38.0 3.15e-01 79.4% 97.0%
7jj9A02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.53 36.0 3.10e-01 73.5% 88.3%
4n6dA00 3.40.190.170 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 0.53 45.0 2.92e-01 97.1% 45.1%
4kyqA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.52 43.0 3.07e-01 91.2% 85.0%
1zlpA00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.52 44.0 3.01e-01 100.0% 82.4%
4pfrA00 3.40.190.170 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 0.52 44.0 2.93e-01 97.1% 47.4%
1ii5A02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.51 42.0 3.86e-01 94.1% 93.5%
1pq4A02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.51 37.0 3.31e-01 79.4% 90.3%
1t6t200 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.51 39.0 3.40e-01 85.3% 87.3%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3950806 2007.1.14.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › ZnuA 0.63 46.0 3.81e-01 79.4% 82.3%
5030754 2007.1.10.6 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › PrpR receptor domain-like › Mut7-C 0.62 43.0 4.19e-01 72.1% 100.0%
3398461 2006.1.1.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.61 41.0 3.38e-01 70.6% 89.2%
4989338 2007.1.14.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.59 45.0 3.45e-01 83.8% 85.9%
4945521 2006.1.1.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_like 0.59 42.0 3.47e-01 75.0% 89.6%
3738162 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.58 42.0 3.11e-01 77.9% 84.7%
3973306 2007.1.14.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.58 45.0 3.86e-01 83.8% 86.4%
4989355 2006.1.3.6 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.58 42.0 3.60e-01 79.4% 76.7%
4942466 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.57 40.0 3.13e-01 75.0% 64.4%
5025617 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.57 41.0 3.03e-01 76.5% 65.1%
3931516 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.56 39.0 2.81e-01 73.5% 49.5%
3885465 2006.1.1.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.56 39.0 2.73e-01 72.1% 47.3%
4936315 2007.1.3.37 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Mut7-C 0.56 40.0 3.73e-01 77.9% 100.0%
3928151 2006.1.1.18 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.55 37.0 2.83e-01 72.1% 54.7%
5037065 2007.1.5.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.55 40.0 3.45e-01 80.9% 88.3%
3971358 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.55 39.0 2.97e-01 76.5% 87.2%
4972922 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.55 39.0 2.88e-01 76.5% 79.5%
2050622 2007.1.14.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › ZnuA 0.54 37.0 3.12e-01 73.5% 82.2%
3967455 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.54 38.0 2.93e-01 77.9% 88.9%
3386764 2007.1.14.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › ZnuA 0.53 37.0 3.20e-01 73.5% 81.7%
3686826 7512.1.1.10 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_28 0.53 37.0 2.84e-01 72.1% 84.9%
3899836 2006.1.1.41 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › 5-nucleotidase 0.52 39.0 3.08e-01 83.8% 98.7%
4023226 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.51 41.0 2.85e-01 89.7% 98.0%
4033486 2003.1.7.10 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › Rib_5-P_isom_A 0.51 39.0 3.10e-01 86.8% 86.7%
4649312 2007.1.14.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › ZnuA 0.51 36.0 3.11e-01 75.0% 82.6%
1518729 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.51 42.0 3.86e-01 94.1% 93.5%
1521775 7523.1.1.16 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › DctP 0.51 42.0 3.91e-01 92.6% 87.4%
3955326 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.50 36.0 2.80e-01 77.9% 92.2%
1523522 7523.1.1.16 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › DctP 0.50 40.0 3.75e-01 91.2% 87.8%