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IMGVR_UViG_3300039190_000305-3300039190-Ga0399989_003201_3_1937
Arc-VirIMGVR_UViG_3300039190_000305-3300039190-Ga0399989_003201_3_1937
Identity
- Kingdom:
- archaea
Quality
55.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 82-97_167-336
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2q2eB01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.72 | 66.0 | 6.22e-01 | 96.8% | 94.1% |
| 1mu5A01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.72 | 65.0 | 6.22e-01 | 96.2% | 99.5% |
| 1y4uB01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.71 | 64.0 | 6.36e-01 | 94.1% | 100.0% |
| 1pvgA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.71 | 67.0 | 6.04e-01 | 100.0% | 98.4% |
| 1b63A01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.71 | 66.0 | 6.22e-01 | 98.4% | 95.8% |
| 1aj6A00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.70 | 63.0 | 6.25e-01 | 95.2% | 100.0% |
| 2o1uB01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.69 | 58.0 | 6.21e-01 | 89.8% | 98.8% |
| 1h7sA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.65 | 59.0 | 5.84e-01 | 94.6% | 97.4% |
| 4a18P00 | 3.30.720.90 | Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › | 0.57 | 22.0 | 3.38e-01 | 84.4% | 92.4% |
| 1nijA02 | 3.30.1220.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Yjia; Chain: A;domain 2 › CobW-like, C-terminal domain | 0.56 | 33.0 | 4.02e-01 | 74.2% | 90.5% |
| 1k1gA00 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.52 | 30.0 | 3.59e-01 | 84.4% | 85.2% |
ECOD (84)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4927750 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.81 | 74.0 | 6.95e-01 | 94.6% | 94.4% |
| None | — | 0.80 | 68.0 | 6.38e-01 | 88.2% | 95.5% | |
| 3308932 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.79 | 73.0 | 6.61e-01 | 96.2% | 91.3% |
| 3656144 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.79 | 72.0 | 6.47e-01 | 94.6% | 91.3% |
| 5018927 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.79 | 72.0 | 6.91e-01 | 95.2% | 97.6% |
| 4029843 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.79 | 72.0 | 6.59e-01 | 95.2% | 95.7% |
| 3902919 | 225.1.1.2 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HSP90,HATPase_c_3 | 0.79 | 73.0 | 6.53e-01 | 96.2% | 87.3% |
| 3421099 | 225.1.1.2 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HSP90,HATPase_c_3 | 0.79 | 71.0 | 6.13e-01 | 93.0% | 93.2% |
| 4241931 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.78 | 69.0 | 6.48e-01 | 91.9% | 95.0% |
| None | — | 0.78 | 71.0 | 6.55e-01 | 95.2% | 96.5% | |
| None | — | 0.77 | 69.0 | 6.57e-01 | 91.9% | 95.7% | |
| None | — | 0.77 | 69.0 | 6.56e-01 | 91.9% | 95.7% | |
| 3495832 | 225.1.1.2 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HSP90,HATPase_c_3 | 0.77 | 64.0 | 6.72e-01 | 85.5% | 98.8% |
| 5027857 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.75 | 71.0 | 6.57e-01 | 98.9% | 96.9% |
| 4076203 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.75 | 69.0 | 6.15e-01 | 96.2% | 96.4% |
| 4928984 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.74 | 66.0 | 5.60e-01 | 94.1% | 86.2% |
| 3376998 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.74 | 69.0 | 5.85e-01 | 98.9% | 96.2% |
| 3721928 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.74 | 67.0 | 6.31e-01 | 94.6% | 88.4% |
| 3282394 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.73 | 67.0 | 6.32e-01 | 94.6% | 91.2% |
| 3923679 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.73 | 69.0 | 6.52e-01 | 98.9% | 97.7% |
| 3321967 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.73 | 69.0 | 6.45e-01 | 98.9% | 97.3% |
| 4504528 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.73 | 66.0 | 5.96e-01 | 93.5% | 94.6% |
| 3530518 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.73 | 67.0 | 6.53e-01 | 96.8% | 100.0% |
| 4969716 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.73 | 66.0 | 6.31e-01 | 94.6% | 100.0% |
| 4058338 | 225.1.1.2 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HSP90,HATPase_c_3 | 0.73 | 67.0 | 6.07e-01 | 96.2% | 97.5% |
| 3549359 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.73 | 67.0 | 6.18e-01 | 97.8% | 88.5% |
| 3729889 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.73 | 66.0 | 6.21e-01 | 95.7% | 94.5% |
| 3487863 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.73 | 66.0 | 5.72e-01 | 95.7% | 96.4% |
| 4930684 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.72 | 68.0 | 6.22e-01 | 100.0% | 95.8% |
| 5057421 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.72 | 69.0 | 6.56e-01 | 100.0% | 96.7% |
| 3694119 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.72 | 65.0 | 5.89e-01 | 94.1% | 90.4% |
| 4969341 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.72 | 67.0 | 6.22e-01 | 97.8% | 92.0% |
| 4259064 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.72 | 67.0 | 6.48e-01 | 98.4% | 98.5% |
| 3250443 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.72 | 66.0 | 6.08e-01 | 96.8% | 96.5% |
| 3632920 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.72 | 67.0 | 5.98e-01 | 98.9% | 89.6% |
| 4030281 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.72 | 67.0 | 6.05e-01 | 99.5% | 89.0% |
| 4221311 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.71 | 68.0 | 6.38e-01 | 100.0% | 93.6% |
| 3521361 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.71 | 65.0 | 5.61e-01 | 95.7% | 95.6% |
| 4969896 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.71 | 67.0 | 6.39e-01 | 98.4% | 96.2% |
| 4453541 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.71 | 67.0 | 6.38e-01 | 98.9% | 96.2% |
| 3196992 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.71 | 64.0 | 6.10e-01 | 94.6% | 90.7% |
| 3255595 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.71 | 65.0 | 6.22e-01 | 95.7% | 99.0% |
| 3799509 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.70 | 63.0 | 6.04e-01 | 94.1% | 91.4% |
| 3286344 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.70 | 62.0 | 5.77e-01 | 92.5% | 89.8% |
| 3169949 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.70 | 62.0 | 5.86e-01 | 94.6% | 97.7% |
| 3542858 | 225.1.1.13 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HSP90 | 0.69 | 65.0 | 6.04e-01 | 97.8% | 93.8% |
| 3784151 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.69 | 63.0 | 5.92e-01 | 96.2% | 92.3% |
| 5004468 | 225.1.1.19 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › SACS | 0.69 | 63.0 | 6.11e-01 | 94.6% | 94.5% |
| 3670213 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.68 | 63.0 | 5.87e-01 | 98.9% | 92.6% |
| 4273009 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.68 | 62.0 | 6.16e-01 | 95.2% | 99.5% |
| 4513602 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.67 | 60.0 | 5.96e-01 | 94.1% | 95.9% |
| 3838290 | 3585.1.1.0 ↗ | a+b two layers › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain | 0.62 | 19.0 | 3.12e-01 | 86.0% | 73.8% |
| 3943630 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.59 | 37.0 | 3.96e-01 | 71.5% | 71.2% |
| 3724686 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.59 | 37.0 | 3.89e-01 | 71.0% | 68.8% |
| 3982057 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.58 | 36.0 | 3.85e-01 | 84.4% | 69.7% |
| 4190082 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.56 | 35.0 | 3.81e-01 | 84.4% | 73.5% |
| 3254145 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.56 | 37.0 | 3.88e-01 | 85.5% | 70.9% |
| 3973083 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.56 | 36.0 | 3.79e-01 | 84.4% | 69.7% |
| 3257800 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.56 | 35.0 | 3.70e-01 | 70.4% | 68.8% |
| 3251562 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.53 | 38.0 | 3.90e-01 | 72.6% | 94.4% |
| 3743164 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.53 | 38.0 | 2.94e-01 | 73.7% | 57.7% |
| 3661715 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.53 | 38.0 | 3.86e-01 | 73.1% | 98.9% |
| 4015449 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.52 | 38.0 | 3.58e-01 | 73.7% | 90.9% |
| 3588903 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.52 | 37.0 | 4.02e-01 | 72.6% | 98.8% |
| 4152567 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.52 | 38.0 | 3.96e-01 | 74.2% | 96.0% |
| 4022754 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.52 | 38.0 | 3.91e-01 | 74.7% | 97.8% |
| 3969045 | 3585.1.1.1 ↗ | a+b two layers › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain › DNA_pol_IIIA_C | 0.52 | 25.0 | 3.50e-01 | 76.9% | 98.8% |
| 5035233 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.52 | 36.0 | 3.88e-01 | 70.4% | 98.1% |
| 4034483 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.52 | 37.0 | 3.89e-01 | 72.0% | 98.2% |
| 4644950 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.52 | 37.0 | 3.94e-01 | 73.1% | 98.8% |
| 4929437 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.52 | 37.0 | 3.84e-01 | 72.6% | 99.4% |
| 4951560 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 37.0 | 4.00e-01 | 72.6% | 100.0% |
| 5002295 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 37.0 | 3.85e-01 | 74.2% | 90.9% |
| 3988378 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 36.0 | 3.91e-01 | 72.6% | 98.8% |
| 4412887 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 37.0 | 3.97e-01 | 73.7% | 100.0% |
| 5019278 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 36.0 | 3.83e-01 | 72.0% | 95.2% |
| 3279076 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 37.0 | 3.85e-01 | 74.2% | 93.7% |
| 4254876 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 36.0 | 3.90e-01 | 72.6% | 93.8% |
| 4054483 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 36.0 | 3.90e-01 | 72.6% | 99.4% |
| 4056470 | 3585.1.1.1 ↗ | a+b two layers › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain › DNA_pol_IIIA_C | 0.51 | 25.0 | 3.40e-01 | 76.3% | 100.0% |
| 4655477 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 36.0 | 3.77e-01 | 72.0% | 94.1% |
| 3990103 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.50 | 36.0 | 3.74e-01 | 72.0% | 93.5% |
| 3945353 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.50 | 36.0 | 3.86e-01 | 73.7% | 95.2% |
| 5061039 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.50 | 35.0 | 3.83e-01 | 72.0% | 98.1% |
D2
medium
residues 98-166
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1neiA00 | 3.30.160.220 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG | 0.69 | 35.0 | 3.75e-01 | 95.7% | 56.7% |
| 3r0aA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 44.0 | 3.65e-01 | 72.5% | 76.7% |
| 2rh3A00 | 1.10.1220.190 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant › VirC2, RHH domain | 0.58 | 48.0 | 4.04e-01 | 94.2% | 81.8% |
| 2vfkA00 | 3.90.1140.10 | Alpha Beta › Alpha-Beta Complex › Cyclic Phosphodiesterase; Chain: A, › Cyclic phosphodiesterase | 0.57 | 42.0 | 3.07e-01 | 79.7% | 61.0% |
| 2rkvA01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.57 | 48.0 | 3.44e-01 | 94.2% | 79.4% |
| 3caiA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.57 | 50.0 | 3.95e-01 | 97.1% | 75.5% |
| 4abyD00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 49.0 | 3.21e-01 | 100.0% | 23.8% |
| 3h95A02 | 4.10.80.100 | Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › | 0.55 | 26.0 | 3.22e-01 | 73.9% | 86.7% |
| 4jz6A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 41.0 | 2.77e-01 | 78.3% | 62.8% |
| 2oarB00 | 1.10.1200.120 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Large-conductance mechanosensitive channel, MscL; domain 1 | 0.55 | 47.0 | 3.97e-01 | 100.0% | 56.8% |
| 3ly1D01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 44.0 | 3.73e-01 | 97.1% | 94.6% |
| 1vdhA01 | 3.30.70.1030 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1 | 0.54 | 44.0 | 3.61e-01 | 100.0% | 50.4% |
| 2nyxB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 44.0 | 3.65e-01 | 100.0% | 82.4% |
| 1auwA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.53 | 47.0 | 3.24e-01 | 97.1% | 51.3% |
| 1fxkB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 42.0 | 3.50e-01 | 84.1% | 71.6% |
| 4mtnA01 | 3.30.1480.10 | Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain | 0.52 | 45.0 | 4.02e-01 | 94.2% | 69.5% |
| 1zcdA00 | 1.20.1530.10 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain | 0.52 | 46.0 | 2.88e-01 | 100.0% | 51.9% |
| 2k3iA01 | 3.30.70.860 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 42.0 | 3.92e-01 | 89.9% | 77.6% |
| 6ahuH01 | 3.30.70.3250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribonuclease P, Pop5 subunit | 0.51 | 40.0 | 3.61e-01 | 85.5% | 71.6% |
| 1kfiA04 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.51 | 41.0 | 3.46e-01 | 92.8% | 84.0% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3637098 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.86 | 45.0 | 3.51e-01 | 78.3% | 27.1% |
| 3472968 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.77 | 46.0 | 2.75e-01 | 84.1% | 9.2% |
| 3208120 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.77 | 45.0 | 3.40e-01 | 81.2% | 26.5% |
| 4999286 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.71 | 41.0 | 3.00e-01 | 81.2% | 22.2% |
| 3520689 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.70 | 46.0 | 2.94e-01 | 88.4% | 15.3% |
| 3824122 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.68 | 49.0 | 3.04e-01 | 75.4% | 20.9% |
| 3791945 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.67 | 42.0 | 2.89e-01 | 81.2% | 19.6% |
| 4645961 | 102.2.1.3 ↗ | alpha arrays › HhH/H2TH › H2TH › H2TH › NFACT_N | 0.67 | 41.0 | 2.99e-01 | 81.2% | 22.6% |
| 4937951 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.67 | 50.0 | 4.39e-01 | 78.3% | 92.0% |
| 3260131 | 109.4.1.414 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MMS19_N | 0.67 | 39.0 | 2.55e-01 | 76.8% | 13.9% |
| 3960425 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.63 | 54.0 | 4.40e-01 | 95.7% | 78.9% |
| 5000789 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.61 | 40.0 | 3.47e-01 | 75.4% | 43.8% |
| 4453177 | 4207.1.2.1 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › Med7 | 0.61 | 43.0 | 3.59e-01 | 81.2% | 41.6% |
| 4004118 | 375.1.1.179 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha | 0.61 | 48.0 | 3.55e-01 | 87.0% | 95.7% |
| 3056876 | 167.1.1.0 ↗ | alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 | 0.61 | 41.0 | 3.51e-01 | 95.7% | 43.8% |
| 2979134 | 167.1.1.1 ↗ | alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 | 0.61 | 41.0 | 3.51e-01 | 95.7% | 43.8% |
| 5065027 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.59 | 38.0 | 2.98e-01 | 75.4% | 30.3% |
| 3605494 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.58 | 45.0 | 3.74e-01 | 81.2% | 53.0% |
| 2391543 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.57 | 44.0 | 3.11e-01 | 81.2% | 29.4% |
| 5016748 | 101.1.2.30 ↗ | alpha arrays › HTH › HTH › winged helix domain › TrmB | 0.57 | 45.0 | 3.86e-01 | 89.9% | 80.0% |
| 3442291 | 2.9.1.1 ↗ | beta barrels › OB-fold › RNB domain-like › RNB domain-like › RNB | 0.56 | 50.0 | 3.02e-01 | 98.6% | 48.3% |
| 4381440 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.56 | 43.0 | 3.59e-01 | 81.2% | 73.9% |
| 3306699 | 101.1.2.517 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD | 0.56 | 50.0 | 3.13e-01 | 100.0% | 54.1% |
| 4297859 | 314.1.1.2 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b | 0.56 | 49.0 | 3.20e-01 | 98.6% | 53.7% |
| 3589192 | 101.1.1.68 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_38 | 0.56 | 40.0 | 3.87e-01 | 89.9% | 67.5% |
| 3734132 | 3542.1.1.3 ↗ | alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Peptidase_A22B | 0.56 | 45.0 | 3.00e-01 | 92.8% | 89.5% |
| 3488760 | 3937.1.1.0 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 | 0.56 | 42.0 | 2.75e-01 | 81.2% | 22.6% |
| 4349140 | 323.1.1.12 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › TRI-like_N | 0.55 | 45.0 | 3.35e-01 | 92.8% | 69.2% |
| 3649913 | 5050.1.1.58 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NFD4_C | 0.55 | 45.0 | 3.33e-01 | 88.4% | 37.1% |
| 4112182 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.55 | 42.0 | 3.50e-01 | 82.6% | 72.0% |
| 3504218 | 377.1.1.10 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › ArfGap | 0.54 | 41.0 | 2.54e-01 | 82.6% | 14.0% |
| 5042930 | 3563.1.1.1 ↗ | alpha bundles › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › TatC | 0.54 | 41.0 | 2.81e-01 | 82.6% | 59.3% |
| 5062171 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.54 | 46.0 | 3.55e-01 | 94.2% | 56.7% |
| 3640260 | 101.1.2.31 ↗ | alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha | 0.53 | 41.0 | 3.03e-01 | 87.0% | 87.8% |
| 4516798 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.53 | 42.0 | 2.57e-01 | 84.1% | 26.6% |
| 4071235 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.53 | 42.0 | 2.53e-01 | 84.1% | 24.0% |
| 3215753 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.52 | 48.0 | 2.85e-01 | 100.0% | 25.3% |
| 4009252 | 3371.1.1.2 ↗ | few secondary structure elements › Regulator of transcription protein Rtr1 › Regulator of transcription protein Rtr1 › Regulator of transcription protein Rtr1 › PF27493 | 0.52 | 33.0 | 3.74e-01 | 81.2% | 90.0% |
| 3883105 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.52 | 48.0 | 2.82e-01 | 100.0% | 59.4% |
| 3499881 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.52 | 47.0 | 2.93e-01 | 98.6% | 31.5% |
| 4183868 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.52 | 43.0 | 4.15e-01 | 91.3% | 82.3% |
| 5011884 | 3563.1.1.1 ↗ | alpha bundles › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › TatC | 0.52 | 44.0 | 3.04e-01 | 100.0% | 47.3% |
| 3880785 | 3937.1.1.1 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Connexin | 0.51 | 46.0 | 3.30e-01 | 100.0% | 71.0% |
| 3885537 | 327.16.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system | 0.51 | 38.0 | 3.75e-01 | 85.5% | 73.3% |
| 3357805 | 3887.2.1.1 ↗ | a+b two layers › Yeast killer toxin-like › Antifungal protein ginkbilobin-2 › Antifungal protein ginkbilobin-2 › Stress-antifung | 0.51 | 37.0 | 3.62e-01 | 76.8% | 85.3% |
| 5073431 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.51 | 44.0 | 2.65e-01 | 98.6% | 40.0% |
| 3702909 | 6166.1.1.1 ↗ | alpha bundles › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › ERG4_ERG24 | 0.50 | 44.0 | 3.15e-01 | 100.0% | 70.9% |
| 4981961 | 101.1.2.819 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF27231 | 0.50 | 39.0 | 2.99e-01 | 84.1% | 82.5% |
| 3234976 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.50 | 42.0 | 3.52e-01 | 88.4% | 67.3% |
| 3593545 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.50 | 42.0 | 2.87e-01 | 95.7% | 42.5% |
D3
medium
residues 337-360_412-443
D4
medium
residues 573-645