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IMGVR_UViG_3300040735_000066-3300040735-Ga0439195_003925_3483_4691
Arc-VirIMGVR_UViG_3300040735_000066-3300040735-Ga0439195_003925_3483_4691
Identity
- Kingdom:
- archaea
Quality
86.8
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 13-65
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4i9fA03 | 3.30.300.290 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.58 | 44.0 | 4.05e-01 | 100.0% | 61.0% |
| 3cb2A02 | 3.30.1330.20 | Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Tubulin/FtsZ, C-terminal domain | 0.51 | 36.0 | 3.09e-01 | 92.5% | 42.4% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5019938 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.96 | 90.0 | 5.66e-01 | 100.0% | 23.5% |
| 5025630 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.63 | 53.0 | 3.80e-01 | 92.5% | 38.6% |
| 3229785 | 2007.1.2.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor | 0.54 | 39.0 | 2.65e-01 | 96.2% | 17.6% |
| 3180655 | 7502.1.1.1 ↗ | a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › HGTP_anticodon | 0.54 | 43.0 | 3.15e-01 | 90.6% | 37.3% |
| 5009868 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.52 | 42.0 | 3.49e-01 | 94.3% | 56.0% |
| 3700204 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.50 | 37.0 | 2.20e-01 | 84.9% | 9.0% |
D2
high
residues 82-195
Domain cluster:
representative
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.70 | 47.0 | 5.03e-01 | 88.6% | 79.0% |
| 7utzR02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 52.0 | 3.99e-01 | 89.5% | 97.1% |
| 4oe8C00 | 1.10.8.1170 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.63 | 43.0 | 4.74e-01 | 84.2% | 90.8% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.62 | 31.0 | 3.61e-01 | 75.4% | 65.4% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.62 | 56.0 | 4.84e-01 | 100.0% | 89.8% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.61 | 54.0 | 4.52e-01 | 96.5% | 69.6% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 53.0 | 4.90e-01 | 96.5% | 99.3% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 44.0 | 4.53e-01 | 88.6% | 81.3% |
| 6vmsR00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 49.0 | 3.73e-01 | 88.6% | 95.7% |
| 2ptqA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.60 | 48.0 | 3.61e-01 | 86.0% | 81.3% |
| 3jrtA00 | 1.20.120.1060 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 53.0 | 4.75e-01 | 100.0% | 88.6% |
| 7um4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 48.0 | 3.77e-01 | 87.7% | 87.6% |
| 4xt1A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 48.0 | 3.66e-01 | 88.6% | 90.4% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 47.0 | 3.70e-01 | 87.7% | 98.1% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 44.0 | 4.19e-01 | 90.4% | 65.9% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.59 | 48.0 | 4.42e-01 | 87.7% | 77.7% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 45.0 | 4.49e-01 | 87.7% | 77.9% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 49.0 | 3.84e-01 | 95.6% | 78.2% |
| 4dhiB02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.58 | 46.0 | 4.32e-01 | 94.7% | 67.6% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 49.0 | 4.82e-01 | 93.0% | 96.8% |
| 7ys6A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 47.0 | 3.64e-01 | 88.6% | 99.6% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 35.0 | 4.16e-01 | 72.8% | 89.5% |
| 3fajA00 | 1.20.120.950 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 | 0.58 | 47.0 | 4.92e-01 | 96.5% | 98.0% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.58 | 50.0 | 5.00e-01 | 95.6% | 96.6% |
| 4hyjA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 49.0 | 3.97e-01 | 95.6% | 83.1% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.58 | 39.0 | 4.39e-01 | 78.1% | 91.8% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 50.0 | 4.82e-01 | 95.6% | 91.4% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.57 | 48.0 | 4.36e-01 | 91.2% | 78.8% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 45.0 | 4.17e-01 | 89.5% | 67.6% |
| 5hyhA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.56 | 45.0 | 3.42e-01 | 88.6% | 54.4% |
| 2r9rH02 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.55 | 47.0 | 4.35e-01 | 95.6% | 84.9% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 39.0 | 4.11e-01 | 82.5% | 83.5% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 44.0 | 3.38e-01 | 89.5% | 92.6% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 41.0 | 3.37e-01 | 82.5% | 82.7% |
| 7e4gA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 44.0 | 3.67e-01 | 87.7% | 99.5% |
| 4l6rA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 45.0 | 3.41e-01 | 93.0% | 69.9% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 46.0 | 4.50e-01 | 99.1% | 93.8% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.53 | 44.0 | 4.10e-01 | 95.6% | 85.0% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.52 | 44.0 | 3.77e-01 | 93.0% | 77.6% |
| 3whjA00 | 6.10.140.1710 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 37.0 | 3.76e-01 | 72.8% | 83.8% |
| 1t33A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 43.0 | 3.91e-01 | 91.2% | 86.1% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 43.0 | 3.53e-01 | 90.4% | 59.4% |
| 5tj5E00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.51 | 40.0 | 3.79e-01 | 86.0% | 71.0% |
| 3i44A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.51 | 44.0 | 3.36e-01 | 98.2% | 64.2% |
ECOD (56)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4371240 | 632.7.1.55 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF2605 | 0.64 | 47.0 | 5.10e-01 | 90.4% | 91.6% |
| 4675868 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.63 | 52.0 | 3.91e-01 | 89.5% | 91.6% |
| 4990419 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.63 | 57.0 | 5.08e-01 | 99.1% | 98.1% |
| 4634281 | 611.4.1.0 ↗ | alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like | 0.63 | 48.0 | 4.41e-01 | 89.5% | 61.3% |
| 5035899 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.63 | 57.0 | 5.06e-01 | 100.0% | 98.1% |
| 5075639 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.62 | 49.0 | 4.61e-01 | 87.7% | 69.6% |
| 3453285 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.62 | 46.0 | 4.36e-01 | 84.2% | 65.9% |
| 4995193 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.61 | 55.0 | 5.04e-01 | 99.1% | 100.0% |
| 3227678 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.61 | 44.0 | 4.67e-01 | 88.6% | 86.0% |
| 3783128 | 5001.1.1.28 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Per1 | 0.61 | 54.0 | 4.16e-01 | 99.1% | 82.6% |
| 3599199 | 601.30.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 | 0.61 | 54.0 | 4.89e-01 | 100.0% | 96.1% |
| 3713371 | 5054.1.1.9 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PKD_channel | 0.60 | 51.0 | 3.58e-01 | 92.1% | 44.4% |
| 2396196 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.60 | 53.0 | 5.04e-01 | 95.6% | 94.7% |
| 3783621 | 4177.1.1.14 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_2 | 0.60 | 50.0 | 3.66e-01 | 89.5% | 74.9% |
| 4934608 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.59 | 51.0 | 4.83e-01 | 95.6% | 87.1% |
| 4315686 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.59 | 48.0 | 3.51e-01 | 89.5% | 84.9% |
| 4025051 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.59 | 53.0 | 4.87e-01 | 100.0% | 95.3% |
| 3448339 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.59 | 48.0 | 4.45e-01 | 87.7% | 71.0% |
| 3911774 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.59 | 50.0 | 3.64e-01 | 93.0% | 77.5% |
| 5068068 | 601.30.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 | 0.59 | 52.0 | 4.98e-01 | 99.1% | 97.0% |
| 5075398 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.58 | 51.0 | 4.61e-01 | 100.0% | 90.3% |
| 4561197 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.58 | 49.0 | 4.09e-01 | 93.0% | 73.7% |
| 3663674 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.58 | 48.0 | 4.32e-01 | 91.2% | 89.1% |
| 4003831 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.58 | 49.0 | 3.59e-01 | 93.0% | 75.6% |
| 3437243 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.58 | 49.0 | 4.64e-01 | 91.2% | 91.9% |
| 3705837 | 192.12.1.5 ↗ | alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM › Cmc1 | 0.57 | 35.0 | 3.87e-01 | 100.0% | 78.8% |
| 4857797 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.57 | 41.0 | 3.41e-01 | 74.6% | 46.3% |
| 4023355 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.57 | 47.0 | 3.56e-01 | 89.5% | 79.6% |
| 3255555 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.57 | 49.0 | 4.19e-01 | 96.5% | 62.6% |
| 3558619 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.56 | 46.0 | 3.34e-01 | 89.5% | 85.0% |
| 3879591 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.56 | 46.0 | 3.38e-01 | 89.5% | 89.5% |
| 3236426 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.56 | 50.0 | 3.60e-01 | 99.1% | 76.2% |
| 3347110 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.56 | 47.0 | 3.74e-01 | 93.0% | 63.4% |
| 3249529 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.56 | 48.0 | 4.62e-01 | 96.5% | 92.6% |
| 3676218 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 49.0 | 4.24e-01 | 99.1% | 79.5% |
| 3934569 | 633.6.1.12 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX+ACOX_C_alpha1 | 0.56 | 45.0 | 3.20e-01 | 89.5% | 86.7% |
| 3862609 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.55 | 47.0 | 4.50e-01 | 93.0% | 93.8% |
| 3430437 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.55 | 46.0 | 3.73e-01 | 95.6% | 61.6% |
| 4983442 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.55 | 32.0 | 3.49e-01 | 71.9% | 67.4% |
| 3785875 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.54 | 38.0 | 2.89e-01 | 72.8% | 98.9% |
| 3650966 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.54 | 48.0 | 3.85e-01 | 100.0% | 57.8% |
| 3736616 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.53 | 39.0 | 2.84e-01 | 77.2% | 29.7% |
| None | — | 0.53 | 46.0 | 3.50e-01 | 99.1% | 38.6% | |
| 3176740 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 44.0 | 3.56e-01 | 89.5% | 73.5% |
| 5073361 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.53 | 42.0 | 3.58e-01 | 87.7% | 67.0% |
| 3690688 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 43.0 | 3.59e-01 | 87.7% | 61.5% |
| 3607777 | 5050.1.1.23 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › CLN3 | 0.52 | 44.0 | 3.62e-01 | 93.0% | 58.1% |
| 5063996 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.52 | 37.0 | 2.95e-01 | 71.9% | 38.2% |
| 4666952 | 2007.1.18.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) | 0.52 | 46.0 | 3.52e-01 | 100.0% | 90.0% |
| 3323160 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 47.0 | 3.67e-01 | 100.0% | 54.5% |
| 3263028 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.52 | 46.0 | 3.77e-01 | 100.0% | 60.0% |
| 3688308 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 44.0 | 3.59e-01 | 93.0% | 58.6% |
| 4960297 | 604.6.1.67 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF5788 | 0.51 | 35.0 | 3.64e-01 | 72.8% | 73.6% |
| 3480875 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 43.0 | 3.40e-01 | 93.0% | 51.0% |
| 3722869 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.50 | 43.0 | 3.09e-01 | 100.0% | 60.7% |
| 4063704 | 5050.1.1.14 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › ATG22 | 0.50 | 42.0 | 3.52e-01 | 95.6% | 57.7% |
D3
medium
residues 215-310
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF08463.16 best | EcoEI_R_C | 57.2 | 3.00e-15 | 92.7% | 43.2% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2wbiA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 46.0 | 4.30e-01 | 88.5% | 97.5% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 39.0 | 3.39e-01 | 76.0% | 98.7% |
| 2q00B00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.53 | 39.0 | 3.65e-01 | 77.1% | 62.3% |
| 7wf8B01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.53 | 38.0 | 3.58e-01 | 92.7% | 60.3% |
| 5ulcX00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.53 | 38.0 | 3.54e-01 | 76.0% | 95.1% |
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.52 | 34.0 | 3.64e-01 | 89.6% | 74.4% |
| 3u66A00 | 1.25.40.590 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU | 0.52 | 39.0 | 3.27e-01 | 90.6% | 45.2% |
| 6wy9B01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.51 | 42.0 | 4.00e-01 | 92.7% | 100.0% |
| 3hn2A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.51 | 39.0 | 3.55e-01 | 97.9% | 60.9% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.51 | 40.0 | 4.02e-01 | 96.9% | 85.6% |
| 1x42A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.51 | 35.0 | 3.71e-01 | 94.8% | 81.9% |
| 5cqgA03 | 1.10.10.2210 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.51 | 32.0 | 3.46e-01 | 97.9% | 77.2% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4567935 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.61 | 38.0 | 4.42e-01 | 94.8% | 92.3% |
| 3743820 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.58 | 33.0 | 3.20e-01 | 77.1% | 47.3% |
| 3236724 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.57 | 39.0 | 3.88e-01 | 100.0% | 65.7% |
| 3230324 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.55 | 40.0 | 3.75e-01 | 76.0% | 94.2% |
| 3944006 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.54 | 35.0 | 3.18e-01 | 76.0% | 48.8% |
| 3854689 | 110.1.1.0 ↗ | alpha arrays › DEATH domain › DEATH domain › DEATH domain | 0.53 | 31.0 | 3.52e-01 | 86.5% | 78.6% |
| 3510771 | 610.4.1.0 ↗ | alpha arrays › ERP29 C domain-like › YqeY domain › YqeY domain | 0.51 | 39.0 | 3.88e-01 | 82.3% | 93.0% |
| 4927086 | 6049.1.1.3 ↗ | alpha bundles › PH0832-like › PH0832-like › PH0832-like › NitrOD2 | 0.50 | 39.0 | 3.92e-01 | 88.5% | 85.3% |
| 4390743 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.50 | 39.0 | 3.38e-01 | 96.9% | 50.3% |
D4
medium
residues 319-401
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF08463.16 best | EcoEI_R_C | 73.8 | 2.40e-20 | 100.0% | 48.8% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3safA02 | 1.10.150.80 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain | 0.65 | 50.0 | 4.76e-01 | 100.0% | 70.0% |
| 4nlbA02 | 1.10.150.80 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain | 0.61 | 51.0 | 4.90e-01 | 100.0% | 81.9% |
| 1sv0D00 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.58 | 43.0 | 4.34e-01 | 100.0% | 82.7% |
| 4rflA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.55 | 46.0 | 3.65e-01 | 100.0% | 79.9% |
| 3onqA03 | 1.10.10.2840 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain | 0.55 | 43.0 | 3.81e-01 | 88.0% | 58.0% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.54 | 38.0 | 3.79e-01 | 72.3% | 71.8% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 38.0 | 3.44e-01 | 74.7% | 83.9% |
| 7s0rB01 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.50 | 36.0 | 3.78e-01 | 94.0% | 82.9% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5019939 | 101.1.1.381 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › EcoEI_R_C | 0.99 | 93.0 | 9.52e-01 | 96.4% | 100.0% |
| 4964244 | 101.1.10.81 ↗ | alpha arrays › HTH › HTH › Cyclin-like › EcoEI_R_C | 0.94 | 85.0 | 8.72e-01 | 97.6% | 97.5% |
| 5018561 | 101.1.1.381 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › EcoEI_R_C | 0.89 | 80.0 | 8.08e-01 | 100.0% | 95.2% |
| 4010426 | 1079.1.1.13 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Mntp | 0.56 | 51.0 | 3.91e-01 | 100.0% | 58.9% |
| 5047069 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.56 | 44.0 | 3.21e-01 | 84.3% | 40.0% |
| 5021068 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.54 | 40.0 | 3.93e-01 | 79.5% | 83.3% |
| 3587728 | 162.1.1.0 ↗ | alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD | 0.52 | 42.0 | 3.67e-01 | 100.0% | 59.2% |
| 4397211 | 162.1.1.1 ↗ | alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PRD | 0.51 | 43.0 | 4.05e-01 | 96.4% | 80.0% |
| 3989535 | 632.6.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit | 0.51 | 40.0 | 3.87e-01 | 98.8% | 73.7% |
| 4945326 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.51 | 36.0 | 3.68e-01 | 97.6% | 76.2% |