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IMGVR_UViG_3300040944_000149-3300040944-Ga0439237_0022153_1045_3702

Arc-Vir

IMGVR_UViG_3300040944_000149-3300040944-Ga0439237_0022153_1045_3702

Quality

80.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-142
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF09250.17 best Prim-Pol 104.9 8.30e-30 96.3% 82.3%
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2atzA00 3.90.920.20 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › HP0184-like 0.58 49.0 4.52e-01 92.6% 93.2%
4i68A00 3.30.70.1800 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 35.0 4.04e-01 70.4% 91.1%
3otdA00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.55 39.0 3.27e-01 72.6% 92.1%
4ch7A02 3.30.70.3460 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 41.0 3.75e-01 79.3% 97.3%
3lwsF02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 30.0 3.32e-01 83.0% 67.3%
1wvqA00 3.40.1520.10 Alpha Beta › 3-Layer(aba) Sandwich › hypothetical protein tt1634 › Ta1353-like 0.53 37.0 3.52e-01 71.9% 77.9%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3280020 862.1.1.3 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › Prim-Pol 0.86 82.0 7.38e-01 100.0% 80.0%
4960053 862.1.1.3 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › Prim-Pol 0.82 74.0 6.54e-01 94.8% 90.8%
4940784 862.1.1.3 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › Prim-Pol 0.78 69.0 6.59e-01 100.0% 81.3%
4959587 862.1.1.3 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › Prim-Pol 0.77 73.0 6.69e-01 100.0% 80.6%
4962598 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.68 60.0 5.49e-01 100.0% 74.7%
3182862 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.55 38.0 4.36e-01 72.6% 95.0%
159378 304.105.1.1 a+b two layers › Alpha-beta plaits › Hypothetical protein Ta1353 › Hypothetical protein Ta1353 › Adenosine_kin 0.53 37.0 3.52e-01 71.9% 77.9%
3474429 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.52 36.0 3.96e-01 71.1% 90.9%
3648085 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.52 32.0 3.83e-01 74.1% 96.5%
4982756 304.102.1.2 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruD 0.51 36.0 3.25e-01 71.9% 87.4%
3224917 304.9.1.18 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Tap-RNA_bind 0.51 32.0 3.82e-01 87.4% 100.0%
3897640 304.9.1.18 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Tap-RNA_bind 0.51 32.0 3.84e-01 70.4% 95.6%
3669756 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.51 32.0 3.77e-01 77.0% 97.6%
5075438 304.4.1.29 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg_3 0.51 30.0 3.60e-01 70.4% 91.8%
4950375 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.50 30.0 3.54e-01 70.4% 89.8%
3931525 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.50 38.0 3.89e-01 91.1% 84.6%
3619277 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.50 31.0 3.64e-01 77.8% 92.2%
D2 high residues 169-258
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01807.26 best Zn_ribbon_DnaG 31.1 2.30e-07 88.9% 64.3%
D3 high residues 405-672
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF19263.6 best DUF5906 30.6 6.40e-07 44.8% 99.1%
PF08706.17 D5_N 39.4 1.00e-09 19.0% 34.0%
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1tueD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.79 59.0 6.72e-01 90.7% 100.0%
1u0jA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.76 57.0 6.42e-01 97.0% 99.5%
1r6bX04 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 48.0 5.56e-01 73.9% 100.0%
3nbxX01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 50.0 5.57e-01 88.1% 99.5%
3ja8204 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 56.0 5.16e-01 98.5% 95.9%
1g41A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 43.0 4.98e-01 76.1% 100.0%
4r7zA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 54.0 5.07e-01 98.1% 100.0%
3f8tA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 53.0 5.22e-01 97.4% 100.0%
2cvhA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 39.0 4.31e-01 81.3% 93.0%
3g68A02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.51 29.0 3.77e-01 70.9% 98.6%
4wiaC00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 39.0 4.19e-01 97.0% 92.9%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4973289 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.97 92.0 9.33e-01 99.6% 97.4%
3954608 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.96 90.0 9.13e-01 100.0% 97.3%
4959586 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.93 83.0 8.23e-01 100.0% 87.8%
5081314 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.92 84.0 8.53e-01 100.0% 96.5%
5029777 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.91 83.0 8.59e-01 100.0% 98.8%
5003620 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.91 81.0 7.43e-01 100.0% 73.7%
5022020 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.90 86.0 8.66e-01 100.0% 98.9%
5035042 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.88 85.0 8.48e-01 100.0% 98.2%
3945876 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.85 79.0 8.03e-01 100.0% 97.4%
2810781 8001.1.1.1 alpha arrays › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › PPV_E1_C 0.80 59.0 6.44e-01 89.9% 90.5%
5011495 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.79 55.0 6.32e-01 89.9% 94.0%
9753 2004.1.1.48 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PPV_E1_C 0.78 57.0 6.55e-01 89.9% 98.5%
4926850 2004.1.1.22 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sigma54_activat 0.76 45.0 5.82e-01 78.0% 100.0%
4998586 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.75 47.0 5.30e-01 83.2% 79.0%
4033843 2004.1.1.313 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › VapE-like_dom 0.75 54.0 6.24e-01 88.8% 99.5%
5058121 2004.1.1.1224 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF31144 0.75 71.0 6.85e-01 100.0% 96.0%
3254493 2004.1.1.153 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_2 0.71 51.0 5.21e-01 72.0% 96.2%
4314819 2004.1.1.58 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase 0.70 50.0 5.81e-01 76.1% 99.0%
5013281 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.68 63.0 6.15e-01 97.0% 99.6%
3839744 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 53.0 5.39e-01 81.3% 90.2%
3665498 2004.1.1.153 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_2 0.65 49.0 4.79e-01 76.9% 100.0%
4090171 2004.1.1.424 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase, AAA_2, AAA_5 0.65 49.0 4.95e-01 76.5% 97.4%
5034518 2004.1.1.46 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM 0.65 51.0 5.64e-01 85.1% 100.0%
3952423 2004.1.1.339 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF3631 0.64 57.0 5.79e-01 93.3% 97.0%
4542391 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 44.0 4.57e-01 84.3% 73.6%
3212870 2004.1.1.154 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_2,AAA_5 0.64 46.0 4.39e-01 73.5% 100.0%
4443044 2004.1.1.1014 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF27228 0.64 59.0 5.64e-01 98.5% 100.0%
None 0.64 50.0 5.46e-01 87.7% 100.0%
4271043 2004.1.1.223 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › bpMoxR 0.63 50.0 5.46e-01 87.7% 100.0%
4030223 2004.1.1.418 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM, Mg_chelatase 0.63 52.0 5.19e-01 85.1% 100.0%
5010380 2004.1.1.1014 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF27228 0.63 58.0 5.45e-01 98.5% 98.4%
4218663 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 42.0 4.74e-01 82.8% 87.8%
None 0.62 58.0 4.73e-01 99.6% 80.0%
3601515 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 37.0 3.86e-01 84.3% 61.6%
4992064 2004.1.1.223 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › bpMoxR 0.62 55.0 5.38e-01 94.8% 96.6%
3677397 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 57.0 4.58e-01 98.1% 75.7%
None 0.62 57.0 4.90e-01 98.1% 92.9%
3465917 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 57.0 4.64e-01 98.1% 79.4%
None 0.62 57.0 4.72e-01 98.1% 78.9%
3963614 2004.1.1.58 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase 0.62 51.0 5.11e-01 85.8% 96.7%
3695173 2004.1.1.46 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM 0.61 54.0 5.19e-01 91.8% 99.7%
3197159 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 51.0 4.33e-01 86.2% 66.7%
4974815 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 42.0 4.89e-01 74.6% 95.4%
5012900 2004.1.1.46 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM 0.61 50.0 5.31e-01 85.4% 100.0%
4017535 2004.1.1.418 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM, Mg_chelatase 0.61 53.0 4.99e-01 91.0% 100.0%
3703312 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 56.0 4.93e-01 99.6% 89.1%
5003899 2004.1.1.46 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM 0.60 52.0 5.20e-01 91.0% 100.0%
3255516 2004.1.1.46 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM 0.60 52.0 5.09e-01 89.6% 100.0%
None 0.60 52.0 5.22e-01 90.3% 100.0%
3594046 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 47.0 4.81e-01 80.2% 94.2%
3481498 2004.1.1.418 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM, Mg_chelatase 0.60 52.0 5.13e-01 91.0% 99.6%
3476274 2004.1.1.418 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM, Mg_chelatase 0.59 51.0 5.12e-01 90.3% 100.0%
3594982 2004.1.1.46 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM 0.59 49.0 4.96e-01 85.1% 100.0%
3611910 2004.1.1.418 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM, Mg_chelatase 0.59 52.0 5.18e-01 92.5% 100.0%
3281544 2004.1.1.584 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sigma54_activat, Mg_chelatase 0.58 48.0 5.05e-01 85.8% 98.8%
3590003 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.58 44.0 4.54e-01 76.1% 99.2%
4013468 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 47.0 4.74e-01 85.4% 100.0%
4519472 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 26.0 3.48e-01 82.8% 84.8%
D4 high residues 822-884
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2e8gA01 1.20.1440.150 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.68 50.0 4.04e-01 79.4% 70.2%
6wv5A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.66 48.0 3.81e-01 79.4% 64.7%
1e6bA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 52.0 4.29e-01 85.7% 84.7%
1y7oB00 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.65 57.0 4.10e-01 96.8% 47.8%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.64 47.0 3.42e-01 100.0% 29.0%
3s64A00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.61 53.0 4.95e-01 100.0% 95.1%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.60 44.0 4.05e-01 81.0% 83.0%
4hbdA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.57 43.0 2.98e-01 85.7% 33.9%
3ehmA03 1.20.120.840 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SusD-like, tetratrico peptide repeats domain 0.55 42.0 3.61e-01 92.1% 88.1%
5dckA00 1.10.1200.30 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Retrovirus capsid C-terminal domain 0.54 46.0 4.49e-01 100.0% 87.3%
7aj9A01 1.10.101.10 Mainly Alpha › Orthogonal Bundle › Muramoyl-pentapeptide Carboxypeptidase; domain 1 › PGBD-like superfamily/PGBD 0.51 38.0 3.76e-01 84.1% 77.6%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3739093 103.1.1.25 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › Rap1_C_Sp 0.71 60.0 5.94e-01 100.0% 91.2%
3273217 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 53.0 4.61e-01 81.0% 81.1%
3768971 192.29.1.11 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA 0.69 60.0 5.06e-01 100.0% 93.6%
4955279 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.64 48.0 3.44e-01 82.5% 96.0%
5032080 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 54.0 4.48e-01 100.0% 83.5%
3178032 101.1.17.0 alpha arrays › HTH › HTH › FF domain 0.59 49.0 4.82e-01 96.8% 98.6%
4983939 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.58 45.0 3.56e-01 87.3% 93.8%
3687571 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.58 49.0 3.82e-01 95.2% 67.9%
4669775 4095.1.1.1 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_N 0.58 44.0 3.84e-01 84.1% 90.0%
3695576 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.57 44.0 2.75e-01 87.3% 71.2%
3472174 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 44.0 2.68e-01 88.9% 11.6%
3167157 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 42.0 3.28e-01 82.5% 54.2%
4332288 4095.1.1.1 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_N 0.56 49.0 3.97e-01 92.1% 86.4%
4286470 5067.1.1.2 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF 0.55 42.0 3.06e-01 85.7% 49.8%
3537025 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 47.0 2.78e-01 100.0% 71.5%
3388696 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.55 40.0 3.65e-01 77.8% 57.6%
3213117 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.54 46.0 4.08e-01 98.4% 83.2%
3699309 109.4.1.11 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PI3Ka 0.54 37.0 2.79e-01 73.0% 54.1%
5026255 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 42.0 3.10e-01 88.9% 77.1%
3394211 109.4.1.338 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RIC1 0.53 47.0 3.21e-01 98.4% 29.3%
3516297 2484.1.1.21 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › BcrAD_BadFG 0.51 44.0 3.19e-01 100.0% 43.5%
D5 medium residues 288-398
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08706.17 best D5_N 38.1 2.60e-09 92.8% 59.9%
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2qkdA02 2.60.120.1040 Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain 0.64 43.0 3.95e-01 95.5% 53.6%
6ljaA01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.63 44.0 3.07e-01 85.6% 21.9%
3ismC01 1.25.40.240 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ku, C-terminal domain 0.63 42.0 3.72e-01 82.9% 48.7%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.61 45.0 4.40e-01 92.8% 70.2%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.60 39.0 4.16e-01 85.6% 73.7%
2mabA00 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.60 41.0 4.20e-01 99.1% 71.6%
3ztaA00 1.10.490.130 Mainly Alpha › Orthogonal Bundle › Globin-like › 0.60 44.0 4.12e-01 89.2% 61.2%
1zcdA00 1.20.1530.10 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain 0.59 46.0 3.24e-01 85.6% 71.3%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.58 39.0 4.25e-01 85.6% 82.4%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.58 42.0 4.17e-01 82.0% 70.6%
2efeA01 1.10.246.120 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.58 37.0 4.17e-01 89.2% 87.7%
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 32.0 4.10e-01 79.3% 96.7%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 34.0 4.04e-01 85.6% 87.8%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 47.0 4.69e-01 88.3% 86.3%
4in3B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 41.0 2.60e-01 73.9% 92.2%
4ehsA00 1.10.860.10 Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A 0.57 45.0 4.35e-01 83.8% 77.4%
2wfwA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.57 23.0 3.06e-01 82.0% 65.5%
1ywyA00 3.40.1170.40 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › Protein of unknown function DUF3203 0.57 27.0 3.28e-01 70.3% 67.6%
1kf6C00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.56 40.0 3.89e-01 75.7% 72.3%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.56 44.0 4.48e-01 89.2% 86.2%
5k29A00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.55 39.0 4.10e-01 84.7% 82.5%
4nqwA01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.55 31.0 3.48e-01 82.0% 71.4%
3bemB00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.55 47.0 3.89e-01 96.4% 70.3%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.54 33.0 3.74e-01 85.6% 83.5%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.54 32.0 3.74e-01 82.9% 88.7%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 39.0 4.22e-01 85.6% 89.4%
3nftA00 1.20.1710.10 Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like 0.53 45.0 3.42e-01 91.0% 92.4%
4flbA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 32.0 3.02e-01 85.6% 48.9%
2mqaA00 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.53 35.0 3.45e-01 91.0% 59.2%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.53 45.0 4.05e-01 92.8% 89.6%
2vzbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 42.0 3.68e-01 84.7% 78.4%
4uiqB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 42.0 3.80e-01 85.6% 82.4%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.53 41.0 4.16e-01 83.8% 88.6%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.52 37.0 3.61e-01 86.5% 66.7%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 39.0 3.83e-01 81.1% 73.3%
1wjzA00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.52 37.0 3.93e-01 94.6% 87.2%
4by6D02 1.25.40.800 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 37.0 3.00e-01 85.6% 36.9%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.50 34.0 3.78e-01 89.2% 89.4%
3e9lA02 1.20.80.40 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region 0.50 34.0 3.62e-01 80.2% 80.0%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3954609 101.1.2.749 alpha arrays › HTH › HTH › winged helix domain › D5_N 0.84 68.0 7.31e-01 97.3% 98.9%
3720226 3860.1.1.0 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm 0.69 43.0 3.98e-01 71.2% 51.1%
3518386 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.65 40.0 4.72e-01 75.7% 90.7%
4641055 2004.1.1.6 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran,oligo_HPY 0.64 55.0 3.71e-01 91.0% 36.2%
3238747 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.63 45.0 3.84e-01 74.8% 84.4%
3448385 192.4.1.0 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.62 35.0 3.49e-01 82.9% 52.2%
3890229 603.1.1.64 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › CUPID 0.61 38.0 4.10e-01 75.7% 72.6%
4065938 604.39.1.3 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ECF-ribofla_trS 0.61 51.0 4.41e-01 91.9% 83.4%
4203622 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.60 50.0 4.24e-01 88.3% 94.9%
3743268 3991.1.1.2 alpha bundles › Rabin8 C-terminal domain › Rabin8 C-terminal domain › Rabin8 C-terminal domain › RAB3A-like_C 0.60 43.0 3.79e-01 74.8% 61.8%
4018012 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.59 45.0 2.92e-01 79.3% 22.1%
3169326 192.15.1.77 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › OST3_OST6 0.59 42.0 3.85e-01 73.9% 69.0%
3976109 632.7.1.61 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › BREX_BrxC_helical 0.59 40.0 4.16e-01 83.8% 74.3%
3235137 5001.1.1.59 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sri 0.58 46.0 3.34e-01 85.6% 65.8%
5033537 4070.1.1.0 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like 0.58 46.0 3.83e-01 85.6% 62.5%
4138504 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.58 48.0 4.01e-01 88.3% 92.4%
4112673 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.58 47.0 4.04e-01 88.3% 94.4%
3742303 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.58 48.0 3.93e-01 88.3% 92.3%
5061943 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.57 49.0 4.72e-01 98.2% 84.0%
3595987 10.28.1.0 beta sandwiches › jelly-roll › Jelly-roll domain in Zinc finger protein ZPR1 › Jelly-roll domain in Zinc finger protein ZPR1 0.57 41.0 3.71e-01 95.5% 54.7%
3708446 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.57 34.0 3.75e-01 84.7% 75.3%
3581268 604.1.1.104 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › ANC1_spectrin 0.57 40.0 4.35e-01 84.7% 86.3%
3325892 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.56 36.0 4.12e-01 85.6% 88.7%
5042298 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.56 47.0 4.11e-01 100.0% 58.3%
3656485 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.56 48.0 3.89e-01 97.3% 47.6%
3572341 371.1.1.4 few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › PLA2G12 0.55 45.0 4.41e-01 97.3% 81.7%
3503635 605.1.1.133 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › OST3_OST6 0.55 39.0 3.87e-01 74.8% 85.0%
3618935 192.15.1.77 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › OST3_OST6 0.55 39.0 3.87e-01 73.0% 83.5%
3796707 2485.1.1.17 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › OST3_OST6 0.54 39.0 2.85e-01 73.0% 33.1%
3693747 1021.1.1.0 a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases 0.54 32.0 3.56e-01 71.2% 75.3%
3278774 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.53 33.0 3.38e-01 80.2% 62.9%
3555578 633.22.1.15 alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) › OST3_OST6 0.53 39.0 3.99e-01 77.5% 90.0%
5056219 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.53 39.0 2.77e-01 94.6% 24.9%
3386489 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.53 40.0 3.48e-01 80.2% 74.1%
3619200 192.15.1.76 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › CUPID 0.52 41.0 3.68e-01 83.8% 63.2%
3291034 3271.1.1.1 alpha arrays › CdiA C-terminal nuclease domain › CdiA C-terminal nuclease domain › CdiA C-terminal nuclease domain › Ntox28 0.51 40.0 4.29e-01 85.6% 97.9%
4841363 150.3.1.23 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL11 0.51 43.0 3.76e-01 90.1% 87.8%
2391543 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.51 41.0 3.39e-01 85.6% 76.6%
3606818 180.1.1.0 alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase 0.51 46.0 3.88e-01 100.0% 97.9%
3374084 604.1.1.61 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF6857 0.51 39.0 3.25e-01 81.1% 69.2%
3216888 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.50 39.0 3.43e-01 83.8% 68.2%
D6 medium residues 697-796
PDB