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IMGVR_UViG_3300044580_000331-3300044580-Ga0485776_0002305_12800_13090

Arc-Vir

IMGVR_UViG_3300044580_000331-3300044580-Ga0485776_0002305_12800_13090

Quality

82.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 37-96
PDB
Domain cluster: representative
CATH (59)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.77 71.0 5.72e-01 100.0% 55.0%
5svlA01 1.10.287.940 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel 0.76 68.0 6.53e-01 100.0% 88.2%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.75 64.0 6.18e-01 96.7% 82.4%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.73 55.0 4.50e-01 80.0% 45.3%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 54.0 5.31e-01 78.3% 81.2%
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.72 52.0 5.15e-01 76.7% 73.4%
4z7fB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.72 63.0 4.61e-01 100.0% 38.1%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.72 56.0 5.10e-01 96.7% 63.4%
2etnB01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.70 47.0 4.38e-01 70.0% 60.5%
2bg9C02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.70 57.0 4.17e-01 90.0% 36.9%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 54.0 5.02e-01 85.0% 68.8%
5fb0A02 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.69 47.0 3.84e-01 100.0% 38.4%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.69 58.0 4.21e-01 96.7% 33.0%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 58.0 5.50e-01 100.0% 85.1%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.69 57.0 4.83e-01 90.0% 86.5%
3rmiA00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.69 57.0 4.76e-01 98.3% 53.3%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.69 57.0 4.45e-01 96.7% 42.4%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.69 60.0 4.65e-01 100.0% 45.2%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.68 53.0 4.44e-01 83.3% 54.9%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 58.0 5.04e-01 98.3% 63.9%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.68 55.0 4.43e-01 88.3% 48.2%
2mpnA00 6.10.140.1340 Special › Helix non-globular › Helix Hairpins › 0.67 51.0 4.99e-01 85.0% 86.8%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 55.0 3.69e-01 100.0% 99.6%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.67 53.0 5.03e-01 91.7% 100.0%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.66 58.0 5.22e-01 100.0% 87.1%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 51.0 4.83e-01 85.0% 71.2%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.66 51.0 4.90e-01 85.0% 76.1%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.66 54.0 4.15e-01 90.0% 43.6%
2l35A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.65 51.0 5.05e-01 85.0% 81.0%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.65 50.0 5.42e-01 85.0% 98.0%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.65 57.0 4.94e-01 96.7% 92.2%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.64 54.0 4.61e-01 91.7% 70.5%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.64 56.0 5.20e-01 100.0% 94.9%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.64 55.0 4.17e-01 96.7% 41.3%
3fb2A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 51.0 4.28e-01 90.0% 53.3%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 46.0 4.54e-01 78.3% 75.4%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 54.0 5.08e-01 96.7% 97.3%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.62 54.0 4.61e-01 96.7% 67.0%
1n69B00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.60 45.0 4.17e-01 88.3% 62.5%
2avuB00 1.10.4000.10 Mainly Alpha › Orthogonal Bundle › Flagellar transcriptional activator fold › Flagellar transcriptional activator FlhD 0.60 50.0 4.17e-01 91.7% 57.7%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 52.0 4.34e-01 96.7% 56.2%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 48.0 4.43e-01 86.7% 67.5%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.60 50.0 4.30e-01 96.7% 72.5%
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.60 46.0 5.06e-01 100.0% 100.0%
2ekgB01 6.10.250.3270 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.60 47.0 4.91e-01 88.3% 91.1%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.59 51.0 4.94e-01 95.0% 100.0%
3uo2B02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.59 52.0 4.66e-01 100.0% 72.6%
5hxgB00 1.10.4000.10 Mainly Alpha › Orthogonal Bundle › Flagellar transcriptional activator fold › Flagellar transcriptional activator FlhD 0.59 50.0 4.94e-01 95.0% 93.8%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.58 43.0 4.14e-01 83.3% 69.9%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.58 50.0 4.37e-01 96.7% 67.0%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 49.0 4.71e-01 96.7% 94.4%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.58 54.0 4.94e-01 100.0% 96.1%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.57 50.0 4.22e-01 98.3% 59.6%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.57 47.0 3.55e-01 95.0% 41.0%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.56 46.0 4.26e-01 90.0% 72.7%
4ar9A02 1.10.390.20 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › 0.52 46.0 3.53e-01 100.0% 66.9%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.52 43.0 4.20e-01 100.0% 86.6%
3qavA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 42.0 3.31e-01 96.7% 45.0%
2dt7B01 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.51 34.0 3.51e-01 75.0% 72.9%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5058566 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.89 81.0 7.02e-01 100.0% 66.7%
3283999 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.86 79.0 6.46e-01 100.0% 57.1%
4989360 310.2.1.84 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › HAMP 0.84 75.0 5.82e-01 100.0% 49.2%
3989934 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.83 75.0 7.35e-01 100.0% 93.8%
4419635 5069.1.3.3 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Fumarate_red_D 0.83 70.0 5.63e-01 100.0% 49.1%
4931046 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.80 72.0 6.54e-01 100.0% 78.8%
3721541 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.79 68.0 5.79e-01 98.3% 63.0%
3975557 3782.1.1.0 a+b duplicates or obligate multimers › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related 0.78 70.0 6.89e-01 100.0% 100.0%
3472115 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.78 70.0 5.48e-01 100.0% 48.0%
3882597 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.76 65.0 5.80e-01 100.0% 70.0%
3219593 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.76 58.0 5.68e-01 83.3% 100.0%
3596488 3737.1.1.0 alpha duplicates or obligate multimers › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats 0.73 65.0 5.03e-01 96.7% 50.4%
4180835 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.72 62.0 5.96e-01 98.3% 82.9%
4859202 1076.1.1.2 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Aph-1 0.72 63.0 4.21e-01 98.3% 60.6%
4002580 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.71 62.0 4.54e-01 100.0% 35.9%
4562953 2004.1.1.43 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 0.71 64.0 4.09e-01 100.0% 40.4%
4554416 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.71 61.0 5.41e-01 98.3% 68.9%
3988424 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.71 61.0 5.97e-01 100.0% 96.9%
3695977 3922.1.1.133 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PRM1 0.71 55.0 4.58e-01 85.0% 79.0%
3591530 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 60.0 4.74e-01 98.3% 72.3%
3556027 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 55.0 4.85e-01 83.3% 62.4%
3855461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.70 55.0 4.85e-01 83.3% 62.4%
4588403 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.70 56.0 4.10e-01 85.0% 38.7%
4081214 605.1.1.290 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Phage_Nu1 0.70 59.0 5.69e-01 98.3% 90.0%
3902100 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.69 54.0 4.78e-01 83.3% 62.4%
320075 632.6.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Epsilon_antitox 0.69 58.0 5.03e-01 95.0% 67.4%
2799599 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.69 59.0 5.27e-01 96.7% 74.4%
4805104 601.19.1.1 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein 0.68 59.0 5.30e-01 98.3% 77.1%
3199608 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.67 55.0 4.51e-01 90.0% 49.1%
3988260 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.67 56.0 3.48e-01 90.0% 17.2%
4961508 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.67 57.0 5.35e-01 96.7% 85.3%
1790834 3086.1.1.1 alpha bundles › Diacylglycerol kinase (DAGK) › Diacylglycerol kinase (DAGK) › Diacylglycerol kinase (DAGK) › DAGK_prokar 0.66 59.0 5.29e-01 100.0% 71.4%
4109908 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.66 58.0 5.17e-01 100.0% 98.8%
5026085 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.66 54.0 4.65e-01 100.0% 73.1%
3386452 5050.1.1.21 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FTR1 0.65 54.0 4.25e-01 100.0% 69.7%
4107823 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.65 56.0 4.83e-01 100.0% 85.0%
3962893 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.65 57.0 4.88e-01 96.7% 67.4%
3258925 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.65 58.0 5.48e-01 96.7% 95.7%
3389029 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 55.0 4.47e-01 96.7% 53.0%
3194153 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.64 58.0 4.91e-01 98.3% 73.7%
3623842 601.24.1.0 alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 0.64 54.0 4.32e-01 96.7% 46.4%
3180581 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.63 52.0 4.66e-01 90.0% 67.1%
3619687 604.1.1.127 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › EMC4 0.63 51.0 4.35e-01 98.3% 55.5%
3721941 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.62 55.0 5.01e-01 100.0% 100.0%
60297 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.59 51.0 4.76e-01 96.7% 84.0%
4346887 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.59 50.0 4.66e-01 96.7% 89.3%
3971109 5086.1.1.85 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.58 53.0 4.88e-01 100.0% 97.3%
4025 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.57 50.0 4.22e-01 98.3% 59.6%
3719948 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.55 47.0 4.62e-01 96.7% 98.5%