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IMGVR_UViG_3300044580_000410-3300044580-Ga0485776_0000480_80985_81578
Arc-VirIMGVR_UViG_3300044580_000410-3300044580-Ga0485776_0000480_80985_81578
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 42-190
Domain cluster:
representative
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.77 | 47.0 | 5.19e-01 | 91.3% | 75.6% |
| 2l6xA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.71 | 49.0 | 4.19e-01 | 70.5% | 83.0% |
| 8anqA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.71 | 50.0 | 4.28e-01 | 71.8% | 89.3% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.70 | 50.0 | 5.31e-01 | 71.8% | 94.7% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 45.0 | 4.78e-01 | 91.3% | 72.4% |
| 1bbhA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.69 | 46.0 | 4.86e-01 | 90.6% | 74.8% |
| 3am6A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.68 | 43.0 | 3.72e-01 | 89.3% | 42.4% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.68 | 47.0 | 4.12e-01 | 70.5% | 64.1% |
| 3rkoG00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 35.0 | 4.28e-01 | 93.3% | 76.0% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.67 | 47.0 | 4.46e-01 | 71.8% | 86.4% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.67 | 46.0 | 4.86e-01 | 70.5% | 90.5% |
| 4oe8C00 | 1.10.8.1170 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.66 | 39.0 | 4.94e-01 | 89.3% | 100.0% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.66 | 39.0 | 4.94e-01 | 88.6% | 100.0% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 43.0 | 4.67e-01 | 96.6% | 81.7% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.64 | 45.0 | 4.28e-01 | 91.9% | 60.7% |
| 1z23A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.64 | 43.0 | 4.24e-01 | 88.6% | 62.6% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 48.0 | 4.47e-01 | 95.3% | 63.9% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 47.0 | 4.18e-01 | 77.2% | 79.6% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.63 | 45.0 | 4.12e-01 | 73.2% | 73.8% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 40.0 | 4.53e-01 | 91.3% | 86.9% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 42.0 | 4.94e-01 | 89.3% | 97.1% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.62 | 45.0 | 4.19e-01 | 91.9% | 60.3% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 46.0 | 5.04e-01 | 99.3% | 97.5% |
| 1st6A02 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.61 | 46.0 | 3.92e-01 | 77.9% | 72.9% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.61 | 41.0 | 3.98e-01 | 89.9% | 61.4% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.61 | 45.0 | 4.46e-01 | 74.5% | 91.5% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 43.0 | 3.91e-01 | 89.3% | 56.2% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.60 | 49.0 | 5.22e-01 | 88.6% | 100.0% |
| 1f1mA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.60 | 43.0 | 4.18e-01 | 73.2% | 88.3% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 43.0 | 4.21e-01 | 91.3% | 69.4% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 43.0 | 4.43e-01 | 94.0% | 78.1% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 49.0 | 4.28e-01 | 89.9% | 87.1% |
| 1dofA01 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.56 | 51.0 | 4.26e-01 | 96.6% | 90.6% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.56 | 47.0 | 4.75e-01 | 89.9% | 100.0% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 46.0 | 4.19e-01 | 89.3% | 88.6% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 41.0 | 3.85e-01 | 77.2% | 71.4% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 47.0 | 3.63e-01 | 89.3% | 68.1% |
| 2ptqA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.54 | 49.0 | 3.93e-01 | 100.0% | 51.4% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 39.0 | 4.18e-01 | 91.3% | 85.4% |
| 2pfmA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.54 | 49.0 | 4.03e-01 | 96.6% | 90.6% |
| 6wngA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.54 | 49.0 | 3.95e-01 | 96.6% | 87.5% |
| 4im0A04 | 1.20.1270.420 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 45.0 | 3.86e-01 | 91.3% | 80.3% |
| 5yixA00 | 1.10.601.10 | Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor | 0.53 | 44.0 | 3.38e-01 | 94.0% | 40.1% |
| 1c17M00 | 1.20.120.220 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A | 0.53 | 38.0 | 3.87e-01 | 73.2% | 95.1% |
| 1foeA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.52 | 45.0 | 4.05e-01 | 100.0% | 68.0% |
| 1auwA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.51 | 47.0 | 4.06e-01 | 99.3% | 82.9% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.51 | 40.0 | 3.76e-01 | 83.2% | 81.2% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 46.0 | 3.75e-01 | 97.3% | 70.8% |
| 3snhA02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.51 | 37.0 | 3.29e-01 | 75.2% | 88.4% |
| 2itbB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 45.0 | 4.14e-01 | 97.3% | 79.8% |
ECOD (63)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3562194 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.77 | 49.0 | 4.79e-01 | 89.3% | 60.1% |
| 4124285 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.75 | 47.0 | 4.76e-01 | 89.3% | 64.1% |
| 3619083 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.75 | 42.0 | 4.48e-01 | 87.2% | 62.2% |
| 3677692 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 49.0 | 5.01e-01 | 70.5% | 99.3% |
| 3798573 | 601.1.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C | 0.71 | 45.0 | 4.53e-01 | 91.3% | 61.9% |
| 3411201 | 601.1.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C | 0.70 | 48.0 | 4.53e-01 | 70.5% | 73.3% |
| 4944283 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 44.0 | 4.51e-01 | 91.3% | 68.6% |
| 3740238 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.67 | 47.0 | 4.65e-01 | 71.8% | 91.2% |
| 3306059 | 3755.4.1.46 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › NET2A | 0.66 | 47.0 | 4.07e-01 | 73.2% | 90.6% |
| 5008363 | 5069.1.1.26 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › NrfD | 0.66 | 51.0 | 4.39e-01 | 81.2% | 80.0% |
| 3459613 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 45.0 | 4.37e-01 | 70.5% | 95.8% |
| 3393914 | 5054.1.1.9 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PKD_channel | 0.64 | 47.0 | 3.71e-01 | 74.5% | 50.4% |
| 3619596 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.64 | 48.0 | 4.20e-01 | 76.5% | 81.4% |
| 3974674 | 5039.1.1.1 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 | 0.64 | 45.0 | 4.30e-01 | 91.9% | 61.7% |
| 4955364 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.64 | 46.0 | 4.05e-01 | 73.8% | 89.3% |
| 3653697 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.64 | 47.0 | 4.13e-01 | 77.2% | 74.1% |
| 4987134 | 5069.1.1.26 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › NrfD | 0.63 | 50.0 | 4.32e-01 | 82.6% | 75.6% |
| 3962352 | 192.29.1.146 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF2231 | 0.63 | 46.0 | 4.64e-01 | 91.9% | 74.5% |
| 3276733 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.62 | 43.0 | 4.37e-01 | 70.5% | 84.0% |
| 5047544 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.62 | 44.0 | 4.49e-01 | 71.8% | 93.8% |
| 5039160 | 5039.1.1.0 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like | 0.62 | 44.0 | 4.59e-01 | 91.9% | 78.6% |
| 4945112 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.62 | 46.0 | 4.52e-01 | 78.5% | 95.8% |
| 5047855 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 44.0 | 4.52e-01 | 73.8% | 93.1% |
| 3420563 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.61 | 36.0 | 3.77e-01 | 89.3% | 60.7% |
| 3703824 | 5054.1.1.9 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PKD_channel | 0.61 | 43.0 | 3.51e-01 | 71.8% | 56.7% |
| 3821611 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 43.0 | 4.06e-01 | 91.3% | 60.0% |
| 3872311 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.61 | 55.0 | 5.05e-01 | 95.3% | 77.8% |
| 3658108 | 611.7.1.15 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Rx_N | 0.61 | 39.0 | 4.02e-01 | 91.9% | 66.2% |
| 3428029 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.60 | 40.0 | 4.78e-01 | 87.2% | 100.0% |
| 3215766 | 192.29.1.24 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM237 | 0.60 | 46.0 | 4.59e-01 | 91.3% | 78.0% |
| 3478703 | 192.29.1.24 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM237 | 0.60 | 43.0 | 3.97e-01 | 74.5% | 83.6% |
| 3437020 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.60 | 44.0 | 4.42e-01 | 91.3% | 73.5% |
| 5046013 | 5039.1.1.0 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like | 0.60 | 43.0 | 4.41e-01 | 93.3% | 76.2% |
| 3978379 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.60 | 47.0 | 4.54e-01 | 82.6% | 95.3% |
| 3419627 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.60 | 43.0 | 4.31e-01 | 73.2% | 89.3% |
| 3792852 | 604.12.1.61 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Clc-like | 0.60 | 42.0 | 4.41e-01 | 93.3% | 77.9% |
| 3328924 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.59 | 45.0 | 4.23e-01 | 78.5% | 83.3% |
| 4947851 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.59 | 42.0 | 4.29e-01 | 73.8% | 99.3% |
| 3794336 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.58 | 45.0 | 4.41e-01 | 96.6% | 74.4% |
| 3590126 | 109.3.1.311 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF26635 | 0.58 | 41.0 | 3.70e-01 | 71.1% | 73.7% |
| 3822775 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.58 | 41.0 | 4.07e-01 | 73.2% | 84.3% |
| 3420180 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.57 | 34.0 | 3.45e-01 | 85.9% | 57.9% |
| 3581398 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 40.0 | 4.19e-01 | 71.1% | 97.8% |
| 3306934 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.57 | 39.0 | 4.46e-01 | 89.3% | 95.5% |
| 3466552 | 3755.4.1.17 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N | 0.57 | 40.0 | 4.08e-01 | 71.8% | 91.0% |
| 3174437 | 601.1.2.63 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HIP1R | 0.56 | 48.0 | 4.48e-01 | 91.3% | 90.3% |
| 3321831 | 192.29.1.115 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF599 | 0.56 | 49.0 | 4.28e-01 | 92.6% | 69.8% |
| 3377718 | 633.21.1.18 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom | 0.56 | 43.0 | 4.45e-01 | 96.6% | 84.1% |
| 3254868 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.55 | 38.0 | 3.06e-01 | 85.2% | 37.8% |
| 3437243 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.55 | 41.0 | 4.34e-01 | 91.3% | 87.4% |
| 3456024 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.55 | 42.0 | 4.30e-01 | 89.9% | 82.1% |
| 3650757 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.54 | 41.0 | 3.76e-01 | 86.6% | 61.6% |
| 3294544 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.53 | 49.0 | 4.24e-01 | 99.3% | 77.8% |
| 3406588 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.53 | 45.0 | 4.19e-01 | 91.3% | 75.0% |
| 4346171 | 602.1.1.3 ↗ | alpha arrays › L-aspartase middle domain-like › L-aspartase middle domain-like › L-aspartase middle domain-like › Lyase_aromatic | 0.52 | 47.0 | 3.71e-01 | 99.3% | 92.8% |
| 3997336 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 42.0 | 4.51e-01 | 96.6% | 100.0% |
| 3433667 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.52 | 39.0 | 3.98e-01 | 88.6% | 78.0% |
| 3226174 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.52 | 40.0 | 3.29e-01 | 81.2% | 84.2% |
| 3555824 | 4177.2.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › TBK1_CCD1 | 0.51 | 44.0 | 3.59e-01 | 91.3% | 77.8% |
| 3415708 | 4177.2.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › TBK1_CCD1 | 0.51 | 44.0 | 3.72e-01 | 91.9% | 75.1% |
| 4404045 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.51 | 42.0 | 3.64e-01 | 89.3% | 58.2% |
| 3426213 | 109.3.1.143 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › TMEM33_Pom33 | 0.51 | 43.0 | 3.79e-01 | 91.9% | 75.6% |
| 4322633 | 4177.2.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › IKBKB_SDD | 0.51 | 43.0 | 3.51e-01 | 91.3% | 69.5% |