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IMGVR_UViG_3300045988_178991-3300045988-Ga0495776_136811_45785_46564
Arc-VirIMGVR_UViG_3300045988_178991-3300045988-Ga0495776_136811_45785_46564
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-169
Domain cluster:
representative
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.72 | 29.0 | 3.94e-01 | 92.2% | 70.9% |
| 4hzuS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.69 | 39.0 | 3.94e-01 | 72.5% | 54.9% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.63 | 42.0 | 3.99e-01 | 95.2% | 56.1% |
| 4huqS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.63 | 38.0 | 3.88e-01 | 74.9% | 59.8% |
| 1b68A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.62 | 48.0 | 5.23e-01 | 95.8% | 100.0% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.61 | 40.0 | 4.48e-01 | 96.4% | 85.2% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 44.0 | 4.90e-01 | 93.4% | 100.0% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 35.0 | 3.66e-01 | 83.8% | 61.4% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 44.0 | 4.81e-01 | 95.8% | 97.0% |
| 3f1xA01 | 1.10.3130.10 | Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 | 0.58 | 44.0 | 4.67e-01 | 91.6% | 89.9% |
| 8b2sA01 | 1.10.530.40 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.58 | 31.0 | 3.26e-01 | 88.0% | 55.2% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.57 | 32.0 | 3.69e-01 | 89.2% | 75.2% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.57 | 36.0 | 4.31e-01 | 73.1% | 96.3% |
| 3mfnB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.56 | 40.0 | 4.53e-01 | 94.0% | 98.4% |
| 3fajA00 | 1.20.120.950 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 | 0.55 | 33.0 | 4.05e-01 | 94.6% | 96.0% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 32.0 | 3.56e-01 | 87.4% | 71.4% |
| 6nplA01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.55 | 46.0 | 3.36e-01 | 90.4% | 69.8% |
| 7ae2A01 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.54 | 41.0 | 4.45e-01 | 95.2% | 95.6% |
| 4bjmC00 | 1.20.58.1680 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 40.0 | 3.67e-01 | 98.2% | 59.5% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 34.0 | 3.79e-01 | 85.0% | 78.3% |
| 6dewA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 36.0 | 3.53e-01 | 99.4% | 61.6% |
| 4q4hA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.52 | 46.0 | 3.82e-01 | 99.4% | 98.1% |
| 3zojA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.52 | 43.0 | 3.70e-01 | 95.8% | 55.9% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 41.0 | 3.70e-01 | 83.2% | 87.4% |
| 6klvB00 | 1.20.810.10 | Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C | 0.51 | 44.0 | 3.42e-01 | 94.6% | 73.7% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 42.0 | 4.07e-01 | 86.8% | 91.0% |
| 1ezvC00 | 1.20.810.10 | Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C | 0.51 | 44.0 | 3.41e-01 | 94.6% | 71.4% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.51 | 38.0 | 4.18e-01 | 93.4% | 98.5% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.50 | 42.0 | 3.81e-01 | 89.8% | 79.3% |
| 2ks9A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 41.0 | 3.24e-01 | 90.4% | 40.2% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.50 | 42.0 | 3.06e-01 | 89.8% | 79.2% |
| 2x64A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.50 | 32.0 | 3.83e-01 | 97.0% | 95.6% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3691418 | 601.19.1.21 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › DUF7605 | 0.69 | 64.0 | 5.38e-01 | 100.0% | 98.9% |
| 4021606 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.65 | 59.0 | 3.88e-01 | 98.8% | 29.1% |
| 3721392 | 3615.1.1.28 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › DUF7605 | 0.64 | 59.0 | 5.05e-01 | 99.4% | 91.7% |
| 3547013 | 621.1.1.8 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › GVIN1 | 0.64 | 41.0 | 4.84e-01 | 78.4% | 92.2% |
| 3949737 | 5057.1.1.35 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › GtrA_DPMS_TM | 0.64 | 47.0 | 5.27e-01 | 91.6% | 97.7% |
| 3960588 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.64 | 42.0 | 4.17e-01 | 79.6% | 62.3% |
| 3958572 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.62 | 37.0 | 4.01e-01 | 76.0% | 69.3% |
| None | — | 0.61 | 36.0 | 3.06e-01 | 76.6% | 36.9% | |
| 4077080 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.60 | 55.0 | 4.74e-01 | 100.0% | 67.5% |
| 3634180 | 1075.4.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 | 0.58 | 44.0 | 3.94e-01 | 77.2% | 72.2% |
| 3994851 | 601.1.2.63 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HIP1R | 0.58 | 40.0 | 4.17e-01 | 95.2% | 77.3% |
| 3278714 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.57 | 40.0 | 3.75e-01 | 98.2% | 57.6% |
| 3592441 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 50.0 | 5.14e-01 | 98.2% | 100.0% |
| 3590438 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.56 | 39.0 | 4.39e-01 | 92.2% | 90.8% |
| 4024166 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.56 | 42.0 | 4.25e-01 | 94.0% | 77.1% |
| 3628755 | 109.4.1.1493 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Zw10_middle, ZW10_C, ZW10_C2 | 0.55 | 43.0 | 2.79e-01 | 80.8% | 21.8% |
| 3220678 | 5001.1.1.33 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srh | 0.55 | 49.0 | 3.93e-01 | 94.6% | 82.9% |
| 4390628 | 5068.1.1.1 ↗ | alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Cytochrom_B_C | 0.55 | 36.0 | 3.75e-01 | 80.8% | 68.8% |
| 3725025 | 5001.1.1.125 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF7703 | 0.55 | 42.0 | 3.58e-01 | 94.6% | 48.4% |
| 3188827 | 601.1.1.77 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF3176 | 0.55 | 48.0 | 4.81e-01 | 95.8% | 93.5% |
| 5075780 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.53 | 41.0 | 4.46e-01 | 94.0% | 98.5% |
| 3220413 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.53 | 43.0 | 4.51e-01 | 94.6% | 94.2% |
| 3497236 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 43.0 | 3.64e-01 | 98.8% | 52.3% |
| 4988860 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.52 | 43.0 | 4.24e-01 | 94.6% | 84.0% |
| 4877536 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.52 | 44.0 | 3.66e-01 | 92.2% | 99.0% |
| 5026838 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.51 | 45.0 | 4.00e-01 | 95.8% | 97.1% |
| 4949583 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.51 | 37.0 | 3.58e-01 | 95.8% | 65.3% |
| None | — | 0.51 | 47.0 | 3.63e-01 | 100.0% | 49.4% | |
| 4003290 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.51 | 41.0 | 3.66e-01 | 85.0% | 71.1% |
| 3918432 | 601.1.1.94 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PF27561 | 0.51 | 44.0 | 4.34e-01 | 95.8% | 96.1% |
| 3738621 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 42.0 | 3.78e-01 | 96.4% | 62.5% |
| 3638753 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 40.0 | 3.55e-01 | 94.0% | 57.9% |
| 3955486 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.51 | 42.0 | 3.83e-01 | 89.2% | 77.3% |
| 3934161 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 40.0 | 3.76e-01 | 93.4% | 67.8% |
| 3506288 | 4177.1.1.6 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg | 0.50 | 39.0 | 3.67e-01 | 83.2% | 87.4% |
D2
high
residues 181-244
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1pieA01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.57 | 47.0 | 3.42e-01 | 96.9% | 61.1% |
| 4fw1A02 | 2.30.30.10 | Mainly Beta › Roll › SH3 type barrels. › Integrase, C-terminal domain superfamily, retroviral | 0.52 | 35.0 | 3.82e-01 | 90.6% | 85.2% |
| 3mqgA02 | 2.20.70.110 | Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › | 0.52 | 31.0 | 3.65e-01 | 71.9% | 97.4% |
| 4qunA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.52 | 35.0 | 2.37e-01 | 71.9% | 30.0% |
| 6q3wD01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.51 | 41.0 | 3.16e-01 | 100.0% | 94.1% |
| 1uebA02 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.51 | 37.0 | 3.79e-01 | 78.1% | 92.1% |
| 4m4zA01 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.51 | 35.0 | 3.91e-01 | 87.5% | 100.0% |
| 7cfdA01 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.51 | 36.0 | 3.55e-01 | 90.6% | 68.5% |
| 3p8aA02 | 2.60.40.4320 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.50 | 35.0 | 3.22e-01 | 76.6% | 53.3% |
| 6bhdA03 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.50 | 41.0 | 4.13e-01 | 96.9% | 90.5% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3843756 | 376.1.1.20 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_UBOX | 0.56 | 39.0 | 3.45e-01 | 73.4% | 68.4% |
| 3953820 | 2003.1.3.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › DAO | 0.54 | 42.0 | 2.67e-01 | 90.6% | 54.0% |
| 3336463 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.54 | 42.0 | 3.96e-01 | 85.9% | 91.0% |
| 3902780 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.51 | 40.0 | 3.50e-01 | 100.0% | 55.2% |
| 3883159 | 4.1.1.9 ↗ | beta barrels › SH3 › SH3 › SH3 › TUDOR | 0.51 | 38.0 | 3.43e-01 | 92.2% | 57.8% |
| 1114686 | 4.1.1.8 ↗ | beta barrels › SH3 › SH3 › SH3 › IN_DBD_C | 0.51 | 35.0 | 3.73e-01 | 90.6% | 82.1% |
| 3514970 | 4.1.1.9 ↗ | beta barrels › SH3 › SH3 › SH3 › TUDOR | 0.51 | 38.0 | 3.46e-01 | 92.2% | 58.9% |