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IMGVR_UViG_3300045988_178991-3300045988-Ga0495776_136811_8695_8883

Arc-Vir

IMGVR_UViG_3300045988_178991-3300045988-Ga0495776_136811_8695_8883

Quality

77.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-50
PDB
Domain cluster: representative
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1p49A02 1.10.287.550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.90 81.0 7.67e-01 100.0% 91.5%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.89 80.0 6.68e-01 100.0% 60.5%
4fvmA06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.88 68.0 6.98e-01 98.0% 87.5%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.85 78.0 6.66e-01 100.0% 94.8%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.84 75.0 5.32e-01 100.0% 37.9%
1y6xA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.81 69.0 5.68e-01 100.0% 54.0%
2zueA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.81 69.0 5.13e-01 94.0% 45.4%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.80 71.0 5.04e-01 100.0% 41.5%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 72.0 6.23e-01 100.0% 72.0%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 70.0 4.49e-01 100.0% 30.5%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 70.0 6.06e-01 100.0% 68.8%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.79 70.0 6.21e-01 100.0% 81.7%
1yq1A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.79 66.0 5.11e-01 100.0% 42.9%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 59.0 5.53e-01 100.0% 66.1%
1jkvA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 67.0 4.52e-01 100.0% 73.1%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.78 67.0 5.21e-01 100.0% 43.9%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.77 65.0 6.14e-01 100.0% 79.0%
1z5zA02 1.20.120.850 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SWI2/SNF2 ATPases, N-terminal domain 0.76 61.0 5.35e-01 90.0% 59.2%
1chuA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.75 59.0 4.96e-01 100.0% 50.0%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.75 65.0 5.44e-01 100.0% 59.1%
1ni3A03 1.10.150.300 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain 0.75 63.0 5.12e-01 92.0% 60.4%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 64.0 6.14e-01 100.0% 100.0%
2xs1A01 1.25.40.280 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains 0.75 62.0 3.72e-01 100.0% 13.2%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 62.0 4.97e-01 100.0% 48.0%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.73 61.0 4.63e-01 100.0% 38.4%
2k9pA00 1.10.287.920 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Pheromone alpha factor receptor. 0.73 56.0 4.84e-01 86.0% 57.5%
4fppB01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.72 60.0 5.51e-01 100.0% 71.8%
3cbuA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.72 62.0 4.60e-01 100.0% 37.3%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.72 59.0 5.08e-01 92.0% 69.5%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 61.0 5.45e-01 100.0% 65.8%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.71 59.0 4.65e-01 100.0% 71.8%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.70 58.0 4.60e-01 100.0% 43.2%
5lnkA00 1.20.58.1610 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 0.70 55.0 4.39e-01 100.0% 40.9%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.69 56.0 4.01e-01 100.0% 33.0%
2i7uA00 6.10.250.1010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.69 59.0 5.54e-01 100.0% 79.0%
2btqB03 1.10.287.600 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 60.0 5.90e-01 100.0% 96.2%
1ailA00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.68 56.0 5.14e-01 96.0% 68.6%
4cb8A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.68 58.0 3.36e-01 100.0% 10.2%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.68 56.0 4.38e-01 100.0% 41.7%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.67 55.0 4.54e-01 100.0% 53.9%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 57.0 3.94e-01 100.0% 30.3%
2q1kA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.67 55.0 5.49e-01 100.0% 96.2%
3e22A03 1.10.287.600 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 56.0 5.51e-01 100.0% 94.4%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.66 53.0 4.99e-01 100.0% 75.4%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 52.0 3.85e-01 100.0% 33.3%
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.65 51.0 4.92e-01 100.0% 82.8%
7xxiA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 53.0 3.36e-01 100.0% 17.2%
1r4gA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.64 45.0 4.44e-01 98.0% 71.7%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.64 52.0 4.72e-01 100.0% 65.8%
3s6jE02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.64 54.0 4.88e-01 96.0% 98.6%
2xzmO02 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.64 51.0 4.74e-01 100.0% 74.3%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 52.0 4.25e-01 100.0% 52.8%
3ilkA02 1.10.8.590 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.63 55.0 4.95e-01 96.0% 70.6%
1e7uA05 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.55 46.0 3.15e-01 96.0% 55.0%
1w36C06 1.10.10.990 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.54 45.0 4.03e-01 94.0% 66.7%
1t07A00 1.10.3880.10 Mainly Alpha › Orthogonal Bundle › YggX-like › Fe(II) trafficking protein YggX 0.51 44.0 3.74e-01 98.0% 86.4%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3264065 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.89 71.0 5.98e-01 100.0% 53.8%
4613072 101.1.2.721 alpha arrays › HTH › HTH › winged helix domain › MarR_2, PF27113 0.89 70.0 4.77e-01 100.0% 26.1%
4219465 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.88 72.0 5.45e-01 100.0% 40.0%
3922358 3560.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med8 0.87 78.0 5.31e-01 100.0% 29.4%
3453933 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.87 71.0 5.37e-01 100.0% 40.0%
4247116 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.87 70.0 5.33e-01 100.0% 40.0%
4078998 5059.1.1.2 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res 0.86 77.0 5.97e-01 100.0% 47.6%
3297770 622.4.1.26 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA 0.86 67.0 5.63e-01 100.0% 50.6%
3973158 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.86 67.0 5.72e-01 100.0% 53.8%
3370743 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.85 66.0 5.66e-01 100.0% 53.8%
4041347 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.83 67.0 5.14e-01 100.0% 40.0%
5031388 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.83 73.0 5.59e-01 100.0% 46.5%
3976663 3812.1.1.1 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E 0.83 73.0 6.75e-01 100.0% 87.7%
4937862 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.83 73.0 5.64e-01 100.0% 65.5%
3741727 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.82 71.0 4.77e-01 100.0% 26.8%
4463756 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.82 63.0 5.72e-01 100.0% 61.4%
5002748 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.82 68.0 5.92e-01 100.0% 61.3%
3805996 192.10.1.7 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › HisKA 0.80 73.0 6.30e-01 100.0% 76.0%
4929436 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.79 71.0 6.02e-01 100.0% 75.0%
3554931 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.79 66.0 6.50e-01 94.0% 100.0%
4114191 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.79 69.0 5.45e-01 100.0% 55.2%
3874058 6158.1.1.0 alpha bundles › Nucleoporin p58/p45 helical region › Nucleoporin p58/p45 helical region › Nucleoporin p58/p45 helical region 0.79 65.0 5.39e-01 100.0% 52.2%
4981299 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.79 69.0 5.46e-01 98.0% 71.0%
5050359 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.79 65.0 5.88e-01 100.0% 67.1%
4684 192.15.1.2 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r 0.76 65.0 6.05e-01 100.0% 87.7%
3477166 5059.1.1.4 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Nuc_sug_transp 0.74 65.0 4.93e-01 100.0% 42.5%
4857875 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.73 63.0 5.37e-01 100.0% 76.2%
5048467 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.72 58.0 4.24e-01 100.0% 32.4%
3569033 3538.1.1.8 extended segments › MerF › MerF › MerF › PF28754 0.71 60.0 5.89e-01 100.0% 98.2%
3731364 3922.1.1.137 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › HisKA 0.71 59.0 5.53e-01 100.0% 98.5%
3372032 5028.1.1.0 extended segments › Sec-beta subunit › Sec-beta subunit › Sec-beta subunit 0.70 60.0 5.87e-01 100.0% 100.0%
3603032 622.1.1.0 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.70 59.0 5.07e-01 100.0% 63.5%
5048188 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.69 56.0 4.11e-01 100.0% 31.9%
3974197 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 56.0 5.01e-01 100.0% 63.7%
5050301 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.68 54.0 4.76e-01 98.0% 76.2%
4116779 603.1.1.174 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HisKA 0.67 54.0 4.91e-01 100.0% 68.0%
4029817 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.65 52.0 4.94e-01 100.0% 75.4%
4965632 192.7.1.85 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › DUF4349 0.65 52.0 4.94e-01 100.0% 76.9%
4955780 3939.1.1.387 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › DUF4349 0.65 52.0 4.93e-01 100.0% 98.5%
3776400 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.64 51.0 4.59e-01 100.0% 62.5%
3461004 616.1.1.0 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.64 54.0 4.85e-01 100.0% 76.0%
3944446 5069.1.3.1 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt 0.62 53.0 4.45e-01 98.0% 56.5%
3592085 4015.1.1.1 alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 0.60 44.0 2.86e-01 84.0% 16.2%