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IMGVR_UViG_3300046055_000003-3300046055-Ga0496807_04072_3664_4224

Arc-Vir

IMGVR_UViG_3300046055_000003-3300046055-Ga0496807_04072_3664_4224

Quality

87.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-37_102-183
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.70 28.0 3.71e-01 71.6% 65.2%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.62 43.0 4.87e-01 72.4% 94.3%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.61 42.0 3.78e-01 70.7% 82.3%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 41.0 3.84e-01 75.9% 78.5%
3ltoA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.56 42.0 4.06e-01 78.4% 97.0%
4adzA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.56 38.0 4.34e-01 94.0% 91.1%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.56 34.0 3.92e-01 81.9% 83.5%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.55 42.0 3.98e-01 79.3% 88.7%
7cj3A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 43.0 3.36e-01 85.3% 57.0%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.54 40.0 4.10e-01 76.7% 91.7%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.53 39.0 3.20e-01 76.7% 74.8%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.53 28.0 3.62e-01 84.5% 93.4%
4gc0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 40.0 3.26e-01 81.9% 80.7%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.52 37.0 3.20e-01 72.4% 65.9%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 36.0 3.48e-01 70.7% 87.7%
1f6fA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 38.0 3.29e-01 77.6% 83.6%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 38.0 3.48e-01 77.6% 94.7%
1aluA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 37.0 3.39e-01 75.9% 93.6%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3573570 604.33.1.0 alpha bundles › Spectrin repeat-like › Repulsive guidance molecule (RGM) N-terminal domain › Repulsive guidance molecule (RGM) N-terminal domain 0.66 49.0 5.38e-01 78.4% 100.0%
5036646 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.66 42.0 4.64e-01 70.7% 82.2%
3974230 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.63 43.0 4.54e-01 70.7% 95.2%
4964045 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.62 39.0 4.42e-01 70.7% 84.7%
3839085 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.61 38.0 4.10e-01 70.7% 72.0%
3916145 148.1.1.5 alpha arrays › Histone-like › Histone-related › Histone › TFIID-18kDa 0.60 43.0 3.40e-01 75.0% 92.9%
3290011 3843.1.1.4 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB 0.59 35.0 3.82e-01 89.7% 70.5%
3928811 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.54 39.0 2.88e-01 76.7% 78.2%
4237 5069.1.2.1 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Respiratory nitrate reductase 1 gamma chain › Nitrate_red_gam 0.54 39.0 3.20e-01 76.7% 70.5%
5010954 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.53 34.0 3.54e-01 93.1% 68.2%
D2 high residues 49-98
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1hr7C02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.71 48.0 3.10e-01 70.0% 45.8%
8gr7A01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.68 53.0 3.21e-01 84.0% 18.4%
1e7lA02 1.10.720.10 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.68 57.0 5.53e-01 92.0% 92.7%
7miqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.67 42.0 3.24e-01 92.0% 29.1%
3iuoA00 1.10.10.1390 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › ATP-dependent DNA helicase RecQ 0.65 38.0 2.99e-01 100.0% 24.8%
2culA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.65 55.0 3.55e-01 94.0% 91.6%
5kfnA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 53.0 3.76e-01 100.0% 54.8%
1s7zA01 1.20.120.780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DNA mimic ocr 0.62 54.0 4.35e-01 100.0% 88.1%
2jvnA00 3.90.640.80 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › 0.60 51.0 3.86e-01 98.0% 84.9%
3a04A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.60 48.0 3.19e-01 98.0% 53.8%
1ufzA01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.59 44.0 4.25e-01 82.0% 72.4%
6p10B02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.59 43.0 3.64e-01 80.0% 49.5%
4l0fA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.59 48.0 2.84e-01 100.0% 11.2%
4rw0A00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.59 49.0 3.44e-01 98.0% 89.1%
1s4kA00 1.10.3100.10 Mainly Alpha › Orthogonal Bundle › Putative cytoplasmic protein › Putative cytoplasmic protein 0.58 50.0 3.79e-01 96.0% 89.2%
2ruhA00 1.10.245.10 Mainly Alpha › Orthogonal Bundle › MDM2 › SWIB/MDM2 domain 0.58 48.0 3.61e-01 96.0% 61.1%
1m3sB00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.57 51.0 3.46e-01 100.0% 63.9%
2w45A01 1.20.120.860 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Herpesvirus alkaline exonuclease, N-terminal domain 0.57 46.0 3.72e-01 100.0% 50.0%
2py5A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.56 48.0 3.31e-01 100.0% 95.1%
1rr7A02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.56 34.0 3.47e-01 74.0% 60.4%
3dl1A01 1.10.472.150 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Glucose-regulated metallo-peptidase M90, N-terminal domain 0.56 48.0 3.94e-01 100.0% 56.6%
2p67A01 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.56 35.0 3.47e-01 70.0% 55.8%
2oblA02 1.20.1270.330 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 40.0 3.54e-01 78.0% 98.6%
3cl3A01 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.52 42.0 3.69e-01 100.0% 60.7%
2p6rA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 40.0 2.87e-01 98.0% 48.0%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4319975 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.73 49.0 3.98e-01 70.0% 41.1%
5028731 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.72 49.0 4.55e-01 72.0% 58.3%
3676214 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.71 50.0 5.08e-01 78.0% 74.0%
5043822 5060.2.1.1 alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF 0.70 48.0 3.53e-01 72.0% 77.7%
3239603 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.70 59.0 4.82e-01 100.0% 59.0%
3399447 110.1.1.0 alpha arrays › DEATH domain › DEATH domain › DEATH domain 0.69 59.0 5.25e-01 100.0% 73.3%
4213361 602.1.1.3 alpha arrays › L-aspartase middle domain-like › L-aspartase middle domain-like › L-aspartase middle domain-like › Lyase_aromatic 0.69 53.0 3.24e-01 84.0% 72.2%
3689931 130.1.1.0 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.68 55.0 5.14e-01 100.0% 72.3%
3331967 397.7.1.3 few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 › DUF842 0.68 46.0 4.62e-01 100.0% 70.0%
4133327 2005.1.1.2 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1b 0.66 57.0 3.43e-01 100.0% 21.1%
3867508 110.1.1.22 alpha arrays › DEATH domain › DEATH domain › DEATH domain › SH3BP4_C, DEATH_SH3BP4 0.65 58.0 3.78e-01 100.0% 27.9%
4679975 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.65 52.0 3.10e-01 88.0% 48.2%
5059555 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.65 56.0 3.38e-01 100.0% 45.1%
4426361 110.1.1.16 alpha arrays › DEATH domain › DEATH domain › DEATH domain › SH3BP4_C 0.65 53.0 4.09e-01 100.0% 49.2%
4510352 110.1.1.22 alpha arrays › DEATH domain › DEATH domain › DEATH domain › SH3BP4_C, DEATH_SH3BP4 0.64 53.0 4.00e-01 100.0% 45.7%
3169789 130.1.1.0 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.64 54.0 5.04e-01 96.0% 81.5%
3905883 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.64 55.0 3.81e-01 100.0% 55.0%
3327914 148.1.3.205 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_At3g28540 0.63 53.0 4.88e-01 92.0% 76.9%
4020935 149.1.1.1 alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.62 53.0 3.07e-01 100.0% 40.8%
3973959 177.1.1.0 alpha bundles › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease 0.62 53.0 3.36e-01 94.0% 97.5%
3701251 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.62 55.0 3.47e-01 100.0% 28.8%
5077374 2005.1.1.2 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1b 0.61 49.0 3.00e-01 98.0% 36.3%
4363025 2008.1.1.195 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_Eco47II 0.60 51.0 3.35e-01 100.0% 30.9%
3473395 4156.1.1.4 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C 0.60 52.0 3.87e-01 100.0% 42.2%
3911637 110.1.1.2 alpha arrays › DEATH domain › DEATH domain › DEATH domain › CARD 0.60 51.0 4.18e-01 100.0% 67.0%
3667102 148.1.3.205 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_At3g28540 0.59 49.0 4.30e-01 92.0% 64.0%
3617896 110.1.1.1 alpha arrays › DEATH domain › DEATH domain › DEATH domain › Death 0.59 49.0 4.27e-01 100.0% 63.5%
3498092 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.59 50.0 3.45e-01 100.0% 46.3%
4944614 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.58 48.0 3.00e-01 96.0% 64.8%
3518379 3502.1.1.1 alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG 0.57 42.0 4.16e-01 88.0% 72.7%
4101322 2004.1.1.60 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SKI 0.56 43.0 2.98e-01 88.0% 22.6%
3695897 109.4.1.681 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.56 44.0 2.53e-01 86.0% 16.7%
2486922 7048.1.1.1 a+b complex topology › head domain of ScoMcrA › head domain of ScoMcrA › head domain of ScoMcrA › ScoMcrA_N 0.55 43.0 4.07e-01 86.0% 72.9%
3603105 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.52 37.0 3.34e-01 78.0% 53.3%
3319315 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.51 46.0 2.85e-01 100.0% 79.6%
3863863 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.51 44.0 2.73e-01 100.0% 97.9%
4984189 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.50 44.0 3.11e-01 96.0% 59.3%