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IMGVR_UViG_3300047550_000503-3300047550-Ga0485236_0010942_2286_4808
Arc-VirIMGVR_UViG_3300047550_000503-3300047550-Ga0485236_0010942_2286_4808
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 125-231
Domain cluster:
rep: IMGVR_UViG_3300008117_001899-3300008117-Ga0114351_10172021__D134-235
D2
high
residues 732-838
Domain cluster:
representative
CATH (59)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.83 | 67.0 | 6.22e-01 | 86.0% | 91.0% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.82 | 66.0 | 6.46e-01 | 85.0% | 96.6% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.77 | 62.0 | 6.20e-01 | 85.0% | 97.2% |
| 3kkbA00 | 1.20.120.880 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain | 0.75 | 55.0 | 5.20e-01 | 86.0% | 65.1% |
| 5mlc900 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.75 | 58.0 | 5.81e-01 | 81.3% | 95.3% |
| 7metA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.75 | 59.0 | 4.20e-01 | 84.1% | 47.9% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.74 | 68.0 | 5.99e-01 | 100.0% | 76.8% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.74 | 60.0 | 5.99e-01 | 85.0% | 96.3% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.72 | 66.0 | 6.19e-01 | 100.0% | 89.1% |
| 5j1gA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 57.0 | 4.46e-01 | 85.0% | 78.9% |
| 8ipqB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.71 | 55.0 | 3.97e-01 | 81.3% | 49.7% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.71 | 56.0 | 5.71e-01 | 86.0% | 92.5% |
| 2cr7A01 | 1.20.1160.11 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix | 0.70 | 33.0 | 4.32e-01 | 77.6% | 77.8% |
| 1ya0A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.70 | 58.0 | 4.68e-01 | 90.7% | 69.4% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.69 | 51.0 | 5.05e-01 | 85.0% | 72.8% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.68 | 44.0 | 5.08e-01 | 80.4% | 93.2% |
| 4aybA07 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.68 | 53.0 | 5.07e-01 | 81.3% | 90.0% |
| 3lwjA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.67 | 61.0 | 5.00e-01 | 100.0% | 69.9% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.67 | 54.0 | 4.14e-01 | 86.0% | 87.2% |
| 5ffdA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 51.0 | 4.70e-01 | 81.3% | 92.0% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 46.0 | 5.15e-01 | 72.9% | 93.8% |
| 1yozA00 | 1.10.3200.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like | 0.66 | 50.0 | 4.97e-01 | 79.4% | 77.0% |
| 4g1tA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 43.0 | 3.35e-01 | 94.4% | 29.3% |
| 4in3B00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 60.0 | 3.74e-01 | 100.0% | 74.2% |
| 7qx4A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.66 | 58.0 | 4.57e-01 | 99.1% | 48.7% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 55.0 | 5.18e-01 | 90.7% | 87.5% |
| 5uh5D02 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.66 | 52.0 | 4.74e-01 | 83.2% | 83.3% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 52.0 | 5.29e-01 | 86.9% | 100.0% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.65 | 52.0 | 5.11e-01 | 87.9% | 91.6% |
| 3jrtA00 | 1.20.120.1060 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.65 | 51.0 | 4.40e-01 | 83.2% | 75.9% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 53.0 | 4.42e-01 | 95.3% | 51.1% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.65 | 50.0 | 5.18e-01 | 84.1% | 90.7% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 51.0 | 4.42e-01 | 86.9% | 75.1% |
| 3nxcA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 58.0 | 4.88e-01 | 100.0% | 76.8% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 50.0 | 5.03e-01 | 86.0% | 93.6% |
| 2o5iN07 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.63 | 54.0 | 5.24e-01 | 90.7% | 91.4% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 50.0 | 5.10e-01 | 86.9% | 93.4% |
| 3knwB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 57.0 | 4.79e-01 | 100.0% | 74.6% |
| 1vi0A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 54.0 | 4.94e-01 | 97.2% | 80.0% |
| 2x64A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 54.0 | 5.33e-01 | 99.1% | 92.0% |
| 4flbA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 45.0 | 4.27e-01 | 94.4% | 62.6% |
| 2cazE00 | 1.20.1440.200 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Vps28 N-terminal domain | 0.61 | 49.0 | 5.03e-01 | 88.8% | 91.1% |
| 2ycdA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 52.0 | 5.09e-01 | 96.3% | 86.3% |
| 3lsjA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 54.0 | 4.84e-01 | 100.0% | 73.9% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 50.0 | 4.42e-01 | 88.8% | 65.2% |
| 2g2dA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.60 | 47.0 | 4.16e-01 | 84.1% | 94.4% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 46.0 | 4.15e-01 | 98.1% | 57.8% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 51.0 | 4.89e-01 | 98.1% | 82.9% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 47.0 | 4.68e-01 | 97.2% | 81.8% |
| 3o60A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 52.0 | 4.45e-01 | 100.0% | 65.4% |
| 3wd6A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 51.0 | 4.94e-01 | 94.4% | 88.1% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 48.0 | 4.90e-01 | 87.9% | 100.0% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.58 | 42.0 | 3.53e-01 | 83.2% | 43.5% |
| 1urvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 43.0 | 3.85e-01 | 80.4% | 90.9% |
| 1kqfC00 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.56 | 47.0 | 3.75e-01 | 92.5% | 71.8% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.56 | 45.0 | 4.18e-01 | 87.9% | 90.4% |
| 6tejB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.54 | 45.0 | 3.39e-01 | 94.4% | 93.3% |
| 8hk0C01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 47.0 | 4.19e-01 | 99.1% | 70.0% |
| 1yhuB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 37.0 | 3.41e-01 | 78.5% | 91.7% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3739436 | 601.4.1.12 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B | 0.83 | 67.0 | 6.16e-01 | 85.0% | 70.4% |
| 3775375 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.80 | 65.0 | 5.77e-01 | 86.0% | 63.3% |
| 3178828 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.77 | 61.0 | 4.27e-01 | 83.2% | 45.5% |
| 4980095 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.77 | 58.0 | 5.87e-01 | 78.5% | 91.4% |
| 3438984 | 192.15.1.176 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Cornichon | 0.77 | 57.0 | 6.31e-01 | 96.3% | 100.0% |
| 3216661 | 109.4.1.148 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EST1_DNA_bind,EST1 | 0.76 | 66.0 | 4.16e-01 | 93.5% | 36.4% |
| 2462953 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.76 | 60.0 | 4.16e-01 | 83.2% | 44.2% |
| None | — | 0.75 | 69.0 | 4.70e-01 | 100.0% | 74.4% | |
| 4022845 | 1065.1.1.1 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain › SPX | 0.75 | 65.0 | 5.14e-01 | 95.3% | 73.2% |
| 4025271 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.75 | 58.0 | 5.98e-01 | 87.9% | 88.0% |
| 5068463 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.73 | 59.0 | 4.89e-01 | 86.0% | 91.4% |
| 3418144 | 7022.1.1.1 ↗ | alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › MBOAT | 0.73 | 66.0 | 4.47e-01 | 100.0% | 76.2% |
| 4025205 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.72 | 57.0 | 5.10e-01 | 84.1% | 87.3% |
| 3963743 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.72 | 61.0 | 6.17e-01 | 87.9% | 93.3% |
| 3794845 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.70 | 57.0 | 5.12e-01 | 86.9% | 83.4% |
| 5078867 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.70 | 55.0 | 5.91e-01 | 86.0% | 100.0% |
| 3422920 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.68 | 51.0 | 4.00e-01 | 79.4% | 60.0% |
| 5043437 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.68 | 54.0 | 5.44e-01 | 85.0% | 94.3% |
| 3244235 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.68 | 51.0 | 5.27e-01 | 88.8% | 85.0% |
| 3419853 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.68 | 57.0 | 5.15e-01 | 90.7% | 76.6% |
| 3967813 | 5086.1.1.93 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA | 0.68 | 48.0 | 4.48e-01 | 72.9% | 99.2% |
| 3635280 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 58.0 | 5.30e-01 | 90.7% | 81.5% |
| 3410818 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.67 | 49.0 | 4.64e-01 | 86.0% | 64.0% |
| 5067407 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.67 | 53.0 | 5.26e-01 | 86.0% | 80.9% |
| 4523639 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.67 | 42.0 | 3.47e-01 | 85.0% | 34.7% |
| 5083776 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.67 | 53.0 | 5.62e-01 | 85.0% | 96.8% |
| 3597604 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.66 | 57.0 | 4.60e-01 | 93.5% | 80.5% |
| 5032512 | 5086.1.1.234 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › CdvA | 0.66 | 50.0 | 4.67e-01 | 81.3% | 100.0% |
| 4947322 | 192.15.1.1 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › VPS28 | 0.65 | 52.0 | 5.13e-01 | 95.3% | 80.9% |
| 3959563 | 4958.1.1.0 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit | 0.65 | 54.0 | 4.14e-01 | 88.8% | 50.6% |
| 3880244 | 603.2.1.24 ↗ | alpha bundles › STAT-like › STAT › STAT › TBCA_PH | 0.64 | 53.0 | 4.69e-01 | 89.7% | 98.7% |
| 4528712 | 109.4.1.3083 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29810 | 0.64 | 39.0 | 2.91e-01 | 77.6% | 23.7% |
| 4975841 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.63 | 44.0 | 4.48e-01 | 71.0% | 99.0% |
| 4298800 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.63 | 54.0 | 4.09e-01 | 91.6% | 49.0% |
| 3495915 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 50.0 | 3.82e-01 | 86.9% | 41.5% |
| 4934678 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 53.0 | 4.51e-01 | 94.4% | 93.3% |
| 3484031 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 49.0 | 4.61e-01 | 86.9% | 80.0% |
| 5045646 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 48.0 | 4.40e-01 | 86.0% | 68.5% |
| 3903775 | 192.8.1.419 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › PF27603 | 0.58 | 46.0 | 4.47e-01 | 84.1% | 81.7% |
| 3699806 | 7558.1.1.0 ↗ | a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase | 0.58 | 52.0 | 3.66e-01 | 100.0% | 80.9% |
| 3913790 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 49.0 | 4.80e-01 | 92.5% | 89.6% |
| 3978419 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.56 | 51.0 | 4.73e-01 | 98.1% | 88.5% |
| 3989298 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.55 | 41.0 | 3.61e-01 | 84.1% | 52.1% |
| 4981498 | 5073.1.2.0 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain | 0.53 | 49.0 | 3.05e-01 | 99.1% | 77.1% |
| 3784284 | 601.1.1.99 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Got1 | 0.52 | 45.0 | 4.39e-01 | 95.3% | 95.7% |
| 4953762 | 5073.1.2.0 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain | 0.51 | 41.0 | 3.26e-01 | 85.0% | 72.7% |
D3
medium
residues 48-124
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4dxwB01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.67 | 47.0 | 4.19e-01 | 74.0% | 88.1% |
| 5ffdA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.64 | 44.0 | 3.64e-01 | 71.4% | 74.5% |
| 4f91B04 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.63 | 46.0 | 3.77e-01 | 77.9% | 63.4% |
| 3oo3A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.63 | 49.0 | 3.16e-01 | 85.7% | 49.6% |
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.59 | 41.0 | 3.98e-01 | 71.4% | 65.1% |
| 4z5qA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.58 | 48.0 | 3.12e-01 | 92.2% | 54.3% |
| 2xkrA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.57 | 49.0 | 3.14e-01 | 94.8% | 48.6% |
| 4iluA02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.56 | 41.0 | 3.64e-01 | 76.6% | 66.7% |
| 2p01A02 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.53 | 36.0 | 3.26e-01 | 70.1% | 85.7% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4277373 | 4994.1.1.1 ↗ | alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 | 0.73 | 48.0 | 4.47e-01 | 74.0% | 55.9% |
| 3259815 | 4156.1.1.1 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 | 0.70 | 51.0 | 4.42e-01 | 77.9% | 77.5% |
| 4646569 | 4994.1.1.1 ↗ | alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 | 0.68 | 48.0 | 4.40e-01 | 74.0% | 58.9% |
| 3677344 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.64 | 49.0 | 3.11e-01 | 81.8% | 72.6% |
| 4864573 | 11.1.1.45 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Sec63 | 0.63 | 45.0 | 3.98e-01 | 75.3% | 61.2% |
| 3904078 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.62 | 41.0 | 4.27e-01 | 77.9% | 72.6% |
| 3593709 | 4156.1.1.0 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like | 0.61 | 44.0 | 3.79e-01 | 77.9% | 69.2% |
| 5048933 | 3646.1.1.1 ↗ | alpha complex topology › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › CbiQ | 0.57 | 41.0 | 2.94e-01 | 77.9% | 40.8% |
| 3273264 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.53 | 42.0 | 3.64e-01 | 83.1% | 58.3% |
| 3261028 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.51 | 40.0 | 3.92e-01 | 85.7% | 100.0% |
| 1687881 | 2484.1.1.41 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › AnmK | 0.51 | 44.0 | 2.80e-01 | 100.0% | 68.9% |
D4
medium
residues 241-288_309-319
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ragA02 | 1.10.10.430 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Phosphatase 2C, C-terminal domain suprefamily | 0.58 | 44.0 | 4.23e-01 | 96.6% | 72.1% |
D5
medium
residues 555-729
Domain cluster:
representative