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IMGVR_UViG_3300048599_000489-3300048599-Ga0498940_0007732_1951_2718

Arc-Vir

IMGVR_UViG_3300048599_000489-3300048599-Ga0498940_0007732_1951_2718

Quality

82.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-48_62-99
PDB
Domain cluster: representative
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3pmcA00 1.10.490.70 Mainly Alpha › Orthogonal Bundle › Globin-like › Histidine kinase N-terminal domain 0.75 54.0 4.51e-01 77.2% 45.5%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.73 57.0 5.60e-01 86.1% 77.6%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.72 61.0 4.98e-01 96.2% 50.3%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.72 57.0 3.92e-01 84.8% 25.6%
1q6aA00 1.10.1240.30 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain 0.71 48.0 4.36e-01 72.2% 52.3%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.70 59.0 4.79e-01 89.9% 79.0%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.70 62.0 4.01e-01 100.0% 22.5%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.68 51.0 5.55e-01 92.4% 96.9%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.68 54.0 5.52e-01 97.5% 93.2%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 52.0 5.31e-01 98.7% 85.7%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 53.0 4.81e-01 98.7% 63.8%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.67 48.0 4.82e-01 88.6% 74.7%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 62.0 4.32e-01 100.0% 59.7%
3teqB00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 57.0 5.26e-01 94.9% 76.2%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.65 53.0 5.43e-01 93.7% 94.6%
1u00A02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 46.0 4.33e-01 73.4% 63.5%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 54.0 3.76e-01 94.9% 66.2%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.65 52.0 5.08e-01 96.2% 79.3%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.64 59.0 4.67e-01 100.0% 89.0%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.64 43.0 4.56e-01 72.2% 79.4%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 49.0 5.14e-01 93.7% 97.1%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.62 46.0 4.69e-01 89.9% 80.3%
2rgnB01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.62 53.0 4.01e-01 97.5% 83.8%
3b77B02 1.10.287.210 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 50.0 4.91e-01 91.1% 98.9%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.62 39.0 3.86e-01 81.0% 59.0%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.62 46.0 4.85e-01 98.7% 88.7%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 48.0 4.17e-01 100.0% 55.0%
4efcA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.62 48.0 4.18e-01 84.8% 59.5%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 41.0 4.45e-01 84.8% 83.1%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 47.0 4.45e-01 93.7% 70.1%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 48.0 4.86e-01 94.9% 91.0%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 49.0 4.82e-01 96.2% 88.0%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.58 45.0 4.59e-01 98.7% 89.3%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 39.0 3.96e-01 83.5% 72.7%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.57 45.0 4.30e-01 94.9% 74.7%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.57 50.0 4.52e-01 100.0% 87.3%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.56 50.0 4.07e-01 100.0% 84.2%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.56 37.0 3.65e-01 86.1% 62.1%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.55 48.0 4.64e-01 97.5% 93.3%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.54 45.0 4.44e-01 94.9% 86.6%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.53 46.0 4.27e-01 97.5% 76.8%
1jalA03 1.10.150.300 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain 0.53 44.0 4.39e-01 92.4% 100.0%
3keyA01 1.10.10.1080 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain 0.50 40.0 3.86e-01 88.6% 77.0%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5030164 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.74 54.0 5.69e-01 88.6% 87.1%
3386352 4207.1.1.104 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Bac_export_2 0.73 58.0 5.16e-01 84.8% 63.6%
4964984 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.72 56.0 5.24e-01 86.1% 78.0%
4029754 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 60.0 5.85e-01 97.5% 91.8%
5017847 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.68 53.0 4.94e-01 89.9% 68.0%
4964387 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.67 55.0 5.14e-01 92.4% 78.0%
3483982 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 48.0 4.87e-01 98.7% 76.2%
3973899 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.65 54.0 4.41e-01 100.0% 49.0%
3996264 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.65 55.0 4.27e-01 92.4% 100.0%
4174593 3922.1.1.248 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF25876 0.65 50.0 5.14e-01 98.7% 85.3%
5064123 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.65 48.0 4.38e-01 78.5% 60.0%
3981585 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.65 49.0 5.01e-01 97.5% 84.0%
3658521 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.64 42.0 3.92e-01 78.5% 53.0%
3813902 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.63 46.0 4.44e-01 82.3% 66.7%
4936552 601.30.1.1 alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.60 51.0 4.23e-01 98.7% 53.3%
5083949 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.59 52.0 4.38e-01 97.5% 92.3%
4642325 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.58 51.0 4.36e-01 98.7% 93.1%
3386973 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.58 52.0 4.98e-01 98.7% 86.7%
3596737 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.57 50.0 4.27e-01 98.7% 70.0%
3947741 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.56 46.0 4.09e-01 98.7% 60.8%
3805996 192.10.1.7 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › HisKA 0.56 45.0 4.64e-01 100.0% 94.7%
4116779 603.1.1.174 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HisKA 0.56 45.0 4.64e-01 100.0% 94.7%
4463756 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.56 43.0 4.57e-01 98.7% 95.7%
3610428 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.56 44.0 4.44e-01 89.9% 85.0%
3971026 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.56 48.0 4.19e-01 98.7% 70.4%
3355429 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.54 41.0 4.48e-01 93.7% 100.0%
4935068 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.54 43.0 4.44e-01 92.4% 93.3%
3297770 622.4.1.26 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA 0.54 45.0 4.47e-01 100.0% 89.4%
4016635 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.53 45.0 4.18e-01 94.9% 80.0%
4362754 5086.1.1.86 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG 0.52 43.0 3.85e-01 94.9% 93.3%
3965830 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.52 45.0 4.17e-01 100.0% 76.0%
D2 medium residues 103-189
PDB
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5jazA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.76 45.0 4.48e-01 98.9% 57.1%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.73 43.0 4.32e-01 95.4% 58.0%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.73 63.0 5.48e-01 95.4% 76.1%
4xcgA02 3.30.260.10 Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain 0.73 61.0 5.54e-01 89.7% 99.1%
5oklA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.70 51.0 4.87e-01 75.9% 95.0%
3gziA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.68 47.0 3.61e-01 72.4% 63.5%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.65 44.0 4.80e-01 100.0% 82.4%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 39.0 4.00e-01 98.9% 61.2%
1kxpD02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.64 45.0 4.50e-01 72.4% 75.0%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.64 35.0 4.01e-01 95.4% 71.2%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.63 41.0 4.29e-01 100.0% 70.7%
3craA02 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.63 37.0 3.21e-01 92.0% 39.1%
6lumD01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.61 37.0 3.24e-01 89.7% 41.6%
1zp2A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.61 49.0 4.55e-01 87.4% 69.6%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 42.0 3.57e-01 90.8% 46.3%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 42.0 4.39e-01 90.8% 77.8%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.60 42.0 4.22e-01 100.0% 72.4%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.59 40.0 3.99e-01 71.3% 71.3%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.59 51.0 4.20e-01 94.3% 90.2%
1xmcB03 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.58 49.0 3.95e-01 94.3% 90.4%
3h4cA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.58 43.0 4.25e-01 87.4% 72.9%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 40.0 3.88e-01 72.4% 88.8%
4ag6A02 1.10.8.730 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.58 46.0 4.30e-01 87.4% 94.5%
3nufB00 1.10.1790.10 Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › PRD domain 0.56 41.0 3.89e-01 79.3% 67.9%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 44.0 3.63e-01 82.8% 65.6%
4hl4A01 1.10.8.1310 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.56 40.0 3.35e-01 73.6% 50.0%
4z7xB00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.56 46.0 3.53e-01 92.0% 62.0%
8b70A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.55 49.0 3.17e-01 100.0% 54.3%
1eq1A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.55 46.0 3.90e-01 100.0% 77.7%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.55 43.0 4.34e-01 82.8% 87.2%
7ml0M01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.55 39.0 4.04e-01 75.9% 82.9%
2bvlA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 42.0 4.25e-01 83.9% 100.0%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.54 40.0 3.96e-01 96.6% 71.6%
6jlzA01 1.20.120.1070 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain 0.54 37.0 3.52e-01 71.3% 65.7%
2pkeA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.54 41.0 4.32e-01 85.1% 100.0%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 44.0 3.60e-01 87.4% 83.6%
5fglA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 39.0 3.10e-01 79.3% 63.0%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 43.0 3.48e-01 88.5% 75.4%
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.53 40.0 4.05e-01 94.3% 79.3%
2ip6A00 1.20.1440.140 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.53 40.0 4.09e-01 85.1% 92.0%
4x28C03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 39.0 3.35e-01 100.0% 48.3%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.52 43.0 3.67e-01 89.7% 72.3%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 47.0 3.98e-01 100.0% 86.0%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.52 42.0 3.51e-01 88.5% 75.5%
1gq2A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 42.0 2.99e-01 93.1% 65.0%
1e6bA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 38.0 3.53e-01 78.2% 97.3%
4akgA06 1.10.8.710 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Dynein motor, AAA1 domain, small subdomain 0.51 40.0 3.86e-01 89.7% 78.5%
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.51 35.0 3.22e-01 85.1% 54.5%
2pybA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 41.0 3.47e-01 87.4% 87.4%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.51 41.0 4.00e-01 90.8% 78.7%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 40.0 3.37e-01 85.1% 88.6%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.51 46.0 4.22e-01 96.6% 95.4%
1owlA02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 43.0 3.88e-01 94.3% 99.2%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.50 45.0 3.88e-01 97.7% 100.0%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3579624 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.77 55.0 5.78e-01 85.1% 82.5%
3910521 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.75 42.0 3.93e-01 90.8% 46.7%
4585879 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.71 56.0 4.69e-01 85.1% 86.0%
5065759 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.70 41.0 3.58e-01 90.8% 40.0%
5056620 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.70 47.0 3.44e-01 70.1% 25.8%
3743178 592.1.1.0 alpha arrays › PWI domain-like › PWI domain › PWI domain 0.69 56.0 4.88e-01 89.7% 60.0%
5052820 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.67 50.0 3.83e-01 100.0% 35.8%
3180704 592.6.1.1 alpha arrays › PWI domain-like › Pre-mRNA-splicing helicase BRR2 plug domain › Pre-mRNA-splicing helicase BRR2 plug domain › BRR2_plug 0.67 49.0 4.52e-01 79.3% 69.6%
3742721 592.6.1.1 alpha arrays › PWI domain-like › Pre-mRNA-splicing helicase BRR2 plug domain › Pre-mRNA-splicing helicase BRR2 plug domain › BRR2_plug 0.66 49.0 4.70e-01 79.3% 80.0%
4946202 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.66 49.0 5.13e-01 80.5% 93.8%
3942099 605.1.1.209 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › AI-2E_transport 0.65 56.0 5.46e-01 100.0% 98.0%
3815745 592.6.1.1 alpha arrays › PWI domain-like › Pre-mRNA-splicing helicase BRR2 plug domain › Pre-mRNA-splicing helicase BRR2 plug domain › BRR2_plug 0.65 49.0 5.11e-01 81.6% 98.8%
4027475 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.65 52.0 5.29e-01 88.5% 97.6%
3396895 3788.1.1.0 alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) 0.64 35.0 3.84e-01 98.9% 65.7%
4457750 3567.1.1.112 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › AI-2E_transport 0.63 51.0 4.83e-01 92.0% 84.5%
4335728 192.7.1.3 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N 0.63 44.0 4.16e-01 72.4% 80.0%
4971133 604.39.1.5 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ECF_trnsprt 0.63 53.0 4.41e-01 94.3% 91.3%
5026679 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.63 55.0 3.94e-01 96.6% 63.6%
4016803 102.1.2.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase 0.63 50.0 4.96e-01 86.2% 100.0%
3333780 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.62 49.0 4.24e-01 87.4% 67.1%
5044962 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.62 43.0 4.21e-01 93.1% 66.3%
3278427 608.1.1.0 alpha arrays › AhpD-like › AhpD-like › AhpD-like 0.62 51.0 4.01e-01 90.8% 52.4%
3786647 592.6.1.1 alpha arrays › PWI domain-like › Pre-mRNA-splicing helicase BRR2 plug domain › Pre-mRNA-splicing helicase BRR2 plug domain › BRR2_plug 0.61 48.0 5.03e-01 85.1% 96.2%
5031466 186.1.1.0 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N 0.61 39.0 3.57e-01 92.0% 48.7%
3511230 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.60 37.0 3.65e-01 93.1% 56.8%
3913655 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.59 49.0 5.05e-01 92.0% 98.8%
3969540 7014.1.1.0 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain 0.59 50.0 4.38e-01 93.1% 86.2%
3476494 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.59 41.0 3.52e-01 72.4% 60.0%
3329547 604.6.1.22 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 0.58 40.0 3.74e-01 100.0% 57.3%
3880013 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.57 45.0 4.53e-01 87.4% 83.3%
3714315 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 39.0 3.73e-01 71.3% 82.9%
3788414 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.57 43.0 4.25e-01 92.0% 74.4%
4436370 5073.1.2.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.57 41.0 2.97e-01 75.9% 33.2%
3925709 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.57 44.0 3.83e-01 85.1% 78.6%
3503307 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.56 43.0 3.65e-01 85.1% 83.1%
5035606 192.29.1.304 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Exosortase_EpsH 0.56 38.0 3.20e-01 100.0% 38.7%
3925710 148.1.3.10 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_6 0.55 43.0 4.09e-01 86.2% 81.9%
3582609 101.1.10.7 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.55 44.0 3.99e-01 90.8% 63.3%
3588616 633.2.1.0 alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein 0.55 42.0 4.00e-01 82.8% 91.4%
3947473 235.1.1.9 a+b complex topology › Lysozyme-like › Lysozyme-like › Lysozyme-like › SLT 0.54 49.0 4.10e-01 100.0% 90.0%
3435434 632.1.1.13 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N 0.52 43.0 4.08e-01 94.3% 74.3%
4013606 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.51 37.0 4.01e-01 74.7% 97.1%
3580700 148.1.3.10 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_6 0.51 40.0 3.83e-01 89.7% 80.0%
D3 medium residues 190-255
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7clyA01 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.61 52.0 3.87e-01 97.0% 98.9%
3ttgA00 3.30.1360.120 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Probable tRNA modification gtpase trme; domain 1 0.60 51.0 3.31e-01 98.5% 43.9%
2ls6A00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.59 49.0 3.82e-01 98.5% 84.1%
4kh9A03 2.60.120.1370 Mainly Beta › Sandwich › Jelly Rolls › 0.57 47.0 4.05e-01 95.5% 83.2%
3itqA01 2.60.120.620 Mainly Beta › Sandwich › Jelly Rolls › q2cbj1_9rhob like domain 0.57 47.0 3.50e-01 95.5% 38.9%
2uy6C01 2.60.40.1090 Mainly Beta › Sandwich › Immunoglobulin-like › Fimbrial-type adhesion domain 0.56 45.0 3.63e-01 92.4% 71.1%
4txwA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.56 45.0 3.54e-01 93.9% 69.8%
8ehtB01 2.60.40.1090 Mainly Beta › Sandwich › Immunoglobulin-like › Fimbrial-type adhesion domain 0.56 45.0 3.57e-01 92.4% 72.1%
1n12A00 2.60.40.1090 Mainly Beta › Sandwich › Immunoglobulin-like › Fimbrial-type adhesion domain 0.56 44.0 3.64e-01 92.4% 71.7%
5y4mA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.55 45.0 3.55e-01 93.9% 58.0%
1f60A03 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.55 45.0 3.90e-01 93.9% 96.3%
4a8xA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.54 47.0 4.31e-01 100.0% 96.6%
2fp4B02 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.54 45.0 4.13e-01 98.5% 80.2%
5ikuA01 2.60.120.380 Mainly Beta › Sandwich › Jelly Rolls › 0.53 41.0 3.68e-01 89.4% 70.2%
1qhdA01 2.60.120.170 Mainly Beta › Sandwich › Jelly Rolls › 0.52 41.0 3.19e-01 92.4% 65.3%
2zotC00 2.60.40.4060 Mainly Beta › Sandwich › Immunoglobulin-like › Reeler domain 0.52 42.0 3.49e-01 98.5% 57.9%
1tedA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.52 35.0 2.79e-01 71.2% 47.0%
3at0A02 2.60.40.1290 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 40.0 3.11e-01 89.4% 85.7%
1pwaA00 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.51 42.0 3.59e-01 100.0% 98.4%
1yq5A00 2.60.120.670 Mainly Beta › Sandwich › Jelly Rolls › Minor capsid protein. 0.51 40.0 3.33e-01 97.0% 96.5%
2hw2A00 3.20.170.40 Alpha Beta › Alpha-Beta Barrel › ADP-ribosylation fold › Rifampin ADP-ribosyltransferase domain 0.50 38.0 3.18e-01 87.9% 90.6%
3on7B00 2.60.120.330 Mainly Beta › Sandwich › Jelly Rolls › B-lactam Antibiotic, Isopenicillin N Synthase; Chain 0.50 40.0 2.79e-01 95.5% 28.1%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3230490 10.4.1.19 beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › Glycoprotein 0.64 52.0 4.74e-01 92.4% 78.9%
3232071 10.4.1.19 beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › Glycoprotein 0.62 51.0 4.59e-01 93.9% 83.2%
3256391 10.12.1.53 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › 2OG-FeII_Oxy_3 0.59 49.0 3.56e-01 95.5% 36.0%
3415183 10.12.1.0 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.59 48.0 3.53e-01 93.9% 32.8%
3957269 10.32.1.270 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Mycobact_memb 0.59 48.0 4.44e-01 92.4% 79.3%
3981386 11.1.5.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.59 50.0 3.69e-01 100.0% 60.0%
1072214 10.36.1.1 beta sandwiches › jelly-roll › hypothetical protein lpg0956 N-terminal domain › hypothetical protein lpg0956 N-terminal domain › DUF4785_1st 0.58 48.0 3.76e-01 93.9% 62.0%
3212952 10.4.1.19 beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › Glycoprotein 0.58 46.0 4.27e-01 92.4% 83.3%
3401675 10.12.1.53 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › 2OG-FeII_Oxy_3 0.58 47.0 3.33e-01 95.5% 31.2%
1827785 10.12.1.53 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › 2OG-FeII_Oxy_3 0.58 48.0 3.51e-01 95.5% 37.3%
3216777 10.4.1.19 beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › Glycoprotein 0.57 47.0 4.28e-01 97.0% 82.1%
4608515 10.32.1.0 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.57 49.0 3.89e-01 100.0% 82.1%
3583460 10.12.1.53 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › 2OG-FeII_Oxy_3 0.57 48.0 3.78e-01 100.0% 58.7%
3223222 10.12.1.53 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › 2OG-FeII_Oxy_3 0.56 46.0 3.28e-01 95.5% 31.3%
5039581 10.1.2.0 beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.56 48.0 4.10e-01 100.0% 85.0%
3947769 10.32.1.10 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › BcsB 0.56 46.0 3.71e-01 95.5% 71.4%
3186921 10.12.1.17 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › 2OG-FeII_Oxy,DIOX_N 0.56 45.0 2.87e-01 93.9% 30.6%
4029599 10.12.1.53 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › 2OG-FeII_Oxy_3 0.56 45.0 2.97e-01 93.9% 36.3%
1688826 10.12.1.53 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › 2OG-FeII_Oxy_3 0.55 44.0 3.34e-01 93.9% 41.4%
3222026 10.4.1.9 beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › CUB_2 0.54 44.0 3.81e-01 97.0% 88.7%
1002429 10.3.1.4 beta sandwiches › jelly-roll › TNF-like › TNF-like › PRD1_P5_C 0.54 43.0 3.53e-01 97.0% 68.8%
4365778 304.48.1.17 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.53 43.0 2.92e-01 93.9% 27.9%
3680878 304.48.1.17 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.53 43.0 2.84e-01 93.9% 24.4%
3663219 4968.1.1.1 a+b complex topology › insertion domain in bacteriophage phi29 DNA polymerase › insertion domain in bacteriophage phi29 DNA polymerase › insertion domain in bacteriophage phi29 DNA polymerase › DNA_pol_B_2 0.53 42.0 3.75e-01 93.9% 74.3%