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IMGVR_UViG_3300048599_000489-3300048599-Ga0498940_0007732_1_1737

Arc-Vir

IMGVR_UViG_3300048599_000489-3300048599-Ga0498940_0007732_1_1737

Quality

64.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 125-185
PDB
CATH (77)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kafA00 3.90.1150.20 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription regulator MotA, C-terminal domain 0.74 61.0 5.12e-01 93.4% 56.5%
2iboA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 56.0 5.00e-01 86.9% 79.8%
2i8eA01 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 56.0 5.25e-01 86.9% 93.2%
2nqwA00 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.70 48.0 4.31e-01 72.1% 98.9%
4makB00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 55.0 5.21e-01 88.5% 100.0%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 54.0 4.61e-01 86.9% 70.9%
1hi9A02 3.30.1360.130 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Dipeptide transport protein 0.69 57.0 5.32e-01 91.8% 86.8%
7npaA02 3.30.70.3340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 59.0 5.34e-01 98.4% 88.2%
1flmA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.69 49.0 3.98e-01 77.0% 68.9%
1yqhA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 54.0 4.54e-01 86.9% 69.2%
1yj7B01 3.30.70.1530 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hypothetical protein rpa1041 0.68 54.0 5.16e-01 86.9% 85.9%
3ui3A02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 55.0 4.74e-01 90.2% 78.6%
3p1tA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.68 56.0 4.51e-01 93.4% 53.3%
2mkyA00 3.30.70.1530 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hypothetical protein rpa1041 0.67 51.0 5.20e-01 83.6% 100.0%
1earA02 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.67 53.0 5.16e-01 88.5% 78.3%
3jcmH04 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.67 52.0 4.86e-01 86.9% 88.3%
5t8uB01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.66 57.0 3.83e-01 100.0% 69.0%
2arzA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.66 46.0 3.52e-01 73.8% 63.3%
1zvpD00 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.66 54.0 4.33e-01 95.1% 89.3%
1zpwX00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 52.0 4.75e-01 86.9% 75.6%
1s7hA02 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 52.0 4.83e-01 91.8% 87.8%
3n89A02 3.30.310.210 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › 0.66 51.0 4.08e-01 90.2% 51.8%
4qmfD02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.66 51.0 4.48e-01 85.2% 78.3%
1gmuA01 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.65 51.0 4.97e-01 86.9% 79.1%
1s5jA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.65 51.0 3.86e-01 88.5% 72.6%
4mo0A00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.65 55.0 5.11e-01 100.0% 93.7%
4mz0B05 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.64 51.0 5.03e-01 90.2% 88.1%
7uvpA02 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.64 49.0 4.76e-01 86.9% 97.1%
4e9jA02 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.64 49.0 4.74e-01 85.2% 97.1%
3if4A01 2.20.20.40 Mainly Beta › Single Sheet › Anthopleurin-A › Integron cassette protein 0.64 43.0 4.73e-01 70.5% 88.0%
1l0wA03 3.30.1360.30 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › GAD-like domain 0.64 52.0 4.18e-01 96.7% 85.5%
3ezjA03 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.63 48.0 5.05e-01 85.2% 100.0%
3ossD00 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.62 50.0 3.81e-01 91.8% 73.9%
4wbtA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.62 51.0 3.95e-01 93.4% 48.6%
1fc4A02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.62 51.0 4.04e-01 95.1% 58.1%
3dpuB03 3.30.310.200 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › 0.62 47.0 4.02e-01 86.9% 87.0%
3dgpB00 3.30.70.1220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TFB5-like 0.61 46.0 4.63e-01 85.2% 85.7%
4gvbB00 3.30.70.440 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Killer toxin KP6 alpha-subunit 0.60 46.0 4.42e-01 86.9% 89.2%
3fgvA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 47.0 4.16e-01 88.5% 88.2%
2kkhA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 46.0 4.43e-01 90.2% 94.7%
2e9hA01 3.30.30.170 Alpha Beta › 2-Layer Sandwich › Defensin A-like › 0.59 46.0 3.92e-01 91.8% 64.6%
4fx5A03 1.20.120.1690 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.59 47.0 4.14e-01 93.4% 75.0%
2iewB00 3.30.470.160 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Inositol polyphosphate kinase 0.59 48.0 3.32e-01 100.0% 42.6%
3rq1D01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 46.0 3.55e-01 93.4% 35.9%
4hqeA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 41.0 3.54e-01 77.0% 60.0%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.58 48.0 4.32e-01 100.0% 91.5%
7k98E03 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.58 41.0 4.00e-01 77.0% 91.2%
3pcoB04 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.58 42.0 4.03e-01 82.0% 89.3%
2zc0A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.57 46.0 3.27e-01 96.7% 90.7%
1fxrA00 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 44.0 4.44e-01 90.2% 93.8%
6swc801 3.30.30.170 Alpha Beta › 2-Layer Sandwich › Defensin A-like › 0.57 45.0 3.81e-01 95.1% 70.7%
2rilA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 42.0 3.75e-01 86.9% 86.3%
1h3dA03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 40.0 4.01e-01 85.2% 83.6%
5trdA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 41.0 3.75e-01 83.6% 75.0%
4hw0C00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 41.0 3.65e-01 83.6% 66.7%
3rayA00 2.170.270.10 Mainly Beta › Beta Complex › Beta-clip-like › SET domain 0.54 40.0 3.02e-01 78.7% 77.4%
3l09A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 38.0 3.55e-01 77.0% 78.6%
4k22B01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 43.0 2.93e-01 90.2% 75.1%
2cxiA03 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.54 39.0 3.82e-01 82.0% 91.4%
3a2vD02 3.30.1020.10 Alpha Beta › 2-Layer Sandwich › Antioxidant, Horf6; Chain A, domain 2 › Antioxidant, Horf6; Chain A, domain2 0.54 36.0 3.17e-01 70.5% 53.7%
3axsA02 3.30.56.70 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain 0.53 41.0 4.04e-01 85.2% 87.7%
2a5yC03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 44.0 3.74e-01 98.4% 66.7%
1p4xA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.28e-01 83.6% 54.5%
3df8A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.36e-01 83.6% 60.6%
3jsyA02 3.90.105.20 Alpha Beta › Alpha-Beta Complex › Molybdopterin biosynthesis moea protein, domain 2 › Ribosomal protein L10, N-terminal fragment, domain II 0.53 40.0 3.77e-01 88.5% 80.0%
7zxkB02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 43.0 3.87e-01 96.7% 94.6%
1zarA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 39.0 3.60e-01 88.5% 73.0%
2pg4A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 40.0 3.64e-01 90.2% 78.0%
2d1hB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 37.0 3.25e-01 78.7% 59.2%
5optn00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 39.0 3.52e-01 88.5% 77.4%
5xyiK00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 39.0 3.58e-01 88.5% 73.3%
3m8eA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 40.0 3.48e-01 90.2% 72.3%
3jamK00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 39.0 3.51e-01 90.2% 70.8%
5e1wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 42.0 3.20e-01 100.0% 66.7%
4cs4A01 1.10.287.540 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.50 32.0 3.50e-01 85.2% 78.4%
4b8xA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 42.0 3.31e-01 98.4% 70.0%
3btxA00 2.60.120.590 Mainly Beta › Sandwich › Jelly Rolls › Alpha-ketoglutarate-dependent dioxygenase AlkB-like 0.50 37.0 2.57e-01 78.7% 92.2%
ECOD (84)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5059723 306.3.1.0 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.83 75.0 7.39e-01 100.0% 95.4%
4966680 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.79 72.0 7.05e-01 100.0% 93.8%
3533206 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.78 68.0 6.66e-01 96.7% 93.8%
3998582 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.78 69.0 6.61e-01 100.0% 92.9%
3470093 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.77 67.0 6.57e-01 96.7% 95.4%
4526098 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.77 68.0 6.23e-01 100.0% 81.2%
3259873 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.76 68.0 6.34e-01 100.0% 98.7%
3305375 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.74 67.0 6.39e-01 100.0% 95.7%
4990288 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.73 62.0 6.11e-01 93.4% 100.0%
4028694 306.3.1.0 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.73 61.0 6.08e-01 96.7% 95.4%
4968901 304.22.1.0 a+b two layers › Alpha-beta plaits › Urease metallochaperone UreE, C-terminal domain › Urease metallochaperone UreE, C-terminal domain 0.72 56.0 5.55e-01 86.9% 89.2%
4977215 304.117.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC 0.72 54.0 5.48e-01 83.6% 90.0%
5070107 304.56.1.0 a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like 0.71 56.0 5.37e-01 86.9% 92.9%
5081376 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.71 62.0 5.97e-01 100.0% 95.7%
5010613 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.70 61.0 6.00e-01 100.0% 95.4%
3276741 7509.1.1.0 a/b three-layered sandwiches › NIF3 (NGG1p interacting factor 3)-like › NIF3 (NGG1p interacting factor 3)-like › NIF3 (NGG1p interacting factor 3)-like 0.70 56.0 5.29e-01 90.2% 81.3%
3412173 306.5.1.0 a+b two layers › Glucose permease domain IIB-like › GTP cyclohydrolase I feedback regulatory protein, GFRP › GTP cyclohydrolase I feedback regulatory protein, GFRP 0.70 60.0 5.37e-01 100.0% 74.4%
3920472 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.69 53.0 5.33e-01 83.6% 91.7%
10517 7535.1.1.1 a/b three-layered sandwiches › Dipeptide transport protein › Dipeptide transport protein › Dipeptide transport protein › Peptidase_M55 0.69 57.0 3.71e-01 91.8% 53.6%
4227966 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.69 57.0 5.60e-01 93.4% 90.8%
3698932 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.69 53.0 5.11e-01 85.2% 98.6%
5080633 304.56.1.0 a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like 0.69 53.0 5.27e-01 86.9% 98.5%
1877679 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.69 54.0 4.61e-01 86.9% 68.0%
4467547 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.68 57.0 5.59e-01 95.1% 92.3%
3596989 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.68 53.0 4.88e-01 86.9% 86.3%
3718076 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.67 53.0 4.88e-01 91.8% 78.8%
4962807 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.66 54.0 5.31e-01 91.8% 96.9%
4025128 304.7.1.24 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › PF30120 0.66 52.0 4.85e-01 88.5% 88.7%
5050437 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.66 51.0 5.03e-01 86.9% 92.3%
4671846 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.66 54.0 5.24e-01 93.4% 98.6%
4029258 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.66 50.0 4.85e-01 85.2% 97.1%
3839289 304.54.1.0 a+b two layers › Alpha-beta plaits › CcmK-like › CcmK-like 0.66 55.0 5.14e-01 100.0% 87.5%
5057812 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.65 50.0 4.69e-01 83.6% 80.0%
4586587 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.65 49.0 4.98e-01 83.6% 86.7%
4563340 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.65 53.0 5.16e-01 93.4% 88.6%
5060568 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.64 49.0 4.98e-01 86.9% 95.0%
4325343 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.64 52.0 4.79e-01 95.1% 69.4%
5025092 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.64 52.0 4.96e-01 95.1% 82.7%
3706688 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.64 49.0 4.84e-01 85.2% 96.9%
3911302 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.64 49.0 4.83e-01 83.6% 100.0%
3967597 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.64 48.0 4.37e-01 83.6% 78.8%
4975038 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.63 49.0 4.85e-01 86.9% 92.3%
5027762 304.163.1.0 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.63 48.0 4.81e-01 86.9% 90.8%
3622943 101.1.2.28 alpha arrays › HTH › HTH › winged helix domain › eIF-5_eIF-2B 0.63 51.0 4.85e-01 93.4% 92.0%
3838053 304.14.1.0 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) 0.63 49.0 4.82e-01 86.9% 92.3%
1833454 3096.1.1.1 mixed a+b and a/b › Integron Cassette Protein Hfx_Cass5 › Integron Cassette Protein Hfx_Cass5 › Integron Cassette Protein Hfx_Cass5 › Hfx_Cass5 0.63 43.0 3.62e-01 70.5% 44.0%
4011415 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.62 48.0 4.46e-01 90.2% 81.2%
3511028 101.1.2.677 alpha arrays › HTH › HTH › winged helix domain › Sha_B_N 0.62 48.0 4.88e-01 93.4% 88.3%
4467662 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.62 49.0 4.77e-01 91.8% 91.4%
5028972 70.3.1.1 beta barrels › beta-clip › SET domain-like › SET domain-like › SET 0.62 42.0 3.30e-01 70.5% 36.0%
4061807 3016.1.1.10 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › GDC-P 0.61 48.0 4.77e-01 90.2% 93.8%
3174527 101.1.2.281 alpha arrays › HTH › HTH › winged helix domain › Tfb2 0.61 51.0 4.29e-01 100.0% 63.5%
4174817 327.16.1.17 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system › PF27474 0.61 43.0 4.57e-01 77.0% 95.9%
3183588 12.1.1.116 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Tfb2 0.61 51.0 4.49e-01 100.0% 72.0%
3400673 165.1.1.4 alpha duplicates or obligate multimers › Dimerisation interlock › SinR repressor dimerisation domain-like › SinR repressor dimerisation domain-like › Tfb2 0.61 51.0 4.45e-01 100.0% 72.0%
4995545 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.61 50.0 4.45e-01 96.7% 75.3%
2132714 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.61 49.0 3.97e-01 93.4% 51.2%
4336912 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.60 48.0 4.16e-01 93.4% 54.3%
3946500 306.1.1.1 a+b two layers › Glucose permease domain IIB-like › Glucose permease domain IIB › Glucose permease domain IIB › PTS_EIIB 0.60 49.0 4.65e-01 100.0% 77.5%
4089899 304.120.1.6 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.60 47.0 4.48e-01 91.8% 98.7%
5046135 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.59 49.0 3.70e-01 100.0% 41.2%
3983963 101.1.9.41 alpha arrays › HTH › HTH › Putative DNA-binding domain › ORF6N 0.58 47.0 4.06e-01 93.4% 91.4%
2721400 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 43.0 4.10e-01 80.3% 69.9%
5001428 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.58 47.0 4.49e-01 95.1% 92.0%
5009809 7592.1.1.5 a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › Csx1_CARF 0.58 48.0 3.87e-01 96.7% 86.2%
4181241 109.4.1.2074 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF25873 0.57 40.0 2.36e-01 73.8% 19.1%
4090346 101.1.2.209 alpha arrays › HTH › HTH › winged helix domain › MJ1010-like_2nd 0.57 42.0 4.29e-01 88.5% 83.3%
4936264 2003.1.2.19 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Thi4 0.57 44.0 2.98e-01 88.5% 68.1%
3189627 327.11.2.50 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF26118 0.57 44.0 4.43e-01 85.2% 86.7%
3180169 206.1.2.3 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › IPK 0.57 45.0 2.97e-01 91.8% 84.4%
4957075 101.1.9.134 alpha arrays › HTH › HTH › Putative DNA-binding domain › DUF2067 0.57 44.0 3.85e-01 91.8% 62.9%
None 0.55 37.0 3.15e-01 70.5% 71.8%
3249729 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 39.0 3.65e-01 85.2% 61.3%
2142614 2485.1.1.5 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › AhpC-TSA,1-cysPrx_C 0.54 37.0 2.55e-01 73.8% 74.0%
3420416 101.1.2.245 alpha arrays › HTH › HTH › winged helix domain › PORR 0.53 38.0 3.05e-01 77.0% 47.7%
3666925 101.1.2.386 alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.53 44.0 3.63e-01 100.0% 79.2%
4929751 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 41.0 3.78e-01 90.2% 74.1%
4004341 101.1.2.775 alpha arrays › HTH › HTH › winged helix domain › SieB 0.53 42.0 3.86e-01 90.2% 69.4%
5024398 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.52 39.0 3.18e-01 83.6% 52.3%
3547233 101.1.2.37 alpha arrays › HTH › HTH › winged helix domain › E2F_TDP 0.51 38.0 2.85e-01 85.2% 78.4%
4015761 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 37.0 3.37e-01 83.6% 64.2%
139744 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 40.0 3.52e-01 90.2% 75.3%
2152083 101.1.2.47 alpha arrays › HTH › HTH › winged helix domain › S10_plectin 0.51 39.0 3.51e-01 88.5% 72.8%
3600167 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 38.0 3.21e-01 85.2% 79.1%
D2 medium residues 318-375
PDB
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kafA00 3.90.1150.20 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription regulator MotA, C-terminal domain 0.79 69.0 5.62e-01 98.3% 62.0%
1zhvA00 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.73 63.0 4.90e-01 100.0% 89.6%
7yh1A01 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.72 51.0 4.05e-01 74.1% 99.1%
2fwrA01 3.40.1170.30 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › 0.72 57.0 5.77e-01 100.0% 89.5%
2plgA01 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.71 57.0 4.51e-01 93.1% 72.7%
3dgpA00 3.30.70.2610 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 55.0 5.40e-01 86.2% 88.7%
1zvpD00 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.70 59.0 4.62e-01 98.3% 88.5%
1s7hA02 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 53.0 4.82e-01 86.2% 74.4%
1hi9A02 3.30.1360.130 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Dipeptide transport protein 0.69 59.0 5.47e-01 98.3% 92.1%
2e3tB03 3.30.43.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 0.69 46.0 4.61e-01 70.7% 91.8%
4gvbA00 3.30.70.440 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Killer toxin KP6 alpha-subunit 0.68 53.0 4.91e-01 87.9% 77.9%
2cpqA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.67 49.0 4.83e-01 81.0% 98.4%
3dgpB00 3.30.70.1220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TFB5-like 0.65 50.0 4.93e-01 86.2% 85.7%
3ruyA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.65 52.0 4.05e-01 94.8% 47.6%
3ezjA03 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.64 50.0 5.12e-01 86.2% 98.2%
1ydlA00 3.30.70.1220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TFB5-like 0.63 43.0 4.04e-01 72.4% 69.0%
2i0kA02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.62 44.0 3.52e-01 77.6% 99.2%
2kkhA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 46.0 4.36e-01 86.2% 82.7%
2rdpA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 45.0 3.47e-01 81.0% 41.4%
2xfvA00 3.10.260.30 Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › 0.61 47.0 3.97e-01 87.9% 71.3%
4uhwA03 3.30.43.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 0.61 42.0 4.03e-01 72.4% 82.1%
3c0wA02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.60 49.0 4.19e-01 94.8% 72.8%
3e9lA02 1.20.80.40 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region 0.60 47.0 4.16e-01 93.1% 94.7%
3kzgA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.59 41.0 3.22e-01 72.4% 63.6%
3btxA00 2.60.120.590 Mainly Beta › Sandwich › Jelly Rolls › Alpha-ketoglutarate-dependent dioxygenase AlkB-like 0.59 42.0 2.94e-01 75.9% 85.3%
2r31A01 3.30.2180.10 Alpha Beta › 2-Layer Sandwich › ATP12-like › ATP12-like 0.59 42.0 4.10e-01 100.0% 66.7%
2m8cA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.59 41.0 3.17e-01 72.4% 60.6%
2wteA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 43.0 4.10e-01 81.0% 77.8%
2epcA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.58 31.0 3.65e-01 86.2% 78.8%
1wftA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 49.0 4.13e-01 100.0% 94.2%
1f0jA00 1.10.1300.10 Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 0.56 39.0 2.49e-01 75.9% 50.4%
2ltrA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.56 37.0 3.07e-01 98.3% 38.1%
4zm3B01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 46.0 3.62e-01 100.0% 55.6%
1vx7H01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.55 41.0 3.78e-01 86.2% 89.4%
1yqtA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 44.0 2.95e-01 94.8% 22.4%
5yk4A04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.54 40.0 3.16e-01 82.8% 35.3%
4ig1A00 3.10.520.10 Alpha Beta › Roll › T-fold › ApbE-like domains 0.54 43.0 2.84e-01 100.0% 36.9%
5iroD00 2.60.40.3530 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 46.0 3.87e-01 100.0% 66.7%
7ox5A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 46.0 3.85e-01 100.0% 94.2%
5ttjA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 42.0 3.00e-01 96.6% 75.6%
1dpeA02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.53 37.0 3.02e-01 75.9% 40.3%
1z4hA01 1.10.238.160 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › 0.52 38.0 3.83e-01 81.0% 91.4%
2eodA00 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.51 31.0 2.99e-01 87.9% 51.5%
8dvhB01 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.50 33.0 2.49e-01 70.7% 49.2%
ECOD (65)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3533206 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.88 80.0 7.71e-01 100.0% 93.8%
4966680 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.87 80.0 7.71e-01 100.0% 89.2%
4526098 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.87 79.0 7.03e-01 100.0% 77.5%
3998582 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.87 77.0 7.26e-01 98.3% 87.1%
3936152 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.86 79.0 6.85e-01 100.0% 75.3%
3620127 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.86 78.0 6.96e-01 100.0% 80.0%
3470093 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.86 78.0 7.49e-01 100.0% 93.8%
3409500 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.85 77.0 7.25e-01 100.0% 90.0%
3701635 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.84 75.0 6.33e-01 100.0% 74.7%
5059723 306.3.1.0 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.84 73.0 7.09e-01 96.6% 90.8%
3305375 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.83 76.0 7.09e-01 100.0% 91.4%
3229861 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.83 74.0 6.96e-01 100.0% 92.9%
3252775 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.82 74.0 6.99e-01 100.0% 92.9%
5081376 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.78 67.0 6.29e-01 96.6% 90.0%
4955387 3696.1.1.2 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › XPB_DRD 0.77 57.0 6.04e-01 96.6% 92.0%
5010613 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.77 66.0 6.39e-01 98.3% 92.3%
3970519 327.16.1.10 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system › PF29189 0.77 60.0 6.00e-01 86.2% 95.0%
4028694 306.3.1.0 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.75 66.0 6.43e-01 100.0% 96.9%
4991995 3696.1.1.2 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › XPB_DRD 0.73 62.0 6.00e-01 100.0% 86.2%
3781580 5104.1.1.2 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › CDC45 0.71 61.0 4.89e-01 98.3% 48.7%
5079048 4076.3.1.0 a+b two layers › L9 N-domain-like › GINS/PriA/YqbF domain › GINS/PriA/YqbF domain 0.71 51.0 5.13e-01 84.5% 75.0%
2631980 3696.1.1.2 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › XPB_DRD 0.71 56.0 5.12e-01 100.0% 66.2%
4508402 4340.1.1.0 a+b complex topology › TFB5-related › TFB5-related › TFB5-related 0.70 55.0 5.68e-01 87.9% 98.2%
5064885 2004.1.1.120 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII 0.70 60.0 4.02e-01 100.0% 24.3%
3621547 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.70 61.0 5.92e-01 100.0% 90.8%
3397043 306.5.1.0 a+b two layers › Glucose permease domain IIB-like › GTP cyclohydrolase I feedback regulatory protein, GFRP › GTP cyclohydrolase I feedback regulatory protein, GFRP 0.70 62.0 5.60e-01 100.0% 73.8%
5373 304.50.1.0 a+b two layers › Alpha-beta plaits 0.70 55.0 5.01e-01 87.9% 75.9%
5073020 304.26.1.0 a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like 0.69 52.0 4.48e-01 84.5% 71.7%
4471453 327.16.1.10 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system › PF29189 0.69 54.0 5.35e-01 87.9% 95.0%
5062191 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.68 54.0 5.02e-01 87.9% 74.3%
5018146 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.68 53.0 3.59e-01 89.7% 27.2%
3690781 304.48.1.11 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RNA_pol 0.66 52.0 4.49e-01 87.9% 75.8%
4987556 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.66 56.0 4.94e-01 100.0% 73.3%
5006278 304.7.1.2 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 0.64 47.0 4.80e-01 82.8% 85.5%
379864 101.1.2.135 alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.63 44.0 3.42e-01 74.1% 69.5%
4194607 3016.1.1.10 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › GDC-P 0.63 53.0 5.04e-01 100.0% 95.7%
164037 4340.1.1.1 a+b complex topology › TFB5-related › TFB5-related › TFB5-related › Tfb5 0.63 47.0 4.45e-01 84.5% 75.7%
3661482 4120.1.1.56 few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP › Myb_DNA-bind_3 0.62 42.0 3.84e-01 72.4% 51.2%
4301644 101.19.1.0 alpha arrays › HTH › C-terminal subdomain in oxygen-independent coproporphyrinogen III oxidase HemN › C-terminal subdomain in oxygen-independent coproporphyrinogen III oxidase HemN 0.62 51.0 4.76e-01 100.0% 90.0%
4955639 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.62 51.0 4.97e-01 100.0% 100.0%
4024491 101.1.2.392 alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH 0.61 44.0 3.63e-01 79.3% 74.5%
4507561 3012.1.1.9 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › SecD_1st 0.60 42.0 3.22e-01 77.6% 33.5%
5079289 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.59 44.0 3.67e-01 81.0% 58.1%
3960319 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.59 47.0 3.46e-01 98.3% 31.8%
3946500 306.1.1.1 a+b two layers › Glucose permease domain IIB-like › Glucose permease domain IIB › Glucose permease domain IIB › PTS_EIIB 0.58 46.0 4.29e-01 96.6% 76.2%
3439826 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.57 43.0 3.34e-01 86.2% 82.0%
2097968 101.1.2.4 alpha arrays › HTH › HTH › winged helix domain › Forkhead 0.57 44.0 4.05e-01 87.9% 89.0%
3939505 386.1.1.1 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2 0.56 31.0 3.44e-01 86.2% 65.0%
4244248 210.1.3.2 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › CarA_N 0.54 40.0 2.91e-01 84.5% 74.1%
3511772 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 44.0 4.02e-01 98.3% 94.1%
4014086 109.4.1.777 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 43.0 2.78e-01 93.1% 34.7%
4928214 220.1.1.87 beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_3 0.53 46.0 3.56e-01 100.0% 43.3%
5042767 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 40.0 3.47e-01 86.2% 61.2%
4191632 2003.1.2.38 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Lycopene_cycl 0.53 41.0 2.75e-01 89.7% 46.9%
1834379 101.1.9.0 alpha arrays › HTH › HTH › Putative DNA-binding domain 0.53 40.0 3.94e-01 87.9% 90.9%
3927382 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.52 44.0 2.84e-01 100.0% 70.9%
4250998 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.52 43.0 3.78e-01 98.3% 91.6%
3645693 101.1.2.516 alpha arrays › HTH › HTH › winged helix domain › PF25895 0.52 43.0 3.70e-01 96.6% 73.0%
4014194 4075.1.1.0 a+b complex topology › RGC domain › RGC domain › RGC domain 0.52 36.0 3.08e-01 74.1% 97.0%
5039368 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 40.0 3.70e-01 96.6% 89.4%
4984732 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 41.0 3.74e-01 98.3% 87.5%
5054757 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 38.0 3.17e-01 87.9% 69.9%
5065568 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 40.0 3.20e-01 91.4% 71.5%
3938245 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.51 35.0 2.48e-01 72.4% 86.0%
3181136 4099.1.1.4 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › CENP-O 0.50 41.0 3.30e-01 98.3% 56.9%
D3 medium residues 411-462
PDB
Domain cluster: representative
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.73 49.0 4.59e-01 71.2% 95.4%
2gwlA00 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.71 52.0 3.42e-01 96.2% 20.0%
3bbzA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.71 58.0 6.03e-01 90.4% 100.0%
5f1cA01 1.10.287.940 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel 0.71 50.0 4.83e-01 75.0% 76.3%
3fhnA04 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.69 47.0 3.47e-01 71.2% 29.0%
7wboA01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.68 49.0 3.38e-01 76.9% 26.7%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.66 44.0 4.14e-01 71.2% 59.0%
2a7oA00 1.10.1740.100 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Set2, Rpb1 interacting domain 0.65 53.0 4.32e-01 92.3% 76.0%
5kp7B00 1.10.1200.10 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like 0.64 45.0 3.95e-01 90.4% 49.4%
1nv8B01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.64 51.0 4.77e-01 98.1% 87.3%
2fq3A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 43.0 3.73e-01 88.5% 45.9%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.61 42.0 3.89e-01 71.2% 73.4%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.60 41.0 3.61e-01 71.2% 69.9%
3m03B00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.59 44.0 3.64e-01 82.7% 44.2%
2cqnA00 1.10.10.440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain 0.59 41.0 3.70e-01 76.9% 58.4%
1hwyA01 1.10.287.140 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 41.0 4.17e-01 73.1% 82.4%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 50.0 4.54e-01 100.0% 94.6%
5c9eB01 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.57 43.0 3.61e-01 80.8% 100.0%
3t0yA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 42.0 3.98e-01 88.5% 66.7%
1s4eG02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.57 44.0 3.19e-01 92.3% 29.4%
4gf0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 47.0 3.70e-01 96.2% 72.6%
2cfoA04 1.10.8.70 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutamate-tRNA synthetase, class I, anticodon-binding domain 1 0.56 44.0 4.43e-01 90.4% 90.7%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 40.0 3.44e-01 75.0% 58.4%
4griA04 1.10.8.70 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutamate-tRNA synthetase, class I, anticodon-binding domain 1 0.55 43.0 4.32e-01 90.4% 96.2%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.55 38.0 3.72e-01 73.1% 98.3%
3d6jA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 46.0 4.32e-01 98.1% 76.1%
1hr7C02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.55 45.0 3.07e-01 100.0% 75.6%
1x9fC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 46.0 3.39e-01 100.0% 55.7%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.52 39.0 3.60e-01 78.8% 90.6%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3258045 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.75 54.0 3.34e-01 75.0% 15.3%
3267780 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.70 50.0 3.09e-01 75.0% 14.3%
3642338 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.68 46.0 4.06e-01 71.2% 64.0%
3510680 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.68 49.0 4.45e-01 76.9% 74.3%
4959086 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.67 45.0 4.05e-01 71.2% 93.3%
3622487 604.7.1.1 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA 0.64 59.0 4.52e-01 100.0% 96.4%
5018716 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.62 42.0 3.78e-01 71.2% 77.1%
4167208 604.15.1.0 alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like 0.61 44.0 4.23e-01 76.9% 66.7%
4927627 148.1.3.19 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 0.59 51.0 4.13e-01 100.0% 68.6%
4609007 101.1.17.0 alpha arrays › HTH › HTH › FF domain 0.59 40.0 4.13e-01 71.2% 74.0%
4322551 604.23.1.0 alpha bundles › Spectrin repeat-like › Sbi complement-binding domain › Sbi complement-binding domain 0.59 43.0 4.27e-01 76.9% 72.7%
3230586 7022.1.1.1 alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › MBOAT 0.58 47.0 3.18e-01 90.4% 33.0%
3624011 101.1.1.76 alpha arrays › HTH › HTH › Three-helical HTH › Integrase_H2C2 0.58 45.0 3.20e-01 88.5% 32.9%
3503635 605.1.1.133 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › OST3_OST6 0.57 46.0 3.49e-01 88.5% 47.5%
3781056 4156.1.1.4 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C 0.57 43.0 3.07e-01 100.0% 29.0%
3702686 3525.1.1.0 alpha arrays › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain 0.55 47.0 4.41e-01 98.1% 98.5%
3592511 3525.1.1.0 alpha arrays › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain 0.54 43.0 4.10e-01 96.2% 95.4%
3631175 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 43.0 2.67e-01 88.5% 25.9%
4092726 2003.1.2.8 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_2,Pyr_redox_2 0.53 47.0 3.08e-01 98.1% 80.0%
D4 medium residues 463-578
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1szhA02 1.10.150.370 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Caenorhabditis elegans Her-1, C-terminal domain 0.70 33.0 3.84e-01 94.0% 61.0%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.67 41.0 3.23e-01 84.5% 31.7%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 46.0 3.62e-01 81.0% 94.5%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.58 36.0 4.24e-01 83.6% 94.7%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.58 39.0 3.64e-01 81.9% 55.6%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.58 41.0 4.35e-01 83.6% 81.9%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.57 45.0 4.84e-01 100.0% 99.0%
1yjgA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.56 43.0 3.92e-01 81.9% 100.0%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 42.0 4.06e-01 80.2% 100.0%
2e87A01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 40.0 3.64e-01 84.5% 56.2%
7sf8A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 40.0 3.17e-01 76.7% 85.9%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.52 38.0 3.92e-01 76.7% 100.0%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 44.0 4.52e-01 94.0% 98.2%
1st6A02 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.50 42.0 3.38e-01 91.4% 74.2%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.50 33.0 3.84e-01 94.8% 95.1%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4973614 5069.1.3.26 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF1622 0.68 43.0 4.47e-01 87.9% 68.2%
1313624 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.65 40.0 3.48e-01 83.6% 42.5%
4951992 5041.1.1.55 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › DUF1622 0.64 42.0 4.56e-01 87.9% 79.0%
4430792 192.29.1.52 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy 0.62 48.0 4.22e-01 80.2% 99.4%
3697356 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 39.0 4.50e-01 90.5% 85.9%
3419627 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.60 45.0 4.16e-01 80.2% 94.0%
3965374 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 37.0 3.21e-01 89.7% 40.0%
3240217 603.1.1.105 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 0.58 41.0 4.49e-01 87.9% 88.4%
3710228 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 43.0 4.13e-01 79.3% 97.8%
3272618 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.57 43.0 3.88e-01 79.3% 85.8%
3215510 601.16.1.0 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.56 41.0 3.88e-01 92.2% 63.6%
5009576 5069.1.1.105 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF973 0.56 46.0 3.86e-01 93.1% 52.8%
5023516 3922.1.1.269 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Rad50_zn_hook 0.54 44.0 3.39e-01 83.6% 59.6%
3574330 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 36.0 3.70e-01 87.1% 69.6%
4944887 101.1.1.546 alpha arrays › HTH › HTH › Three-helical HTH › ThiN 0.53 34.0 3.45e-01 94.8% 64.2%
5042399 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.53 46.0 3.56e-01 93.1% 83.7%
3620191 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.52 41.0 3.36e-01 83.6% 83.8%
3787270 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.51 46.0 3.68e-01 99.1% 50.4%
3287147 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.51 41.0 3.59e-01 85.3% 81.2%