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IMGVR_UViG_3300049638_000916-3300049638-Ga0499516_015062_462_3401

Arc-Vir

IMGVR_UViG_3300049638_000916-3300049638-Ga0499516_015062_462_3401

Quality

83.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 230-326
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF22763.2 best NrS1-1_pol-like_HBD 65.4 4.70e-18 60.8% 85.9%
D2 high residues 348-468
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06048.18 best DUF927 39.5 7.50e-10 93.4% 35.6%
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3be3A00 2.30.30.320 Mainly Beta › Roll › SH3 type barrels. › DUF1653-like domain 0.61 35.0 4.25e-01 82.6% 88.2%
1wznA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.59 24.0 3.44e-01 73.6% 80.4%
3wa5B00 2.60.120.1690 Mainly Beta › Sandwich › Jelly Rolls › 0.57 33.0 3.27e-01 74.4% 53.2%
7kx7A03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.56 39.0 3.27e-01 71.9% 100.0%
2l73A00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.53 38.0 3.59e-01 72.7% 88.8%
3iq2A00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.53 37.0 3.74e-01 83.5% 71.5%
2d42A02 3.10.450.380 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 28.0 3.69e-01 84.3% 96.9%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.52 43.0 4.15e-01 90.9% 95.7%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018480 1104.1.1.0 a+b complex topology › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain 0.92 88.0 7.48e-01 100.0% 69.4%
3975472 1104.1.1.1 a+b complex topology › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain › DUF927 0.85 79.0 7.17e-01 99.2% 76.8%
3948387 1104.1.1.1 a+b complex topology › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain › DUF927 0.81 71.0 6.57e-01 95.9% 74.7%
3769980 284.1.3.4 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › CCTL2_WNK 0.69 43.0 4.92e-01 84.3% 84.4%
3328840 284.1.2.0 a+b two layers › FKBP-like › FKBP-like › Conserved carboxy-terminal domain of oxidative-stress-responsive kinase 1-like kinases 0.69 43.0 5.06e-01 84.3% 90.6%
3342794 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.64 45.0 5.06e-01 73.6% 100.0%
3819740 284.1.3.4 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › CCTL2_WNK 0.63 43.0 4.84e-01 93.4% 94.4%
3805804 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.63 43.0 4.90e-01 92.6% 98.8%
331968 4.1.1.55 beta barrels › SH3 › SH3 › SH3 › DUF1653 0.61 35.0 4.20e-01 82.6% 85.9%
3880705 277.1.1.0 a+b two layers › PX domain › PX domain › PX domain 0.58 41.0 4.06e-01 71.9% 96.0%
3744517 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.57 39.0 3.95e-01 86.0% 70.0%
3709548 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.57 37.0 3.65e-01 86.0% 61.5%
3914347 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.56 40.0 3.83e-01 71.9% 97.0%
3669779 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.56 40.0 3.79e-01 72.7% 97.9%
3278704 4210.1.1.0 a+b two layers › WGR domain › WGR domain › WGR domain 0.56 36.0 4.25e-01 88.4% 100.0%
3546312 277.1.1.0 a+b two layers › PX domain › PX domain › PX domain 0.55 39.0 4.15e-01 72.7% 100.0%
3232594 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.55 49.0 4.03e-01 97.5% 57.3%
4989633 3891.1.1.0 a+b two layers › Archaea-specific ribosomal protein L46a › Archaea-specific ribosomal protein L46a › Archaea-specific ribosomal protein L46a 0.53 34.0 4.16e-01 72.7% 98.8%
3412288 298.1.1.6 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › G6PD_C 0.53 38.0 2.87e-01 75.2% 63.2%
3889863 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.53 37.0 3.74e-01 71.1% 100.0%
4810631 2003.1.2.18 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.52 46.0 3.37e-01 97.5% 95.7%
4653150 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.52 33.0 3.48e-01 74.4% 70.9%
4422553 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.51 37.0 2.33e-01 94.2% 14.0%
3723968 2003.1.2.65 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FMO-like, Pyr_redox_3 0.50 44.0 3.05e-01 96.7% 82.6%
D3 high residues 779-900
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF18662.8 best HTH_56 27.3 4.20e-06 95.1% 82.9%
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4gyiA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 46.0 5.15e-01 100.0% 77.4%
4hqeA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 43.0 4.66e-01 100.0% 67.6%
1stzA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 42.0 4.89e-01 100.0% 82.4%
2hoeA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 35.0 4.89e-01 91.0% 100.0%
5eriA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 40.0 3.74e-01 100.0% 44.4%
2l2oA00 1.10.10.1540 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Costar domain 0.69 45.0 5.22e-01 100.0% 92.9%
4rayA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 39.0 4.53e-01 95.1% 78.8%
2v9vA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 38.0 4.82e-01 93.4% 95.7%
5hs7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 40.0 4.46e-01 100.0% 73.5%
3c18A03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.67 33.0 4.56e-01 85.2% 100.0%
5dymA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.67 42.0 4.62e-01 100.0% 79.2%
4esbA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 42.0 4.48e-01 100.0% 75.7%
1ub9A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 41.0 4.47e-01 100.0% 77.0%
3l7wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 42.0 4.47e-01 100.0% 75.2%
1vtnC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 42.0 4.59e-01 100.0% 79.4%
4ejoA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 39.0 4.06e-01 100.0% 64.3%
2mlgA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 36.0 4.33e-01 95.1% 84.4%
6kf9G01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 37.0 4.40e-01 98.4% 85.4%
5h20A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 39.0 4.21e-01 100.0% 72.8%
1z7uB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 40.0 4.18e-01 100.0% 70.0%
2eshA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 40.0 4.17e-01 100.0% 69.3%
4y66F01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 33.0 4.30e-01 92.6% 95.5%
6abqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 40.0 4.26e-01 100.0% 74.5%
3r0aA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 38.0 3.88e-01 100.0% 62.5%
2dqlA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 41.0 4.22e-01 100.0% 72.2%
3elkA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 40.0 4.27e-01 100.0% 77.1%
1sfxB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 37.0 3.99e-01 99.2% 71.2%
5hvqC01 3.90.1150.220 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.60 38.0 4.52e-01 95.9% 97.5%
2p4wA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 37.0 3.97e-01 100.0% 72.8%
1kyzA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 38.0 4.09e-01 100.0% 79.6%
1itpA00 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.54 26.0 3.18e-01 87.7% 70.1%
1fpqA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.91e-01 100.0% 73.6%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018482 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.84 65.0 7.18e-01 100.0% 98.0%
3938065 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.76 46.0 5.66e-01 95.1% 97.3%
4015761 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.75 45.0 5.00e-01 100.0% 75.8%
5043135 101.1.2.26 alpha arrays › HTH › HTH › winged helix domain › HxlR 0.73 43.0 4.84e-01 100.0% 74.7%
4997255 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.72 46.0 5.04e-01 100.0% 78.0%
3948523 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.71 42.0 5.25e-01 95.1% 100.0%
5071263 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.70 44.0 5.02e-01 100.0% 85.6%
4991088 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 38.0 4.51e-01 95.1% 82.5%
3944118 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.67 41.0 4.65e-01 100.0% 81.1%
5027611 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.66 37.0 4.48e-01 95.9% 86.7%
5082509 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.66 42.0 4.12e-01 100.0% 60.0%
4932062 101.1.2.26 alpha arrays › HTH › HTH › winged helix domain › HxlR 0.65 42.0 4.59e-01 100.0% 79.0%
4949226 101.1.2.892 alpha arrays › HTH › HTH › winged helix domain › ArsR 0.65 39.0 3.53e-01 99.2% 44.4%
5075002 101.1.2.525 alpha arrays › HTH › HTH › winged helix domain › DUF7646 0.64 37.0 4.15e-01 99.2% 72.6%
5073878 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.64 36.0 4.51e-01 93.4% 94.3%
3412336 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.64 38.0 4.53e-01 93.4% 85.9%
5032312 101.1.2.271 alpha arrays › HTH › HTH › winged helix domain › B-block_TFIIIC 0.64 37.0 3.91e-01 98.4% 62.7%
5011468 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.64 38.0 3.85e-01 99.2% 58.4%
5050784 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.64 42.0 4.83e-01 99.2% 92.2%
4950221 101.1.2.143 alpha arrays › HTH › HTH › winged helix domain › HTH_34 0.63 41.0 4.33e-01 100.0% 73.1%
4985036 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.63 37.0 3.29e-01 99.2% 40.6%
4995959 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.63 37.0 3.89e-01 95.1% 63.6%
5054938 101.1.2.271 alpha arrays › HTH › HTH › winged helix domain › B-block_TFIIIC 0.62 37.0 3.77e-01 98.4% 58.8%
4979651 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.62 37.0 4.22e-01 97.5% 78.9%
4959073 101.1.2.271 alpha arrays › HTH › HTH › winged helix domain › B-block_TFIIIC 0.62 37.0 3.80e-01 97.5% 59.2%
5007541 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.62 36.0 3.92e-01 99.2% 67.6%
2391543 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.62 41.0 3.53e-01 100.0% 41.6%
3700393 101.1.2.82 alpha arrays › HTH › HTH › winged helix domain › TBPIP 0.62 36.0 3.01e-01 95.9% 32.1%
3741066 101.1.2.86 alpha arrays › HTH › HTH › winged helix domain › SMC_Nse1 0.61 38.0 4.48e-01 95.1% 92.5%
4998580 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.61 38.0 4.35e-01 100.0% 84.4%
5032906 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.60 40.0 3.87e-01 99.2% 59.3%
3446454 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.60 37.0 4.31e-01 97.5% 92.5%
5054122 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.59 38.0 3.48e-01 100.0% 48.8%
4947925 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.59 35.0 3.23e-01 99.2% 44.2%
5055444 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.59 37.0 4.02e-01 100.0% 76.0%
5031648 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.59 36.0 3.28e-01 99.2% 44.2%
5042462 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.58 37.0 3.34e-01 99.2% 46.7%
4403519 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.57 37.0 3.30e-01 99.2% 45.9%
5082704 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.57 39.0 3.29e-01 99.2% 42.6%
4958997 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.57 37.0 4.22e-01 99.2% 88.9%
4943395 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.57 37.0 3.30e-01 99.2% 46.5%
5014384 101.1.2.54 alpha arrays › HTH › HTH › winged helix domain › Penicillinase_R 0.56 38.0 3.93e-01 100.0% 72.2%
3667109 101.1.2.111 alpha arrays › HTH › HTH › winged helix domain › RQC 0.56 43.0 4.31e-01 100.0% 80.0%
3968103 101.1.2.100 alpha arrays › HTH › HTH › winged helix domain › FeoC 0.55 36.0 4.31e-01 93.4% 100.0%
3615178 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.55 42.0 3.67e-01 100.0% 53.5%
4646072 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.55 36.0 3.24e-01 99.2% 48.2%
3840298 101.1.2.394 alpha arrays › HTH › HTH › winged helix domain › eWH_GTF3C1 0.54 36.0 3.57e-01 95.9% 63.1%
4940657 101.1.2.269 alpha arrays › HTH › HTH › winged helix domain › SocA_Panacea 0.52 40.0 3.66e-01 100.0% 61.0%
4585912 101.1.2.603 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9 0.51 40.0 2.82e-01 98.4% 27.2%
D4 medium residues 26-111
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kxtA00 2.30.30.610 Mainly Beta › Roll › SH3 type barrels. › Chromatin protein Cren7 0.54 27.0 3.15e-01 80.2% 67.9%
4jp0A01 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.53 43.0 3.70e-01 90.7% 98.6%
2xzhA00 2.130.10.110 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Clathrin heavy-chain terminal domain 0.51 41.0 2.76e-01 88.4% 67.3%
2rovA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.50 33.0 3.00e-01 87.2% 48.7%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3460576 109.3.1.162 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_5 0.56 42.0 3.03e-01 80.2% 33.5%
3479868 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.56 35.0 3.50e-01 82.6% 60.0%
3650875 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.55 41.0 2.79e-01 80.2% 87.0%
3258610 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.50 33.0 3.43e-01 74.4% 71.2%
3511551 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.50 30.0 3.53e-01 73.3% 86.7%
3597380 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.50 36.0 3.28e-01 76.7% 80.0%
D5 medium residues 112-218
PDB
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2hw0A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.60 49.0 4.79e-01 86.9% 88.7%
3hh7A00 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.60 28.0 3.45e-01 71.0% 70.8%
2atzA00 3.90.920.20 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › HP0184-like 0.59 47.0 4.04e-01 86.9% 61.4%
1qm9A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 43.0 4.50e-01 77.6% 100.0%
2cg8B02 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.59 44.0 4.12e-01 79.4% 86.4%
1f08B00 3.40.1310.10 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.58 47.0 4.27e-01 86.9% 77.2%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.58 40.0 3.45e-01 70.1% 55.7%
1qupA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 34.0 3.94e-01 94.4% 85.7%
1sjrA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 45.0 4.53e-01 85.0% 93.5%
2vfrA03 3.30.70.2530 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 37.0 4.02e-01 71.0% 80.5%
5yppA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.57 39.0 4.14e-01 70.1% 95.6%
2rhqB06 3.30.70.380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ferrodoxin-fold anticodon-binding domain 0.56 37.0 4.14e-01 91.6% 88.0%
6h8oA00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.55 45.0 4.71e-01 86.9% 100.0%
1r9wA00 3.40.1310.10 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.55 43.0 4.00e-01 85.0% 76.8%
2j5aA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.55 42.0 4.28e-01 83.2% 100.0%
4pg4B03 3.30.70.3100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 37.0 4.27e-01 81.3% 98.7%
3wdoA02 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 30.0 3.69e-01 90.7% 91.8%
3n79A01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.54 38.0 4.34e-01 79.4% 100.0%
3to8A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.53 43.0 4.39e-01 86.9% 99.0%
4rl1A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.53 34.0 4.00e-01 71.0% 98.6%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.53 36.0 3.44e-01 70.1% 79.2%
3pm9A04 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 35.0 3.78e-01 91.6% 81.6%
3gk6A00 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.53 39.0 3.48e-01 77.6% 82.4%
3mk6B01 3.30.420.510 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.52 38.0 3.45e-01 77.6% 84.3%
4gvbB00 3.30.70.440 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Killer toxin KP6 alpha-subunit 0.52 32.0 3.70e-01 94.4% 87.8%
3ba3B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.51 36.0 3.38e-01 73.8% 79.0%
2b4vA03 3.30.70.1970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 35.0 3.69e-01 71.0% 92.9%
3e3xA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 38.0 4.05e-01 89.7% 91.5%
1yqhA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 36.0 3.72e-01 73.8% 96.2%
4oj3B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 40.0 4.21e-01 86.9% 94.7%
6vh5C03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.50 37.0 4.02e-01 78.5% 100.0%
5xbtA01 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.50 37.0 3.37e-01 77.6% 83.0%
4wiqA02 3.30.70.1040 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dystroglycan, domain 2 0.50 37.0 3.59e-01 79.4% 94.4%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4962598 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.90 80.0 6.62e-01 97.2% 58.2%
4959587 862.1.1.3 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › Prim-Pol 0.68 60.0 5.09e-01 94.4% 64.7%
4416349 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.61 38.0 4.27e-01 94.4% 83.7%
5047432 304.8.1.4 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.61 41.0 4.47e-01 70.1% 95.6%
3593320 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.60 41.0 4.54e-01 70.1% 100.0%
3672141 304.162.1.0 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.59 35.0 4.15e-01 92.5% 90.0%
3236477 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.59 41.0 3.88e-01 72.0% 67.7%
4982458 304.162.1.2 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › FLAD1_M 0.58 35.0 4.15e-01 93.5% 91.4%
3876216 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.58 41.0 4.15e-01 72.9% 81.9%
5083386 304.12.1.0 a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 0.58 40.0 4.20e-01 71.0% 90.5%
3419617 304.9.1.85 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF28947 0.58 39.0 4.24e-01 70.1% 97.8%
3648905 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.57 39.0 3.66e-01 70.1% 88.5%
2832043 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.57 41.0 4.10e-01 75.7% 78.6%
3482851 304.9.1.23 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_5 0.56 44.0 4.28e-01 86.0% 87.5%
3297757 390.1.1.6 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_2 0.55 33.0 3.74e-01 75.7% 78.8%
1646873 304.6.1.2 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › ALO 0.55 41.0 3.17e-01 78.5% 58.9%
3273114 304.9.1.23 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_5 0.55 42.0 4.05e-01 81.3% 80.0%
3936048 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.55 38.0 4.05e-01 71.0% 92.5%
5002191 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.55 37.0 4.06e-01 72.0% 88.2%
4026778 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.54 36.0 4.06e-01 100.0% 90.0%
1553952 304.8.1.19 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › HSD_C 0.54 37.0 4.24e-01 83.2% 98.7%
3570820 304.112.1.10 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain › Med13_N 0.53 42.0 3.42e-01 85.0% 85.5%
4967469 304.110.1.1 a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase 0.53 41.0 4.00e-01 79.4% 98.3%
5051761 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.53 39.0 4.26e-01 81.3% 93.3%
3371203 304.9.1.20 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_8 0.53 42.0 4.33e-01 86.0% 99.0%
3626328 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.53 37.0 4.14e-01 79.4% 96.2%
4987909 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.53 39.0 4.16e-01 79.4% 89.5%
5044656 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.53 46.0 4.40e-01 98.1% 96.0%
5056439 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.52 40.0 4.18e-01 81.3% 90.5%
5010338 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.52 40.0 3.92e-01 82.2% 95.7%
4929978 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.51 39.0 4.02e-01 81.3% 86.0%
1556730 304.8.1.19 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › HSD_C 0.51 35.0 3.66e-01 81.3% 80.4%
4156195 304.110.1.1 a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase 0.51 37.0 3.88e-01 77.6% 93.9%
5042490 304.110.1.1 a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase 0.51 39.0 4.06e-01 85.0% 88.0%
5016775 304.122.1.1 a+b two layers › Alpha-beta plaits › Nitrogen repressor-like proteins › Nitrogen repressor-like proteins › NRD1_2 0.51 39.0 3.98e-01 82.2% 89.5%
3186904 304.110.1.1 a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase 0.51 39.0 4.19e-01 85.0% 95.7%
D6 medium residues 509-552_586-613_637-667
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7mcsC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.72 57.0 4.53e-01 85.4% 99.1%
2qbyB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 56.0 4.68e-01 89.3% 97.7%
4tvsA00 3.40.50.12190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.67 58.0 4.59e-01 98.1% 88.4%
1tueD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 60.0 4.80e-01 100.0% 76.2%
3vkgA05 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 51.0 4.51e-01 86.4% 97.3%
3vkgA07 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 55.0 3.68e-01 96.1% 44.7%
2gnoA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 50.0 4.53e-01 85.4% 97.8%
2r44A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 52.0 4.42e-01 91.3% 91.0%
3vkhB09 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 52.0 4.36e-01 97.1% 97.3%
3nbxX01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 51.0 4.06e-01 97.1% 71.3%
3pvsB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 51.0 4.51e-01 100.0% 94.0%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 45.0 3.50e-01 84.5% 68.2%
1wp9A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 50.0 4.04e-01 98.1% 93.5%
3zh9B01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 43.0 3.91e-01 85.4% 83.2%
1mabA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 45.0 3.29e-01 91.3% 70.6%
8ouzD01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 42.0 3.37e-01 88.3% 62.9%
2ihuA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.53 42.0 3.52e-01 86.4% 85.4%
4dg8A01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.53 47.0 3.17e-01 99.0% 73.0%
1booA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 40.0 2.93e-01 80.6% 99.3%
4azsA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 45.0 3.62e-01 100.0% 91.8%
4xcvA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 42.0 3.50e-01 89.3% 99.5%
2uyoA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 42.0 3.23e-01 94.2% 93.5%
2ppwA00 3.40.1400.10 Alpha Beta › 3-Layer(aba) Sandwich › Ribose 5-phosphate Isomerase B; Chain: A, › Sugar-phosphate isomerase, RpiB/LacA/LacB 0.51 38.0 3.04e-01 78.6% 61.0%
3hwwA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.51 42.0 3.37e-01 90.3% 81.9%
3tw8A02 3.40.50.11500 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › DENN domain, C-terminal lobe 0.50 43.0 3.80e-01 99.0% 65.9%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018481 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.93 89.0 6.20e-01 100.0% 57.2%
1883334 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.86 81.0 5.80e-01 100.0% 59.6%
4869672 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.78 73.0 5.48e-01 98.1% 54.3%
3292397 2004.1.1.135 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PIF1 0.68 61.0 4.55e-01 100.0% 56.5%
9753 2004.1.1.48 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PPV_E1_C 0.67 61.0 4.86e-01 100.0% 74.6%
4964454 2004.1.1.196 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 0.67 59.0 4.79e-01 96.1% 88.4%
3938925 2004.1.1.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.65 59.0 5.13e-01 100.0% 91.6%
4132348 2004.1.1.196 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 0.63 53.0 4.33e-01 96.1% 86.8%
4944736 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 53.0 4.11e-01 93.2% 73.0%
3712546 2004.1.1.181 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_7 0.62 50.0 4.22e-01 89.3% 97.8%
5036693 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.61 54.0 4.47e-01 98.1% 90.8%
3839744 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 53.0 4.01e-01 98.1% 71.7%
5015090 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.61 54.0 3.83e-01 98.1% 99.0%
5006613 2004.1.1.120 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII 0.61 53.0 3.50e-01 99.0% 49.8%
None 0.61 55.0 4.73e-01 100.0% 98.8%
3922834 2004.1.1.180 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_6 0.61 54.0 4.39e-01 100.0% 78.0%
3708220 2004.1.1.181 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_7 0.59 51.0 4.17e-01 97.1% 94.0%
3937233 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 50.0 4.38e-01 94.2% 88.7%
3702069 2004.1.1.181 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_7 0.59 50.0 4.05e-01 97.1% 82.2%
4966543 2004.1.1.196 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 0.58 51.0 4.18e-01 100.0% 91.5%
4039588 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.57 51.0 4.29e-01 100.0% 87.2%
5057947 2004.1.1.175 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ParA 0.57 44.0 3.45e-01 84.5% 65.4%
4027018 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 48.0 3.08e-01 95.1% 48.9%
3385549 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.53 42.0 3.42e-01 85.4% 89.2%
2756921 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.52 42.0 3.39e-01 91.3% 80.1%
4177291 7510.1.1.5 a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › PdxA 0.51 40.0 3.31e-01 86.4% 57.4%
D7 medium residues 553-585_668-692
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4qozC00 1.10.8.1120 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Histone RNA hairpin-binding protein RNA-binding domain 0.53 44.0 4.12e-01 96.6% 90.4%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3425013 101.1.1.65 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4 0.55 44.0 3.33e-01 93.1% 93.3%
4983940 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.52 40.0 3.08e-01 84.5% 36.3%
D8 medium residues 693-778
PDB
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fouA01 1.10.246.30 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.73 57.0 6.08e-01 82.6% 100.0%
1n5uA02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.72 55.0 5.45e-01 83.7% 77.8%
1ad6A00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.70 61.0 4.76e-01 96.5% 60.5%
1sgmA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.69 54.0 4.17e-01 82.6% 46.2%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.66 55.0 4.56e-01 91.9% 65.4%
2np3A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 51.0 4.35e-01 86.0% 53.5%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 45.0 4.08e-01 73.3% 68.1%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 46.0 4.09e-01 76.7% 68.5%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.63 43.0 4.36e-01 73.3% 70.9%
5nx5B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.63 52.0 3.59e-01 90.7% 50.7%
2c0uA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 43.0 3.44e-01 72.1% 53.8%
3umbA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.61 42.0 4.40e-01 70.9% 84.8%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 45.0 4.04e-01 77.9% 84.4%
1x42A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.61 44.0 4.47e-01 76.7% 80.7%
2ly8A00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.61 46.0 4.18e-01 82.6% 81.0%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.60 48.0 3.96e-01 87.2% 93.7%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.60 44.0 4.18e-01 77.9% 72.8%
1h99A02 1.10.1790.10 Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › PRD domain 0.59 45.0 4.24e-01 82.6% 99.1%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 46.0 3.96e-01 84.9% 53.7%
3t9oB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.58 46.0 4.10e-01 83.7% 65.8%
3i1aA03 1.20.58.840 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 43.0 3.94e-01 80.2% 95.7%
2ibdA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 45.0 3.77e-01 86.0% 60.5%
2pbeA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 48.0 4.23e-01 94.2% 99.2%
4c91A03 1.20.58.2150 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 46.0 3.68e-01 90.7% 54.7%
1gcvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 41.0 3.49e-01 79.1% 58.6%
8b9zK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 46.0 4.61e-01 96.5% 92.3%
5cy5B00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.54 47.0 3.94e-01 96.5% 95.3%
4f91B04 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.54 42.0 3.60e-01 84.9% 100.0%
1vt0k00 1.10.3230.20 Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › P22 tail accessory factor (Gp4) 0.53 44.0 3.82e-01 95.3% 69.0%
4f92B10 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.53 42.0 3.57e-01 86.0% 99.3%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 44.0 3.69e-01 94.2% 69.7%
2jbyA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.52 37.0 3.26e-01 74.4% 66.9%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018481 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.94 88.0 5.86e-01 97.7% 33.3%
1883334 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.83 76.0 5.19e-01 100.0% 31.5%
3517388 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.80 73.0 5.52e-01 100.0% 45.1%
3944606 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.78 70.0 4.80e-01 98.8% 29.8%
3388455 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.67 52.0 4.74e-01 82.6% 79.1%
5048730 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.67 50.0 4.05e-01 81.4% 64.7%
3708859 633.24.1.0 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain 0.66 46.0 4.29e-01 70.9% 73.3%
5068844 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.65 45.0 4.41e-01 72.1% 72.6%
3588332 5069.1.1.23 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF2798 0.65 49.0 4.26e-01 82.6% 67.9%
3880538 632.1.1.28 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DUF2678 0.65 46.0 4.64e-01 74.4% 91.8%
5078783 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.65 51.0 4.78e-01 84.9% 83.8%
3189791 601.19.1.18 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Mmc1_C 0.64 51.0 3.78e-01 87.2% 70.4%
4978937 3447.1.1.4 alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › PEMT 0.64 56.0 4.39e-01 100.0% 61.1%
5070523 4044.1.1.0 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.63 47.0 4.55e-01 77.9% 78.9%
5045079 1076.1.1.1 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.62 53.0 3.74e-01 96.5% 88.6%
3508265 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.62 54.0 3.59e-01 100.0% 71.5%
3573589 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.61 43.0 4.08e-01 72.1% 82.0%
5051430 632.1.1.2 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › BE_C 0.61 43.0 3.91e-01 74.4% 75.0%
5081551 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.61 51.0 3.49e-01 93.0% 47.5%
3946572 5001.1.1.15 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TMR-DISM_7TM 0.60 46.0 3.45e-01 82.6% 44.9%
3598386 606.1.1.0 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain 0.60 44.0 3.83e-01 77.9% 57.8%
4150867 5058.1.1.29 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › AlaE 0.60 48.0 4.66e-01 87.2% 80.0%
4040950 3843.1.1.4 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB 0.59 51.0 4.65e-01 94.2% 81.4%
4467968 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.59 44.0 3.92e-01 76.7% 61.7%
3549992 7004.1.1.0 0.59 44.0 4.08e-01 80.2% 90.1%
4088719 3579.1.1.13 extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › PhaG_MnhG_YufB 0.59 50.0 4.60e-01 94.2% 81.4%
3585701 7512.1.1.18 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycogen_syn 0.58 51.0 3.72e-01 100.0% 85.9%
4090469 604.12.1.49 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › CrtO 0.58 49.0 4.35e-01 96.5% 88.5%
4480963 3843.1.1.4 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB 0.57 48.0 4.50e-01 91.9% 82.9%
3968410 3843.1.1.4 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB 0.57 49.0 4.68e-01 95.3% 97.0%
3988974 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.56 45.0 4.17e-01 87.2% 81.8%
4024013 4954.1.1.1 a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 0.56 40.0 3.02e-01 77.9% 41.3%
3717238 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.55 45.0 4.42e-01 91.9% 95.8%
4085263 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.54 37.0 3.56e-01 70.9% 64.0%
5076088 5039.1.1.0 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like 0.53 40.0 3.43e-01 79.1% 64.4%
3997950 5069.1.3.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › GOST_TM 0.53 43.0 4.24e-01 87.2% 93.3%
5029691 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.52 43.0 3.75e-01 90.7% 82.2%
4023225 3924.1.1.0 alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 0.52 43.0 3.04e-01 93.0% 27.6%
3945095 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.52 44.0 4.19e-01 96.5% 94.3%
3273576 5001.1.1.31 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM 0.51 46.0 3.26e-01 98.8% 47.8%