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IMGVR_UViG_3300049740_002919-3300049740-Ga0494453_0024120_38_658
Arc-VirIMGVR_UViG_3300049740_002919-3300049740-Ga0494453_0024120_38_658
Identity
- Kingdom:
- archaea
Quality
88.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-112
Domain cluster:
representative
CATH (46)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.74 | 46.0 | 4.74e-01 | 91.1% | 64.2% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 57.0 | 5.50e-01 | 89.3% | 73.2% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 60.0 | 6.19e-01 | 91.1% | 95.2% |
| 4od8D00 | 6.10.140.1880 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 35.0 | 4.86e-01 | 88.4% | 100.0% |
| 3k3oA02 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 48.0 | 5.43e-01 | 91.1% | 91.7% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.70 | 49.0 | 5.42e-01 | 90.2% | 90.9% |
| 8h6rA01 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.70 | 47.0 | 5.31e-01 | 89.3% | 89.4% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.69 | 50.0 | 5.00e-01 | 92.9% | 73.0% |
| 1bf5A01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.69 | 60.0 | 5.23e-01 | 95.5% | 92.3% |
| 3evyA00 | 1.20.58.910 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 46.0 | 5.25e-01 | 91.1% | 95.2% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.67 | 57.0 | 5.01e-01 | 92.0% | 70.6% |
| 3zliA02 | 1.20.58.1370 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 37.0 | 4.15e-01 | 89.3% | 69.4% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 47.0 | 4.77e-01 | 96.4% | 72.6% |
| 3uonA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 57.0 | 4.24e-01 | 92.9% | 79.9% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 51.0 | 5.44e-01 | 92.0% | 95.9% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.65 | 54.0 | 5.64e-01 | 94.6% | 98.0% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.64 | 43.0 | 4.31e-01 | 90.2% | 66.1% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 47.0 | 4.64e-01 | 92.0% | 73.5% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.64 | 48.0 | 4.50e-01 | 92.9% | 65.0% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.63 | 55.0 | 4.81e-01 | 95.5% | 75.3% |
| 2gsqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 48.0 | 4.92e-01 | 95.5% | 86.1% |
| 8f76A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 53.0 | 3.93e-01 | 93.8% | 74.6% |
| 2fbnA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 42.0 | 3.82e-01 | 95.5% | 51.0% |
| 2wauA02 | 1.20.58.830 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 52.0 | 5.07e-01 | 92.0% | 95.9% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.62 | 52.0 | 4.92e-01 | 92.9% | 76.3% |
| 5dqqA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.62 | 47.0 | 4.51e-01 | 92.9% | 69.5% |
| 3cbuA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 46.0 | 4.37e-01 | 92.9% | 66.4% |
| 5yixA00 | 1.10.601.10 | Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor | 0.61 | 46.0 | 3.38e-01 | 80.4% | 70.1% |
| 6w08A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.61 | 52.0 | 3.69e-01 | 92.9% | 69.4% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 51.0 | 4.75e-01 | 92.0% | 90.3% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 48.0 | 4.93e-01 | 85.7% | 95.3% |
| 1s05A00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.60 | 48.0 | 4.60e-01 | 92.9% | 73.6% |
| 4agsB04 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 44.0 | 4.19e-01 | 93.8% | 65.4% |
| 4p3gD00 | 1.10.3450.40 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › Signal recognition particle, SRP68 subunit, RNA-binding domain | 0.59 | 51.0 | 4.27e-01 | 95.5% | 55.4% |
| 3vadA01 | 1.20.140.20 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain | 0.58 | 48.0 | 4.31e-01 | 96.4% | 64.1% |
| 3t5vA00 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.57 | 52.0 | 3.75e-01 | 97.3% | 40.5% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.56 | 49.0 | 4.56e-01 | 92.9% | 78.5% |
| 3jrtA00 | 1.20.120.1060 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 47.0 | 4.11e-01 | 92.0% | 74.7% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.55 | 44.0 | 4.49e-01 | 87.5% | 86.6% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.55 | 42.0 | 4.05e-01 | 82.1% | 89.3% |
| 4bwcA02 | 1.10.439.20 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 | 0.53 | 35.0 | 3.52e-01 | 72.3% | 64.1% |
| 2o7tA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 43.0 | 3.68e-01 | 88.4% | 56.2% |
| 2cazE00 | 1.20.1440.200 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Vps28 N-terminal domain | 0.52 | 42.0 | 4.42e-01 | 95.5% | 98.0% |
| 6dewA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 46.0 | 3.90e-01 | 100.0% | 91.1% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.50 | 42.0 | 4.07e-01 | 92.0% | 96.1% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.50 | 43.0 | 4.28e-01 | 96.4% | 99.1% |
ECOD (74)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3405975 | 633.21.1.42 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF4781 | 0.84 | 76.0 | 6.28e-01 | 95.5% | 65.9% |
| 3213117 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.80 | 61.0 | 6.56e-01 | 91.1% | 93.7% |
| 4992790 | 601.2.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes | 0.79 | 44.0 | 4.82e-01 | 87.5% | 66.3% |
| 3784566 | 604.1.1.191 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF29057 | 0.76 | 62.0 | 6.56e-01 | 92.9% | 97.0% |
| 3256821 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.75 | 57.0 | 5.56e-01 | 92.9% | 73.3% |
| 3609374 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.75 | 61.0 | 6.20e-01 | 92.0% | 88.2% |
| 3960319 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.75 | 66.0 | 5.70e-01 | 95.5% | 77.6% |
| 3741603 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.74 | 63.0 | 6.11e-01 | 92.9% | 81.6% |
| 3687571 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.74 | 60.0 | 5.57e-01 | 92.9% | 69.3% |
| 3172910 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.74 | 57.0 | 5.94e-01 | 92.0% | 87.6% |
| 3497418 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.74 | 55.0 | 5.80e-01 | 92.9% | 87.0% |
| 5083776 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.72 | 53.0 | 5.72e-01 | 90.2% | 89.5% |
| 3787587 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.72 | 56.0 | 5.91e-01 | 92.0% | 92.0% |
| 3253938 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.72 | 50.0 | 4.96e-01 | 88.4% | 68.7% |
| 3477418 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.72 | 50.0 | 5.36e-01 | 75.9% | 83.2% |
| 3180405 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.72 | 63.0 | 4.10e-01 | 95.5% | 54.6% |
| 5084013 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.72 | 52.0 | 5.26e-01 | 91.1% | 76.4% |
| 4363138 | 192.29.1.125 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cytochrom_C_asm | 0.72 | 64.0 | 4.74e-01 | 96.4% | 59.6% |
| 3341807 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.71 | 52.0 | 5.25e-01 | 92.9% | 76.4% |
| 3276887 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.71 | 57.0 | 5.73e-01 | 92.9% | 83.5% |
| 4072081 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.71 | 62.0 | 5.01e-01 | 95.5% | 82.3% |
| 3061928 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 61.0 | 5.11e-01 | 92.9% | 66.1% |
| 3786282 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.71 | 56.0 | 5.50e-01 | 89.3% | 78.3% |
| 3427750 | 633.21.1.18 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom | 0.71 | 62.0 | 5.51e-01 | 96.4% | 75.6% |
| 3518320 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 57.0 | 5.80e-01 | 92.9% | 89.1% |
| 3724303 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 56.0 | 5.15e-01 | 93.8% | 65.5% |
| 3425147 | 109.4.1.1557 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_RNF123 | 0.70 | 60.0 | 4.98e-01 | 95.5% | 53.3% |
| 3195933 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.70 | 59.0 | 4.76e-01 | 92.0% | 54.9% |
| 3845582 | 109.40.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › Ctf4_C | 0.70 | 48.0 | 4.59e-01 | 94.6% | 60.8% |
| 3828970 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.70 | 50.0 | 5.37e-01 | 92.0% | 87.4% |
| 5041952 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.69 | 59.0 | 5.62e-01 | 94.6% | 83.0% |
| 3725615 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.69 | 45.0 | 5.26e-01 | 92.9% | 93.8% |
| 3616967 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.69 | 60.0 | 4.60e-01 | 95.5% | 69.0% |
| 3269731 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.69 | 59.0 | 5.87e-01 | 94.6% | 98.3% |
| 3594516 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.68 | 56.0 | 4.75e-01 | 89.3% | 54.1% |
| 5067623 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 56.0 | 5.67e-01 | 89.3% | 92.7% |
| 3441715 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.68 | 55.0 | 5.60e-01 | 93.8% | 89.1% |
| 3713159 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.68 | 56.0 | 5.54e-01 | 92.0% | 84.2% |
| 3873872 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.68 | 60.0 | 5.20e-01 | 96.4% | 72.4% |
| 3197870 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 58.0 | 5.47e-01 | 92.9% | 80.0% |
| 3296811 | 109.24.1.9 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › PF25999 | 0.68 | 60.0 | 4.97e-01 | 96.4% | 57.5% |
| 3678146 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.68 | 50.0 | 4.72e-01 | 92.0% | 62.9% |
| 3879381 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.67 | 58.0 | 5.21e-01 | 95.5% | 83.2% |
| 3737845 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.67 | 57.0 | 3.65e-01 | 93.8% | 46.4% |
| 4012748 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.66 | 56.0 | 4.08e-01 | 92.0% | 48.1% |
| 3279022 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.66 | 57.0 | 4.31e-01 | 95.5% | 71.5% |
| 3240455 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 48.0 | 5.26e-01 | 90.2% | 96.7% |
| 5009683 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 55.0 | 5.06e-01 | 94.6% | 71.4% |
| 3603171 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.65 | 55.0 | 4.77e-01 | 92.0% | 68.0% |
| 3746251 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.65 | 56.0 | 5.03e-01 | 96.4% | 74.4% |
| 3273401 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.65 | 56.0 | 4.59e-01 | 94.6% | 84.4% |
| 3197267 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 53.0 | 3.45e-01 | 95.5% | 19.8% |
| 3766400 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.64 | 55.0 | 5.62e-01 | 95.5% | 98.2% |
| 3905839 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.64 | 53.0 | 4.56e-01 | 92.0% | 94.1% |
| 4091932 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 54.0 | 5.07e-01 | 92.0% | 92.6% |
| 3398541 | 109.4.1.1492 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_SCC3-SA, PF31007 | 0.63 | 55.0 | 3.70e-01 | 97.3% | 43.2% |
| 3940779 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 52.0 | 5.37e-01 | 88.4% | 94.3% |
| 3494871 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 55.0 | 3.46e-01 | 97.3% | 27.6% |
| 3701245 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.62 | 54.0 | 5.50e-01 | 94.6% | 100.0% |
| 3730372 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.61 | 50.0 | 4.20e-01 | 90.2% | 50.8% |
| 1291132 | 109.40.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › Ctf4_C | 0.61 | 50.0 | 4.77e-01 | 98.2% | 75.4% |
| 4000290 | 192.29.1.188 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › F_actin_bind | 0.60 | 48.0 | 4.63e-01 | 89.3% | 74.6% |
| 3940244 | 5001.1.1.35 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srsx | 0.60 | 50.0 | 3.72e-01 | 93.8% | 77.4% |
| 3922393 | 601.39.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Enhancer of filamentation 1 › Enhancer of filamentation 1 | 0.59 | 46.0 | 4.29e-01 | 93.8% | 66.7% |
| 4032308 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.59 | 51.0 | 4.46e-01 | 95.5% | 69.4% |
| 3617789 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 48.0 | 3.87e-01 | 86.6% | 51.0% |
| 5048496 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 48.0 | 4.00e-01 | 91.1% | 80.5% |
| 5078219 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.57 | 50.0 | 4.24e-01 | 94.6% | 59.4% |
| 4009028 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.54 | 43.0 | 4.22e-01 | 94.6% | 79.2% |
| 3963163 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.54 | 44.0 | 4.00e-01 | 90.2% | 70.3% |
| 3709302 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.53 | 43.0 | 4.17e-01 | 99.1% | 77.6% |
| 4289864 | 601.25.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain | 0.50 | 43.0 | 3.94e-01 | 95.5% | 74.7% |
| 3648924 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 36.0 | 3.92e-01 | 94.6% | 89.5% |
| 3611706 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.50 | 39.0 | 3.73e-01 | 82.1% | 76.2% |
D2
medium
residues 113-197
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.66 | 39.0 | 3.48e-01 | 75.3% | 40.0% |
| 3lphC00 | 6.10.140.630 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 35.0 | 4.09e-01 | 77.6% | 75.9% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.63 | 40.0 | 4.09e-01 | 81.2% | 64.7% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.63 | 47.0 | 3.62e-01 | 78.8% | 72.8% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.62 | 40.0 | 4.22e-01 | 77.6% | 73.3% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 55.0 | 4.45e-01 | 97.6% | 74.1% |
| 3vbbE01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.62 | 45.0 | 3.99e-01 | 76.5% | 57.1% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.61 | 43.0 | 3.70e-01 | 76.5% | 81.5% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.60 | 43.0 | 4.38e-01 | 78.8% | 76.8% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 51.0 | 4.22e-01 | 96.5% | 76.1% |
| 1siqA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 51.0 | 4.19e-01 | 96.5% | 73.5% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 50.0 | 4.12e-01 | 97.6% | 75.0% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 49.0 | 3.67e-01 | 96.5% | 63.6% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.57 | 44.0 | 3.85e-01 | 84.7% | 68.7% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 47.0 | 3.40e-01 | 97.6% | 67.5% |
| 3e9lA02 | 1.20.80.40 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region | 0.55 | 38.0 | 3.67e-01 | 91.8% | 63.2% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 41.0 | 3.67e-01 | 80.0% | 57.5% |
| 3lomA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 46.0 | 3.27e-01 | 100.0% | 61.1% |
| 6cgaC02 | 1.20.58.860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 40.0 | 4.17e-01 | 80.0% | 85.9% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 40.0 | 3.81e-01 | 83.5% | 71.8% |
| 7wz5A01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 40.0 | 3.33e-01 | 83.5% | 95.4% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.52 | 45.0 | 3.49e-01 | 97.6% | 65.4% |
| 6mgiA03 | 1.20.1440.90 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Phosphoenolpyruvate/pyruvate domain | 0.51 | 45.0 | 3.83e-01 | 96.5% | 65.0% |
| 3bhgA01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.51 | 36.0 | 3.29e-01 | 80.0% | 53.9% |
| 3ucaA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.50 | 43.0 | 3.04e-01 | 96.5% | 32.8% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4639996 | 150.7.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PE › PE › PE | 0.73 | 41.0 | 4.05e-01 | 78.8% | 52.2% |
| 5075878 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.71 | 44.0 | 4.61e-01 | 97.6% | 67.5% |
| 3684835 | 3712.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 | 0.68 | 46.0 | 4.44e-01 | 75.3% | 62.1% |
| 3620375 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 46.0 | 3.73e-01 | 76.5% | 40.0% |
| 3455464 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.65 | 45.0 | 3.73e-01 | 88.2% | 40.0% |
| 4553515 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.65 | 37.0 | 3.76e-01 | 72.9% | 57.6% |
| 3391384 | 5030.1.1.0 ↗ | extended segments › Photosystem II reaction center protein L, PsbL › Photosystem II reaction center protein L, PsbL › Photosystem II reaction center protein L, PsbL | 0.64 | 46.0 | 4.66e-01 | 78.8% | 75.3% |
| 3397013 | 148.1.3.60 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › DUF4818 | 0.63 | 47.0 | 3.98e-01 | 78.8% | 73.8% |
| 3971097 | 3562.1.1.8 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › IspA | 0.62 | 51.0 | 4.88e-01 | 95.3% | 76.0% |
| 2555592 | 5069.1.1.3 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_I | 0.62 | 38.0 | 3.90e-01 | 78.8% | 62.4% |
| 3605561 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 49.0 | 3.97e-01 | 94.1% | 45.5% |
| 3644022 | 6055.1.1.3 ↗ | extended segments › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC › Utp11 | 0.60 | 41.0 | 3.86e-01 | 71.8% | 57.1% |
| 5012473 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.60 | 45.0 | 4.09e-01 | 78.8% | 60.0% |
| 3625463 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.60 | 45.0 | 3.84e-01 | 80.0% | 80.0% |
| 4031283 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.60 | 44.0 | 3.57e-01 | 75.3% | 84.7% |
| 4020856 | 650.1.1.0 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain | 0.60 | 49.0 | 4.22e-01 | 89.4% | 63.0% |
| 3584894 | 605.1.1.238 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › CNNM | 0.60 | 45.0 | 4.44e-01 | 80.0% | 78.9% |
| 3954313 | 150.5.1.52 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PE | 0.59 | 44.0 | 4.29e-01 | 78.8% | 73.7% |
| 3906191 | 4323.1.1.1 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.58 | 43.0 | 3.45e-01 | 76.5% | 43.9% |
| 2673302 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.58 | 47.0 | 4.39e-01 | 100.0% | 70.8% |
| 3375405 | 4323.1.1.1 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.58 | 47.0 | 3.90e-01 | 88.2% | 52.7% |
| 3968997 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.58 | 43.0 | 3.72e-01 | 78.8% | 65.4% |
| 3808845 | 5086.1.1.90 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › V_ATPase_I | 0.57 | 47.0 | 3.88e-01 | 88.2% | 52.7% |
| 3990854 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.57 | 41.0 | 4.01e-01 | 72.9% | 73.3% |
| 3840552 | 5086.1.1.90 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › V_ATPase_I | 0.57 | 46.0 | 3.73e-01 | 87.1% | 51.5% |
| 3634169 | 4177.1.1.27 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_4 | 0.57 | 46.0 | 3.26e-01 | 89.4% | 62.9% |
| 3331533 | 3559.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 | 0.56 | 41.0 | 3.39e-01 | 75.3% | 46.9% |
| 3781132 | 3755.4.1.48 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › V_ATPase_I | 0.56 | 47.0 | 3.89e-01 | 90.6% | 62.7% |
| 4084556 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.55 | 41.0 | 3.68e-01 | 78.8% | 60.0% |
| 4000050 | 5069.1.3.84 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › 7TM_GPCR_Srsx | 0.55 | 45.0 | 3.95e-01 | 91.8% | 65.4% |
| 4444553 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.53 | 42.0 | 2.78e-01 | 83.5% | 22.8% |
| 3254210 | 192.4.1.2 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › MRP-L47 | 0.53 | 45.0 | 3.94e-01 | 92.9% | 67.7% |
| 4956171 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.52 | 43.0 | 4.20e-01 | 95.3% | 81.1% |
| 3979628 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 44.0 | 3.69e-01 | 98.8% | 60.0% |