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gene_114212

Arc-Vir

IMGVR_UViG_7000000193_000088-7000000193-SRS048870_WUGC_scaffold_52489__gene_114212

Identity

Protein ID:
gene_114212 ↗
Kingdom:
archaea

Quality

91.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 127-158
PDB
Domain cluster: representative
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4k3cA01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.71 54.0 4.29e-01 100.0% 73.2%
1mhxA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.69 48.0 3.92e-01 81.2% 36.9%
2qkdA01 2.20.25.420 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › ZPR1, zinc finger domain 0.68 50.0 4.47e-01 87.5% 56.2%
2qlvB02 2.20.25.290 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.66 46.0 4.47e-01 87.5% 63.2%
3hm2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.66 51.0 3.35e-01 100.0% 23.4%
1d6uA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.65 52.0 2.96e-01 100.0% 29.5%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 45.0 3.18e-01 75.0% 57.9%
1cx8A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.64 48.0 2.87e-01 100.0% 12.4%
1l3iA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 52.0 3.32e-01 100.0% 37.3%
5da9A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 45.0 2.63e-01 81.2% 7.2%
7b1cD01 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.63 45.0 3.45e-01 81.2% 29.5%
1ya5T01 2.20.160.10 Mainly Beta › Single Sheet › titin filament fold › titin domain like 0.63 43.0 3.42e-01 78.1% 29.8%
2xzmJ00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.62 46.0 3.49e-01 100.0% 50.5%
6j09A04 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.62 46.0 3.81e-01 100.0% 45.5%
1fneA01 3.10.320.10 Alpha Beta › Roll › Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 › Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 0.62 42.0 3.39e-01 78.1% 31.6%
2bs2B01 3.10.20.30 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain 0.61 44.0 3.23e-01 81.2% 26.4%
6tmfM00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.61 47.0 3.52e-01 100.0% 54.9%
5mu3B00 3.40.50.12050 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 43.0 2.81e-01 78.1% 15.3%
3ulpD00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 44.0 3.22e-01 87.5% 32.7%
1kfiA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.60 42.0 2.89e-01 78.1% 19.2%
3ks7A02 2.60.120.230 Mainly Beta › Sandwich › Jelly Rolls › 0.60 44.0 2.96e-01 100.0% 81.6%
1rm6A03 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.60 47.0 3.31e-01 96.9% 25.0%
2znhA03 6.20.40.10 Special › Other non-globular › Porin MspA ribbon fold › 0.60 45.0 4.28e-01 100.0% 87.2%
8afoA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 45.0 3.53e-01 100.0% 61.4%
4mh4A02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.59 44.0 3.47e-01 100.0% 42.6%
5cm2Z00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 42.0 2.70e-01 75.0% 39.1%
4mx8C01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.58 41.0 2.59e-01 75.0% 14.8%
1zoyB01 3.10.20.30 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain 0.58 42.0 3.02e-01 78.1% 25.5%
6pfzD02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.57 43.0 2.66e-01 100.0% 42.8%
1bdfA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.57 44.0 3.25e-01 100.0% 33.0%
7s7rA01 2.60.40.2860 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 39.0 2.78e-01 87.5% 62.1%
2z13A00 2.30.29.170 Mainly Beta › Roll › PH-domain like › 0.56 40.0 2.86e-01 78.1% 23.1%
4f0aB02 3.30.2460.20 Alpha Beta › 2-Layer Sandwich › Endo-n-acetylneuraminidase fold › Wnt (Wingless and Int-1), C-terminal domain 0.56 42.0 3.62e-01 100.0% 72.1%
2k6vA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.55 38.0 2.51e-01 71.9% 65.1%
1k8kA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.54 38.0 2.97e-01 81.2% 33.7%
4ozjA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 40.0 2.92e-01 87.5% 81.7%
1fl7D00 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.54 38.0 2.85e-01 78.1% 23.6%
1wnhA01 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 42.0 3.11e-01 100.0% 36.0%
5xyiU00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.53 38.0 2.94e-01 90.6% 54.6%
3m1cA01 3.10.360.40 Alpha Beta › Roll › Antimicrobial Peptide, Beta-defensin 2; Chain A › 0.53 41.0 3.73e-01 100.0% 78.8%
3j7aV00 2.40.50.1000 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.53 38.0 2.70e-01 90.6% 21.9%
3k8aB00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 36.0 2.84e-01 87.5% 35.9%
4cbgD02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 36.0 2.59e-01 100.0% 40.4%
7w3rB01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.52 36.0 2.12e-01 78.1% 76.5%
1j2vA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 38.0 2.97e-01 100.0% 36.6%
7o4xA01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 38.0 2.99e-01 100.0% 35.4%
3g3sA01 3.40.630.110 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › GNAT acetyltransferase-like 0.51 35.0 2.72e-01 100.0% 26.7%
5aj3Q00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.51 38.0 2.88e-01 90.6% 29.4%
2b9dA01 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.51 35.0 3.45e-01 75.0% 61.5%
3g2eB00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.51 38.0 2.52e-01 100.0% 17.8%
4kt5C00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 39.0 3.07e-01 100.0% 76.1%
ECOD (55)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3240891 7.1.1.0 ↗ beta barrels › PDZ domain › PDZ domain › PDZ domain 0.76 53.0 3.83e-01 78.1% 25.0%
4248693 5084.1.1.0 ↗ beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like 0.75 54.0 3.35e-01 78.1% 13.5%
3701672 2004.1.1.26 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin 0.73 52.0 3.32e-01 81.2% 15.3%
3519176 4154.1.1.2 ↗ beta duplicates or obligate multimers › E2F-DP heterodimerization region › E2F-DP heterodimerization region › E2F-DP heterodimerization region › E2F_CC-MB 0.72 55.0 3.93e-01 100.0% 27.6%
3330537 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.71 52.0 3.29e-01 84.4% 16.2%
3716046 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.71 54.0 2.97e-01 90.6% 31.5%
5022396 3459.1.1.0 ↗ beta sandwiches › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule 0.70 50.0 3.82e-01 78.1% 31.2%
3264140 3082.1.1.0 ↗ extended segments › C-terminal region of nonsense mediated decay factor UPF2 › C-terminal region of nonsense mediated decay factor UPF2 › C-terminal region of nonsense mediated decay factor UPF2 0.70 48.0 4.78e-01 81.2% 68.6%
3672794 207.1.1.67 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1,LRRNT_2,LRR_4,LRR_6 0.68 53.0 2.97e-01 100.0% 20.4%
4899007 3121.1.1.0 ↗ a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.66 50.0 4.18e-01 100.0% 48.6%
3476505 328.1.1.1 ↗ a+b two layers › IF3-like › AlbA-like › AlbA-like › Alba 0.66 51.0 3.60e-01 100.0% 42.3%
None — 0.65 54.0 3.23e-01 100.0% 89.3%
3558274 4096.1.1.1 ↗ a+b two layers › NAP-like › NAP-like › NAP-like › NAP 0.64 46.0 2.76e-01 96.9% 10.0%
3425274 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.64 48.0 3.24e-01 96.9% 21.9%
4159896 2003.1.1.59 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_5 0.63 45.0 2.59e-01 87.5% 9.7%
5074082 11.1.1.9 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_N 0.63 46.0 3.08e-01 84.4% 22.8%
3483369 2498.1.1.0 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.63 49.0 2.95e-01 96.9% 30.6%
3429988 387.1.1.0 ↗ few secondary structure elements › omega toxin-like › omega toxin-related › omega toxin-related 0.63 44.0 4.48e-01 75.0% 96.0%
3719891 2.1.1.28 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › mRNA_cap_C 0.63 47.0 3.42e-01 90.6% 28.7%
4119784 230.1.1.5 ↗ a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.63 44.0 3.07e-01 78.1% 29.8%
1245468 391.1.1.1 ↗ few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module › fn1 0.62 44.0 4.20e-01 78.1% 59.5%
1125236 4186.1.1.1 ↗ beta barrels › Ribosomal protein L21p › Ribosomal protein L21p › Ribosomal protein L21p › Ribosomal_L21p 0.62 44.0 3.20e-01 81.2% 23.9%
3058947 221.1.1.8 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PI3K_rbd 0.62 44.0 3.12e-01 81.2% 21.8%
3931635 327.11.2.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.61 45.0 3.77e-01 100.0% 44.0%
3380640 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 47.0 2.88e-01 100.0% 31.6%
1153578 75.1.1.1 ↗ beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase 0.61 42.0 3.42e-01 78.1% 35.7%
4141218 4099.1.1.6 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Ctf19_RWD2 0.60 44.0 3.44e-01 81.2% 32.5%
3675789 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 45.0 3.70e-01 87.5% 82.9%
5032176 1.1.3.2 ↗ beta barrels › cradle loop barrel › RIFT-related › AbrB › MazE_antitoxin 0.60 46.0 4.00e-01 100.0% 50.0%
3601335 298.1.1.0 ↗ a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 0.59 46.0 2.90e-01 90.6% 47.2%
4860339 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 41.0 3.17e-01 81.2% 27.0%
5007619 3010.1.1.2 ↗ a/b three-layered sandwiches › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains › Lon_C 0.58 41.0 3.05e-01 84.4% 26.4%
5078891 1.1.3.2 ↗ beta barrels › cradle loop barrel › RIFT-related › AbrB › MazE_antitoxin 0.58 46.0 4.00e-01 100.0% 54.5%
3734626 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.58 40.0 2.51e-01 78.1% 11.4%
4022589 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.58 40.0 2.49e-01 78.1% 11.1%
3292891 2003.1.5.121 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DUF1442 0.57 41.0 2.65e-01 93.8% 16.2%
3593251 7516.1.1.0 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases 0.57 43.0 2.50e-01 100.0% 57.0%
3666034 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.57 44.0 3.24e-01 100.0% 30.0%
3486912 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.57 41.0 2.51e-01 87.5% 19.6%
3605352 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 47.0 3.20e-01 96.9% 30.0%
3610634 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.56 45.0 2.60e-01 100.0% 12.7%
4022336 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.56 39.0 2.33e-01 100.0% 20.3%
3593809 304.31.1.0 ↗ a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase 0.56 42.0 3.16e-01 100.0% 60.0%
4054285 5.1.4.139 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40_2 0.56 40.0 2.30e-01 100.0% 17.8%
3969378 3121.1.1.0 ↗ a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.56 44.0 3.64e-01 100.0% 78.6%
3707076 511.1.1.0 ↗ beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.55 40.0 2.78e-01 100.0% 20.3%
2772633 71.1.1.15 ↗ beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › UCP033729 0.55 40.0 2.67e-01 84.4% 15.9%
3968270 3103.1.1.2 ↗ alpha arrays › Uncharacterized protein yqbN › Uncharacterized protein yqbN › Uncharacterized protein yqbN › Phage_TAC_13 0.54 37.0 2.78e-01 78.1% 26.4%
3503534 5057.1.1.1 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.54 42.0 2.85e-01 93.8% 24.1%
4197190 812.1.1.1 ↗ a+b duplicates or obligate multimers › MinE-like › Cell division protein MinE topological specificity domain › Cell division protein MinE topological specificity domain › MinE 0.53 40.0 3.52e-01 100.0% 63.3%
3819930 3364.1.1.2 ↗ few secondary structure elements › Epidermal patterning factor-like protein 9 › Epidermal patterning factor-like protein 9 › Epidermal patterning factor-like protein 9 › EPF 0.53 37.0 3.66e-01 90.6% 82.5%
4089814 327.13.1.2 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system › YscJ_FliF_C 0.52 36.0 2.59e-01 100.0% 57.6%
4321860 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.51 38.0 2.51e-01 100.0% 33.2%
5009974 2487.1.1.9 ↗ a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" › Cyclase 0.51 39.0 2.83e-01 96.9% 28.7%
1822815 6173.1.1.1 ↗ beta barrels › V1/V2 domain in HIV gp120 › V1/V2 domain in HIV gp120 › V1/V2 domain in HIV gp120 › GP120 0.51 38.0 3.59e-01 100.0% 68.8%