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Ig7659_scaffold_8_prodigal-single.1__X__X__00029
Bact-VirIg7659_scaffold_8_prodigal-single.1__X__X__00029
Identity
- Kingdom:
- phage
Quality
70.4
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 49-185
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.72 | 36.0 | 3.93e-01 | 94.9% | 58.0% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 36.0 | 4.18e-01 | 95.6% | 68.9% |
| 3terA00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 36.0 | 3.92e-01 | 94.2% | 63.0% |
| 3o3mB01 | 1.20.1270.370 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 29.0 | 3.35e-01 | 73.7% | 56.3% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 34.0 | 4.09e-01 | 94.9% | 80.2% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 32.0 | 4.13e-01 | 94.2% | 96.1% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.55 | 41.0 | 3.77e-01 | 79.6% | 90.2% |
| 4ke2A00 | 6.10.140.1860 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 36.0 | 3.25e-01 | 94.2% | 47.4% |
| 1kz7A01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.54 | 37.0 | 3.36e-01 | 71.5% | 92.2% |
| 4d8mA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.53 | 38.0 | 3.30e-01 | 73.0% | 78.2% |
| 1b8dA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.53 | 37.0 | 3.55e-01 | 81.0% | 59.1% |
| 4mycA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.52 | 47.0 | 3.51e-01 | 97.1% | 71.0% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3927845 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 40.0 | 4.10e-01 | 71.5% | 67.7% |
| 3207391 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.60 | 39.0 | 3.91e-01 | 75.2% | 62.8% |
| 3237985 | 150.1.1.24 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Prominin | 0.59 | 43.0 | 3.50e-01 | 75.9% | 62.4% |
| 3779631 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.59 | 41.0 | 3.60e-01 | 71.5% | 70.0% |
| 3467833 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 41.0 | 3.46e-01 | 72.3% | 74.1% |
| 3978264 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.57 | 43.0 | 4.18e-01 | 78.1% | 81.3% |
| 3404404 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.52 | 37.0 | 3.18e-01 | 71.5% | 96.7% |
| 4011121 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.52 | 38.0 | 2.88e-01 | 75.2% | 67.5% |
| 3484968 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.52 | 40.0 | 3.40e-01 | 81.0% | 68.7% |
| 3477279 | 5057.1.1.18 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Otopetrin | 0.51 | 40.0 | 3.29e-01 | 82.5% | 88.2% |
D2
medium
residues 198-271_404-433
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5bw0F00 | 3.30.1300.30 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like | 0.51 | 34.0 | 3.66e-01 | 78.8% | 78.0% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3764448 | 887.1.1.4 ↗ | a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30_N | 0.61 | 46.0 | 3.57e-01 | 77.9% | 68.6% |
| 3957539 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.59 | 36.0 | 3.37e-01 | 71.2% | 49.6% |
| 3960071 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.58 | 35.0 | 2.80e-01 | 71.2% | 29.7% |
| 4249123 | 2011.1.1.8 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 | 0.56 | 46.0 | 3.53e-01 | 90.4% | 76.3% |
| 4034310 | 2008.1.1.107 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD | 0.54 | 44.0 | 3.57e-01 | 88.5% | 85.9% |
| 4458171 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.54 | 38.0 | 3.50e-01 | 72.1% | 93.8% |
| 3506312 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.53 | 36.0 | 3.32e-01 | 71.2% | 100.0% |
| 4944167 | 4025.1.1.2 ↗ | alpha complex topology › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › NiFeSe_Hases | 0.52 | 47.0 | 3.44e-01 | 100.0% | 95.8% |
| 3990696 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.52 | 38.0 | 3.09e-01 | 77.9% | 40.5% |
| 3223761 | 320.2.1.0 ↗ | a+b two layers › R3H domain-like › Ribosomal protein S8, N-terminal domain › Ribosomal protein S8, N-terminal domain | 0.51 | 35.0 | 3.73e-01 | 80.8% | 77.7% |
| 3665695 | 2498.1.1.6 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 | 0.51 | 36.0 | 2.41e-01 | 100.0% | 16.6% |
| 3353072 | 4154.1.1.1 ↗ | beta duplicates or obligate multimers › E2F-DP heterodimerization region › E2F-DP heterodimerization region › E2F-DP heterodimerization region › DP | 0.50 | 40.0 | 3.94e-01 | 97.1% | 77.4% |
D3
medium
residues 272-403
Domain cluster:
representative
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.72 | 38.0 | 5.02e-01 | 79.5% | 93.2% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.71 | 57.0 | 4.64e-01 | 84.8% | 81.4% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.71 | 37.0 | 5.01e-01 | 81.1% | 98.5% |
| 5dn6J00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.69 | 38.0 | 4.87e-01 | 83.3% | 94.6% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.69 | 39.0 | 5.02e-01 | 84.8% | 98.6% |
| 7dluA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 37.0 | 4.12e-01 | 79.5% | 65.7% |
| 6qumQ00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.67 | 38.0 | 4.87e-01 | 83.3% | 98.6% |
| 2mpnA00 | 6.10.140.1340 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 34.0 | 4.53e-01 | 81.8% | 98.5% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.64 | 30.0 | 4.15e-01 | 82.6% | 90.6% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.64 | 39.0 | 4.75e-01 | 81.8% | 94.1% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.63 | 30.0 | 3.73e-01 | 82.6% | 71.6% |
| 2oauA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 33.0 | 3.68e-01 | 77.3% | 64.7% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 32.0 | 3.58e-01 | 87.9% | 63.8% |
| 2kg7B00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.61 | 37.0 | 4.27e-01 | 90.2% | 83.5% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 40.0 | 4.37e-01 | 81.1% | 82.6% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.59 | 31.0 | 3.49e-01 | 82.6% | 63.8% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.59 | 29.0 | 3.46e-01 | 77.3% | 69.0% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.59 | 33.0 | 3.26e-01 | 87.1% | 50.0% |
| 3ibpA01 | 1.20.58.850 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 30.0 | 3.86e-01 | 87.9% | 88.9% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.58 | 30.0 | 4.03e-01 | 82.6% | 95.6% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 23.0 | 2.94e-01 | 76.5% | 58.7% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.57 | 28.0 | 3.91e-01 | 74.2% | 98.4% |
| 4k7rA01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.56 | 49.0 | 3.67e-01 | 97.7% | 93.2% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 29.0 | 3.29e-01 | 86.4% | 62.7% |
| 2guzB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.56 | 27.0 | 3.69e-01 | 89.4% | 93.8% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.55 | 35.0 | 4.12e-01 | 86.4% | 91.5% |
| 1b06A01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.55 | 28.0 | 3.76e-01 | 82.6% | 95.5% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.55 | 37.0 | 3.46e-01 | 87.1% | 56.5% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.54 | 32.0 | 3.41e-01 | 97.7% | 64.7% |
| 1rfyB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.54 | 30.0 | 3.59e-01 | 88.6% | 79.5% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 32.0 | 3.31e-01 | 84.8% | 62.6% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 31.0 | 3.43e-01 | 97.7% | 72.1% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 39.0 | 3.11e-01 | 79.5% | 37.8% |
| 3ukmA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 39.0 | 3.28e-01 | 79.5% | 84.9% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 40.0 | 3.19e-01 | 79.5% | 81.7% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.52 | 31.0 | 3.34e-01 | 83.3% | 68.2% |
| 3ieeA02 | 1.20.58.820 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 | 0.52 | 28.0 | 3.10e-01 | 94.7% | 64.1% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 39.0 | 3.58e-01 | 79.5% | 79.6% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 31.0 | 3.48e-01 | 80.3% | 74.5% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.51 | 38.0 | 3.43e-01 | 78.0% | 72.0% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.51 | 41.0 | 4.09e-01 | 87.1% | 85.0% |
| 2xl4A00 | 1.20.120.1420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain | 0.51 | 33.0 | 3.27e-01 | 87.1% | 59.2% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 35.0 | 3.35e-01 | 84.1% | 59.9% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3785340 | 7581.1.1.3 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › ketoacyl-synt,Ketoacyl-synt_C | 0.65 | 55.0 | 3.40e-01 | 90.2% | 89.2% |
| 3697477 | 7581.1.1.7 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Ketoacyl-synt_C | 0.65 | 50.0 | 3.69e-01 | 80.3% | 67.6% |
| 4652715 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.63 | 30.0 | 3.38e-01 | 78.0% | 56.2% |
| 3596737 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.60 | 41.0 | 4.20e-01 | 87.1% | 71.5% |
| 2732157 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.59 | 32.0 | 4.20e-01 | 81.1% | 97.1% |
| 4267024 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.59 | 32.0 | 3.99e-01 | 89.4% | 89.3% |
| 3409209 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.57 | 33.0 | 3.52e-01 | 84.1% | 62.5% |
| 3390728 | 601.19.1.47 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › DUF4745 | 0.57 | 42.0 | 4.32e-01 | 93.9% | 80.0% |
| 5070806 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.57 | 25.0 | 3.45e-01 | 94.7% | 83.1% |
| 4027540 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.56 | 43.0 | 4.03e-01 | 79.5% | 66.3% |
| 3297107 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.56 | 33.0 | 3.86e-01 | 81.8% | 82.1% |
| 3930934 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.55 | 42.0 | 3.32e-01 | 80.3% | 73.6% |
| 3866995 | 604.1.1.24 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF4456 | 0.55 | 44.0 | 3.79e-01 | 85.6% | 79.0% |
| 4946565 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 35.0 | 3.66e-01 | 89.4% | 70.6% |
| 3296880 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.53 | 43.0 | 3.66e-01 | 86.4% | 80.9% |
| 3741801 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.53 | 34.0 | 3.51e-01 | 86.4% | 67.2% |
| 3519661 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.53 | 33.0 | 3.54e-01 | 84.1% | 72.7% |
| 3988781 | 604.6.1.63 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF3169 | 0.52 | 34.0 | 3.45e-01 | 100.0% | 64.4% |
| 3841126 | 5038.2.1.0 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like | 0.52 | 37.0 | 3.36e-01 | 75.0% | 75.1% |
| 3599499 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.51 | 36.0 | 3.45e-01 | 87.9% | 62.7% |
| 3600611 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.51 | 25.0 | 2.83e-01 | 82.6% | 57.0% |
D4
medium
residues 467-551
D5
medium
residues 552-745
Domain cluster:
representative
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.70 | 26.0 | 3.22e-01 | 74.2% | 52.4% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.69 | 30.0 | 3.82e-01 | 73.2% | 67.3% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.68 | 28.0 | 4.38e-01 | 98.5% | 98.6% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.66 | 37.0 | 4.80e-01 | 78.4% | 100.0% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 32.0 | 3.93e-01 | 72.7% | 71.9% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.63 | 34.0 | 3.74e-01 | 73.2% | 63.2% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.60 | 44.0 | 4.26e-01 | 78.9% | 66.7% |
| 2q7rB00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.59 | 33.0 | 3.71e-01 | 73.2% | 68.7% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.59 | 28.0 | 3.83e-01 | 72.2% | 88.4% |
| 3ay5A01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.57 | 29.0 | 3.52e-01 | 75.8% | 70.7% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.57 | 28.0 | 3.63e-01 | 75.8% | 81.5% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.57 | 38.0 | 4.19e-01 | 100.0% | 83.7% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.56 | 33.0 | 4.22e-01 | 73.2% | 99.1% |
| 2jswA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.55 | 39.0 | 3.96e-01 | 85.1% | 71.4% |
| 1nktA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.55 | 40.0 | 4.15e-01 | 73.7% | 98.9% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 43.0 | 3.84e-01 | 81.4% | 82.7% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.55 | 32.0 | 4.02e-01 | 73.7% | 96.5% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 38.0 | 4.16e-01 | 85.1% | 86.7% |
| 2w31A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 31.0 | 3.51e-01 | 86.6% | 69.7% |
| 7zd5C01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.54 | 43.0 | 3.72e-01 | 83.5% | 84.2% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 38.0 | 4.33e-01 | 81.4% | 93.9% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.54 | 43.0 | 3.60e-01 | 83.5% | 77.8% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 42.0 | 4.17e-01 | 82.5% | 93.8% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.53 | 38.0 | 3.83e-01 | 85.1% | 71.5% |
| 1qvrC04 | 6.10.140.130 | Special › Helix non-globular › Helix Hairpins › | 0.53 | 27.0 | 3.41e-01 | 75.3% | 80.5% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 41.0 | 3.98e-01 | 82.5% | 93.6% |
| 3wmeA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.52 | 40.0 | 3.45e-01 | 79.4% | 85.6% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.52 | 33.0 | 3.57e-01 | 71.6% | 73.6% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.51 | 34.0 | 4.11e-01 | 80.9% | 100.0% |
| 7zdtD01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.51 | 40.0 | 3.42e-01 | 83.0% | 84.0% |
| 3vkgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.51 | 30.0 | 3.40e-01 | 70.1% | 76.2% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 40.0 | 3.70e-01 | 84.5% | 98.4% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5020665 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.67 | 41.0 | 3.64e-01 | 100.0% | 41.8% |
| 3741872 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.60 | 49.0 | 5.01e-01 | 85.1% | 98.9% |
| 3655748 | 601.1.2.118 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CASP_dom | 0.59 | 43.0 | 4.76e-01 | 95.4% | 96.6% |
| 3214864 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.58 | 41.0 | 4.58e-01 | 86.6% | 92.0% |
| 4020167 | 633.26.1.0 ↗ | alpha bundles › Bromodomain-like › SidC lipid-binding domain › SidC lipid-binding domain | 0.58 | 35.0 | 4.36e-01 | 78.9% | 96.7% |
| 4261817 | 5086.1.1.91 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PRM1 | 0.57 | 46.0 | 4.65e-01 | 86.6% | 85.1% |
| 3411108 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.56 | 35.0 | 4.18e-01 | 77.3% | 89.6% |
| 4028568 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.56 | 34.0 | 3.77e-01 | 82.0% | 74.8% |
| 3471803 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.55 | 30.0 | 3.56e-01 | 70.1% | 76.8% |
| 3666345 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.55 | 34.0 | 3.82e-01 | 78.9% | 77.3% |
| 3894393 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.55 | 37.0 | 4.12e-01 | 100.0% | 86.0% |
| 3751245 | 633.23.1.8 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › DUF4534 | 0.55 | 38.0 | 4.26e-01 | 82.0% | 90.7% |
| 3212207 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 34.0 | 4.00e-01 | 78.9% | 89.6% |
| 3600968 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 34.0 | 3.89e-01 | 80.4% | 84.0% |
| 3891868 | 5086.1.1.21 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › CARMIL_C | 0.54 | 40.0 | 4.04e-01 | 77.8% | 92.5% |
| 4213065 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.54 | 39.0 | 4.21e-01 | 82.0% | 89.4% |
| 3568113 | 174.1.1.14 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › NKAIN | 0.53 | 31.0 | 3.82e-01 | 75.8% | 92.5% |
| 4997872 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.52 | 30.0 | 3.76e-01 | 74.2% | 93.8% |
| 3918623 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.51 | 34.0 | 3.86e-01 | 76.3% | 88.3% |
| 3867410 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.51 | 39.0 | 4.25e-01 | 83.0% | 96.9% |
| 5072280 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.51 | 34.0 | 3.28e-01 | 100.0% | 59.1% |
| 3556701 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.51 | 34.0 | 3.79e-01 | 80.4% | 84.5% |
| 3389617 | 174.1.1.29 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 | 0.50 | 32.0 | 3.81e-01 | 75.3% | 93.8% |
| 4149055 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.50 | 38.0 | 3.78e-01 | 83.5% | 75.0% |
| 3217694 | 174.1.1.31 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7027 | 0.50 | 33.0 | 3.58e-01 | 78.9% | 78.8% |
| 4305711 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 39.0 | 3.68e-01 | 82.0% | 77.1% |