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Ig8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00086
Bact-VirIg8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00086
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-78
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 48.0 | 4.43e-01 | 100.0% | 52.4% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.69 | 45.0 | 4.91e-01 | 100.0% | 83.9% |
| 3dp7B01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.68 | 51.0 | 4.84e-01 | 79.5% | 76.3% |
| 3zdqA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.68 | 61.0 | 4.00e-01 | 100.0% | 52.9% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 54.0 | 5.19e-01 | 100.0% | 76.7% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 46.0 | 4.66e-01 | 100.0% | 70.9% |
| 4lunU00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.66 | 51.0 | 3.42e-01 | 100.0% | 20.9% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.66 | 45.0 | 4.55e-01 | 100.0% | 70.5% |
| 3lnnB03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.66 | 51.0 | 5.42e-01 | 100.0% | 97.0% |
| 1zkeA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 56.0 | 5.59e-01 | 100.0% | 93.8% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 41.0 | 4.22e-01 | 98.7% | 69.9% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.63 | 46.0 | 4.99e-01 | 98.7% | 95.3% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.63 | 39.0 | 4.03e-01 | 94.9% | 66.2% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 57.0 | 5.29e-01 | 98.7% | 80.2% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.61 | 40.0 | 3.97e-01 | 100.0% | 62.7% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.60 | 49.0 | 4.32e-01 | 100.0% | 60.5% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.60 | 47.0 | 5.05e-01 | 100.0% | 97.1% |
| 2qe7G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.58 | 48.0 | 4.50e-01 | 100.0% | 73.2% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.58 | 50.0 | 4.59e-01 | 100.0% | 74.5% |
| 3vbbE01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.57 | 47.0 | 4.16e-01 | 100.0% | 60.5% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.57 | 39.0 | 4.05e-01 | 98.7% | 75.7% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 51.0 | 3.58e-01 | 100.0% | 33.1% |
| 4i0xH00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.56 | 49.0 | 4.96e-01 | 100.0% | 100.0% |
| 4g6dB02 | 6.10.140.1800 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 50.0 | 5.00e-01 | 100.0% | 100.0% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.56 | 48.0 | 4.35e-01 | 100.0% | 71.0% |
| 2oexA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.55 | 48.0 | 4.01e-01 | 100.0% | 60.8% |
| 1vluA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.54 | 48.0 | 3.35e-01 | 98.7% | 86.1% |
| 3lyeA00 | 3.20.20.60 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains | 0.54 | 45.0 | 3.14e-01 | 97.4% | 75.4% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 47.0 | 3.71e-01 | 100.0% | 75.0% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.53 | 47.0 | 4.74e-01 | 100.0% | 100.0% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 44.0 | 4.02e-01 | 100.0% | 68.6% |
| 3fayA00 | 1.10.506.10 | Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 | 0.52 | 43.0 | 2.83e-01 | 93.6% | 33.2% |
| 2zdiC00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 46.0 | 3.75e-01 | 100.0% | 64.2% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4505595 | 605.6.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like | 0.68 | 47.0 | 4.35e-01 | 73.1% | 81.0% |
| 4120495 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.66 | 50.0 | 3.15e-01 | 100.0% | 15.4% |
| 3880637 | 3755.3.1.465 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A | 0.65 | 50.0 | 4.13e-01 | 100.0% | 46.4% |
| 3407923 | 192.24.1.1 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RPC3_helical | 0.65 | 57.0 | 5.27e-01 | 100.0% | 86.0% |
| 3408277 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.64 | 49.0 | 4.36e-01 | 100.0% | 56.5% |
| 3933048 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.64 | 50.0 | 4.60e-01 | 100.0% | 66.0% |
| 3725592 | 192.8.1.35 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF6594 | 0.63 | 55.0 | 5.29e-01 | 100.0% | 95.6% |
| 2698234 | 192.24.1.1 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RPC3_helical | 0.61 | 56.0 | 4.97e-01 | 98.7% | 78.7% |
| 3518551 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 51.0 | 3.34e-01 | 92.3% | 22.5% |
| 4988997 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.60 | 54.0 | 4.10e-01 | 100.0% | 44.4% |
| 3574610 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.59 | 51.0 | 3.85e-01 | 97.4% | 100.0% |
| 3229095 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.59 | 54.0 | 4.96e-01 | 100.0% | 96.0% |
| 3197615 | 3755.3.1.355 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Uds1 | 0.58 | 50.0 | 4.37e-01 | 100.0% | 76.8% |
| 5041482 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.57 | 53.0 | 4.93e-01 | 100.0% | 92.6% |
| 3592587 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.57 | 49.0 | 4.22e-01 | 94.9% | 98.4% |
| 4120406 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.57 | 51.0 | 4.58e-01 | 100.0% | 70.9% |
| 4932148 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.57 | 51.0 | 4.37e-01 | 100.0% | 63.2% |
| 4937169 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.56 | 51.0 | 4.53e-01 | 100.0% | 71.8% |
| 4429833 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.56 | 50.0 | 4.48e-01 | 100.0% | 70.9% |
| 3477447 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.56 | 50.0 | 4.36e-01 | 100.0% | 74.2% |
| 5025813 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.56 | 50.0 | 4.47e-01 | 100.0% | 71.8% |
| 3964486 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.56 | 49.0 | 3.93e-01 | 100.0% | 49.4% |
| 5056868 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.54 | 48.0 | 3.05e-01 | 100.0% | 21.3% |
| 1632108 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.54 | 48.0 | 4.55e-01 | 100.0% | 85.9% |
| 4951651 | 5042.1.1.1 ↗ | extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › CorA | 0.52 | 39.0 | 4.19e-01 | 100.0% | 91.2% |
| 4250162 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.51 | 44.0 | 3.75e-01 | 100.0% | 88.9% |
| 4070494 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.51 | 43.0 | 2.82e-01 | 100.0% | 19.4% |
| 3591633 | 1021.1.1.0 ↗ | a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases | 0.51 | 43.0 | 3.97e-01 | 100.0% | 70.9% |
| 3402327 | 3755.3.1.324 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 | 0.50 | 44.0 | 3.47e-01 | 100.0% | 47.1% |
D2
medium
residues 79-144
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.75 | 57.0 | 5.54e-01 | 83.3% | 78.7% |
| 6xm1A02 | 3.90.830.10 | Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a | 0.74 | 55.0 | 4.53e-01 | 78.8% | 57.5% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.72 | 53.0 | 5.07e-01 | 80.3% | 66.7% |
| 2btqB03 | 1.10.287.600 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.64 | 48.0 | 5.13e-01 | 83.3% | 100.0% |
| 3rlfF01 | 1.20.58.370 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › MalF N-terminal region-like | 0.64 | 43.0 | 4.01e-01 | 74.2% | 54.7% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1878710 | 4970.1.1.1 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.78 | 55.0 | 5.86e-01 | 83.3% | 87.5% |
| 3491310 | 3826.1.1.67 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Med10 | 0.75 | 55.0 | 5.27e-01 | 83.3% | 68.0% |
| 3787069 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.70 | 60.0 | 4.91e-01 | 100.0% | 54.3% |
| 2774421 | 616.1.1.1 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Ribosomal_S15 | 0.67 | 49.0 | 3.63e-01 | 78.8% | 34.6% |
| 3352228 | 2003.1.5.21 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS | 0.61 | 50.0 | 3.43e-01 | 97.0% | 24.5% |