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Ig8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00226
Bact-VirIg8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00226
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 117-239
Domain cluster:
rep: MT028491.1__QIG65861.1__phiOC_p196__00195__D164-290
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF23940.2 best | DUF7275 | 57.3 | 2.90e-15 | 95.1% | 59.0% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4qbuA02 | 3.40.366.10 | Alpha Beta › 3-Layer(aba) Sandwich › Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 › Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 | 0.63 | 43.0 | 3.48e-01 | 70.7% | 92.5% |
| 1t9kA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.55 | 41.0 | 3.99e-01 | 79.7% | 77.9% |
| 6jdbA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.52 | 42.0 | 3.98e-01 | 87.8% | 86.3% |
| 3hi0A03 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.52 | 46.0 | 3.98e-01 | 100.0% | 70.1% |
| 4by6D02 | 1.25.40.800 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 41.0 | 3.46e-01 | 87.0% | 62.2% |
| 7ed6A01 | 1.25.40.340 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain | 0.52 | 43.0 | 3.78e-01 | 92.7% | 99.5% |
| 2np5D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 38.0 | 3.54e-01 | 78.0% | 67.1% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3624000 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 46.0 | 3.76e-01 | 94.3% | 48.9% |
| 2988284 | 6110.1.1.0 ↗ | alpha superhelices › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain | 0.54 | 40.0 | 3.53e-01 | 77.2% | 80.2% |
| 5030306 | 186.1.1.4 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_4 | 0.53 | 34.0 | 3.81e-01 | 76.4% | 83.2% |
| 139559 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 38.0 | 3.93e-01 | 75.6% | 94.9% |
| 4108750 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.52 | 40.0 | 4.11e-01 | 82.1% | 91.7% |
| 4461553 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.51 | 40.0 | 3.92e-01 | 84.6% | 79.3% |
| 3434968 | 2007.2.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II | 0.50 | 44.0 | 3.72e-01 | 97.6% | 94.9% |
D2
medium
residues 1-55
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3er9B03 | 3.30.460.60 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Poxvirus poly(A) polymerase, nucleotidyltransferase domain | 0.68 | 58.0 | 4.47e-01 | 100.0% | 72.2% |
| 1cseI00 | 3.30.10.10 | Alpha Beta › 2-Layer Sandwich › Trypsin Inhibitor V; Chain A › Trypsin Inhibitor V, subunit A | 0.63 | 40.0 | 3.82e-01 | 80.0% | 55.6% |
| 5jo9A00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 43.0 | 2.92e-01 | 87.3% | 84.5% |
| 2proC01 | 3.30.300.50 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.56 | 36.0 | 3.43e-01 | 81.8% | 53.7% |
| 1hskA02 | 3.30.43.10 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 | 0.53 | 40.0 | 3.54e-01 | 85.5% | 86.4% |
| 4g1iA03 | 3.30.70.1770 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 41.0 | 3.89e-01 | 87.3% | 73.9% |
| 3hdcA01 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.52 | 41.0 | 3.27e-01 | 92.7% | 72.7% |
| 3v0aB02 | 1.20.1120.10 | Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" | 0.52 | 36.0 | 2.31e-01 | 76.4% | 71.3% |
| 2j6lA02 | 3.40.309.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 | 0.52 | 40.0 | 2.74e-01 | 83.6% | 23.8% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5080097 | 316.2.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like | 0.79 | 70.0 | 5.01e-01 | 100.0% | 42.5% |
| 4122066 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.78 | 69.0 | 5.00e-01 | 100.0% | 65.3% |
| 5075812 | 316.2.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like | 0.77 | 69.0 | 4.66e-01 | 100.0% | 37.9% |
| 4928558 | 316.2.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like | 0.76 | 68.0 | 4.83e-01 | 100.0% | 42.8% |
| 4993095 | 316.2.1.1 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like › AbiEi_1 | 0.75 | 66.0 | 4.46e-01 | 100.0% | 36.0% |
| 4992487 | 316.2.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like | 0.74 | 66.0 | 4.89e-01 | 100.0% | 47.1% |
| 4970292 | 316.2.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like | 0.74 | 65.0 | 4.59e-01 | 100.0% | 39.3% |
| 4984751 | 316.2.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like | 0.74 | 65.0 | 4.56e-01 | 100.0% | 38.9% |
| 3962010 | 101.1.2.863 ↗ | alpha arrays › HTH › HTH › winged helix domain › AbiEi_1 | 0.74 | 52.0 | 4.20e-01 | 80.0% | 38.2% |
| 5082556 | 316.2.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like | 0.73 | 64.0 | 4.34e-01 | 100.0% | 36.1% |
| 5079837 | 316.2.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like | 0.72 | 63.0 | 4.53e-01 | 100.0% | 38.7% |
| 5078154 | 316.2.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Rv2827c C-terminal domain-like › Rv2827c C-terminal domain-like | 0.71 | 62.0 | 4.62e-01 | 100.0% | 51.4% |
| 3570574 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.62 | 39.0 | 3.62e-01 | 85.5% | 48.6% |
| 4022567 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.61 | 53.0 | 4.06e-01 | 100.0% | 97.0% |
| 3515888 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.58 | 38.0 | 3.47e-01 | 85.5% | 49.3% |
| 3545685 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.57 | 39.0 | 2.47e-01 | 70.9% | 20.0% |
| 5022503 | 2004.1.3.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 0.57 | 41.0 | 3.10e-01 | 81.8% | 80.0% |
| 3902233 | 4.1.1.20 ↗ | beta barrels › SH3 › SH3 › SH3 › BAH | 0.56 | 41.0 | 3.13e-01 | 87.3% | 74.4% |
| 3956851 | 3785.1.1.0 ↗ | a+b three layers › Suppressor of Fused, C-terminal domain › Suppressor of Fused, C-terminal domain › Suppressor of Fused, C-terminal domain | 0.55 | 37.0 | 2.93e-01 | 87.3% | 33.0% |
| 3693077 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.55 | 40.0 | 2.82e-01 | 80.0% | 73.5% |
| 3279067 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.52 | 41.0 | 2.72e-01 | 100.0% | 88.4% |
| 5056808 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.51 | 45.0 | 2.96e-01 | 100.0% | 73.5% |
| 4947421 | 7516.1.1.10 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › CofC | 0.50 | 42.0 | 2.92e-01 | 100.0% | 69.0% |
D3
medium
residues 56-105
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF23940.2 best | DUF7275 | 28.2 | 2.40e-06 | 98.0% | 25.0% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4umwA04 | 3.40.1110.10 | Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N | 0.72 | 51.0 | 3.98e-01 | 100.0% | 33.6% |
| 3r4iA02 | 6.10.140.960 | Special › Helix non-globular › Helix Hairpins › | 0.69 | 47.0 | 4.51e-01 | 72.0% | 90.0% |
| 3zrhA01 | 1.25.40.560 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 47.0 | 3.95e-01 | 94.0% | 46.9% |
| 4dwnA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.60 | 40.0 | 3.34e-01 | 72.0% | 37.1% |
| 2h09A02 | 1.10.60.10 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Iron dependent repressor, metal binding and dimerisation domain | 0.55 | 41.0 | 3.96e-01 | 80.0% | 71.4% |
| 2px0A01 | 1.20.120.1380 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar FlhF biosynthesis protein, N domain | 0.55 | 39.0 | 3.58e-01 | 80.0% | 95.9% |
| 3fvvA02 | 1.20.1440.100 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › SG protein - dephosphorylation function | 0.54 | 41.0 | 3.64e-01 | 82.0% | 70.7% |
| 1uujA00 | 1.20.960.30 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.54 | 41.0 | 3.73e-01 | 90.0% | 59.2% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.52 | 35.0 | 3.08e-01 | 72.0% | 45.5% |
| 3b0xA01 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.51 | 39.0 | 3.40e-01 | 92.0% | 92.0% |
| 1g5bB00 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.50 | 41.0 | 2.80e-01 | 98.0% | 46.6% |
| 8himB01 | 3.90.1110.10 | Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2 | 0.50 | 40.0 | 3.07e-01 | 100.0% | 66.2% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5080934 | 316.1.1.18 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › AbiEii | 0.87 | 73.0 | 4.53e-01 | 96.0% | 18.2% |
| 3361550 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.72 | 57.0 | 4.17e-01 | 94.0% | 38.7% |
| 3939120 | 180.1.1.1 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 | 0.66 | 55.0 | 3.93e-01 | 100.0% | 48.8% |
| 4011385 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 47.0 | 3.47e-01 | 98.0% | 28.1% |
| 5022566 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.62 | 50.0 | 4.91e-01 | 92.0% | 89.1% |
| 3687150 | 109.4.1.348 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3517 | 0.62 | 43.0 | 2.79e-01 | 72.0% | 26.9% |
| 3605808 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.57 | 49.0 | 4.44e-01 | 100.0% | 78.6% |
| 5059586 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.56 | 39.0 | 3.42e-01 | 74.0% | 54.4% |
| 4957472 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.56 | 48.0 | 2.94e-01 | 100.0% | 24.6% |
| 5038931 | 7579.1.1.6 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 | 0.54 | 46.0 | 2.95e-01 | 98.0% | 46.0% |
| 5046448 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.53 | 37.0 | 3.57e-01 | 76.0% | 90.0% |
| 3519243 | 1074.1.1.0 ↗ | alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases | 0.52 | 38.0 | 2.64e-01 | 84.0% | 61.5% |
| 3927047 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.52 | 44.0 | 2.95e-01 | 96.0% | 27.5% |
| 4342279 | 103.1.1.6 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C | 0.51 | 45.0 | 4.20e-01 | 98.0% | 80.0% |