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Ig8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00465
Bact-VirIg8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00465
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 68-238
Domain cluster:
rep: AP018399.1__BBA65417.1__X__00269__D45-211
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3a11B01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.71 | 40.0 | 4.56e-01 | 70.2% | 72.8% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.68 | 39.0 | 4.48e-01 | 93.0% | 76.2% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 56.0 | 4.85e-01 | 91.8% | 89.4% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.65 | 33.0 | 4.01e-01 | 90.6% | 73.6% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 39.0 | 4.47e-01 | 92.4% | 80.6% |
| 7q37A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 55.0 | 5.08e-01 | 92.4% | 99.5% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 35.0 | 3.81e-01 | 88.9% | 63.4% |
| 4nooB00 | 1.10.8.1160 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.62 | 33.0 | 4.21e-01 | 92.4% | 89.5% |
| 1xioA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 52.0 | 4.82e-01 | 92.4% | 98.6% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 46.0 | 4.74e-01 | 80.7% | 94.4% |
| 8h6qD01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.59 | 46.0 | 3.84e-01 | 82.5% | 47.2% |
| 2a0uB01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.59 | 45.0 | 4.68e-01 | 86.0% | 85.6% |
| 1tj7A02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.58 | 52.0 | 4.47e-01 | 98.8% | 91.0% |
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 50.0 | 4.62e-01 | 95.3% | 98.7% |
| 5eroA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.57 | 46.0 | 3.78e-01 | 86.0% | 47.5% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 41.0 | 3.84e-01 | 73.7% | 60.0% |
| 3ddeB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.57 | 49.0 | 4.50e-01 | 94.7% | 98.7% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 40.0 | 3.75e-01 | 70.8% | 100.0% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 47.0 | 3.96e-01 | 88.9% | 92.3% |
| 6k41R00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 45.0 | 4.06e-01 | 88.9% | 94.2% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 44.0 | 3.80e-01 | 88.9% | 94.8% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.53 | 40.0 | 3.34e-01 | 78.4% | 87.5% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 38.0 | 3.59e-01 | 74.9% | 97.6% |
| 1m57A00 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.52 | 45.0 | 3.21e-01 | 95.9% | 79.9% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.51 | 37.0 | 3.10e-01 | 74.9% | 100.0% |
| 1vi0A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 35.0 | 3.72e-01 | 78.9% | 80.7% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 36.0 | 3.52e-01 | 73.1% | 90.6% |
| 4dvyP01 | 1.10.357.130 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.50 | 39.0 | 3.73e-01 | 80.1% | 99.0% |
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.50 | 32.0 | 3.71e-01 | 74.9% | 89.2% |
| 4o6mA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.50 | 41.0 | 4.00e-01 | 88.3% | 87.2% |
ECOD (42)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3838243 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.69 | 52.0 | 5.78e-01 | 79.5% | 100.0% |
| 3958339 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.69 | 37.0 | 4.31e-01 | 93.6% | 71.2% |
| 4976975 | 5001.1.1.12 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Heliorhodopsin | 0.66 | 58.0 | 5.19e-01 | 92.4% | 98.7% |
| 4931347 | 5001.1.1.12 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Heliorhodopsin | 0.66 | 56.0 | 4.84e-01 | 91.2% | 95.5% |
| 3934901 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.65 | 55.0 | 5.20e-01 | 90.6% | 99.5% |
| 3792670 | 633.21.1.10 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL | 0.64 | 36.0 | 3.99e-01 | 90.1% | 67.4% |
| 3581998 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.64 | 36.0 | 4.00e-01 | 90.1% | 68.1% |
| 4261817 | 5086.1.1.91 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PRM1 | 0.62 | 44.0 | 4.25e-01 | 72.5% | 83.5% |
| 4952530 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.62 | 37.0 | 4.09e-01 | 92.4% | 73.3% |
| 5046915 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.62 | 37.0 | 3.76e-01 | 91.8% | 58.2% |
| 4411923 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.61 | 55.0 | 5.13e-01 | 97.7% | 79.5% |
| 3387116 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.61 | 46.0 | 5.07e-01 | 90.6% | 100.0% |
| 4027037 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.59 | 50.0 | 4.38e-01 | 90.6% | 83.2% |
| 3940975 | 4177.2.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain | 0.58 | 42.0 | 3.50e-01 | 74.3% | 79.3% |
| 3734644 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.58 | 49.0 | 4.09e-01 | 90.1% | 87.5% |
| 3924754 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.58 | 48.0 | 3.71e-01 | 87.7% | 88.9% |
| 3174027 | 5001.1.1.32 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a | 0.57 | 52.0 | 4.40e-01 | 98.8% | 92.9% |
| 4034544 | 5067.1.1.6 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › YibE_F | 0.57 | 46.0 | 4.20e-01 | 86.5% | 63.0% |
| 4149055 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.57 | 39.0 | 3.72e-01 | 90.1% | 59.0% |
| 3386718 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 44.0 | 4.61e-01 | 84.2% | 88.7% |
| 3907394 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.55 | 46.0 | 3.85e-01 | 88.3% | 91.4% |
| 3483292 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 42.0 | 4.05e-01 | 80.1% | 71.3% |
| 3498895 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 39.0 | 4.26e-01 | 74.3% | 91.0% |
| 3221738 | 192.29.1.172 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 | 0.54 | 39.0 | 4.21e-01 | 73.1% | 92.1% |
| 3459347 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.54 | 42.0 | 4.16e-01 | 81.3% | 81.1% |
| 3346621 | 192.29.1.115 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF599 | 0.54 | 38.0 | 3.59e-01 | 91.8% | 59.5% |
| 4033880 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.53 | 39.0 | 3.70e-01 | 74.3% | 99.5% |
| 3464696 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.53 | 37.0 | 4.23e-01 | 72.5% | 95.4% |
| 3449357 | 150.1.1.110 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF7358 | 0.53 | 37.0 | 3.77e-01 | 91.8% | 71.8% |
| 3459287 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.53 | 38.0 | 3.92e-01 | 74.3% | 93.9% |
| 4283166 | 604.5.1.31 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TRAM_LAG1_CLN8 | 0.53 | 37.0 | 3.18e-01 | 70.8% | 83.9% |
| 3388784 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.52 | 36.0 | 4.15e-01 | 70.2% | 100.0% |
| 3840817 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.52 | 38.0 | 3.78e-01 | 73.1% | 99.4% |
| 3673192 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 41.0 | 4.20e-01 | 84.2% | 84.1% |
| 3225005 | 192.29.1.31 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CRIC_ras_sig | 0.51 | 37.0 | 4.11e-01 | 83.0% | 96.9% |
| 3995987 | 192.29.1.31 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CRIC_ras_sig | 0.51 | 38.0 | 4.07e-01 | 81.3% | 90.3% |
| 3629032 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.51 | 36.0 | 3.73e-01 | 73.7% | 83.0% |
| 3589119 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.51 | 42.0 | 3.77e-01 | 88.9% | 84.1% |
| 3577574 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.50 | 37.0 | 3.68e-01 | 94.7% | 72.2% |
| 3938853 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.50 | 44.0 | 3.97e-01 | 94.2% | 77.0% |
| 5056942 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.50 | 37.0 | 3.58e-01 | 77.8% | 100.0% |
| 3304001 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.50 | 37.0 | 4.03e-01 | 77.2% | 95.7% |