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Ig8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00645
Bact-VirIg8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00645
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 24-151
Domain cluster:
rep: LacPavin_0818_WC45_scaffold_160996_curated_closed_complete_prodigal-single.1__X__X__00783__D29-138
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6dgiA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.75 | 41.0 | 5.42e-01 | 75.0% | 100.0% |
| 1gsaA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.74 | 38.0 | 5.27e-01 | 74.2% | 100.0% |
| 1ekzA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.67 | 26.0 | 3.38e-01 | 91.4% | 60.5% |
| 3orqA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.67 | 35.0 | 4.61e-01 | 75.0% | 100.0% |
| 5i47B02 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.67 | 37.0 | 4.69e-01 | 75.8% | 100.0% |
| 3tqtA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.66 | 37.0 | 4.64e-01 | 84.4% | 100.0% |
| 2bv4A00 | 2.60.120.400 | Mainly Beta › Sandwich › Jelly Rolls › Calcium-mediated lectin | 0.64 | 36.0 | 3.84e-01 | 89.8% | 61.9% |
| 4mamA02 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.64 | 40.0 | 4.79e-01 | 87.5% | 97.5% |
| 1xffA00 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.63 | 38.0 | 3.08e-01 | 100.0% | 31.5% |
| 3d33A00 | 2.60.40.3080 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.61 | 40.0 | 4.55e-01 | 92.2% | 88.3% |
| 5iqlA00 | 2.60.40.1970 | Mainly Beta › Sandwich › Immunoglobulin-like › YEATS domain | 0.61 | 36.0 | 3.59e-01 | 90.6% | 56.2% |
| 4g5aA00 | 2.60.40.3080 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.60 | 35.0 | 3.93e-01 | 100.0% | 73.7% |
| 3rj2X00 | 2.60.120.1150 | Mainly Beta › Sandwich › Jelly Rolls › | 0.60 | 45.0 | 4.46e-01 | 100.0% | 74.4% |
| 5fmvA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.60 | 33.0 | 4.06e-01 | 99.2% | 83.3% |
| 4zfjD00 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.59 | 40.0 | 3.34e-01 | 74.2% | 39.2% |
| 1rlhA02 | 3.40.1520.10 | Alpha Beta › 3-Layer(aba) Sandwich › hypothetical protein tt1634 › Ta1353-like | 0.59 | 39.0 | 4.31e-01 | 73.4% | 84.2% |
| 2pn5A05 | 2.60.40.1930 | Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain | 0.59 | 35.0 | 3.94e-01 | 100.0% | 77.1% |
| 2xbzA00 | 2.60.40.2380 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.58 | 49.0 | 4.86e-01 | 90.6% | 85.6% |
| 1cbfA02 | 3.30.950.10 | Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain | 0.56 | 40.0 | 4.15e-01 | 98.4% | 78.5% |
| 4ev0D01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.55 | 32.0 | 3.18e-01 | 97.7% | 51.8% |
| 3mfiA04 | 3.30.1490.100 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain | 0.55 | 40.0 | 4.14e-01 | 75.8% | 95.0% |
| 1yb3A00 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.55 | 47.0 | 4.30e-01 | 98.4% | 70.3% |
| 2j1vA00 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.54 | 47.0 | 4.60e-01 | 93.8% | 84.4% |
| 6hj2A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.54 | 38.0 | 3.02e-01 | 72.7% | 86.9% |
| 3nutB02 | 3.30.950.10 | Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain | 0.54 | 39.0 | 3.98e-01 | 96.1% | 75.0% |
| 1yq2A04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 36.0 | 3.79e-01 | 100.0% | 74.8% |
| 1burS00 | 3.30.190.10 | Alpha Beta › 2-Layer Sandwich › Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase › Ribulose bisphosphate carboxylase, small subunit | 0.54 | 39.0 | 4.04e-01 | 90.6% | 78.9% |
| 3cu7A05 | 2.60.40.1930 | Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain | 0.54 | 35.0 | 3.81e-01 | 100.0% | 78.3% |
| 5jtwA02 | 2.60.40.1930 | Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain | 0.54 | 35.0 | 3.88e-01 | 100.0% | 83.0% |
| 1bkjA00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.53 | 49.0 | 4.02e-01 | 100.0% | 57.0% |
| 3f6kA02 | 2.10.70.80 | Mainly Beta › Ribbon › Complement Module; domain 1 › Sortilin Vps10-D, 10CC-a domain | 0.53 | 24.0 | 3.40e-01 | 93.8% | 93.0% |
| 5hccB02 | 2.60.40.1930 | Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain | 0.53 | 35.0 | 3.95e-01 | 100.0% | 89.5% |
| 2wq4A01 | 2.60.120.760 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 42.0 | 4.24e-01 | 94.5% | 84.5% |
| 2a74A05 | 2.60.40.1930 | Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain | 0.53 | 34.0 | 3.74e-01 | 100.0% | 80.0% |
| 2jvuA00 | 2.60.40.2290 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.52 | 33.0 | 3.72e-01 | 100.0% | 82.7% |
| 4mi7A00 | 3.90.70.170 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › | 0.52 | 39.0 | 3.99e-01 | 100.0% | 81.5% |
| 3m70A01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.52 | 36.0 | 3.95e-01 | 78.1% | 87.7% |
| 3u0aA00 | 2.40.160.210 | Mainly Beta › Beta Barrel › Porin › Acyl-CoA thioesterase, double hotdog domain | 0.52 | 38.0 | 3.09e-01 | 78.1% | 88.3% |
| 3pz8C00 | 2.40.240.130 | Mainly Beta › Beta Barrel › Ribosomal Protein L25; Chain P › | 0.52 | 32.0 | 3.82e-01 | 90.6% | 98.8% |
| 3lwkA02 | 2.60.20.10 | Mainly Beta › Sandwich › Gamma-B Crystallin; domain 1 › Crystallins | 0.51 | 35.0 | 3.97e-01 | 100.0% | 96.7% |
| 1pvgA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.51 | 47.0 | 3.77e-01 | 100.0% | 57.4% |
| 3enuA00 | 2.60.20.10 | Mainly Beta › Sandwich › Gamma-B Crystallin; domain 1 › Crystallins | 0.51 | 37.0 | 3.88e-01 | 99.2% | 86.0% |
| 4ekuA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.50 | 36.0 | 3.80e-01 | 94.5% | 82.1% |
| 2aehA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.50 | 35.0 | 3.94e-01 | 94.5% | 96.9% |
| 2q3xA00 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.50 | 36.0 | 3.55e-01 | 95.3% | 67.6% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4165803 | 206.1.3.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › GSH-S_ATP | 0.72 | 41.0 | 3.58e-01 | 87.5% | 36.9% |
| None | — | 0.71 | 41.0 | 3.57e-01 | 87.5% | 37.4% | |
| 4195948 | 206.1.3.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › GSH-S_ATP | 0.70 | 41.0 | 3.56e-01 | 87.5% | 38.4% |
| 5054721 | 210.1.3.3 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 | 0.70 | 42.0 | 3.42e-01 | 75.8% | 31.7% |
| 4408163 | 206.1.3.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › GSH-S_ATP | 0.70 | 40.0 | 3.52e-01 | 87.5% | 38.4% |
| 4929079 | 821.1.1.15 ↗ | a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › DUF7508 | 0.69 | 37.0 | 4.29e-01 | 84.4% | 71.3% |
| 5075402 | 210.1.3.3 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 | 0.68 | 42.0 | 3.26e-01 | 75.0% | 28.1% |
| 4639481 | 206.1.3.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › GSH-S_ATP | 0.67 | 40.0 | 3.51e-01 | 89.1% | 40.0% |
| 5011065 | 206.1.3.21 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RimK | 0.65 | 40.0 | 3.43e-01 | 88.3% | 38.0% |
| 5027271 | 210.1.3.3 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 | 0.65 | 42.0 | 3.39e-01 | 74.2% | 33.2% |
| 4947430 | 206.1.3.21 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RimK | 0.65 | 40.0 | 3.46e-01 | 88.3% | 39.0% |
| 4991572 | 210.1.3.5 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 | 0.65 | 42.0 | 3.45e-01 | 99.2% | 35.4% |
| 4976794 | 210.1.3.5 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 | 0.63 | 39.0 | 3.22e-01 | 75.8% | 33.9% |
| 5046503 | 206.1.3.21 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RimK | 0.63 | 39.0 | 3.35e-01 | 89.1% | 39.5% |
| 5000173 | 206.1.3.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL | 0.61 | 42.0 | 3.36e-01 | 88.3% | 34.6% |
| 4107956 | 1137.1.1.0 ↗ | a+b two layers › Tetrapyrrole methylase C-terminal domain-like › Tetrapyrrole methylase C-terminal domain › Tetrapyrrole methylase C-terminal domain | 0.61 | 43.0 | 4.46e-01 | 98.4% | 77.5% |
| 5055293 | 10.1.2.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) | 0.60 | 35.0 | 4.14e-01 | 99.2% | 85.9% |
| 4398420 | 1137.1.1.0 ↗ | a+b two layers › Tetrapyrrole methylase C-terminal domain-like › Tetrapyrrole methylase C-terminal domain › Tetrapyrrole methylase C-terminal domain | 0.59 | 42.0 | 4.38e-01 | 98.4% | 78.3% |
| 3782814 | 210.1.3.3 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 | 0.59 | 41.0 | 3.18e-01 | 75.0% | 31.6% |
| 5082445 | 10.1.2.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) | 0.58 | 41.0 | 4.41e-01 | 94.5% | 84.5% |
| 5077548 | 210.1.3.0 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases | 0.58 | 42.0 | 3.21e-01 | 99.2% | 32.5% |
| 3419007 | 821.1.1.0 ↗ | a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease | 0.58 | 35.0 | 3.71e-01 | 77.3% | 66.1% |
| 3710219 | 206.1.3.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL | 0.58 | 41.0 | 2.98e-01 | 89.8% | 25.8% |
| 5011692 | 10.1.2.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) | 0.58 | 45.0 | 4.23e-01 | 99.2% | 68.4% |
| 3908517 | 10.4.1.1 ↗ | beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › CUB | 0.57 | 42.0 | 4.39e-01 | 92.2% | 84.3% |
| 3177841 | 221.1.1.52 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Ubiquitin_2 | 0.57 | 38.0 | 4.30e-01 | 91.4% | 95.6% |
| 146929 | 3115.3.1.1 ↗ | a+b two layers › GP2-like › P56 › P56 › UDG-inhib_P56 | 0.56 | 25.0 | 3.55e-01 | 76.6% | 92.9% |
| 5061005 | 10.1.2.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) | 0.56 | 43.0 | 4.32e-01 | 99.2% | 80.0% |
| 4030677 | 1116.1.1.0 ↗ | a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain | 0.56 | 44.0 | 4.18e-01 | 100.0% | 70.7% |
| 4033790 | 1137.1.1.1 ↗ | a+b two layers › Tetrapyrrole methylase C-terminal domain-like › Tetrapyrrole methylase C-terminal domain › Tetrapyrrole methylase C-terminal domain › TP_methylase | 0.56 | 40.0 | 4.04e-01 | 98.4% | 75.2% |
| 3608101 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.56 | 31.0 | 3.54e-01 | 100.0% | 72.6% |
| 3290160 | 4.1.1.323 ↗ | beta barrels › SH3 › SH3 › SH3 › WYL | 0.55 | 34.0 | 4.21e-01 | 85.2% | 100.0% |
| 4000111 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.53 | 37.0 | 3.10e-01 | 90.6% | 40.0% |
| 4926800 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 37.0 | 4.01e-01 | 100.0% | 85.7% |
| 4328812 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.53 | 36.0 | 2.60e-01 | 90.6% | 22.8% |
| 3028533 | 188.1.1.0 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain | 0.53 | 38.0 | 2.94e-01 | 73.4% | 82.8% |
| 4120485 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.53 | 38.0 | 2.71e-01 | 73.4% | 65.9% |
| 3939178 | 304.48.1.37 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_2 | 0.53 | 34.0 | 3.04e-01 | 94.5% | 45.9% |
| 4356447 | 329.1.1.1 ↗ | a+b two layers › Prokaryotic AspRS, insert domain › Prokaryotic AspRS, insert domain › Prokaryotic AspRS, insert domain › GAD | 0.52 | 35.0 | 3.51e-01 | 82.0% | 66.9% |