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Ig8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00941
Bact-VirIg8144_scaffold_2_curated_closed_complete_start-adj_prodigal-single.1__X__X__00941
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 21-79_184-197
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.82 | 60.0 | 5.64e-01 | 76.7% | 69.0% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.82 | 74.0 | 6.03e-01 | 100.0% | 91.7% |
| 2yevC00 | 6.10.280.110 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 56.0 | 5.98e-01 | 71.2% | 96.8% |
| 2r9iA00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.82 | 59.0 | 5.99e-01 | 75.3% | 78.9% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.81 | 60.0 | 5.87e-01 | 78.1% | 79.7% |
| 2cazC00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.80 | 58.0 | 6.16e-01 | 78.1% | 85.9% |
| 6bl6B01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.80 | 61.0 | 3.89e-01 | 80.8% | 20.6% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.79 | 58.0 | 4.95e-01 | 78.1% | 52.1% |
| 2ra1A01 | 1.20.58.790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 63.0 | 5.66e-01 | 86.3% | 94.9% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 57.0 | 5.77e-01 | 79.5% | 83.6% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 58.0 | 5.75e-01 | 80.8% | 77.6% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 57.0 | 3.93e-01 | 79.5% | 26.3% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.74 | 64.0 | 5.90e-01 | 95.9% | 96.8% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.74 | 65.0 | 5.11e-01 | 100.0% | 63.2% |
| 1t7sA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.74 | 55.0 | 4.52e-01 | 79.5% | 48.1% |
| 3zbhA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.74 | 52.0 | 4.92e-01 | 75.3% | 85.6% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.73 | 64.0 | 5.34e-01 | 98.6% | 82.0% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 51.0 | 5.58e-01 | 74.0% | 96.6% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 54.0 | 5.69e-01 | 78.1% | 92.2% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 53.0 | 4.98e-01 | 79.5% | 68.5% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.72 | 62.0 | 5.33e-01 | 97.3% | 84.0% |
| 3pjaJ01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.72 | 63.0 | 5.27e-01 | 100.0% | 72.5% |
| 1ya0A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.72 | 58.0 | 4.20e-01 | 89.0% | 42.7% |
| 2y1vA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.72 | 61.0 | 4.56e-01 | 94.5% | 54.6% |
| 1rtwB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.72 | 52.0 | 3.73e-01 | 76.7% | 81.7% |
| 5mlc900 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.72 | 62.0 | 5.54e-01 | 98.6% | 96.3% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.72 | 50.0 | 5.43e-01 | 74.0% | 88.5% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.71 | 58.0 | 5.48e-01 | 90.4% | 86.5% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.71 | 57.0 | 5.44e-01 | 87.7% | 74.1% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.71 | 62.0 | 5.38e-01 | 97.3% | 92.8% |
| 2ewfA02 | 1.20.1270.310 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.70 | 48.0 | 4.63e-01 | 72.6% | 63.0% |
| 2kkmA01 | 1.20.1440.170 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Translation machinery-associated protein 16-like | 0.70 | 51.0 | 4.25e-01 | 80.8% | 44.8% |
| 1wrdA00 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 63.0 | 5.71e-01 | 100.0% | 94.9% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 51.0 | 4.25e-01 | 78.1% | 45.4% |
| 1chuA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.69 | 57.0 | 5.43e-01 | 93.2% | 86.4% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.69 | 51.0 | 4.08e-01 | 79.5% | 40.7% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 59.0 | 5.10e-01 | 100.0% | 95.8% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.67 | 57.0 | 4.86e-01 | 97.3% | 74.0% |
| 3tp3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 55.0 | 4.44e-01 | 98.6% | 59.5% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.64 | 44.0 | 4.32e-01 | 75.3% | 65.4% |
| 2p6rA03 | 1.10.3380.30 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › | 0.61 | 47.0 | 3.45e-01 | 86.3% | 59.2% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.60 | 51.0 | 3.74e-01 | 97.3% | 52.6% |
| 4b4yA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.56 | 45.0 | 3.61e-01 | 89.0% | 85.2% |
| 4ii2A02 | 3.40.50.12550 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2 | 0.54 | 42.0 | 3.06e-01 | 86.3% | 35.0% |
| 2oyyA00 | 6.10.80.10 | Special › Helix non-globular › DNA polymerase; domain 1 › Hexameric tyrosine-coordinated heme protein (HTHP) | 0.52 | 36.0 | 3.66e-01 | 72.6% | 91.5% |
ECOD (62)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3312910 | 603.1.1.111 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › TBCC_N | 0.87 | 80.0 | 7.36e-01 | 97.3% | 97.8% |
| 3907213 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.86 | 75.0 | 6.67e-01 | 93.2% | 97.0% |
| 3405261 | 604.22.1.1 ↗ | alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain › TBCC_N | 0.85 | 78.0 | 6.46e-01 | 98.6% | 74.2% |
| 3733626 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.83 | 72.0 | 5.78e-01 | 95.9% | 73.6% |
| 3990182 | 3922.1.1.226 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Fy-3 | 0.83 | 64.0 | 5.39e-01 | 80.8% | 58.3% |
| 3518386 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.83 | 60.0 | 5.94e-01 | 75.3% | 76.0% |
| 3491738 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.82 | 63.0 | 5.62e-01 | 80.8% | 77.8% |
| 3837777 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.82 | 69.0 | 6.05e-01 | 90.4% | 89.5% |
| 3619200 | 192.15.1.76 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › CUPID | 0.81 | 58.0 | 4.48e-01 | 75.3% | 36.8% |
| 5004570 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.80 | 64.0 | 6.37e-01 | 86.3% | 100.0% |
| 4959990 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.80 | 72.0 | 5.89e-01 | 98.6% | 80.8% |
| 3194769 | 109.4.1.148 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EST1_DNA_bind,EST1 | 0.80 | 70.0 | 4.08e-01 | 95.9% | 14.8% |
| 3491806 | 101.1.1.3 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-binding | 0.79 | 59.0 | 3.75e-01 | 79.5% | 18.5% |
| 3375742 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.78 | 66.0 | 5.01e-01 | 91.8% | 63.0% |
| 2474689 | 192.13.1.1 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like › Isy1 | 0.78 | 55.0 | 5.60e-01 | 74.0% | 76.1% |
| 3479092 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.78 | 67.0 | 5.98e-01 | 93.2% | 86.0% |
| 4959083 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.77 | 70.0 | 5.26e-01 | 100.0% | 89.4% |
| 3927597 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.77 | 69.0 | 5.82e-01 | 100.0% | 95.8% |
| 3969538 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.77 | 54.0 | 6.05e-01 | 74.0% | 98.2% |
| 3967403 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.77 | 56.0 | 5.94e-01 | 78.1% | 90.8% |
| 3618523 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.77 | 55.0 | 5.12e-01 | 75.3% | 63.3% |
| 4146694 | 192.29.1.277 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Dynamitin | 0.77 | 55.0 | 5.79e-01 | 75.3% | 84.6% |
| 4027991 | 4984.1.1.0 ↗ | alpha bundles › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain | 0.77 | 66.0 | 6.00e-01 | 93.2% | 91.6% |
| 4822938 | 4031.1.1.1 ↗ | a+b three layers › Nigritoxin middle domain › Nigritoxin middle domain › Nigritoxin middle domain › Flagellin_N,Flagellin_C | 0.76 | 67.0 | 5.08e-01 | 98.6% | 62.6% |
| 3632592 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.76 | 67.0 | 5.49e-01 | 97.3% | 89.2% |
| 3175197 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.76 | 56.0 | 4.59e-01 | 80.8% | 43.8% |
| 3605711 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.76 | 67.0 | 6.52e-01 | 97.3% | 98.8% |
| 4349607 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.76 | 58.0 | 5.00e-01 | 80.8% | 82.7% |
| 3968484 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.76 | 56.0 | 5.71e-01 | 78.1% | 88.6% |
| 3892495 | 604.1.1.7 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 | 0.76 | 67.0 | 5.70e-01 | 100.0% | 90.8% |
| 3483476 | 192.13.1.0 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like | 0.76 | 65.0 | 5.65e-01 | 94.5% | 82.7% |
| 3785849 | 192.13.1.1 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like › Isy1 | 0.75 | 65.0 | 5.26e-01 | 94.5% | 72.6% |
| 3244235 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.75 | 67.0 | 6.00e-01 | 97.3% | 88.0% |
| 5084060 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.75 | 56.0 | 4.38e-01 | 79.5% | 70.3% |
| 4990095 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.75 | 64.0 | 6.13e-01 | 95.9% | 92.9% |
| 3783731 | 2004.1.1.505 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11, AAA_30 | 0.75 | 53.0 | 3.30e-01 | 75.3% | 13.6% |
| 1878710 | 4970.1.1.1 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.74 | 52.0 | 5.73e-01 | 72.6% | 94.6% |
| 2456957 | 192.13.1.1 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like › Isy1 | 0.74 | 52.0 | 5.80e-01 | 74.0% | 100.0% |
| 4998508 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.74 | 62.0 | 4.61e-01 | 93.2% | 61.1% |
| 3314545 | 4030.1.1.0 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz | 0.74 | 57.0 | 5.93e-01 | 93.2% | 93.8% |
| 3197870 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.74 | 66.0 | 5.40e-01 | 100.0% | 85.2% |
| 4357799 | 192.13.1.1 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like › Isy1 | 0.74 | 63.0 | 5.21e-01 | 94.5% | 70.0% |
| 3514683 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.73 | 65.0 | 5.72e-01 | 100.0% | 97.3% |
| 3980912 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.73 | 62.0 | 5.37e-01 | 95.9% | 71.3% |
| 3172093 | 604.1.1.132 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › KAR9 | 0.73 | 62.0 | 5.24e-01 | 95.9% | 74.4% |
| 3243897 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.73 | 65.0 | 5.19e-01 | 98.6% | 90.7% |
| 3813837 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.72 | 54.0 | 5.37e-01 | 79.5% | 96.0% |
| 4940797 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 63.0 | 5.97e-01 | 95.9% | 98.8% |
| 3981661 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.72 | 63.0 | 5.91e-01 | 97.3% | 94.4% |
| 4496877 | 3755.3.1.284 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Utp11 | 0.71 | 50.0 | 4.12e-01 | 75.3% | 60.0% |
| 3281127 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.70 | 52.0 | 4.91e-01 | 79.5% | 65.6% |
| 3297464 | 601.1.3.2 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › GCIP_N | 0.69 | 56.0 | 4.53e-01 | 93.2% | 56.1% |
| 3683741 | 192.13.1.1 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like › Isy1 | 0.69 | 59.0 | 5.52e-01 | 94.5% | 76.7% |
| 5029140 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.69 | 56.0 | 5.19e-01 | 87.7% | 93.3% |
| 5046133 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.69 | 62.0 | 5.75e-01 | 98.6% | 98.9% |
| 5039404 | 604.2.1.0 ↗ | alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 0.68 | 57.0 | 5.71e-01 | 93.2% | 97.3% |
| 3780651 | 3602.1.1.0 ↗ | alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain | 0.68 | 49.0 | 5.10e-01 | 78.1% | 95.4% |
| 140849 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.64 | 55.0 | 4.43e-01 | 98.6% | 72.8% |
| 4527464 | 633.24.1.5 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › PF29080 | 0.63 | 50.0 | 4.62e-01 | 87.7% | 85.3% |
| 3607719 | 633.24.1.0 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain | 0.63 | 50.0 | 4.80e-01 | 89.0% | 83.5% |
| 3781505 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.61 | 51.0 | 3.47e-01 | 97.3% | 93.7% |
| 4623473 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.58 | 50.0 | 3.27e-01 | 100.0% | 61.4% |
D2
high
residues 83-179
Domain cluster:
rep: Mad1_20_16_scaffold_0_curated_closed_complete_start-adj_prodigal-single.1__X__X__00285__D81-177
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2mx8A01 | 1.10.274.70 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain | 0.62 | 53.0 | 5.07e-01 | 95.9% | 100.0% |
| 6ne6A01 | 1.10.400.10 | Mainly Alpha › Orthogonal Bundle › GI Alpha 1, domain 2-like › GI Alpha 1, domain 2-like | 0.62 | 54.0 | 5.14e-01 | 99.0% | 82.5% |
| 3i2fA02 | 1.10.3020.10 | Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) | 0.58 | 40.0 | 4.10e-01 | 87.6% | 72.6% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.58 | 42.0 | 4.44e-01 | 92.8% | 83.1% |
| 1gcvB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 51.0 | 4.59e-01 | 100.0% | 100.0% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 47.0 | 4.07e-01 | 89.7% | 77.7% |
| 1ze0A02 | 1.10.4070.10 | Mainly Alpha › Orthogonal Bundle › putative redox-enzyme maturation protein fold › putative redox-enzyme maturation protein domain | 0.57 | 38.0 | 4.15e-01 | 97.9% | 84.6% |
| 1vsy300 | 1.10.287.2210 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 30.0 | 3.41e-01 | 92.8% | 65.8% |
| 5es8A03 | 1.10.1200.10 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like | 0.56 | 33.0 | 3.77e-01 | 92.8% | 77.8% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 46.0 | 4.61e-01 | 92.8% | 92.2% |
| 1gcvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 48.0 | 4.32e-01 | 100.0% | 100.0% |
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.54 | 41.0 | 3.56e-01 | 81.4% | 88.5% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.54 | 42.0 | 4.48e-01 | 96.9% | 100.0% |
| 3nrhA00 | 1.20.120.1550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Protein of unknown function DUF5063 | 0.54 | 37.0 | 3.20e-01 | 70.1% | 90.5% |
| 5af7B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 46.0 | 4.06e-01 | 100.0% | 91.2% |
| 3qf3D00 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.53 | 38.0 | 3.54e-01 | 93.8% | 58.6% |
| 2jnsA01 | 1.20.1270.220 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 35.0 | 3.82e-01 | 72.2% | 84.0% |
| 4lqkA00 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.52 | 42.0 | 3.84e-01 | 89.7% | 75.0% |
| 3fvvA02 | 1.20.1440.100 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › SG protein - dephosphorylation function | 0.50 | 34.0 | 3.78e-01 | 70.1% | 97.3% |
| 5ja4D00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.50 | 40.0 | 3.48e-01 | 85.6% | 69.1% |
| 3lxzB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.50 | 40.0 | 3.60e-01 | 92.8% | 60.9% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3851172 | 150.3.1.14 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL5 | 0.64 | 48.0 | 5.27e-01 | 100.0% | 97.5% |
| 3215515 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.63 | 43.0 | 4.49e-01 | 70.1% | 88.9% |
| 4175767 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.63 | 43.0 | 4.25e-01 | 71.1% | 89.5% |
| 3231735 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.62 | 55.0 | 4.53e-01 | 100.0% | 90.3% |
| 3521510 | 192.7.1.73 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › PF31020 | 0.62 | 47.0 | 4.58e-01 | 82.5% | 92.7% |
| 3876932 | 592.3.1.8 ↗ | alpha arrays › PWI domain-like › N-terminal domain of egg case silk protein TuSp1 › N-terminal domain of egg case silk protein TuSp1 › PF31020 | 0.58 | 45.0 | 4.46e-01 | 83.5% | 98.1% |
| 3182958 | 101.1.1.64 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › tRNA_bind_2 | 0.58 | 43.0 | 3.89e-01 | 79.4% | 67.4% |
| 3523225 | 5059.1.1.4 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Nuc_sug_transp | 0.57 | 49.0 | 3.44e-01 | 94.8% | 70.3% |
| 3988434 | 633.2.1.0 ↗ | alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein | 0.56 | 48.0 | 4.73e-01 | 95.9% | 92.3% |
| 3642518 | 5059.1.1.33 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, SLC35F | 0.56 | 48.0 | 3.51e-01 | 100.0% | 93.1% |
| 3784235 | 5059.1.1.5 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA | 0.56 | 48.0 | 3.45e-01 | 99.0% | 76.6% |
| 3916461 | 5059.1.1.5 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA | 0.55 | 47.0 | 3.34e-01 | 94.8% | 69.0% |
| 3433446 | 109.4.1.1257 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 | 0.54 | 40.0 | 2.90e-01 | 79.4% | 36.4% |
| 3692550 | 3525.1.1.1 ↗ | alpha arrays › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › BET | 0.53 | 35.0 | 3.99e-01 | 70.1% | 94.3% |
| 4299757 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.53 | 46.0 | 3.27e-01 | 99.0% | 76.9% |
| 3624127 | 5059.1.1.5 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA | 0.52 | 45.0 | 3.20e-01 | 97.9% | 87.4% |
| 4272227 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.52 | 45.0 | 3.30e-01 | 100.0% | 96.0% |
| 3249649 | 5059.1.1.3 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT | 0.52 | 44.0 | 3.18e-01 | 99.0% | 93.3% |
| 3992022 | 5059.1.1.5 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA | 0.52 | 45.0 | 3.25e-01 | 96.9% | 89.7% |
| 3212929 | 3525.1.1.1 ↗ | alpha arrays › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › BET | 0.52 | 35.0 | 4.04e-01 | 71.1% | 100.0% |
| 1758745 | 2004.1.1.221 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › P-loop_TraG | 0.51 | 38.0 | 3.14e-01 | 99.0% | 41.6% |