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AGF91196.1

Arc-Vir

JF974305__AGF91196.1__HAPG-00010__00010

Identity

Accession:
JF974305 ↗
Protein ID:
AGF91196.1 ↗
Kingdom:
archaea

Quality

78.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-84_185-211
PDB
CATH (63)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2od4B01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.79 54.0 5.95e-01 97.3% 86.5%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.78 49.0 4.21e-01 97.3% 41.3%
1yz7A02 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.74 52.0 5.63e-01 100.0% 87.8%
2cveA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.73 40.0 5.00e-01 96.4% 89.4%
3uebF00 3.30.300.100 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like 0.72 60.0 6.24e-01 98.2% 97.0%
1xmbA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 52.0 5.41e-01 100.0% 82.2%
1q8kA03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.72 49.0 4.83e-01 100.0% 66.4%
2ahoB03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.69 49.0 5.35e-01 100.0% 92.0%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 47.0 5.03e-01 98.2% 82.3%
1y0hB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 47.0 4.94e-01 99.1% 80.6%
4bbyA05 3.30.300.330 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.67 51.0 5.13e-01 97.3% 81.5%
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 44.0 4.95e-01 90.0% 88.2%
3bguA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 47.0 5.04e-01 99.1% 87.5%
7xinA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.64 42.0 4.29e-01 97.3% 67.9%
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 37.0 4.28e-01 92.7% 82.4%
2plgA01 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.64 45.0 4.23e-01 100.0% 60.6%
3hr6A02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.64 43.0 3.79e-01 100.0% 47.8%
3aawA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.63 40.0 3.49e-01 90.0% 41.8%
1ry9A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.63 44.0 4.20e-01 96.4% 60.9%
1xkpB00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.63 42.0 4.16e-01 94.5% 62.8%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.62 44.0 4.20e-01 100.0% 62.3%
1dq3A04 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.62 35.0 3.53e-01 86.4% 52.6%
2jvrA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 37.0 4.25e-01 96.4% 83.7%
5fiiB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.61 38.0 4.36e-01 93.6% 88.5%
3go9A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.61 52.0 4.14e-01 92.7% 76.5%
2anrA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.60 39.0 4.58e-01 100.0% 97.3%
1f3vA00 3.30.70.680 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TRADD, N-terminal domain 0.60 48.0 4.30e-01 98.2% 60.1%
2fm8B00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.60 43.0 4.19e-01 100.0% 66.4%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.60 38.0 4.04e-01 97.3% 73.7%
6i3gA02 3.90.76.10 Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 0.59 44.0 4.30e-01 99.1% 72.0%
4gf3A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.58 37.0 3.61e-01 95.5% 57.7%
3girA02 3.30.70.1400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aminomethyltransferase beta-barrel domains 0.57 41.0 4.52e-01 97.3% 95.3%
1xocA02 3.90.76.10 Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 0.57 41.0 4.06e-01 99.1% 70.0%
2di7A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 38.0 3.92e-01 93.6% 71.0%
1vx7H01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.56 39.0 4.35e-01 100.0% 95.3%
1zu0A02 3.90.76.10 Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 0.56 39.0 3.97e-01 99.1% 73.8%
4g0bA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.56 49.0 4.03e-01 98.2% 68.3%
4paaA04 3.30.70.1400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aminomethyltransferase beta-barrel domains 0.56 40.0 3.92e-01 99.1% 69.2%
2uv8A06 3.30.70.2490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 27.0 3.27e-01 86.4% 70.1%
4hvmB01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.55 47.0 4.01e-01 95.5% 67.6%
4pfyA02 3.90.76.10 Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 0.55 39.0 3.62e-01 98.2% 55.8%
4y2fA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.55 41.0 3.79e-01 79.1% 87.4%
5u89A02 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.55 49.0 4.30e-01 100.0% 76.5%
5x68A00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 37.0 2.61e-01 96.4% 21.2%
3w9kA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.54 48.0 4.52e-01 100.0% 94.1%
1k8kD01 3.30.1460.20 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.54 44.0 4.01e-01 99.1% 65.6%
7emyA02 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.53 44.0 3.92e-01 91.8% 76.5%
3cx5A01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.53 46.0 3.76e-01 94.5% 73.3%
6l3tA01 1.20.1440.80 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain 0.53 41.0 3.48e-01 85.5% 78.4%
5swsE01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 39.0 3.94e-01 100.0% 76.6%
3dbaA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.53 39.0 3.38e-01 78.2% 89.5%
3rghA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 34.0 3.66e-01 93.6% 76.0%
5mmiG01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.53 38.0 4.15e-01 100.0% 98.8%
5y6iA02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.52 40.0 3.50e-01 80.0% 100.0%
5l10B00 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.52 38.0 3.31e-01 76.4% 88.8%
1vw4F02 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.52 36.0 3.86e-01 100.0% 84.8%
2avxA00 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.52 39.0 3.36e-01 79.1% 87.1%
4zxhA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.52 43.0 3.80e-01 94.5% 73.0%
4zxwB01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.52 45.0 3.92e-01 98.2% 78.5%
6cc0A01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.51 38.0 3.36e-01 79.1% 91.5%
3obfA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.51 40.0 3.48e-01 86.4% 97.7%
4uoyA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.51 42.0 3.45e-01 100.0% 49.5%
2g7uC02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.51 39.0 3.41e-01 84.5% 98.9%
ECOD (89)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4061057 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.79 56.0 6.09e-01 100.0% 88.9%
4317294 207.11.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.77 51.0 3.81e-01 100.0% 27.9%
4316518 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.77 54.0 5.91e-01 100.0% 88.9%
5048109 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.76 53.0 5.73e-01 100.0% 87.8%
5027042 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.75 50.0 5.49e-01 100.0% 84.1%
4983053 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.75 52.0 5.75e-01 100.0% 91.8%
5031564 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.75 51.0 5.53e-01 100.0% 83.9%
3738266 2004.1.1.433 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 0.74 61.0 3.82e-01 88.2% 58.5%
3698765 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.73 51.0 5.24e-01 100.0% 76.2%
5028560 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.72 58.0 5.88e-01 100.0% 85.5%
5030091 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.72 49.0 5.40e-01 100.0% 89.4%
5035888 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.72 50.0 5.51e-01 100.0% 91.8%
4611212 207.11.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.72 45.0 3.35e-01 96.4% 25.9%
4934098 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.71 49.0 5.39e-01 100.0% 90.6%
984477 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.69 55.0 5.82e-01 97.3% 94.9%
3488179 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.69 49.0 5.38e-01 100.0% 91.1%
3825541 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.68 47.0 4.77e-01 100.0% 70.9%
3907671 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.68 40.0 4.70e-01 93.6% 85.3%
5040845 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.68 50.0 5.19e-01 100.0% 84.0%
3936869 304.8.1.72 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › SCVP 0.68 48.0 5.04e-01 93.6% 81.8%
4240079 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.67 47.0 4.96e-01 97.3% 80.0%
5054097 305.1.1.10 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › PF27806 0.67 45.0 4.96e-01 100.0% 87.1%
4976198 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.67 46.0 5.13e-01 70.0% 100.0%
2137705 304.159.1.1 a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › Lant_dehydr_C 0.67 45.0 5.18e-01 100.0% 97.4%
5049975 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.67 48.0 3.58e-01 75.5% 57.6%
5033558 304.120.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.66 38.0 4.56e-01 93.6% 87.1%
3584599 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.66 44.0 4.49e-01 100.0% 68.2%
5074889 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.66 53.0 5.68e-01 97.3% 100.0%
4981301 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.66 48.0 5.12e-01 97.3% 88.4%
4995243 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.66 44.0 5.07e-01 100.0% 100.0%
5039535 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.66 44.0 4.87e-01 100.0% 88.2%
5017844 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.66 55.0 5.40e-01 100.0% 83.3%
4964986 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.65 48.0 5.04e-01 100.0% 85.0%
3195155 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.65 41.0 4.82e-01 97.3% 100.0%
3289139 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.64 50.0 4.97e-01 100.0% 79.1%
4634265 207.11.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.64 46.0 3.53e-01 98.2% 30.7%
3783788 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.63 54.0 3.90e-01 92.7% 77.0%
3602384 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.63 51.0 5.03e-01 100.0% 82.5%
3839278 304.15.1.0 a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain 0.63 49.0 4.81e-01 93.6% 76.7%
3590341 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.62 55.0 4.60e-01 97.3% 81.9%
4629319 304.55.1.13 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Relaxase 0.62 47.0 4.61e-01 100.0% 73.3%
3486431 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 53.0 3.80e-01 92.7% 76.5%
3591115 304.163.1.0 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.62 45.0 4.74e-01 98.2% 86.0%
5055962 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.61 51.0 5.04e-01 100.0% 85.0%
3545474 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.61 44.0 4.71e-01 100.0% 92.2%
3164823 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.61 52.0 4.12e-01 94.5% 70.9%
4928161 331.10.2.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.60 49.0 5.16e-01 97.3% 97.0%
5060761 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.60 45.0 4.63e-01 96.4% 83.8%
3839195 304.55.1.13 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Relaxase 0.59 48.0 4.19e-01 100.0% 57.6%
3485236 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.59 51.0 4.70e-01 93.6% 75.7%
5063044 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.59 51.0 4.38e-01 94.5% 83.4%
5078624 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.59 47.0 4.86e-01 95.5% 93.3%
5581 306.8.1.1 a+b two layers › Glucose permease domain IIB-like › TM1457-like › TM1457-like › Peptidase_Prp 0.59 45.0 4.51e-01 99.1% 81.2%
3270493 304.42.1.1 a+b two layers › Alpha-beta plaits › Molybdenum cofactor biosynthesis protein C, MoaC › Molybdenum cofactor biosynthesis protein C, MoaC › MoaC 0.58 51.0 4.46e-01 100.0% 72.4%
3372265 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.57 44.0 4.41e-01 100.0% 79.1%
3722375 4955.1.1.0 a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.57 45.0 4.51e-01 95.5% 82.7%
3484611 331.3.1.6 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PRELI 0.57 50.0 4.40e-01 100.0% 98.2%
3225917 2498.1.1.23 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M49 0.57 49.0 3.08e-01 100.0% 94.3%
3222359 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.57 46.0 4.64e-01 87.3% 96.3%
5043799 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.56 50.0 4.97e-01 100.0% 94.1%
4321285 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.56 49.0 4.29e-01 98.2% 77.1%
3485848 304.47.1.0 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain 0.55 44.0 4.66e-01 88.2% 100.0%
3225343 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.55 49.0 4.20e-01 100.0% 93.9%
3317118 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.55 45.0 3.27e-01 90.9% 57.6%
3959377 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.55 48.0 4.24e-01 99.1% 78.2%
3957173 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.55 47.0 3.85e-01 95.5% 59.5%
4929336 331.3.1.11 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.55 48.0 4.37e-01 100.0% 92.3%
4048083 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.55 48.0 3.94e-01 99.1% 86.2%
1211453 2498.1.1.23 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M49 0.55 47.0 2.95e-01 100.0% 94.6%
3015534 304.48.1.12 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol 0.55 49.0 3.34e-01 100.0% 43.5%
3966435 7581.1.1.3 a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › ketoacyl-synt,Ketoacyl-synt_C 0.54 43.0 2.79e-01 89.1% 93.5%
3691833 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.54 48.0 3.97e-01 100.0% 73.2%
4045878 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.54 47.0 4.04e-01 98.2% 67.0%
5009503 331.3.1.7 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › COXG 0.54 48.0 4.47e-01 100.0% 98.6%
1173387 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.54 47.0 4.26e-01 98.2% 83.6%
3973522 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.54 47.0 3.99e-01 100.0% 67.2%
3967308 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.54 43.0 3.81e-01 87.3% 100.0%
4955870 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.54 41.0 3.58e-01 83.6% 92.8%
4585085 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.54 46.0 4.01e-01 98.2% 69.4%
5075100 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.53 43.0 4.47e-01 99.1% 97.0%
4405682 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.53 46.0 3.95e-01 98.2% 67.6%
4079488 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.53 46.0 3.85e-01 95.5% 67.9%
4297794 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.53 47.0 3.54e-01 99.1% 66.8%
4294933 223.1.1.7 a+b three layers › Profilin-like › sensor domains › sensor domains › Autoind_bind 0.53 40.0 3.46e-01 79.1% 87.6%
1907312 223.1.1.7 a+b three layers › Profilin-like › sensor domains › sensor domains › Autoind_bind 0.52 39.0 3.36e-01 78.2% 89.0%
3407363 223.2.1.10 a+b three layers › Profilin-like › profilin-like › profilin-like › Gtr1_RagA 0.52 42.0 3.89e-01 89.1% 94.5%
4136386 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.51 42.0 3.64e-01 88.2% 82.9%
3201303 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.51 44.0 3.47e-01 99.1% 79.2%
5065367 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.50 35.0 3.29e-01 71.8% 98.5%
D2 medium residues 122-183
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ermB00 1.10.10.710 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like 0.72 52.0 5.16e-01 91.9% 73.4%
1x42A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.68 47.0 4.29e-01 72.6% 67.5%
3sqnA02 1.10.1790.40 Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › 0.66 50.0 4.17e-01 85.5% 78.8%
4ye6A01 1.10.8.1290 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1 0.66 51.0 4.26e-01 82.3% 74.0%
1ukfA00 3.90.70.20 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.66 52.0 3.64e-01 85.5% 34.6%
3anpB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 57.0 4.05e-01 100.0% 44.3%
3b0cW00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.64 47.0 4.44e-01 77.4% 80.8%
4k22B01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.63 47.0 3.17e-01 80.6% 27.3%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 56.0 4.22e-01 100.0% 60.8%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.61 39.0 3.85e-01 72.6% 62.1%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.60 43.0 3.95e-01 75.8% 75.6%
1gvfB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.59 47.0 3.08e-01 85.5% 88.7%
1q1vA00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.58 37.0 3.64e-01 87.1% 58.6%
3ikhA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.58 46.0 2.99e-01 87.1% 26.9%
3pfyA02 6.10.20.180 Special › Helix non-globular › Arc Repressor Mutant, subunit A › 0.58 41.0 4.29e-01 82.3% 84.2%
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.58 45.0 4.23e-01 85.5% 72.0%
3fmcC01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.57 42.0 2.73e-01 79.0% 35.9%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.57 44.0 4.17e-01 83.9% 73.3%
5oklA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.57 52.0 4.37e-01 100.0% 94.1%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.56 41.0 3.42e-01 79.0% 79.3%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.56 39.0 3.55e-01 74.2% 61.2%
1tw9F02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 38.0 3.23e-01 75.8% 85.1%
1gcvB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 46.0 3.66e-01 100.0% 92.6%
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.54 37.0 3.81e-01 87.1% 77.2%
2kr6A01 1.10.472.100 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Presenilin 0.54 42.0 3.55e-01 87.1% 62.3%
1t07A00 1.10.3880.10 Mainly Alpha › Orthogonal Bundle › YggX-like › Fe(II) trafficking protein YggX 0.53 43.0 4.03e-01 95.2% 87.7%
5cvmA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.53 41.0 2.64e-01 83.9% 29.5%
4hstB03 1.10.1400.10 Mainly Alpha › Orthogonal Bundle › Penicillin amidase (Acylase) alpha subunit, N-terminal domain › Aminohydrolase, alpha-helical knob region 0.52 43.0 3.50e-01 98.4% 69.8%
6z0fA02 1.25.40.680 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain 0.52 38.0 2.84e-01 80.6% 59.6%
2w9mB01 1.10.150.110 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like 0.50 41.0 3.78e-01 93.5% 94.2%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3198596 592.1.1.6 alpha arrays › PWI domain-like › PWI domain › PWI domain › Nab2 0.78 57.0 4.88e-01 90.3% 50.5%
3518379 3502.1.1.1 alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG 0.71 54.0 5.68e-01 90.3% 90.9%
3405583 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.69 47.0 3.72e-01 91.9% 34.6%
4407077 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.68 47.0 4.32e-01 74.2% 56.2%
414118 191.1.1.46 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_44 0.65 59.0 4.67e-01 100.0% 69.9%
3673248 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.65 48.0 4.46e-01 90.3% 62.5%
4618832 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.63 56.0 4.47e-01 100.0% 62.4%
3184238 146.1.1.1 alpha arrays › Di-copper centre-containing domain › Di-copper centre-containing domain › Di-copper centre-containing domain › Tyrosinase 0.61 48.0 3.00e-01 91.9% 64.4%
4019335 4336.2.1.0 alpha duplicates or obligate multimers › YheA/YmcA-like › Protein SUS1 › Protein SUS1 0.61 43.0 3.58e-01 74.2% 47.3%
4972319 3542.1.1.1 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin 0.61 45.0 2.96e-01 80.6% 41.7%
3223570 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.60 50.0 3.81e-01 90.3% 85.0%
5057640 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.60 47.0 2.88e-01 85.5% 57.8%
3934455 216.1.1.17 a+b two layers › UBC-like › UBC-like › UBC-like › Med15_C 0.60 44.0 3.68e-01 80.6% 62.6%
3730753 7023.1.1.3 alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › MBOAT_2 0.59 45.0 3.34e-01 82.3% 48.8%
3727461 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.59 41.0 3.98e-01 90.3% 64.3%
4359328 142.1.1.44 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › GerPC 0.59 45.0 3.94e-01 85.5% 77.0%
3849112 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.59 48.0 3.22e-01 90.3% 62.6%
4944643 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 43.0 3.54e-01 80.6% 98.3%
3682868 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.57 44.0 3.72e-01 83.9% 89.5%
4264204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.57 43.0 2.84e-01 82.3% 28.4%
3830182 142.1.1.21 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › KIX_2 0.56 41.0 3.89e-01 79.0% 84.0%
3611289 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.56 38.0 2.86e-01 75.8% 29.7%
3690556 148.1.1.0 alpha arrays › Histone-like › Histone-related › Histone 0.56 46.0 4.71e-01 96.8% 96.7%
4232288 4275.1.1.10 alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › NifW 0.56 43.0 4.18e-01 85.5% 87.1%
3200876 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.55 39.0 3.51e-01 87.1% 53.3%
3724838 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.54 47.0 4.51e-01 93.5% 98.6%
4336095 377.5.1.1 few secondary structure elements › Glucocorticoid receptor-like › YggX-like (Pfam 04362) › YggX-like (Pfam 04362) › Iron_traffic 0.54 43.0 3.93e-01 95.2% 80.0%
4569675 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.54 46.0 3.87e-01 95.2% 68.6%
5047089 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.53 38.0 3.13e-01 72.6% 73.6%
3785620 109.4.1.229 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SIL1 0.53 36.0 2.35e-01 71.0% 31.6%
3726168 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.52 34.0 2.76e-01 82.3% 37.3%
3990438 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.52 43.0 3.61e-01 93.5% 82.7%
1388524 243.17.1.1 a+b two layers › Cystatin-like › C-terminal domain of PatG › C-terminal domain of PatG › PatG_C 0.52 40.0 3.27e-01 88.7% 77.7%
3490874 5068.1.1.1 alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Cytochrom_B_C 0.50 37.0 3.13e-01 79.0% 74.3%
5019353 2498.1.1.10 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.50 38.0 2.65e-01 83.9% 79.1%
3297761 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.50 44.0 2.43e-01 100.0% 32.4%