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JM123
Euk-VirMacaca_fuscata_rhadinovirus
JM123__YP_238426__Macaca_fuscata_rhadinovirus__272551
Identity
- Accession:
- YP_238426 ↗
- Protein ID:
- JM123
- Kingdom:
- euk
Quality
78.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Macaca_fuscata_rhadinovirus
TaxID: 272551
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 19-187
Domain cluster:
rep: tegument_protein__YP_010087505__Phascolarctid_gammaherpesvirus_1__2249313__D1-176
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 98.5 | 4.00e-28 | 99.4% | 18.3% |
D2
high
residues 499-654
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 170.5 | 7.20e-50 | 98.7% | 15.9% |
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 29.0 | 4.81e-01 | 84.0% | 96.6% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 28.0 | 4.35e-01 | 84.0% | 87.9% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.69 | 28.0 | 4.11e-01 | 82.7% | 85.1% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.61 | 28.0 | 3.85e-01 | 89.1% | 89.2% |
| 1k3kA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.61 | 34.0 | 3.58e-01 | 76.9% | 58.2% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.60 | 47.0 | 4.51e-01 | 80.8% | 79.2% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.60 | 42.0 | 4.82e-01 | 76.3% | 99.1% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.60 | 45.0 | 4.27e-01 | 78.2% | 69.0% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.59 | 47.0 | 3.70e-01 | 85.3% | 98.2% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.58 | 43.0 | 4.61e-01 | 80.8% | 91.0% |
| 3t9oB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.58 | 41.0 | 4.63e-01 | 73.1% | 96.7% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.57 | 43.0 | 4.36e-01 | 79.5% | 77.2% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 40.0 | 4.47e-01 | 75.0% | 91.7% |
| 1x5bA01 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.57 | 36.0 | 3.91e-01 | 80.8% | 74.1% |
| 2l7nA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.56 | 45.0 | 4.40e-01 | 83.3% | 79.8% |
| 4gycA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 45.0 | 4.02e-01 | 84.6% | 70.5% |
| 1st6A03 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.56 | 44.0 | 3.93e-01 | 84.6% | 98.7% |
| 4j8sA00 | 1.25.40.840 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › CCR4-NOT transcription complex subunit 1 TTP binding domain | 0.55 | 39.0 | 3.80e-01 | 73.1% | 83.3% |
| 4iluA02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.54 | 34.0 | 3.96e-01 | 91.0% | 87.4% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.54 | 33.0 | 3.80e-01 | 89.7% | 84.4% |
| 3a7kB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 42.0 | 3.57e-01 | 82.7% | 74.4% |
| 1yhuB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 34.0 | 3.53e-01 | 91.0% | 68.8% |
| 3ay5A02 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.52 | 38.0 | 3.75e-01 | 73.7% | 96.4% |
| 2zs0A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 33.0 | 3.52e-01 | 90.4% | 69.3% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.51 | 28.0 | 3.59e-01 | 89.1% | 94.1% |
| 1sqmA04 | 1.25.40.320 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain | 0.51 | 38.0 | 3.92e-01 | 85.3% | 80.5% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.51 | 37.0 | 3.74e-01 | 75.0% | 81.8% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5028077 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.67 | 33.0 | 3.92e-01 | 72.4% | 67.3% |
| 4102845 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.63 | 45.0 | 5.08e-01 | 76.3% | 95.0% |
| 3453619 | 601.4.1.12 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B | 0.61 | 47.0 | 4.77e-01 | 80.8% | 86.5% |
| 3579457 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.60 | 45.0 | 4.47e-01 | 78.2% | 73.9% |
| 4020237 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.59 | 48.0 | 3.68e-01 | 85.9% | 77.2% |
| 3253938 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.58 | 41.0 | 4.66e-01 | 73.1% | 98.3% |
| 4024030 | 192.29.1.104 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4149 | 0.58 | 46.0 | 4.18e-01 | 83.3% | 91.2% |
| 3733266 | 3352.1.1.19 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › Mannosyl_trans2 | 0.57 | 45.0 | 3.32e-01 | 83.3% | 82.6% |
| 5045257 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.56 | 40.0 | 3.68e-01 | 72.4% | 86.5% |
| 5000576 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.56 | 45.0 | 3.41e-01 | 85.3% | 79.5% |
| 3214019 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.56 | 45.0 | 3.51e-01 | 85.3% | 83.6% |
| 3207860 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.55 | 39.0 | 3.79e-01 | 73.7% | 66.3% |
| 4999478 | 3352.1.1.2 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 | 0.55 | 43.0 | 3.33e-01 | 84.0% | 92.7% |
| 3233225 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.54 | 39.0 | 3.20e-01 | 75.0% | 81.7% |
| 3410368 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 41.0 | 2.64e-01 | 80.1% | 23.6% |
| 3937209 | 5001.1.1.27 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Sre | 0.53 | 43.0 | 3.59e-01 | 84.0% | 88.8% |
| 3789965 | 109.3.1.167 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ion_trans, TRPM2 | 0.53 | 42.0 | 2.82e-01 | 84.6% | 85.5% |
| 3218671 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.51 | 40.0 | 3.24e-01 | 84.0% | 81.6% |
| 3306356 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 41.0 | 4.04e-01 | 88.5% | 84.2% |
D3
medium
residues 339-466
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 121.2 | 5.70e-35 | 100.0% | 14.7% |
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4me9B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 44.0 | 3.90e-01 | 76.6% | 69.9% |
| 2lquA01 | 1.20.1420.40 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein | 0.58 | 43.0 | 4.09e-01 | 77.3% | 75.3% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.56 | 42.0 | 4.24e-01 | 78.9% | 94.5% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.55 | 45.0 | 4.76e-01 | 99.2% | 100.0% |
| 3f0cA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 40.0 | 3.89e-01 | 77.3% | 74.3% |
| 1ihgA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 44.0 | 4.23e-01 | 85.9% | 84.8% |
| 3ihvA03 | 1.25.40.900 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 34.0 | 3.33e-01 | 80.5% | 58.3% |
| 2okcB01 | 1.20.1260.30 | Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain | 0.53 | 33.0 | 3.42e-01 | 96.1% | 65.0% |
| 1yz5B00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.51 | 42.0 | 3.53e-01 | 91.4% | 56.3% |
| 5oklA01 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.50 | 37.0 | 4.09e-01 | 91.4% | 97.0% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1283715 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.80 | 65.0 | 4.25e-01 | 100.0% | 22.4% |
| 3475116 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 47.0 | 4.73e-01 | 71.1% | 75.4% |
| 3689712 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.66 | 46.0 | 3.90e-01 | 71.9% | 51.6% |
| 3431182 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.60 | 48.0 | 4.65e-01 | 100.0% | 75.2% |
| 3645751 | 633.26.1.0 ↗ | alpha bundles › Bromodomain-like › SidC lipid-binding domain › SidC lipid-binding domain | 0.60 | 48.0 | 4.62e-01 | 100.0% | 74.5% |
| 4343390 | 109.4.1.451 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Iml2-TPR_39 | 0.58 | 52.0 | 3.33e-01 | 100.0% | 61.2% |
| 3207289 | 109.4.1.330 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BIG2_C | 0.58 | 48.0 | 4.08e-01 | 88.3% | 65.9% |
| 3665769 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 48.0 | 4.12e-01 | 88.3% | 69.7% |
| 4579761 | 5069.1.1.1 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrome_B | 0.56 | 41.0 | 3.49e-01 | 78.1% | 55.8% |
| 3664577 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.54 | 34.0 | 3.48e-01 | 75.8% | 65.0% |
| 3412240 | 174.1.1.33 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Erg28 | 0.52 | 45.0 | 4.53e-01 | 94.5% | 93.8% |
| 3744245 | 109.4.1.1935 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF2428, TPR_Trm732, PF26523 | 0.51 | 44.0 | 2.72e-01 | 100.0% | 13.4% |
| 3884394 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.51 | 37.0 | 3.81e-01 | 83.6% | 78.4% |
| 4027931 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 40.0 | 3.19e-01 | 84.4% | 60.0% |
| 4933307 | 174.1.1.96 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27307 | 0.51 | 42.0 | 4.00e-01 | 93.8% | 91.9% |
| 3207001 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.51 | 43.0 | 4.21e-01 | 93.0% | 92.1% |
| 3936400 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 40.0 | 2.80e-01 | 86.7% | 24.4% |
| 3890042 | 109.4.1.1674 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30746 | 0.50 | 42.0 | 2.85e-01 | 92.2% | 51.6% |
D4
medium
residues 829-854_903-939